Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of leukocyte degranulation
go back to main search page
Accession:GO:0043302 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of leukocyte degranulation.
Synonyms:exact_synonym: positive regulation of immune cell degranulation;   positive regulation of leucocyte degranulation;   up regulation of leukocyte degranulation;   upregulation of leukocyte degranulation
 narrow_synonym: activation of leukocyte degranulation;   stimulation of leukocyte degranulation


show annotations for term's descendants           Sort by:
 
positive regulation of eosinophil degranulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 ISO (PMID:11714832) RGD PMID:11714832 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G Stx4 syntaxin 4 IEA
ISO
GO_REF:0000107
(PMID:16677249)
Ensembl
RGD
PMID:16677249 GO_REF:0000107 NCBI chr 1:199,287,384...199,295,606
Ensembl chr 1:199,287,710...199,294,979
JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nppa natriuretic peptide A IDA PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Pla2g3 phospholipase A2, group III ISO (PMID:23624557)
(MGI:5492190|PMID:23624557)
RGD PMID:23624557 MGI:5492190 NCBI chr14:83,724,828...83,730,614
Ensembl chr14:83,724,933...83,730,614
JBrowse link
G Snx4 sorting nexin 4 ISO (PMID:18253931) RGD PMID:18253931 NCBI chr11:70,693,381...70,753,620
Ensembl chr11:70,693,366...70,753,632
JBrowse link
G Vamp7 vesicle-associated membrane protein 7 ISO (PMID:18253931) RGD PMID:18253931 NCBI chr12:18,996,566...19,033,714
Ensembl chr12:18,996,591...19,030,381
JBrowse link
G Vamp8 vesicle-associated membrane protein 8 IEA
ISO
GO_REF:0000107
(PMID:18253931)
Ensembl
RGD
PMID:18253931 GO_REF:0000107 NCBI chr 4:100,250,301...100,252,756
Ensembl chr 4:100,250,301...100,252,755
JBrowse link
positive regulation of mast cell degranulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor IEA
ISO
GO_REF:0000107
(MGI:3776334|PMID:11454903)
Ensembl
RGD
PMID:11454903 GO_REF:0000107, MGI:3776334 NCBI chr10:48,569,563...48,586,366
Ensembl chr10:48,569,555...48,586,365
JBrowse link
G Adora3 adenosine A3 receptor ISO MGI:2155986 (MGI:2664591|PMID:12817016) RGD PMID:12817016 MGI:2664591 NCBI chr 2:208,336,909...208,379,217
Ensembl chr 2:208,373,154...208,376,803
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IMP RGD PMID:18209484 RGD:5130941 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645
JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia ISO (MGI:85068|PMID:9000133) RGD PMID:9000133 MGI:85068 NCBI chr13:91,727,253...91,737,106
Ensembl chr13:91,730,925...91,737,053
JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig ISO MGI:2384004 (MGI:3029067|PMID:14764707) RGD PMID:14764707 MGI:3029067 NCBI chr13:89,601,894...89,606,326
Ensembl chr13:89,601,896...89,606,326
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase ISS
ISO
GO_REF:0000024
(MGI:5294498|PMID:21746961)
UniProt
RGD
PMID:21746961 GO_REF:0000024, MGI:5294498 NCBI chr 5:151,172,189...151,199,746
Ensembl chr 5:151,172,206...151,199,745
JBrowse link
G Gab2 GRB2-associated binding protein 2 ISS
ISO
GO_REF:0000024
(MGI:2137187|PMID:11449275)
UniProt
RGD
PMID:11449275 GO_REF:0000024, MGI:2137187 NCBI chr 1:162,082,876...162,283,379
Ensembl chr 1:162,083,030...162,279,727
JBrowse link
G Gata1 GATA binding protein 1 IMP RGD PMID:22390417 RGD:9587812 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066
JBrowse link
G Gata2 GATA binding protein 2 IMP RGD PMID:22390417 RGD:9587812 NCBI chr 4:120,129,028...120,142,490
Ensembl chr 4:120,133,713...120,142,488
JBrowse link
G Il13 interleukin 13 ISO MGI:1931804|MGI:96556 (MGI:3589858|PMID:15944273) RGD PMID:15944273 MGI:3589858 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il4 interleukin 4 ISO
IBA
MGI:1857195|MGI:96541 (MGI:3589858|PMID:15944273)
PMID:21873635
RGD PMID:15944273, PMID:21873635 MGI:3589858, RGD:13792537 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il4r interleukin 4 receptor ISO MGI:1861951 (MGI:3589858|PMID:15944273) RGD PMID:15944273 MGI:3589858 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Ms4a2 membrane spanning 4-domains A2 IMP RGD PMID:16177098 RGD:1578516 NCBI chr 1:227,957,363...227,965,312
Ensembl chr 1:227,957,302...227,965,386
JBrowse link
G Nppc natriuretic peptide C IDA PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 9:93,731,436...93,735,636
Ensembl chr 9:93,731,436...93,735,636
JBrowse link
G Pld2 phospholipase D2 IMP RGD PMID:16861349 RGD:2299903 NCBI chr10:57,161,921...57,181,148
Ensembl chr10:57,163,174...57,179,730
JBrowse link
G Sphk2 sphingosine kinase 2 ISO (MGI:3703830|PMID:17346996) RGD PMID:17346996 MGI:3703830 NCBI chr 1:101,692,972...101,700,604
