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ONTOLOGY REPORT - ANNOTATIONS


Term:endothelin receptor signaling pathway
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Accession:GO:0086100 term browser browse the term
Definition:A G protein-coupled receptor signaling pathway initiated by endothelin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:related_synonym: endothelin signaling pathway



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endothelin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcar1 BCAR1 scaffold protein, Cas family member involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:19086031)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:19086031 GO_REF:0000024 GO_REF:0000107 NCBI chr19:39,679,215...39,713,907
Ensembl chr19:39,679,204...39,713,907
JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member involved_in ISO
IBA
(PMID:19086031)
GO_REF:0000033
RGD
GO_Central
PMID:19086031 GO_REF:0000033 NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO MGI:5510713 (PMID:25565927) RGD PMID:25565927 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238
JBrowse link
G Dear dual endothelin 1, angiotensin II receptor involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 2:170,296,930...170,300,182
Ensembl chr 2:170,296,930...170,300,182
JBrowse link
G Edn1 endothelin 1 involved_in ISO
ISS
(PMID:19086031)
(PMID:24722437)
GO_REF:0000024
RGD
UniProt
PMID:19086031 PMID:24722437 GO_REF:0000024 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A involved_in IEA
ISO
IBA
GO_REF:0000108
MGI:102720 (PMID:24722437)
GO_REF:0000033
GOC
RGD
GO_Central
PMID:24722437 GO_REF:0000033 GO_REF:0000108 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Ednrb endothelin receptor type B involved_in ISO
IBA
(PMID:1713452), (PMID:19767294), (PMID:28236341)
MGI:105923 (PMID:24722437)
GO_REF:0000033
RGD
GO_Central
PMID:1713452 PMID:19767294 PMID:24722437 PMID:28236341 GO_REF:0000033 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
JBrowse link
G Gna11 G protein subunit alpha 11 involved_in IEA
ISO
GO_REF:0000107
MGI:95776 (PMID:18199583)
Ensembl
RGD
PMID:18199583 GO_REF:0000107 NCBI chr 7:8,163,520...8,177,863
Ensembl chr 7:8,162,750...8,179,812
JBrowse link
G Gnaq G protein subunit alpha q involved_in IEA
ISO
GO_REF:0000107
MGI:95766 (PMID:18199583)
Ensembl
RGD
PMID:18199583 GO_REF:0000107 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in ISO
ISS
(PMID:19086031)
GO_REF:0000024
RGD
UniProt
PMID:19086031 GO_REF:0000024 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
G Six1 SIX homeobox 1 involved_in ISO MGI:3612276 (PMID:28455376) RGD PMID:28455376 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975
JBrowse link
endothelin receptor signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc42 cell division cycle 42 involved_in ISO (PMID:31219639) RGD PMID:31219639 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Edn1 endothelin 1 involved_in ISO (PMID:31219639) RGD PMID:31219639 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A involved_in IEA
ISO
GO_REF:0000107
MGI:2687362 (PMID:31219639)
Ensembl
RGD
PMID:31219639 GO_REF:0000107 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
phospholipase C-activating endothelin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plcb4 phospholipase C, beta 4 involved_in ISS
ISO
GO_REF:0000024
(PMID:35284927)
UniProt
RGD
PMID:35284927 GO_REF:0000024 NCBI chr 3:122,952,965...123,322,522
Ensembl chr 3:122,953,196...123,322,392
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20228
    cellular process 19289
      signal transduction 7199
        G protein-coupled receptor signaling pathway 2461
          endothelin receptor signaling pathway 13
            endothelin receptor signaling pathway involved in heart process 3
            phospholipase C-activating endothelin receptor signaling pathway 1
Path 2
Term Annotations click to browse term
  biological_process 20228
    biological regulation 13626
      regulation of biological process 13203
        signaling 7760
          signal transduction 7199
            G protein-coupled receptor signaling pathway 2461
              endothelin receptor signaling pathway 13
                endothelin receptor signaling pathway involved in heart process 3
                phospholipase C-activating endothelin receptor signaling pathway 1
paths to the root