Tyk2 (tyrosine kinase 2) - Rat Genome Database

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Gene: Tyk2 (tyrosine kinase 2) Chinchilla lanigera
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Symbol: Tyk2
Name: tyrosine kinase 2
RGD ID: 8761052
Description: ENCODES a protein that exhibits growth hormone receptor binding (ortholog); protein tyrosine kinase activity (ortholog); type 1 angiotensin receptor binding (ortholog); PARTICIPATES IN angiotensin II signaling pathway via AT1 receptor; Interleukin-10 signaling pathway; interleukin-12 signaling pathway; ASSOCIATED WITH autistic disorder (ortholog); Cocaine-Related Disorders (ortholog); Crohn's disease (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: non-receptor tyrosine-protein kinase TYK2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554951,617,999 - 1,636,068 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554951,618,099 - 1,637,996 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
nucleus  (ISO)

Molecular Function

References


Genomics

Comparative Map Data
Tyk2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554951,617,999 - 1,636,068 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554951,618,099 - 1,637,996 (-)NCBIChiLan1.0ChiLan1.0
TYK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1910,350,529 - 10,380,572 (-)EnsemblGRCh38hg38GRCh38
GRCh381910,350,528 - 10,380,572 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371910,461,209 - 10,491,248 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,322,209 - 10,352,211 (-)NCBINCBI36hg18NCBI36
Build 341910,322,208 - 10,352,211NCBI
Celera1910,356,496 - 10,385,954 (-)NCBI
Cytogenetic Map19p13.2NCBI
HuRef1910,041,213 - 10,071,290 (-)NCBIHuRef
CHM1_11910,461,760 - 10,491,969 (-)NCBICHM1_1
Tyk2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39921,015,364 - 21,042,689 (-)NCBIGRCm39mm39
GRCm39 Ensembl921,015,364 - 21,042,539 (-)Ensembl
GRCm38921,104,068 - 21,131,393 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl921,104,068 - 21,131,243 (-)EnsemblGRCm38mm10GRCm38
MGSCv37920,908,512 - 20,935,719 (-)NCBIGRCm37mm9NCBIm37
MGSCv36920,854,476 - 20,881,612 (-)NCBImm8
Celera918,372,782 - 18,399,989 (-)NCBICelera
Cytogenetic Map9A3NCBI
Tyk2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2819,641,881 - 19,667,157 (-)NCBI
Rnor_6.0 Ensembl822,124,560 - 22,150,005 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0822,118,224 - 22,149,807 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0822,180,760 - 22,205,979 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4820,096,969 - 20,149,004 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1820,128,873 - 20,148,992 (-)NCBI
Celera821,036,299 - 21,057,402 (-)NCBICelera
Cytogenetic Map8q13NCBI
TYK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11910,565,490 - 10,596,647 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1910,565,490 - 10,594,541 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0199,901,612 - 9,932,623 (-)NCBIMhudiblu_PPA_v0panPan3
TYK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12050,747,145 - 50,770,008 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2050,748,329 - 50,769,216 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2050,617,718 - 50,639,776 (+)NCBI
ROS_Cfam_1.02051,269,592 - 51,291,659 (+)NCBI
UMICH_Zoey_3.12050,475,504 - 50,497,770 (+)NCBI
UNSW_CanFamBas_1.02050,904,500 - 50,926,568 (+)NCBI
UU_Cfam_GSD_1.02051,145,386 - 51,167,670 (+)NCBI
Tyk2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118209,650,169 - 209,673,217 (+)NCBI
SpeTri2.0NW_004936659681,463 - 704,484 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TYK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl269,157,799 - 69,183,461 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1269,157,774 - 69,183,555 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2269,492,135 - 69,517,888 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TYK2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.169,399,945 - 9,420,054 (-)NCBI
ChlSab1.1 Ensembl69,399,775 - 9,417,630 (-)Ensembl
Tyk2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248282,499,811 - 2,518,817 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000019747   ⟹   ENSCLAP00000019554
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554951,617,999 - 1,636,068 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000019748   ⟹   ENSCLAP00000019555
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554951,617,999 - 1,636,068 (-)Ensembl
RefSeq Acc Id: XM_005405593   ⟹   XP_005405650
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554951,618,099 - 1,636,993 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013505151   ⟹   XP_013360605
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554951,619,956 - 1,636,993 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013505152   ⟹   XP_013360606
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554951,619,956 - 1,637,820 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013505153   ⟹   XP_013360607
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554951,619,956 - 1,637,996 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013505154   ⟹   XP_013360608
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554951,619,956 - 1,636,718 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013505155   ⟹   XP_013360609
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554951,619,956 - 1,636,987 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013505156   ⟹   XP_013360610
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554951,619,956 - 1,635,550 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013505157   ⟹   XP_013360611
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554951,619,956 - 1,636,993 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013505158   ⟹   XP_013360612
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554951,619,956 - 1,637,017 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013505159   ⟹   XP_013360613
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554951,619,924 - 1,636,993 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_005405650   ⟸   XM_005405593
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013360613   ⟸   XM_013505159
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_013360607   ⟸   XM_013505153
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013360606   ⟸   XM_013505152
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013360612   ⟸   XM_013505158
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_013360611   ⟸   XM_013505157
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013360605   ⟸   XM_013505151
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013360609   ⟸   XM_013505155
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013360608   ⟸   XM_013505154
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013360610   ⟸   XM_013505156
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCLAP00000019555   ⟸   ENSCLAT00000019748
RefSeq Acc Id: ENSCLAP00000019554   ⟸   ENSCLAT00000019747


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000013417 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000019555 ENTREZGENE
Ensembl Transcript ENSCLAT00000019748 ENTREZGENE
NCBI Gene Tyk2 ENTREZGENE