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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of alpha-beta T cell proliferation
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Accession:GO:0046640 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of alpha-beta T cell proliferation.
Synonyms:exact_synonym: regulation of alpha-beta T lymphocyte proliferation


show annotations for term's descendants           Sort by:
negative regulation of alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btla B and T lymphocyte associated acts_upstream_of_or_within ISO MGI:3027713 (PMID:15568026) RGD PMID:15568026 NCBI chr11:55,563,683...55,588,187
Ensembl chr11:55,564,899...55,587,181 		JBrowse link
G Clec4g C-type lectin domain family 4, member G acts_upstream_of_or_within ISO MGI:5510586 (PMID:23487419) RGD PMID:23487419 NCBI chr12:1,780,370...1,785,027
Ensembl chr12:1,780,371...1,784,985 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:1857034 (PMID:16945588) RGD PMID:16945588 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703 		JBrowse link
negative regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5908533|PMID:25009204)		 Ensembl
RGD		 PMID:25009204 GO_REF:0000107 MGI:5908533 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
G Cblb Cbl proto-oncogene B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2180572 (PMID:14973438)		 Ensembl
RGD		 PMID:14973438 GO_REF:0000107 NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839 		JBrowse link
G Cd274 CD274 molecule involved_in ISO (PMID:24691993) RGD PMID:24691993 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cd44 CD44 molecule involved_in ISO (MGI:5688819|PMID:25065622) RGD PMID:25065622 MGI:5688819 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:17028180) RGD PMID:17028180 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Itch itchy E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:1856404 (PMID:14973438) RGD PMID:14973438 NCBI chr 3:143,642,348...143,733,745
Ensembl chr 3:143,645,637...143,733,543 		JBrowse link
G Lgals12 galectin 12 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 1:204,832,065...204,842,759
Ensembl chr 1:204,832,065...204,842,759 		JBrowse link
G Lgals5 galectin 5 involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr10:63,853,949...63,857,198
Ensembl chr10:63,853,935...63,857,153 		JBrowse link
G Lgals9 galectin 9 involved_in ISO
IBA
IEA		 (PMID:20209097)
GO_REF:0000033
GO_REF:0000118
(MGI:5688819|PMID:25065622)		 RGD
GO_Central
TreeGrafter		 PMID:20209097 PMID:25065622 GO_REF:0000033 GO_REF:0000118 MGI:5688819 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3695433 (PMID:17137798)		 Ensembl
RGD		 PMID:17137798 GO_REF:0000107 NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311 		JBrowse link
G Tarm1 T cell-interacting, activating receptor on myeloid cells 1 involved_in ISO (MGI:5908526|PMID:26311901) RGD PMID:26311901 MGI:5908526 NCBI chr 1:65,666,742...65,682,402
Ensembl chr 1:65,671,902...65,679,626 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 acts_upstream_of_or_within ISO (PMID:15568026) RGD PMID:15568026 NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703 		JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 involved_in ISO (PMID:17164348) RGD PMID:17164348 NCBI chr 9:105,533,116...105,567,460
Ensembl chr 9:105,533,136...105,567,479 		JBrowse link
G Vsir V-set immunoregulatory receptor involved_in
acts_upstream_of_or_within		 ISO (PMID:24691993)
(PMID:21383057)		 RGD PMID:21383057 PMID:24691993 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) RGD PMID:10887101 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
negative regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc4a2 solute carrier family 4 member 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6840447|PMID:24515893)		 UniProt
RGD		 PMID:24515893 GO_REF:0000024 MGI:6840447 NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965 		JBrowse link
G Vsir V-set immunoregulatory receptor involved_in ISO (PMID:24691993) RGD PMID:24691993 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878 		JBrowse link
negative regulation of NK T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zbtb7b zinc finger and BTB domain containing 7B involved_in ISO (MGI:5449456|PMID:23105140) RGD PMID:23105140 MGI:5449456 NCBI chr 2:174,795,831...174,811,980
Ensembl chr 2:174,797,453...174,814,236 		JBrowse link
positive regulation of alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase acts_upstream_of_or_within ISO MGI:3053044|MGI:3663359 (PMID:17210642) RGD PMID:17210642 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3699670|PMID:14662900)		 BHF-UCL
RGD		 PMID:14662900 GO_REF:0000024 MGI:3699670 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Cd24 CD24 molecule acts_upstream_of_or_within ISO MGI:2179996 (PMID:1346270), (PMID:1385153), (PMID:7908303), (PMID:9368605) RGD PMID:1346270 PMID:1385153 PMID:7908303 PMID:9368605 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Cd80 Cd80 molecule acts_upstream_of_or_within ISO (PMID:1385153) RGD PMID:1385153 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:2181288 (PMID:7751624) RGD PMID:7751624 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:99613 (PMID:9275205)
GO_REF:0000033
GO_REF:0000118		 Ensembl
RGD
GO_Central
TreeGrafter		 PMID:9275205 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3772919|PMID:16670306) RGD PMID:16670306 MGI:3772919 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 acts_upstream_of_or_within ISO MGI:99515 (PMID:9275205) RGD PMID:9275205 NCBI chr 9:38,989,750...39,011,701
Ensembl chr 9:38,989,750...39,011,700 		JBrowse link
positive regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card11 caspase recruitment domain family, member 11 acts_upstream_of_or_within ISO MGI:3039682 (PMID:12867038) RGD PMID:12867038 NCBI chr12:13,621,140...13,758,115
Ensembl chr12:13,621,087...13,758,112 		JBrowse link
