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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of inflammasome-mediated signaling pathway
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Accession:GO:0141086 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of an inflammasome-mediated signaling pathway.
Synonyms:exact_synonym: negative regulation of inflammasome-mediated signal transduction


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negative regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trim11 tripartite motif-containing 11 involved_in ISS
ISO		 GO_REF:0000024
(PMID:27498865)		 UniProt
RGD		 PMID:27498865 GO_REF:0000024 NCBI chr10:43,758,299...43,771,138
Ensembl chr10:43,758,354...43,771,138 		JBrowse link
negative regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd17a abhydrolase domain containing 17A, depalmitoylase involved_in ISO (PMID:38092000) RGD PMID:38092000 NCBI chr 7:9,124,332...9,132,762
Ensembl chr 7:9,124,332...9,130,762 		JBrowse link
G Cptp ceramide-1-phosphate transfer protein involved_in ISO
ISS		 (PMID:29164996)
GO_REF:0000024		 RGD
UniProt		 PMID:29164996 GO_REF:0000024 NCBI chr 5:166,474,947...166,479,103
Ensembl chr 5:166,474,966...166,479,017 		JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6787653|PMID:34615873)		 UniProt
RGD		 PMID:34615873 GO_REF:0000024 MGI:6787653 NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271 		JBrowse link
G Fbxl2 F-box and leucine-rich repeat protein 2 involved_in ISO (PMID:26037928) RGD PMID:26037928 NCBI chr 8:113,916,660...113,965,137
Ensembl chr 8:113,913,373...113,965,066 		JBrowse link
G Haus8l2 HAUS augmin-like complex, subunit 8 like 2 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr11:5,628,432...5,630,535
Ensembl chr11:5,628,427...5,630,533 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 involved_in ISO
IEA		 (PMID:36586411)
GO_REF:0000107		 RGD
Ensembl		 PMID:36586411 GO_REF:0000107 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Irgm immunity-related GTPase M involved_in ISS
ISO		 GO_REF:0000024
(PMID:30612879)
(MGI:6282153|PMID:30612879)		 UniProt
RGD		 PMID:30612879 GO_REF:0000024 MGI:6282153 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 involved_in ISO (PMID:36586411) RGD PMID:36586411 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522 		JBrowse link
G Mefv MEFV innate immunity regulator, pyrin involved_in ISS
ISO		 GO_REF:0000024
(PMID:26347139)		 UniProt
RGD		 PMID:26347139 GO_REF:0000024 NCBI chr10:11,786,948...11,796,977
Ensembl chr10:11,787,422...11,796,973 		JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in ISO (PMID:25277106) RGD PMID:25277106 NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398 		JBrowse link
G Sirt2 sirtuin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:23502856)		 Ensembl
RGD		 PMID:23502856 GO_REF:0000107 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 acts_upstream_of_or_within ISO (MGI:6391726|PMID:29887864)
(PMID:32514138)		 RGD PMID:29887864 PMID:32514138 MGI:6391726 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Trim31 tripartite motif-containing 31 involved_in ISO (PMID:27929086)
(MGI:5907951|PMID:27929086)		 RGD PMID:27929086 MGI:5907951 NCBI chr20:1,653,165...1,666,494
Ensembl chr20:1,653,165...1,666,494 		JBrowse link
G Zdhhc12 zinc finger DHHC-type palmitoyltransferase 12 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:36586411)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:36586411 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:13,363,504...13,366,383
Ensembl chr 3:13,363,504...13,366,474 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    immune system process 3017
      negative regulation of immune system process 567
        negative regulation of cytoplasmic pattern recognition receptor signaling pathway 51
          negative regulation of inflammasome-mediated signaling pathway 15
            negative regulation of AIM2 inflammasome complex assembly 1
            negative regulation of NLRP3 inflammasome complex assembly 14
            negative regulation of non-canonical inflammasome complex assembly 0
Path 2
Term Annotations click to browse term
  biological_process 20413
    response to stimulus 10919
      response to external stimulus 2746
        response to external biotic stimulus 1854
          response to other organism 1850
            defense response to other organism 1305
              defense response to symbiont 1169
                innate immune response 996
                  regulation of innate immune response 458
                    positive regulation of innate immune response 375
                      activation of innate immune response 304
                        innate immune response-activating signaling pathway 278
                          pattern recognition receptor signaling pathway 266
                            cytoplasmic pattern recognition receptor signaling pathway 170
                              regulation of cytoplasmic pattern recognition receptor signaling pathway 116
                                negative regulation of cytoplasmic pattern recognition receptor signaling pathway 51
                                  negative regulation of inflammasome-mediated signaling pathway 15
                                    negative regulation of AIM2 inflammasome complex assembly 1
                                    negative regulation of NLRP3 inflammasome complex assembly 14
                                    negative regulation of non-canonical inflammasome complex assembly 0
paths to the root