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ONTOLOGY REPORT - ANNOTATIONS

Term:alpha-beta T cell proliferation
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Accession:GO:0046633 term browser browse the term
Definition:The expansion of an alpha-beta T cell population by cell division.
Synonyms:exact_synonym: alpha-beta T lymphocyte proliferation

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alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase acts_upstream_of ISO (PMID:17210642) MGI PMID:17210642 NCBI chrNW_004955416:14,814,753...14,899,865
Ensembl chrNW_004955416:14,842,033...14,899,687 		JBrowse link
G Clec4g C-type lectin domain family 4 member G acts_upstream_of ISO (PMID:23487419) MGI PMID:23487419 NCBI chrNW_004955563:1,571,374...1,574,901
Ensembl chrNW_004955563:1,571,288...1,575,979 		JBrowse link
G Dock2 dedicator of cytokinesis 2 acts_upstream_of_or_within ISO (PMID:12871644) MGI PMID:12871644 NCBI chrNW_004955408:22,630,375...23,059,832
Ensembl chrNW_004955408:22,630,364...23,059,899 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of ISO (PMID:16945588) MGI PMID:16945588 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of ISO (PMID:7751624) MGI PMID:7751624 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552 		JBrowse link
activated CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf18 TNF superfamily member 18 NOT|involved_in ISO (MGI:5551556|PMID:24107315) UniProt PMID:24107315 MGI:5551556 NCBI chrNW_004955406:13,391,162...13,402,479 JBrowse link
CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card11 caspase recruitment domain family member 11 acts_upstream_of ISO (PMID:12867038) MGI PMID:12867038 NCBI chrNW_004955460:12,368,987...12,487,675
Ensembl chrNW_004955460:12,368,918...12,490,041 		JBrowse link
G Cblb Cbl proto-oncogene B acts_upstream_of ISO (PMID:14973438) MGI PMID:14973438 NCBI chrNW_004955427:6,601,651...6,812,896
Ensembl chrNW_004955427:6,604,820...6,812,882 		JBrowse link
G Cd24 CD24 molecule acts_upstream_of ISO (PMID:15314074)
(PMID:8125140)		 MGI PMID:8125140 PMID:15314074 NCBI chrNW_004955411:32,270,881...32,275,236
Ensembl chrNW_004955411:32,270,881...32,275,236 		JBrowse link
G Cd28 CD28 molecule acts_upstream_of ISO (PMID:14973438), (PMID:8125140), (PMID:9368605)
(PMID:9368605)		 MGI PMID:8125140 PMID:9368605 PMID:14973438 NCBI chrNW_004955457:11,159,769...11,253,099
Ensembl chrNW_004955457:11,162,282...11,192,991 		JBrowse link
G Cd3e CD3e molecule acts_upstream_of ISO (PMID:11894097), (PMID:14973438), (PMID:8125140) MGI PMID:8125140 PMID:11894097 PMID:14973438 NCBI chrNW_004955412:19,464,666...19,476,425
Ensembl chrNW_004955412:19,464,613...19,478,990 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of ISO (PMID:17028180) MGI PMID:17028180 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Itch itchy E3 ubiquitin protein ligase acts_upstream_of ISO (PMID:14973438) MGI PMID:14973438 NCBI chrNW_004955422:26,810,829...26,918,517
Ensembl chrNW_004955422:26,809,972...26,887,123 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of ISO (PMID:17137798) MGI PMID:17137798 NCBI chrNW_004955415:11,643,846...11,666,131
Ensembl chrNW_004955415:11,643,846...11,666,131 		JBrowse link
G Prkcq protein kinase C theta acts_upstream_of ISO (PMID:12867038) MGI PMID:12867038 NCBI chrNW_004955421:23,072,607...23,151,591
Ensembl chrNW_004955421:23,070,955...23,175,699 		JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of ISO (PMID:11894098)
(PMID:11894097)		 MGI PMID:11894097 PMID:11894098 NCBI chrNW_004955417:6,669,675...6,698,142
Ensembl chrNW_004955417:6,669,675...6,702,228 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 acts_upstream_of ISO (PMID:15568026) MGI PMID:15568026 NCBI chrNW_004955486:8,670,182...8,684,677 JBrowse link
negative regulation of alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btla B and T lymphocyte associated acts_upstream_of_or_within ISO (PMID:15568026) MGI PMID:15568026 NCBI chrNW_004955427:12,804,467...12,837,178
Ensembl chrNW_004955427:12,802,581...12,837,031 		JBrowse link
