ONTOLOGY REPORT - ANNOTATIONS |
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Term: | CD4-positive, alpha-beta T cell proliferation |
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Accession: | GO:0035739
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browse the term
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Definition: | The expansion of a CD4-positive, alpha-beta T cell population by cell division. |
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Card11 |
caspase recruitment domain family member 11 |
acts_upstream_of |
ISO |
(PMID:12867038) |
MGI |
PMID:12867038 |
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NCBI chrNW_004955460:12,368,987...12,487,675
Ensembl chrNW_004955460:12,368,918...12,490,041
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Cblb |
Cbl proto-oncogene B |
acts_upstream_of |
ISO |
(PMID:14973438) |
MGI |
PMID:14973438 |
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NCBI chrNW_004955427:6,601,651...6,812,896
Ensembl chrNW_004955427:6,604,820...6,812,882
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Cd24 |
CD24 molecule |
acts_upstream_of |
ISO |
(PMID:15314074) (PMID:8125140) |
MGI |
PMID:8125140 PMID:15314074 |
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NCBI chrNW_004955411:32,270,881...32,275,236
Ensembl chrNW_004955411:32,270,881...32,275,236
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Cd28 |
CD28 molecule |
acts_upstream_of |
ISO |
(PMID:14973438), (PMID:8125140), (PMID:9368605) (PMID:9368605) |
MGI |
PMID:8125140 PMID:9368605 PMID:14973438 |
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NCBI chrNW_004955457:11,159,769...11,253,099
Ensembl chrNW_004955457:11,162,282...11,192,991
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Cd3e |
CD3e molecule |
acts_upstream_of |
ISO |
(PMID:11894097), (PMID:14973438), (PMID:8125140) |
MGI |
PMID:8125140 PMID:11894097 PMID:14973438 |
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NCBI chrNW_004955412:19,464,666...19,476,425
Ensembl chrNW_004955412:19,464,613...19,478,990
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Foxp3 |
forkhead box P3 |
acts_upstream_of |
ISO |
(PMID:17028180) |
MGI |
PMID:17028180 |
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NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606
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Itch |
itchy E3 ubiquitin protein ligase |
acts_upstream_of |
ISO |
(PMID:14973438) |
MGI |
PMID:14973438 |
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NCBI chrNW_004955422:26,810,829...26,918,517
Ensembl chrNW_004955422:26,809,972...26,887,123
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Ndfip1 |
Nedd4 family interacting protein 1 |
acts_upstream_of |
ISO |
(PMID:17137798) |
MGI |
PMID:17137798 |
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NCBI chrNW_004955415:11,643,846...11,666,131
Ensembl chrNW_004955415:11,643,846...11,666,131
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Prkcq |
protein kinase C theta |
acts_upstream_of |
ISO |
(PMID:12867038) |
MGI |
PMID:12867038 |
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NCBI chrNW_004955421:23,072,607...23,151,591
Ensembl chrNW_004955421:23,070,955...23,175,699
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Ripk2 |
receptor interacting serine/threonine kinase 2 |
acts_upstream_of |
ISO |
(PMID:11894098) (PMID:11894097) |
MGI |
PMID:11894097 PMID:11894098 |
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NCBI chrNW_004955417:6,669,675...6,698,142
Ensembl chrNW_004955417:6,669,675...6,702,228
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Tnfrsf14 |
TNF receptor superfamily member 14 |
acts_upstream_of |
ISO |
(PMID:15568026) |
MGI |
PMID:15568026 |
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NCBI chrNW_004955486:8,670,182...8,684,677
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Tnfsf18 |
TNF superfamily member 18 |
NOT|involved_in |
ISO |
(MGI:5551556|PMID:24107315) |
UniProt |
PMID:24107315 |
MGI:5551556 |
NCBI chrNW_004955406:13,391,162...13,402,479
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Arg2 |
arginase 2 |
involved_in |
ISO |
(MGI:5908533|PMID:25009204) |
UniProt |
PMID:25009204 |
MGI:5908533 |
NCBI chrNW_004955466:2,549,557...2,577,060
Ensembl chrNW_004955466:2,549,557...2,577,060
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Cblb |
Cbl proto-oncogene B |
acts_upstream_of_or_within |
ISO |
(PMID:14973438) |
MGI |
PMID:14973438 |
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NCBI chrNW_004955427:6,601,651...6,812,896
Ensembl chrNW_004955427:6,604,820...6,812,882
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Cd274 |
CD274 molecule |
involved_in |
ISO |
