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ONTOLOGY REPORT - ANNOTATIONS

Term:cardiac myofibril assembly
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Accession:GO:0055003 term browser browse the term
Definition:The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.
Synonyms:exact_synonym: cardiac myofibril development;   cardiac myofibril morphogenesis
 related_synonym: heart myofibril assembly


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cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actc1 actin, alpha, cardiac muscle 1 acts_upstream_of_or_within ISO MGI:2180072 (PMID:9114002) RGD PMID:9114002 NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523 		JBrowse link
G Adprhl1 ADP-ribosylhydrolase like 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr16:76,283,186...76,315,075
Ensembl chr16:76,283,103...76,354,440 		JBrowse link
G Csrp3 cysteine and glycine rich protein 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:2447926|PMID:12507422)		 Ensembl
RGD		 PMID:12507422 GO_REF:0000107 MGI:2447926 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653 		JBrowse link
G Fhod3 formin homology 2 domain containing 3 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:5440613 (PMID:23213483)		 GO_Central
RGD		 PMID:23213483 GO_REF:0000033 NCBI chr18:15,993,079...16,425,796
Ensembl chr18:15,993,324...16,425,796 		JBrowse link
G Myh10 myosin heavy chain 10 acts_upstream_of_or_within ISO MGI:2386445 (PMID:9356462) RGD PMID:9356462 NCBI chr10:53,393,901...53,525,174
Ensembl chr10:53,394,389...53,525,165 		JBrowse link
G Myl2 myosin light chain 2 acts_upstream_of_or_within ISO MGI:2385922 (PMID:9422794) RGD PMID:9422794 NCBI chr12:34,454,223...34,468,554
Ensembl chr12:34,454,218...34,468,983 		JBrowse link
G Mylk3 myosin light chain kinase 3 involved_in IMP
IBA		 PMID:17885681
GO_REF:0000033		 GO_Central PMID:17885681 GO_REF:0000033, RGD:8554371 NCBI chr19:21,685,085...21,743,587
Ensembl chr19:21,691,929...21,742,954 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in IEA
ISO
ISS		 GO_REF:0000107
UniProtKB:P05622 (MGI:1931346|PMID:11239463)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:11239463 GO_REF:0000024 GO_REF:0000107 MGI:1931346 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISS
ISO		 GO_REF:0000024
UniProtKB:P26618 (MGI:1931346|PMID:11239463)		 UniProt
RGD		 PMID:11239463 GO_REF:0000024 MGI:1931346 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO MGI:3522206|MGI:3522214 (PMID:15569937) RGD PMID:15569937 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733 		JBrowse link
G Tcap titin-cap involved_in ISO (PMID:9817758) RGD PMID:9817758 NCBI chr10:83,381,719...83,382,887
Ensembl chr10:83,381,719...83,382,887 		JBrowse link
G Ttn titin involved_in
acts_upstream_of_or_within		 ISO (PMID:11846417), (PMID:9817758)
MGI:3654306 (PMID:16702235)		 RGD PMID:9817758 PMID:11846417 PMID:16702235 NCBI chr 3:61,652,432...61,924,912
Ensembl chr 3:61,652,439...61,924,741 		JBrowse link
cardiac muscle thin filament assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neb nebulin involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:36,613,677...36,811,618
Ensembl chr 3:36,613,716...36,811,574 		JBrowse link
G Nebl nebulette involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:11822876), (PMID:18823973)		 UniProt
GO_Central
RGD		 PMID:11822876 PMID:18823973 GO_REF:0000024 GO_REF:0000033 NCBI chr17:80,113,891...80,466,331
Ensembl chr17:80,118,543...80,466,210 		JBrowse link
G Nrap nebulin-related anchoring protein involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:255,350,113...255,427,704
Ensembl chr 1:255,350,113...255,427,693 		JBrowse link
negative regulation of cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad4 SMAD family member 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3689643|PMID:16151019)		 Ensembl
RGD		 PMID:16151019 GO_REF:0000107 MGI:3689643 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
ventricular cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2a myocyte enhancer factor 2a involved_in IEA
ISO		 GO_REF:0000107
(MGI:2429350|PMID:12379849)		 Ensembl
RGD		 PMID:12379849 GO_REF:0000107 MGI:2429350 NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948 		JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3042511 (PMID:19546853)		 Ensembl
RGD		 PMID:19546853 GO_REF:0000107 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (MGI:3830437|PMID:19091769) RGD PMID:19091769 MGI:3830437 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    developmental process 7008
      anatomical structure formation involved in morphogenesis 1363
        cellular component assembly involved in morphogenesis 150
          myofibril assembly 79
            cardiac myofibril assembly 19
              atrial cardiac myofibril assembly 0
              cardiac muscle myosin thick filament assembly 0
              cardiac muscle thin filament assembly 3
              negative regulation of cardiac myofibril assembly 1
              positive regulation of cardiac myofibril assembly 0
              regulation of cardiac myofibril assembly + 1
              ventricular cardiac myofibril assembly 3
Path 2
Term Annotations click to browse term
  biological_process 20115
    developmental process 7008
      anatomical structure development 6530
        multicellular organism development 5268
          system development 4550
            circulatory system development 1373
              heart development 744
                cardiocyte differentiation 208
                  cardiac muscle cell differentiation 168
                    cardiac muscle cell development 120
                      cardiac myofibril assembly 19
                        atrial cardiac myofibril assembly 0
                        cardiac muscle myosin thick filament assembly 0
                        cardiac muscle thin filament assembly 3
                        negative regulation of cardiac myofibril assembly 1
                        positive regulation of cardiac myofibril assembly 0
                        regulation of cardiac myofibril assembly + 1
                        ventricular cardiac myofibril assembly 3
paths to the root