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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of NLRP3 inflammasome complex assembly
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Accession:GO:1900226 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly.
Synonyms:exact_synonym: down regulation of NALP3 inflammasome complex assembly;   down regulation of NLRP3 inflammasome complex assembly;   downregulation of NALP3 inflammasome complex assembly;   downregulation of NLRP3 inflammasome complex assembly;   inhibition of NALP3 inflammasome complex assembly;   negative regulation of NALP3 inflammasome complex assembly
 narrow_synonym: inhibition of NLRP3 inflammasome complex assembly
 related_synonym: down regulation of NLRP3 inflammasome activation;   downregulation of NLRP3 inflammasome activation;   inhibition of NLRP3 inflammasome activation;   negative regulation of NLRP3 inflammasome activation


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negative regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cptp ceramide-1-phosphate transfer protein involved_in ISO
ISS
(PMID:29164996)
GO_REF:0000024
RGD
UniProt
PMID:29164996 GO_REF:0000024 NCBI chr 5:166,474,947...166,479,103
Ensembl chr 5:166,474,966...166,479,017
JBrowse link
G Mefv MEFV innate immuity regulator, pyrin involved_in ISS
ISO
GO_REF:0000024
(PMID:26347139)
UniProt
RGD
PMID:26347139 GO_REF:0000024 NCBI chr10:11,786,948...11,796,977
Ensembl chr10:11,787,422...11,796,973
JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in ISO (PMID:25277106) RGD PMID:25277106 NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398
JBrowse link
G Nlrp1b NLR family, pyrin domain containing 1B involved_in ISO (PMID:24517500) RGD PMID:24517500 NCBI chr10:55,838,381...55,904,374 JBrowse link
G Sirt2 sirtuin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5488534|PMID:23502856)
Ensembl
RGD
PMID:23502856 GO_REF:0000107 MGI:5488534 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 acts_upstream_of_or_within ISO (MGI:6391726|PMID:29887864)
(PMID:32514138)
RGD PMID:29887864 PMID:32514138 MGI:6391726 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    negative regulation of biological process 5613
      negative regulation of cellular process 5060
        negative regulation of cellular component organization 736
          negative regulation of protein-containing complex assembly 157
            negative regulation of NLRP3 inflammasome complex assembly 6
Path 2
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      cellular component organization or biogenesis 6481
        cellular component organization 6235
          protein-containing complex subunit organization 1805
            protein-containing complex assembly 1595
              cellular protein-containing complex assembly 1113
                inflammasome complex assembly 22
                  NLRP3 inflammasome complex assembly 21
                    regulation of NLRP3 inflammasome complex assembly 19
                      negative regulation of NLRP3 inflammasome complex assembly 6
paths to the root