LRRTM2 (leucine rich repeat transmembrane neuronal 2) - Rat Genome Database

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Gene: LRRTM2 (leucine rich repeat transmembrane neuronal 2) Canis lupus familiaris
Analyze
Symbol: LRRTM2
Name: leucine rich repeat transmembrane neuronal 2
RGD ID: 12376822
Description: ENCODES a protein that exhibits neurexin family protein binding (ortholog); INVOLVED IN long-term synaptic potentiation (ortholog); negative regulation of receptor internalization (ortholog); positive regulation of synapse assembly (ortholog); ASSOCIATED WITH autosomal dominant non-syndromic intellectual disability 31 (ortholog); autosomal dominant nonsyndromic deafness 1 (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN glutamatergic synapse (ortholog); hippocampal mossy fiber to CA3 synapse (ortholog); integral component of postsynaptic density membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: leucine-rich repeat transmembrane neuronal protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11126,392,642 - 26,397,018 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1126,392,734 - 26,396,223 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1125,159,555 - 25,163,871 (-)NCBI
ROS_Cfam_1.01127,248,202 - 27,252,518 (-)NCBI
UMICH_Zoey_3.11125,955,564 - 25,959,881 (-)NCBI
UNSW_CanFamBas_1.01125,775,869 - 25,782,210 (-)NCBI
UU_Cfam_GSD_1.01126,442,410 - 26,446,727 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
LRRTM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11126,392,642 - 26,397,018 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1126,392,734 - 26,396,223 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1125,159,555 - 25,163,871 (-)NCBI
ROS_Cfam_1.01127,248,202 - 27,252,518 (-)NCBI
UMICH_Zoey_3.11125,955,564 - 25,959,881 (-)NCBI
UNSW_CanFamBas_1.01125,775,869 - 25,782,210 (-)NCBI
UU_Cfam_GSD_1.01126,442,410 - 26,446,727 (-)NCBI
LRRTM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5138,868,921 - 138,875,368 (-)EnsemblGRCh38hg38GRCh38
GRCh385138,868,921 - 138,875,335 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375138,204,610 - 138,211,024 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365138,232,978 - 138,238,908 (-)NCBINCBI36hg18NCBI36
Build 345138,232,977 - 138,238,908NCBI
Celera5134,326,860 - 134,332,826 (-)NCBI
Cytogenetic Map5q31.2NCBI
HuRef5133,394,868 - 133,400,836 (-)NCBIHuRef
CHM1_15137,637,719 - 137,643,697 (-)NCBICHM1_1
Lrrtm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391835,342,056 - 35,348,077 (-)NCBIGRCm39mm39
GRCm39 Ensembl1835,342,056 - 35,348,077 (-)Ensembl
GRCm381835,209,003 - 35,215,024 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1835,209,003 - 35,215,024 (-)EnsemblGRCm38mm10GRCm38
MGSCv371835,368,657 - 35,374,678 (-)NCBIGRCm37mm9NCBIm37
MGSCv361835,336,885 - 35,340,892 (-)NCBImm8
Celera1835,664,662 - 35,670,684 (-)NCBICelera
Cytogenetic Map18B1NCBI
Lrrtm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21826,817,816 - 26,822,864 (-)NCBI
Rnor_6.0 Ensembl1828,012,877 - 28,017,925 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01828,012,877 - 28,017,925 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01827,722,686 - 27,727,734 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41827,722,717 - 27,727,765 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1826,552,974 - 26,558,022 (-)NCBICelera
Cytogenetic Map18p11NCBI
Lrrtm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554181,636,828 - 1,643,588 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554181,636,906 - 1,643,430 (+)NCBIChiLan1.0ChiLan1.0
LRRTM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15140,373,790 - 140,380,127 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v05134,247,933 - 134,254,188 (-)NCBIMhudiblu_PPA_v0panPan3
Lrrtm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213153,637,684 - 153,641,722 (+)NCBI
SpeTri2.0NW_0049365317,968,111 - 7,973,823 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRRTM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2140,803,120 - 140,809,495 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12140,803,624 - 140,810,013 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22146,698,365 - 146,704,568 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LRRTM2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12341,534,757 - 41,540,372 (-)NCBI
ChlSab1.1 Ensembl2341,533,973 - 41,539,915 (-)Ensembl
Lrrtm2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474331,648,543 - 31,651,772 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6
Low 4 8 6
Below cutoff 1 5 14 6 6 6 6 4 8 10 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000045677   ⟹   ENSCAFP00000037101
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1126,392,734 - 26,396,223 (-)Ensembl
RefSeq Acc Id: XM_038490233   ⟹   XP_038346161
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11125,955,564 - 25,959,881 (-)NCBI
RefSeq Acc Id: XM_038552317   ⟹   XP_038408245
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01126,442,410 - 26,446,727 (-)NCBI
RefSeq Acc Id: XM_038616182   ⟹   XP_038472110
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01125,775,869 - 25,782,210 (-)NCBI
RefSeq Acc Id: XM_038681675   ⟹   XP_038537603
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01127,248,202 - 27,252,518 (-)NCBI
RefSeq Acc Id: XM_538650   ⟹   XP_538650
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11126,392,642 - 26,397,018 (-)NCBI
Dog10K_Boxer_Tasha1125,159,555 - 25,163,871 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_038346161 (Get FASTA)   NCBI Sequence Viewer  
  XP_038408245 (Get FASTA)   NCBI Sequence Viewer  
  XP_038472110 (Get FASTA)   NCBI Sequence Viewer  
  XP_038537603 (Get FASTA)   NCBI Sequence Viewer  
  XP_538650 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_538650   ⟸   XM_538650
- UniProtKB: J9NVA9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000037101   ⟸   ENSCAFT00000045677
RefSeq Acc Id: XP_038346161   ⟸   XM_038490233
RefSeq Acc Id: XP_038472110   ⟸   XM_038616182
RefSeq Acc Id: XP_038537603   ⟸   XM_038681675
RefSeq Acc Id: XP_038408245   ⟸   XM_038552317


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000032660 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000037101 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000045677 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro L_dom-like UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
KEGG Report cfa:481529 UniProtKB/TrEMBL
NCBI Gene LRRTM2 ENTREZGENE
Pfam LRR_8 UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
SMART LRR_TYP UniProtKB/TrEMBL
UniProt J9NVA9 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:42830 ENTREZGENE