G Clec4g C-type lectin domain family 4 member G acts_upstream_of_or_within ISO (PMID:23487419) MGI PMID:23487419 NCBI chrNW_004955563:1,571,374...1,574,901
Ensembl chrNW_004955563:1,571,288...1,575,979 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:16945588) MGI PMID:16945588 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
negative regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 involved_in ISO (MGI:5908533|PMID:25009204) UniProt PMID:25009204 MGI:5908533 NCBI chrNW_004955466:2,549,557...2,577,060
Ensembl chrNW_004955466:2,549,557...2,577,060 		JBrowse link
G Cblb Cbl proto-oncogene B acts_upstream_of_or_within ISO (PMID:14973438) MGI PMID:14973438 NCBI chrNW_004955427:6,601,651...6,812,896
Ensembl chrNW_004955427:6,604,820...6,812,882 		JBrowse link
G Cd274 CD274 molecule involved_in ISO (PMID:24691993) UniProt PMID:24691993 NCBI chrNW_004955434:9,487,309...9,508,366
Ensembl chrNW_004955434:9,487,315...9,505,904 		JBrowse link
G Cd44 CD44 molecule (IN blood group) involved_in ISO (MGI:5688819|PMID:25065622) UniProt PMID:25065622 MGI:5688819 NCBI chrNW_004955422:11,106,061...11,189,951 JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:17028180) MGI PMID:17028180 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Itch itchy E3 ubiquitin protein ligase acts_upstream_of_or_within ISO (PMID:14973438) MGI PMID:14973438 NCBI chrNW_004955422:26,810,829...26,918,517
Ensembl chrNW_004955422:26,809,972...26,887,123 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:20209097)
(MGI:5688819|PMID:25065622)		 UniProt PMID:20209097 PMID:25065622 MGI:5688819 NCBI chrNW_004955481:5,234,125...5,249,564 JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO (PMID:17137798) MGI PMID:17137798 NCBI chrNW_004955415:11,643,846...11,666,131
Ensembl chrNW_004955415:11,643,846...11,666,131 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 acts_upstream_of_or_within ISO (PMID:15568026) MGI PMID:15568026 NCBI chrNW_004955486:8,670,182...8,684,677 JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 involved_in ISO (PMID:17164348) BHF-UCL PMID:17164348 NCBI chrNW_004955402:2,652,020...2,685,350
Ensembl chrNW_004955402:2,652,020...2,686,117 		JBrowse link
G Vsir V-set immunoregulatory receptor involved_in
acts_upstream_of_or_within		 ISO (PMID:24691993)
(PMID:21383057)		 UniProt
MGI		 PMID:21383057 PMID:24691993 NCBI chrNW_004955437:19,716,466...19,743,428 JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) BHF-UCL PMID:10887101 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
negative regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc4a2 solute carrier family 4 member 2 involved_in ISO (MGI:6840447|PMID:24515893) UniProt PMID:24515893 MGI:6840447 NCBI chrNW_004955491:5,498,472...5,513,389
Ensembl chrNW_004955491:5,499,033...5,517,319 		JBrowse link
G Vsir V-set immunoregulatory receptor involved_in ISO (PMID:24691993) UniProt PMID:24691993 NCBI chrNW_004955437:19,716,466...19,743,428 JBrowse link
negative regulation of NK T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zbtb7b zinc finger and BTB domain containing 7B involved_in ISO (MGI:5449456|PMID:23105140) UniProt PMID:23105140 MGI:5449456 NCBI chrNW_004955545:1,504,656...1,519,954
Ensembl chrNW_004955545:1,503,514...1,521,003 		JBrowse link
NK T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elf4 E74 like ETS transcription factor 4 involved_in ISO (MGI:2388503|PMID:12387738) UniProt PMID:12387738 MGI:2388503 NCBI chrNW_004955473:4,934,770...4,986,283
Ensembl chrNW_004955473:4,942,385...4,986,433 		JBrowse link
G Il15 interleukin 15 acts_upstream_of_or_within ISO (PMID:10704459) MGI PMID:10704459 NCBI chrNW_004955471:1,496,352...1,583,919
Ensembl chrNW_004955471:1,497,483...1,511,469 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:19423665) MGI PMID:19423665 NCBI chrNW_004955461:2,714,022...2,718,872
Ensembl chrNW_004955461:2,714,022...2,718,982 		JBrowse link
positive regulation of alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase acts_upstream_of_or_within ISO (PMID:17210642) MGI PMID:17210642 NCBI chrNW_004955416:14,814,753...14,899,865