(PMID:24691993) |
UniProt |
PMID:24691993 |
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NCBI chrNW_004955434:9,487,309...9,508,366
Ensembl chrNW_004955434:9,487,315...9,505,904
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Cd44 |
CD44 molecule (IN blood group) |
involved_in |
ISO |
(MGI:5688819|PMID:25065622) |
UniProt |
PMID:25065622 |
MGI:5688819 |
NCBI chrNW_004955422:11,106,061...11,189,951
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Foxp3 |
forkhead box P3 |
acts_upstream_of_or_within |
ISO |
(PMID:17028180) |
MGI |
PMID:17028180 |
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NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606
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Itch |
itchy E3 ubiquitin protein ligase |
acts_upstream_of_or_within |
ISO |
(PMID:14973438) |
MGI |
PMID:14973438 |
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NCBI chrNW_004955422:26,810,829...26,918,517
Ensembl chrNW_004955422:26,809,972...26,887,123
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Lgals9 |
galectin 9 |
involved_in |
ISO |
(PMID:20209097) (MGI:5688819|PMID:25065622) |
UniProt |
PMID:20209097 PMID:25065622 |
MGI:5688819 |
NCBI chrNW_004955481:5,234,125...5,249,564
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Ndfip1 |
Nedd4 family interacting protein 1 |
acts_upstream_of_or_within |
ISO |
(PMID:17137798) |
MGI |
PMID:17137798 |
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NCBI chrNW_004955415:11,643,846...11,666,131
Ensembl chrNW_004955415:11,643,846...11,666,131
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Tnfrsf14 |
TNF receptor superfamily member 14 |
acts_upstream_of_or_within |
ISO |
(PMID:15568026) |
MGI |
PMID:15568026 |
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NCBI chrNW_004955486:8,670,182...8,684,677
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Twsg1 |
twisted gastrulation BMP signaling modulator 1 |
involved_in |
ISO |
(PMID:17164348) |
BHF-UCL |
PMID:17164348 |
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NCBI chrNW_004955402:2,652,020...2,685,350
Ensembl chrNW_004955402:2,652,020...2,686,117
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Vsir |
V-set immunoregulatory receptor |
involved_in acts_upstream_of_or_within |
ISO |
(PMID:24691993) (PMID:21383057) |
UniProt MGI |
PMID:21383057 PMID:24691993 |
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NCBI chrNW_004955437:19,716,466...19,743,428
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Xcl1 |
X-C motif chemokine ligand 1 |
involved_in |
ISO |
(PMID:10887101) |
BHF-UCL |
PMID:10887101 |
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NCBI chrNW_004955462:8,594,416...8,598,101
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Card11 |
caspase recruitment domain family member 11 |
acts_upstream_of_or_within |
ISO |
(PMID:12867038) |
MGI |
PMID:12867038 |
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NCBI chrNW_004955460:12,368,987...12,487,675
Ensembl chrNW_004955460:12,368,918...12,490,041
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G |
Cd24 |
CD24 molecule |
acts_upstream_of_or_within |
ISO |
(PMID:15314074) (PMID:8125140) |
MGI |
PMID:8125140 PMID:15314074 |
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NCBI chrNW_004955411:32,270,881...32,275,236
Ensembl chrNW_004955411:32,270,881...32,275,236
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Cd28 |
CD28 molecule |
acts_upstream_of_or_within |
ISO |
(PMID:14973438), (PMID:8125140), (PMID:9368605) (PMID:9368605) |
MGI |
PMID:8125140 PMID:9368605 PMID:14973438 |
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NCBI chrNW_004955457:11,159,769...11,253,099
Ensembl chrNW_004955457:11,162,282...11,192,991
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Cd3e |
CD3e molecule |
acts_upstream_of_or_within |
ISO |
(PMID:11894097), (PMID:14973438), (PMID:8125140) |
MGI |
PMID:8125140 PMID:11894097 PMID:14973438 |
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NCBI chrNW_004955412:19,464,666...19,476,425
Ensembl chrNW_004955412:19,464,613...19,478,990
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Cd55 |
CD55 molecule (Cromer blood group) |
involved_in |
ISO |
(PMID:16818763) |
UniProt |
PMID:16818763 |
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NCBI chrNW_004955406:42,773,368...42,796,205
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Cd81 |
CD81 molecule |
involved_in |
ISO |
(PMID:22307619) |
UniProt |
PMID:22307619 |
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NCBI chrNW_004955422:14,155,682...14,175,181
Ensembl chrNW_004955422:14,155,682...14,175,181
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Irgm |
immunity related GTPase M |
