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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of NLRP3 inflammasome complex assembly
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Accession:GO:1900226 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly.
Synonyms:exact_synonym: down regulation of NALP3 inflammasome complex assembly;   down regulation of NLRP3 inflammasome complex assembly;   downregulation of NALP3 inflammasome complex assembly;   downregulation of NLRP3 inflammasome complex assembly;   inhibition of NALP3 inflammasome complex assembly;   negative regulation of NALP3 inflammasome complex assembly
 narrow_synonym: inhibition of NLRP3 inflammasome complex assembly
 related_synonym: down regulation of NLRP3 inflammasome activation;   downregulation of NLRP3 inflammasome activation;   inhibition of NLRP3 inflammasome activation;   negative regulation of NLRP3 inflammasome activation



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negative regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd17a abhydrolase domain containing 17A, depalmitoylase involved_in ISO (PMID:38092000) RGD PMID:38092000 NCBI chr 7:9,124,332...9,132,762
Ensembl chr 7:9,124,332...9,130,762
JBrowse link
G Cptp ceramide-1-phosphate transfer protein involved_in ISO
ISS
(PMID:29164996)
GO_REF:0000024
RGD
UniProt
PMID:29164996 GO_REF:0000024 NCBI chr 5:166,474,947...166,479,103
Ensembl chr 5:166,474,966...166,479,017
JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:6787653|PMID:34615873)
UniProt
RGD
PMID:34615873 GO_REF:0000024 MGI:6787653 NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271
JBrowse link
G Fbxl2 F-box and leucine-rich repeat protein 2 involved_in ISO (PMID:26037928) RGD PMID:26037928 NCBI chr 8:113,916,660...113,965,137
Ensembl chr 8:113,913,373...113,965,066
JBrowse link
G Haus8l2 HAUS augmin-like complex, subunit 8 like 2 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr11:5,628,432...5,630,535
Ensembl chr11:5,628,427...5,630,533
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 involved_in ISO
IEA
(PMID:36586411)
GO_REF:0000107
RGD
Ensembl
PMID:36586411 GO_REF:0000107 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Irgm immunity-related GTPase M involved_in ISS
ISO
GO_REF:0000024
(PMID:30612879)
(MGI:6282153|PMID:30612879)
UniProt
RGD
PMID:30612879 GO_REF:0000024 MGI:6282153 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 involved_in ISO (PMID:36586411) RGD PMID:36586411 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522
JBrowse link
G Mefv MEFV innate immunity regulator, pyrin involved_in ISS
ISO
GO_REF:0000024
(PMID:26347139)
UniProt
RGD
PMID:26347139 GO_REF:0000024 NCBI chr10:11,786,948...11,796,977
Ensembl chr10:11,787,422...11,796,973
JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in ISO (PMID:25277106) RGD PMID:25277106 NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398
JBrowse link
G Sirt2 sirtuin 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5488534|PMID:23502856)
GO_REF:0000107
RGD
Ensembl
PMID:23502856 GO_REF:0000107 MGI:5488534 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 acts_upstream_of_or_within ISO (MGI:6391726|PMID:29887864)
(PMID:32514138)
RGD PMID:29887864 PMID:32514138 MGI:6391726 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
G Trim31 tripartite motif-containing 31 involved_in ISO (PMID:27929086)
(MGI:5907951|PMID:27929086)
RGD PMID:27929086 MGI:5907951 NCBI chr20:1,653,165...1,666,494
Ensembl chr20:1,653,165...1,666,494
JBrowse link
G Zdhhc12 zinc finger DHHC-type palmitoyltransferase 12 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:36586411)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:36586411 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:13,363,504...13,366,383
Ensembl chr 3:13,363,504...13,366,474
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20350
    cellular process 18813
      negative regulation of cellular process 5407
        negative regulation of cellular component organization 824
          negative regulation of protein-containing complex assembly 171
            negative regulation of NLRP3 inflammasome complex assembly 14
Path 2
Term Annotations click to browse term
  biological_process 20350
    response to stimulus 10881
      response to biotic stimulus 1880
        response to external biotic stimulus 1838
          response to other organism 1834
            defense response to other organism 1292
              defense response to symbiont 1149
                innate immune response 975
                  regulation of innate immune response 453
                    positive regulation of innate immune response 371
                      activation of innate immune response 300
                        innate immune response-activating signaling pathway 274
                          pattern recognition receptor signaling pathway 262
                            cytoplasmic pattern recognition receptor signaling pathway 166
                              inflammasome-mediated signaling pathway 46
                                canonical inflammasome complex assembly 44
                                  NLRP3 inflammasome complex assembly 42
                                    regulation of NLRP3 inflammasome complex assembly 39
                                      negative regulation of NLRP3 inflammasome complex assembly 14
paths to the root