Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of mast cell degranulation
go back to main search page
Accession:GO:0043306 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of mast cell degranulation.
Synonyms:exact_synonym: positive regulation of mast cell granule exocytosis;   up regulation of mast cell degranulation;   upregulation of mast cell degranulation
 narrow_synonym: activation of mast cell degranulation;   stimulation of mast cell degranulation


show annotations for term's descendants           Sort by:
positive regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11454903) Ensembl
MGI		 PMID:11454903 GO_REF:0000107 NCBI chr17:15,850,362...15,975,746
Ensembl chr17:15,945,130...15,975,746 		JBrowse link
G ADORA3 adenosine A3 receptor acts_upstream_of_or_within ISO (PMID:12817016) MGI PMID:12817016 NCBI chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633 		JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO RGD PMID:18209484 RGD:5130941 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,277...45,835,828 		JBrowse link
G FCER1A Fc epsilon receptor Ia acts_upstream_of_or_within ISO (PMID:9000133) MGI PMID:9000133 NCBI chr 1:159,283,575...159,308,202
Ensembl chr 1:159,289,714...159,308,224 		JBrowse link
G FCER1G Fc epsilon receptor Ig acts_upstream_of_or_within ISO (PMID:14764707) MGI PMID:14764707 NCBI chr 1:161,215,295...161,219,245
Ensembl chr 1:161,215,234...161,220,699 		JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:27,612,064...27,635,185
Ensembl chr 1:27,612,064...27,635,185 		JBrowse link
G GAB2 GRB2 associated binding protein 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr11:78,215,293...78,417,820
Ensembl chr11:78,215,293...78,418,348 		JBrowse link
G GATA1 GATA binding protein 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:22390417 GO_REF:0000107 RGD:9587812 NCBI chr  X:48,786,590...48,794,311
Ensembl chr  X:48,786,540...48,794,311 		JBrowse link
G GATA2 GATA binding protein 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:22390417 GO_REF:0000107 RGD:9587812 NCBI chr 3:128,479,422...128,493,201
Ensembl chr 3:128,479,427...128,493,201 		JBrowse link
G IL13 interleukin 13 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15944273) Ensembl
MGI		 PMID:15944273 GO_REF:0000107 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL4 interleukin 4 acts_upstream_of_or_within ISO (PMID:15944273) MGI PMID:15944273 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL4R interleukin 4 receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15944273) Ensembl
MGI		 PMID:15944273 GO_REF:0000107 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G MS4A2 membrane spanning 4-domains A2 ISO RGD PMID:16177098 RGD:1578516 NCBI chr11:60,088,259...60,098,467
Ensembl chr11:60,088,261...60,098,467 		JBrowse link
G PLD2 phospholipase D2 ISO RGD PMID:16861349 RGD:2299903 NCBI chr17:4,807,152...4,823,430
Ensembl chr17:4,807,152...4,823,434 		JBrowse link
G SPHK2 sphingosine kinase 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:48,619,506...48,630,405
Ensembl chr19:48,619,291...48,630,717 		JBrowse link
G STXBP1 syntaxin binding protein 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:23487749 GO_REF:0000107 RGD:12904029 NCBI chr 9:127,611,912...127,696,029
Ensembl chr 9:127,579,370...127,696,027 		JBrowse link
G STXBP2 syntaxin binding protein 2 ISO RGD PMID:23487749 RGD:12904029 NCBI chr19:7,629,793...7,647,873
Ensembl chr19:7,636,772...7,647,873 		JBrowse link
G SYK spleen associated tyrosine kinase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9000133) RGD
MGI
Ensembl		 PMID:9000133 PMID:16861349 GO_REF:0000107 RGD:2299903 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549 		JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLA2G3 phospholipase A2 group III involved_in IEA
IDA		 (PMID:23624557) Ensembl
UniProt		 PMID:23624557 GO_REF:0000107 NCBI chr22:31,134,807...31,140,508
Ensembl chr22:31,134,807...31,140,508 		JBrowse link
G SNX4 sorting nexin 4 involved_in IMP (PMID:18253931) UniProt PMID:18253931 NCBI chr 3:125,446,650...125,520,202
Ensembl chr 3:125,446,650...125,520,202 		JBrowse link
G VAMP7 vesicle associated membrane protein 7 involved_in IMP (PMID:18253931) UniProt PMID:18253931 NCBI chr  X:155,881,345...155,943,769
NCBI chr  Y:57,067,865...57,130,289
Ensembl chr  Y:57,067,865...57,130,289
Ensembl chr  X:57,067,865...57,130,289 		JBrowse link
G VAMP8 vesicle associated membrane protein 8 involved_in IMP (PMID:18253931) UniProt PMID:18253931 NCBI chr 2:85,577,586...85,582,031
Ensembl chr 2:85,561,562...85,582,031 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20486
    immune system process 3294
      immune effector process 835
        positive regulation of immune effector process 302
          positive regulation of leukocyte degranulation 33
            positive regulation of mast cell degranulation 22
              positive regulation of histamine secretion by mast cell 4
              positive regulation of mast cell degranulation in another organism 0
Path 2
Term Annotations click to browse term
  biological_process 20486
    localization 5974
      establishment of localization 5308
        transport 4885
          secretion 1252
            secretion by cell 1074
              exocytosis 427
                regulated exocytosis 277
                  leukocyte degranulation 96
                    regulation of leukocyte degranulation 55
                      positive regulation of leukocyte degranulation 33
                        positive regulation of mast cell degranulation 22
                          positive regulation of histamine secretion by mast cell 4
                          positive regulation of mast cell degranulation in another organism 0
paths to the root