Ensembl chrNW_004955416:14,842,033...14,899,687 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 involved_in ISO (MGI:3699670|PMID:14662900) BHF-UCL PMID:14662900 MGI:3699670 NCBI chrNW_004955420:25,641,184...25,664,413 JBrowse link
G Cd24 CD24 molecule acts_upstream_of_or_within ISO (PMID:1346270), (PMID:9368605)
(PMID:1385153), (PMID:7908303)
(PMID:9368605)		 MGI PMID:1346270 PMID:1385153 PMID:7908303 PMID:9368605 NCBI chrNW_004955411:32,270,881...32,275,236
Ensembl chrNW_004955411:32,270,881...32,275,236 		JBrowse link
G Cd80 CD80 molecule acts_upstream_of_or_within ISO (PMID:1385153) MGI PMID:1385153 NCBI chrNW_004955427:19,237,251...19,274,001
Ensembl chrNW_004955427:19,236,445...19,261,517 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:7751624) MGI PMID:7751624 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552 		JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within ISO (PMID:9275205) MGI PMID:9275205 NCBI chrNW_004955515:1,328,793...1,400,206
Ensembl chrNW_004955515:1,328,630...1,380,581 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3772919|PMID:16670306) BHF-UCL PMID:16670306 MGI:3772919 NCBI chrNW_004955406:13,477,077...13,493,309
Ensembl chrNW_004955406:13,477,077...13,493,309 		JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase 70kDa acts_upstream_of_or_within ISO (PMID:9275205) MGI PMID:9275205 NCBI chrNW_004955470:4,379,260...4,397,851
Ensembl chrNW_004955470:4,386,311...4,396,419 		JBrowse link
positive regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card11 caspase recruitment domain family member 11 acts_upstream_of_or_within ISO (PMID:12867038) MGI PMID:12867038 NCBI chrNW_004955460:12,368,987...12,487,675
Ensembl chrNW_004955460:12,368,918...12,490,041 		JBrowse link
G Cd24 CD24 molecule acts_upstream_of_or_within ISO (PMID:15314074)
(PMID:8125140)		 MGI PMID:8125140 PMID:15314074 NCBI chrNW_004955411:32,270,881...32,275,236
Ensembl chrNW_004955411:32,270,881...32,275,236 		JBrowse link
G Cd28 CD28 molecule acts_upstream_of_or_within ISO (PMID:14973438), (PMID:8125140), (PMID:9368605)
(PMID:9368605)		 MGI PMID:8125140 PMID:9368605 PMID:14973438 NCBI chrNW_004955457:11,159,769...11,253,099
Ensembl chrNW_004955457:11,162,282...11,192,991 		JBrowse link
G Cd3e CD3e molecule acts_upstream_of_or_within ISO (PMID:11894097), (PMID:14973438), (PMID:8125140) MGI PMID:8125140 PMID:11894097 PMID:14973438 NCBI chrNW_004955412:19,464,666...19,476,425
Ensembl chrNW_004955412:19,464,613...19,478,990 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:16818763) UniProt PMID:16818763 NCBI chrNW_004955406:42,773,368...42,796,205 JBrowse link
G Cd81 CD81 molecule involved_in ISO (PMID:22307619) UniProt PMID:22307619 NCBI chrNW_004955422:14,155,682...14,175,181
Ensembl chrNW_004955422:14,155,682...14,175,181 		JBrowse link
G Irgm immunity related GTPase M involved_in ISO (MGI:3822251|PMID:18806793) UniProt PMID:18806793 MGI:3822251 NCBI chrNW_004955408:2,338,510...2,344,566 JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:16116184) UniProt PMID:16116184 NCBI chrNW_004955481:5,234,125...5,249,564 JBrowse link
G Prkcq protein kinase C theta acts_upstream_of_or_within ISO (PMID:12867038) MGI PMID:12867038 NCBI chrNW_004955421:23,072,607...23,151,591
Ensembl chrNW_004955421:23,070,955...23,175,699 		JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO (PMID:11894097)
(PMID:11894098)		 MGI PMID:11894097 PMID:11894098 NCBI chrNW_004955417:6,669,675...6,698,142
Ensembl chrNW_004955417:6,669,675...6,702,228 		JBrowse link
G Tgfbr2 transforming growth factor beta receptor 2 involved_in ISO (PMID:17164348) BHF-UCL PMID:17164348 NCBI chrNW_004955430:21,919,338...21,999,688
Ensembl chrNW_004955430:21,932,553...22,001,837 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (MGI:5009207|PMID:9973465) BHF-UCL PMID:9973465 MGI:5009207 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
positive regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd244 CD244 molecule involved_in ISO (MGI:5700312|PMID:11739483) UniProt PMID:11739483 MGI:5700312 NCBI chrNW_004955468:12,532,937...12,559,859