Ensembl chr 1:101,692,973...101,697,277
JBrowse link
G Stxbp1 syntaxin binding protein 1 IMP RGD PMID:23487749 RGD:12904029 NCBI chr 3:11,823,779...11,885,479
Ensembl chr 3:11,823,785...11,885,417
JBrowse link
G Stxbp2 syntaxin binding protein 2 IMP RGD PMID:23487749 RGD:12904029 NCBI chr12:2,180,101...2,191,863
Ensembl chr12:2,180,150...2,191,175
JBrowse link
G Syk spleen associated tyrosine kinase IMP
IBA
ISO
IEA
PMID:21873635
MGI:2384078 (MGI:85068|PMID:9000133)
GO_REF:0000107
RGD
Ensembl
PMID:9000133, PMID:16861349, PMID:21873635 GO_REF:0000107, MGI:85068, RGD:2299903, RGD:13792537 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573
JBrowse link
positive regulation of natural killer cell degranulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 ISO (PMID:23632890) RGD PMID:23632890 NCBI chr19:41,805,252...41,860,076 JBrowse link
G Cd160 CD160 molecule ISO (PMID:19109136) RGD PMID:19109136 NCBI chr 2:198,933,681...198,965,380
Ensembl chr 2:198,935,133...198,942,732
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 ISO (PMID:23632890) RGD PMID:23632890 NCBI chr16:81,689,576...81,714,341
Ensembl chr16:81,689,335...81,714,419
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 ISO (PMID:27455421) RGD PMID:27455421 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
positive regulation of neutrophil degranulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd177 CD177 molecule ISO
IBA
UniProtKB:P05107|UniProtKB:P11215 (PMID:21193407)
PMID:21873635
RGD PMID:21193407, PMID:21873635 RGD:13792537 NCBI chr 1:82,964,683...82,987,306
Ensembl chr 1:82,964,683...82,987,253
JBrowse link
G Itgam integrin subunit alpha M ISO UniProtKB:P05107|UniProtKB:Q8N6Q3 (PMID:21193407) RGD PMID:21193407 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Itgb2 integrin subunit beta 2 ISO UniProtKB:P11215|UniProtKB:Q8N6Q3 (PMID:21193407) RGD PMID:21193407 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G LOC100909620 CD177 antigen-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:81,555,412...81,560,629
Ensembl chr 1:81,555,412...81,559,685
JBrowse link
G LOC100909700 CD177 antigen-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:81,609,177...81,627,763
Ensembl chr 1:81,609,433...81,627,710
JBrowse link
G LOC100910565 CD177 antigen-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:81,548,679...81,551,288
Ensembl chr 1:81,548,892...81,550,598
JBrowse link
G LOC102553892 CD177 antigen-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:82,947,303...82,952,884
Ensembl chr 1:82,948,488...82,952,936
JBrowse link
G Ptafr platelet-activating factor receptor IMP RGD PMID:2829894 RGD:10041060 NCBI chr 5:150,746,284...150,775,675
Ensembl chr 5:150,754,021...150,775,672
JBrowse link
G RGD1564380 similar to BC049730 protein IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:82,830,153...82,902,864
Ensembl chr 1:82,831,952...82,918,444
JBrowse link
G RGD1565655 similar to BC049730 protein IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:81,592,004...81,597,637
Ensembl chr 1:81,593,800...81,596,819
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20030
    immune system process 2842
      immune effector process 875
        positive regulation of immune effector process 251
          positive regulation of leukocyte degranulation 40
            positive regulation of basophil degranulation 0
            positive regulation of cytotoxic T cell degranulation 0
            positive regulation of eosinophil degranulation 2
            positive regulation of mast cell degranulation + 24
            positive regulation of natural killer cell degranulation 4
            positive regulation of neutrophil degranulation 10
Path 2
Term Annotations click to browse term
  biological_process 20030
    localization 6478
      establishment of localization 4886
        transport 4734
          secretion 1153
            secretion by cell 956
              exocytosis 427
                regulated exocytosis 293
                  leukocyte degranulation 90
                    regulation of leukocyte degranulation 60
                      positive regulation of leukocyte degranulation 40
                        positive regulation of basophil degranulation 0
                        positive regulation of cytotoxic T cell degranulation 0
                        positive regulation of eosinophil degranulation 2
                        positive regulation of mast cell degranulation + 24
                        positive regulation of natural killer cell degranulation 4
                        positive regulation of neutrophil degranulation 10
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.