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Gene: PLA2G3 (phospholipase A2 group III) Homo sapiens
Symbol: PLA2G3
Name: phospholipase A2 group III
Description: Exhibits calcium-dependent phospholipase A2 activity. Involved in several processes, including glycerophospholipid metabolic process; plasma lipoprotein particle remodeling; and regulation of intracellular transport. Localizes to centriole and recycling endosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GIII sPLA2; GIII-SPLA2; group 3 secretory phospholipase A2; group III secreted phospholipase A2; group III secretory phospholipase A2; phosphatidylcholine 2-acylhydrolase 3; phosphatidylcholine 2-acylhydrolase GIII; phospholipase A2, group III; sPLA2-III; SPLA2III
Mus musculus (house mouse) : Pla2g3 (phospholipase A2, group III)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pla2g3 (phospholipase A2, group III)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pla2g3 (phospholipase A2 group III)
Pan paniscus (bonobo/pygmy chimpanzee) : PLA2G3 (phospholipase A2 group III)
Canis lupus familiaris (dog) : PLA2G3 (phospholipase A2 group III)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pla2g3 (phospholipase A2 group III)
Sus scrofa (pig) : PLA2G3 (phospholipase A2 group III)
Chlorocebus sabaeus (African green monkey) : PLA2G3 (phospholipase A2 group III)
Heterocephalus glaber (naked mole-rat) : Pla2g3 (phospholipase A2 group III)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2231,134,807 - 31,140,508 (-)EnsemblGRCh38hg38GRCh38
GRCh382231,134,807 - 31,140,508 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372231,530,793 - 31,536,469 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362229,860,793 - 29,866,469 (-)NCBINCBI36hg18NCBI36
Build 342229,855,346 - 29,861,023NCBI
Celera2215,330,868 - 15,336,544 (-)NCBI
Cytogenetic Map22q12.2NCBI
HuRef2214,492,451 - 14,498,127 (-)NCBIHuRef
CHM1_12231,490,658 - 31,496,458 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PLA2G3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1313284
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.