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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of synapse organization
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Accession:GO:1905809 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization.
Synonyms:exact_synonym: down regulation of synapse development;   down regulation of synapse organisation;   down regulation of synapse organization;   downregulation of synapse development;   downregulation of synapse organisation;   downregulation of synapse organization;   negative regulation of synapse development;   negative regulation of synapse organisation
 narrow_synonym: inhibition of synapse development;   inhibition of synapse organisation;   inhibition of synapse organization
 related_synonym: down regulation of synapse morphogenesis;   down regulation of synapse organization and biogenesis;   downregulation of synapse morphogenesis;   downregulation of synapse organization and biogenesis;   inhibition of synapse morphogenesis;   inhibition of synapse organization and biogenesis;   negative regulation of synapse morphogenesis;   negative regulation of synapse organization and biogenesis


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negative regulation of synapse organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pgrmc1 progesterone receptor membrane component 1 involved_in IGI PMID:25390368 ARUK-UCL PMID:25390368 RGD:12910997 NCBI chr  X:115,832,865...115,841,060
Ensembl chr  X:115,832,884...115,888,682 		JBrowse link
negative regulation of excitatory synapse assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clstn3 calsyntenin 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:35420982)		 UniProt
RGD		 PMID:35420982 GO_REF:0000024 NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769 		JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:23769722 GO_REF:0000033, RGD:152975632 NCBI chr14:6,108,202...6,282,619
Ensembl chr14:6,108,211...6,282,563 		JBrowse link
negative regulation of inhibitory synapse assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbln1 cerebellin 1 precursor involved_in ISS
ISO		 GO_REF:0000024
(PMID:24467251)		 UniProt
RGD		 PMID:24467251 GO_REF:0000024 NCBI chr19:19,608,763...19,612,572
Ensembl chr19:19,608,716...19,612,572 		JBrowse link
negative regulation of neuromuscular junction development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptn pleiotrophin IDA RGD PMID:7722643 RGD:9834945 NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456 		JBrowse link
negative regulation of postsynaptic membrane organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:24259049) RGD PMID:24259049 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
negative regulation of presynapse assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:30902970)
GO_REF:0000107		 RGD
Ensembl		 PMID:30902970 GO_REF:0000107 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:29643768) RGD PMID:29643768 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
negative regulation of synapse assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epha7 Eph receptor A7 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19036963)		 Ensembl
RGD		 PMID:19036963 GO_REF:0000107 NCBI chr 5:42,975,353...43,128,703
Ensembl chr 5:42,975,405...43,127,112 		JBrowse link
G Mdga1 MAM domain containing glycosylphosphatidylinositol anchor 1 IDA RGD PMID:23358245 RGD:9743980 NCBI chr20:7,900,327...7,964,309
Ensembl chr20:7,904,358...7,963,471 		JBrowse link
G Ptk2 protein tyrosine kinase 2 acts_upstream_of_or_within ISO MGI:1857596 (PMID:15378065) RGD PMID:15378065 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Rhoa ras homolog family member A IMP RGD PMID:27893610 RGD:243048440 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Robo1 roundabout guidance receptor 1 IMP RGD PMID:27893610 RGD:243048440 NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Slit1 slit guidance ligand 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:240,409,559...240,558,127
Ensembl chr 1:240,409,561...240,558,127 		JBrowse link
G Tlr2 toll-like receptor 2 involved_in ISO UniProtKB:P05067|UniProtKB:P49768 (PMID:22198949) RGD PMID:22198949 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Wnt5a Wnt family member 5A involved_in IEA
ISO		 GO_REF:0000107
(PMID:18986540)		 Ensembl
RGD		 PMID:18986540 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
negative regulation of synapse maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef15 Rho guanine nucleotide exchange factor 15 involved_in ISO (PMID:21029865) RGD PMID:21029865 NCBI chr10:53,650,521...53,663,269
Ensembl chr10:53,650,553...53,663,913 		JBrowse link
G Neurod2 neuronal differentiation 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19900895)		 UniProt
Ensembl
RGD		 PMID:19900895 GO_REF:0000024 GO_REF:0000107 NCBI chr10:83,323,801...83,327,986
Ensembl chr10:83,324,442...83,327,986 		JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 acts_upstream_of_or_within ISO (PMID:23407945) RGD PMID:23407945 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610 		JBrowse link
negative regulation of synaptic assembly at neuromuscular junction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsk3b glycogen synthase kinase 3 beta involved_in IMP PMID:25764078 CACAO PMID:25764078 RGD:15023478 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20228
    cellular process 19289
      negative regulation of cellular process 5538
        negative regulation of cellular component organization 799
          negative regulation of synapse organization 20
            negative regulation of neuromuscular junction development + 2
            negative regulation of postsynaptic membrane organization + 1
            negative regulation of presynaptic membrane organization 0
            negative regulation of synapse assembly + 14
            negative regulation of synapse maturation 3
            negative regulation of synapse pruning + 0
Path 2
Term Annotations click to browse term
  biological_process 20228
    cellular process 19289
      cellular component organization or biogenesis 7192
        cellular component organization 6935
          cell junction organization 978
            synapse organization 699
              regulation of synapse organization 408
                negative regulation of synapse organization 20
                  negative regulation of neuromuscular junction development + 2
                  negative regulation of postsynaptic membrane organization + 1
                  negative regulation of presynaptic membrane organization 0
                  negative regulation of synapse assembly + 14
                  negative regulation of synapse maturation 3
                  negative regulation of synapse pruning + 0
paths to the root