involved_in |
ISO |
(MGI:3822251|PMID:18806793) |
UniProt |
PMID:18806793 |
MGI:3822251 |
NCBI chrNW_004955408:2,338,510...2,344,566
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Lgals9 |
galectin 9 |
involved_in |
ISO |
(PMID:16116184) |
UniProt |
PMID:16116184 |
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NCBI chrNW_004955481:5,234,125...5,249,564
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Prkcq |
protein kinase C theta |
acts_upstream_of_or_within |
ISO |
(PMID:12867038) |
MGI |
PMID:12867038 |
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NCBI chrNW_004955421:23,072,607...23,151,591
Ensembl chrNW_004955421:23,070,955...23,175,699
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G |
Ripk2 |
receptor interacting serine/threonine kinase 2 |
acts_upstream_of_or_within |
ISO |
(PMID:11894097) (PMID:11894098) |
MGI |
PMID:11894097 PMID:11894098 |
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NCBI chrNW_004955417:6,669,675...6,698,142
Ensembl chrNW_004955417:6,669,675...6,702,228
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Tgfbr2 |
transforming growth factor beta receptor 2 |
involved_in |
ISO |
(PMID:17164348) |
BHF-UCL |
PMID:17164348 |
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NCBI chrNW_004955430:21,919,338...21,999,688
Ensembl chrNW_004955430:21,932,553...22,001,837
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Xcl1 |
X-C motif chemokine ligand 1 |
involved_in |
ISO |
(MGI:5009207|PMID:9973465) |
BHF-UCL |
PMID:9973465 |
MGI:5009207 |
NCBI chrNW_004955462:8,594,416...8,598,101
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Il2 |
interleukin 2 |
acts_upstream_of_or_within |
ISO |
(PMID:16227984) |
MGI |
PMID:16227984 |
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NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265
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Il2ra |
interleukin 2 receptor subunit alpha |
acts_upstream_of_or_within |
ISO |
(PMID:16227984) |
MGI |
PMID:16227984 |
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NCBI chrNW_004955421:22,642,004...22,694,729
Ensembl chrNW_004955421:22,641,511...22,694,913
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Term paths to the root
Path 1 |
biological_process |
12352 |
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immune system process |
1980 |
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leukocyte activation |
888 |
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lymphocyte activation |
720 |
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T cell activation |
507 |
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alpha-beta T cell activation |
177 |
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CD4-positive, alpha-beta T cell activation |
118 |
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CD4-positive, alpha-beta T cell proliferation |
25 |
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activated CD4-positive, alpha-beta T cell proliferation |
1 |
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negative regulation of CD4-positive, alpha-beta T cell proliferation |
12 |
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positive regulation of CD4-positive, alpha-beta T cell proliferation |
12 |
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regulation of CD4-positive, alpha-beta T cell proliferation + |
24 |
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Path 2 |
biological_process |
12352 |
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cellular process |
11484 |
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cell activation |
1018 |
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leukocyte activation |
888 |
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lymphocyte activation |
720 |
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T cell activation |
507 |
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alpha-beta T cell activation |
177 |
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CD4-positive, alpha-beta T cell activation |
118 |
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CD4-positive, alpha-beta T cell proliferation |
25 |
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activated CD4-positive, alpha-beta T cell proliferation |
1 |
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negative regulation of CD4-positive, alpha-beta T cell proliferation |
12 |
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positive regulation of CD4-positive, alpha-beta T cell proliferation |
12 |
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regulation of CD4-positive, alpha-beta T cell proliferation + |
24 |
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