Ensembl chrNW_004955468:12,534,064...12,559,434 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (MGI:5562517|PMID:23871208) UniProt PMID:23871208 MGI:5562517 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) BHF-UCL PMID:10887101 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
positive regulation of NK T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il12b interleukin 12B involved_in ISO (PMID:19088061) ComplexPortal PMID:19088061 NCBI chrNW_004955408:13,302,506...13,316,300
Ensembl chrNW_004955408:13,304,219...13,312,620 		JBrowse link
G Il18 interleukin 18 involved_in ISO (PMID:19088061) BHF-UCL PMID:19088061 NCBI chrNW_004955412:13,807,361...13,826,007
Ensembl chrNW_004955412:13,806,553...13,825,634 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:19088061) ComplexPortal PMID:19088061 NCBI chrNW_004955458:3,946,964...3,949,180
Ensembl chrNW_004955458:3,947,803...3,949,312 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISO (PMID:19088061) ComplexPortal PMID:19088061 NCBI chrNW_004955434:9,227,897...9,341,208
Ensembl chrNW_004955434:9,227,595...9,341,208 		JBrowse link
G Rasal3 RAS protein activator like 3 involved_in ISO (PMID:25652366) UniProt PMID:25652366 NCBI chrNW_004955495:7,795,619...7,808,674
Ensembl chrNW_004955495:7,795,842...7,808,511 		JBrowse link
G Tyk2 tyrosine kinase 2 involved_in ISO (PMID:19088061) ComplexPortal PMID:19088061 NCBI chrNW_004955495:1,618,099...1,637,996
Ensembl chrNW_004955495:1,617,999...1,636,068 		JBrowse link
regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il2 interleukin 2 acts_upstream_of_or_within ISO (PMID:16227984) MGI PMID:16227984 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha acts_upstream_of_or_within ISO (PMID:16227984) MGI PMID:16227984 NCBI chrNW_004955421:22,642,004...22,694,729
Ensembl chrNW_004955421:22,641,511...22,694,913 		JBrowse link
regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf1 interferon regulatory factor 1 involved_in ISO (MGI:5317515|PMID:21909274) UniProt PMID:21909274 MGI:5317515 NCBI chrNW_004955408:3,882,282...3,887,965
Ensembl chrNW_004955408:3,880,155...3,887,973 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 involved_in ISO (MGI:5546548|PMID:23963642) UniProt PMID:23963642 MGI:5546548 NCBI chrNW_004955422:2,064,010...2,081,681
Ensembl chrNW_004955422:2,061,851...2,082,514 		JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 involved_in ISO (MGI:5546548|PMID:23963642) UniProt PMID:23963642 MGI:5546548 NCBI chrNW_004955403:36,989,509...37,141,188
Ensembl chrNW_004955403:36,988,811...37,142,401 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12362
    immune system process 1980
      leukocyte activation 888
        lymphocyte activation 720
          T cell activation 507
            T cell proliferation 226
              alpha-beta T cell proliferation 51
                CD4-positive, alpha-beta T cell proliferation + 25
                CD8-positive, alpha-beta T cell proliferation + 8
                NK T cell proliferation + 10
                alpha-beta T cell proliferation involved in immune response + 0
                negative regulation of alpha-beta T cell proliferation + 16
                positive regulation of alpha-beta T cell proliferation + 27
                regulation of alpha-beta T cell proliferation + 46
Path 2
Term Annotations click to browse term
  biological_process 12362
    cellular process 11484
      cell activation 1018
        leukocyte activation 888
          lymphocyte activation 720
            T cell activation 507
              T cell proliferation 226
                alpha-beta T cell proliferation 51
                  CD4-positive, alpha-beta T cell proliferation + 25
                  CD8-positive, alpha-beta T cell proliferation + 8
                  NK T cell proliferation + 10
                  alpha-beta T cell proliferation involved in immune response + 0
                  negative regulation of alpha-beta T cell proliferation + 16
                  positive regulation of alpha-beta T cell proliferation + 27
                  regulation of alpha-beta T cell proliferation + 46
paths to the root