G Cd24 CD24 molecule acts_upstream_of_or_within ISO MGI:2179996 (PMID:15314074), (PMID:8125140) RGD PMID:8125140 PMID:15314074 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Cd28 Cd28 molecule acts_upstream_of_or_within ISO MGI:1857150 (PMID:14973438), (PMID:8125140), (PMID:9368605) RGD PMID:8125140 PMID:9368605 PMID:14973438 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685 		JBrowse link
G Cd3e CD3 epsilon subunit of T-cell receptor complex acts_upstream_of_or_within ISO (PMID:11894097), (PMID:14973438), (PMID:8125140) RGD PMID:8125140 PMID:11894097 PMID:14973438 NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:16818763) RGD PMID:16818763 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831 		JBrowse link
G Cd81 Cd81 molecule involved_in ISO
ISS
IEA		 (PMID:22307619)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:22307619 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660 		JBrowse link
G Irgm immunity-related GTPase M involved_in ISS
ISO		 GO_REF:0000024
(MGI:3822251|PMID:18806793)		 UniProt
RGD		 PMID:18806793 GO_REF:0000024 MGI:3822251 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:16116184) RGD PMID:16116184 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Prkcq protein kinase C, theta involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2664379 (PMID:12867038)		 Ensembl
RGD		 PMID:12867038 GO_REF:0000107 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO MGI:2446070|MGI:2660793 (PMID:11894097), (PMID:11894098) RGD PMID:11894097 PMID:11894098 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO
IEA		 (PMID:17164348)
GO_REF:0000107		 RGD
Ensembl		 PMID:17164348 GO_REF:0000107 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5009207|PMID:9973465)		 Ensembl
RGD		 PMID:9973465 GO_REF:0000107 MGI:5009207 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
positive regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd244 CD244 molecule involved_in ISO (MGI:5700312|PMID:11739483) RGD PMID:11739483 MGI:5700312 NCBI chr13:84,051,339...84,082,864
Ensembl chr13:84,052,493...84,074,492 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (MGI:5562517|PMID:23871208) RGD PMID:23871208 MGI:5562517 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:25631937) RGD PMID:25631937 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE16 RT1 class I, locus CE16 involved_in ISO (PMID:25631937) RGD PMID:25631937 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) RGD PMID:10887101 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
positive regulation of NK T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il12b interleukin 12B involved_in ISO (PMID:19088061) RGD PMID:19088061 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il18 interleukin 18 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19088061)		 Ensembl
RGD		 PMID:19088061 GO_REF:0000107 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:19088061) RGD PMID:19088061 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISO (PMID:19088061) RGD PMID:19088061 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Rasal3 RAS protein activator like 3 involved_in ISO (PMID:25652366) RGD PMID:25652366 NCBI chr 7:11,396,554...11,411,347
Ensembl chr 7:11,396,090...11,411,465 		JBrowse link
G Tyk2 tyrosine kinase 2 involved_in ISO (PMID:19088061) RGD PMID:19088061 NCBI chr 8:19,641,881...19,667,157
Ensembl chr 8:19,641,884...19,667,044 		JBrowse link
regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il2 interleukin 2 acts_upstream_of_or_within ISO MGI:1857191 (PMID:16227984) RGD PMID:16227984 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha acts_upstream_of_or_within ISO MGI:1857192 (PMID:16227984) RGD PMID:16227984 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697 		JBrowse link
regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf1 interferon regulatory factor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5317515|PMID:21909274)		 UniProt
RGD		 PMID:21909274 GO_REF:0000024 MGI:5317515 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5546548|PMID:23963642)		 UniProt
Ensembl
RGD		 PMID:23963642 GO_REF:0000024 GO_REF:0000107 MGI:5546548 NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884 		JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5546548|PMID:23963642)		 UniProt
RGD		 PMID:23963642 GO_REF:0000024 MGI:5546548 NCBI chr16:28,735,522...28,901,261
Ensembl chr16:28,735,440...28,901,644 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    immune system process 3017
      leukocyte activation 1052
        lymphocyte activation 851
          T cell activation 601
            T cell proliferation 250
              regulation of T cell proliferation 203
                regulation of alpha-beta T cell proliferation 51
                  negative regulation of alpha-beta T cell proliferation + 19
                  positive regulation of alpha-beta T cell proliferation + 29
                  regulation of CD4-positive, alpha-beta T cell proliferation + 27
                  regulation of CD8-positive, alpha-beta T cell proliferation + 10
                  regulation of NK T cell proliferation + 7
Path 2
Term Annotations click to browse term
  biological_process 20413
    biological regulation 13755
      regulation of biological process 13322
        regulation of cellular process 12748
          regulation of cell population proliferation 1935
            regulation of leukocyte proliferation 290
              regulation of mononuclear cell proliferation 269
                regulation of lymphocyte proliferation 264
                  regulation of T cell proliferation 203
                    regulation of alpha-beta T cell proliferation 51
                      negative regulation of alpha-beta T cell proliferation + 19
                      positive regulation of alpha-beta T cell proliferation + 29
                      regulation of CD4-positive, alpha-beta T cell proliferation + 27
                      regulation of CD8-positive, alpha-beta T cell proliferation + 10
                      regulation of NK T cell proliferation + 7
paths to the root