CSMD2 (CUB and Sushi multiple domains 2) - Rat Genome Database

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Gene: CSMD2 (CUB and Sushi multiple domains 2) Canis lupus familiaris
Analyze
Symbol: CSMD2
Name: CUB and Sushi multiple domains 2
RGD ID: 12252081
Description: ENCODES a protein that exhibits serine-type peptidase activity (inferred); INVOLVED IN maintenance of postsynaptic density structure (inferred); postsynaptic density assembly (inferred); ASSOCIATED WITH attention deficit hyperactivity disorder (ortholog); autistic disorder (ortholog); Charcot-Marie-Tooth disease dominant intermediate C (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic density membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CUB and sushi domain-containing protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1157,753,901 - 8,191,506 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha157,997,160 - 8,382,285 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0157,899,049 - 8,343,901 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl157,888,699 - 8,343,903 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1157,905,652 - 8,116,554 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0157,815,247 - 8,253,359 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0157,830,746 - 8,268,735 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
CSMD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1157,753,901 - 8,191,506 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha157,997,160 - 8,382,285 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0157,899,049 - 8,343,901 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl157,888,699 - 8,343,903 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1157,905,652 - 8,116,554 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0157,815,247 - 8,253,359 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0157,830,746 - 8,268,735 (+)NCBIUU_Cfam_GSD_1.0
CSMD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38133,513,998 - 34,165,842 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl133,513,998 - 34,165,842 (-)EnsemblGRCh38hg38GRCh38
GRCh37133,979,598 - 34,631,443 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36133,752,196 - 34,404,030 (-)NCBINCBI36Build 36hg18NCBI36
Build 34133,648,701 - 34,300,536NCBI
Celera132,251,406 - 32,903,645 (-)NCBICelera
Cytogenetic Map1p35.1NCBI
HuRef132,095,768 - 32,747,734 (-)NCBIHuRef
CHM1_1134,095,005 - 34,746,840 (-)NCBICHM1_1
T2T-CHM13v2.0133,375,608 - 34,027,570 (-)NCBIT2T-CHM13v2.0
Csmd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394127,880,310 - 128,461,459 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4127,881,650 - 128,461,449 (+)EnsemblGRCm39 Ensembl
GRCm384127,986,505 - 128,567,660 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4127,987,857 - 128,567,656 (+)EnsemblGRCm38mm10GRCm38
MGSCv374127,665,294 - 128,245,100 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera4126,322,889 - 126,895,394 (+)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map461.65NCBI
Csmd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85145,626,823 - 146,196,815 (+)NCBIGRCr8
mRatBN7.25140,342,352 - 140,912,422 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5140,342,376 - 140,912,234 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.05146,091,167 - 146,743,436 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5146,383,942 - 146,739,418 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05150,125,998 - 150,480,769 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45147,393,098 - 147,789,300 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5138,832,888 - 139,396,715 (+)NCBICelera
Cytogenetic Map5q36NCBI
Csmd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545211,695,182 - 12,274,450 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545211,695,182 - 12,274,450 (-)NCBIChiLan1.0ChiLan1.0
CSMD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21192,669,104 - 193,312,556 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11191,791,148 - 192,434,700 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0132,800,267 - 33,443,599 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1133,984,656 - 34,625,977 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl133,989,876 - 34,625,977 (-)Ensemblpanpan1.1panPan2
Csmd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505850,498,763 - 50,982,232 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647416,326,666 - 16,866,720 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647416,323,899 - 16,607,712 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CSMD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1689,778,338 - 90,424,979 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2683,782,065 - 83,802,730 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CSMD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12098,708,384 - 99,358,093 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2098,936,373 - 99,352,601 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603317,336,998 - 18,008,225 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Csmd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476416,600,854 - 17,179,612 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476416,597,719 - 17,179,729 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CSMD2
8314 total Variants

Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCAFT00845028194   ⟹   ENSCAFP00845022185
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl157,888,699 - 8,343,903 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845028509   ⟹   ENSCAFP00845022426
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl157,888,699 - 8,343,903 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845029021   ⟹   ENSCAFP00845022826
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl157,888,815 - 8,255,971 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845029138   ⟹   ENSCAFP00845022917
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl158,017,984 - 8,343,903 (+)Ensembl
RefSeq Acc Id: XM_038451771   ⟹   XP_038307699
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha157,997,160 - 8,382,285 (+)NCBI
RefSeq Acc Id: XM_038496779   ⟹   XP_038352707
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1157,905,652 - 8,116,554 (+)NCBI
RefSeq Acc Id: XM_038557633   ⟹   XP_038413561
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0157,830,746 - 8,268,735 (+)NCBI
RefSeq Acc Id: XM_038621529   ⟹   XP_038477457
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0157,815,247 - 8,253,359 (+)NCBI
RefSeq Acc Id: XM_038687301   ⟹   XP_038543229
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0157,899,049 - 8,343,901 (+)NCBI
RefSeq Acc Id: XP_038352707   ⟸   XM_038496779
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038477457   ⟸   XM_038621529
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038543229   ⟸   XM_038687301
- Peptide Label: isoform X1
- UniProtKB: A0A8I3RZ09 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038307699   ⟸   XM_038451771
- Peptide Label: isoform X5
- UniProtKB: A0A8I3RZ37 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038413561   ⟸   XM_038557633
- Peptide Label: isoform X4
- UniProtKB: A0A8I3RZ09 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845022426   ⟸   ENSCAFT00845028509
Ensembl Acc Id: ENSCAFP00845022917   ⟸   ENSCAFT00845029138
Ensembl Acc Id: ENSCAFP00845022826   ⟸   ENSCAFT00845029021
Ensembl Acc Id: ENSCAFP00845022185   ⟸   ENSCAFT00845028194
Protein Domains
CUB   Sushi


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000048780 UniProtKB/TrEMBL
  ENSCAFG00845015809 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000069715.2 UniProtKB/TrEMBL
  ENSCAFT00000097022.1 UniProtKB/TrEMBL
  ENSCAFT00845028194 ENTREZGENE
  ENSCAFT00845028194.1 UniProtKB/TrEMBL
  ENSCAFT00845028509.1 UniProtKB/TrEMBL
  ENSCAFT00845029021.1 UniProtKB/TrEMBL
  ENSCAFT00845029138.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.290 UniProtKB/TrEMBL
  Complement Module, domain 1 UniProtKB/TrEMBL
InterPro CUB_dom UniProtKB/TrEMBL
  SEZ6_CSMD_C4BPB_Regulators UniProtKB/TrEMBL
  Sperma_CUB_dom_sf UniProtKB/TrEMBL
  Sushi/SCR/CCP_sf UniProtKB/TrEMBL
  Sushi_SCR_CCP_dom UniProtKB/TrEMBL
NCBI Gene CSMD2 ENTREZGENE
PANTHER CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
  CUBILIN UniProtKB/TrEMBL
  CUBILIN UniProtKB/TrEMBL
  PROTEIN CBR-CLEC-78 UniProtKB/TrEMBL
  PTHR45656:SF15 UniProtKB/TrEMBL
Pfam CUB UniProtKB/TrEMBL
  Sushi UniProtKB/TrEMBL
PROSITE CUB UniProtKB/TrEMBL
  SUSHI UniProtKB/TrEMBL
SMART CCP UniProtKB/TrEMBL
  CUB UniProtKB/TrEMBL
Superfamily-SCOP SSF49854 UniProtKB/TrEMBL
  SSF57535 UniProtKB/TrEMBL
UniProt A0A8I3NQH7_CANLF UniProtKB/TrEMBL
  A0A8I3RZ09 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RZ37 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RZ91_CANLF UniProtKB/TrEMBL
  A0A8P0P0L4_CANLF UniProtKB/TrEMBL
  A0A8P0PQT4_CANLF UniProtKB/TrEMBL