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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of mast cell degranulation
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Accession:GO:0043306 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of mast cell degranulation.
Synonyms:exact_synonym: positive regulation of mast cell granule exocytosis;   up regulation of mast cell degranulation;   upregulation of mast cell degranulation
 narrow_synonym: activation of mast cell degranulation;   stimulation of mast cell degranulation



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positive regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11454903) Ensembl
MGI
PMID:11454903 GO_REF:0000107 NCBI chr17:15,850,362...15,975,746
Ensembl chr17:15,945,130...15,975,746
JBrowse link
G ADORA3 adenosine A3 receptor acts_upstream_of_or_within ISO (PMID:12817016) MGI PMID:12817016 NCBI chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO RGD PMID:18209484 RGD:5130941 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,277...45,835,828
JBrowse link
G FCER1A Fc epsilon receptor Ia acts_upstream_of_or_within ISO (PMID:9000133) MGI PMID:9000133 NCBI chr 1:159,283,575...159,308,202
Ensembl chr 1:159,289,714...159,308,224
JBrowse link
G FCER1G Fc epsilon receptor Ig acts_upstream_of_or_within ISO (PMID:14764707) MGI PMID:14764707 NCBI chr 1:161,215,295...161,219,245
Ensembl chr 1:161,215,234...161,220,699
JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:27,612,064...27,635,185
Ensembl chr 1:27,612,064...27,635,185
JBrowse link
G GAB2 GRB2 associated binding protein 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr11:78,215,293...78,417,820
Ensembl chr11:78,215,293...78,418,348
JBrowse link
G GATA1 GATA binding protein 1 involved_in ISO
IEA
RGD
Ensembl
PMID:22390417 GO_REF:0000107 RGD:9587812 NCBI chr  X:48,786,590...48,794,311
Ensembl chr  X:48,786,540...48,794,311
JBrowse link
G GATA2 GATA binding protein 2 involved_in ISO
IEA
RGD
Ensembl
PMID:22390417 GO_REF:0000107 RGD:9587812 NCBI chr 3:128,479,422...128,493,201
Ensembl chr 3:128,479,427...128,493,201
JBrowse link
G IL13 interleukin 13 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15944273) Ensembl
MGI
PMID:15944273 GO_REF:0000107 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
JBrowse link
G IL4 interleukin 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15944273) TreeGrafter
MGI
PMID:15944273 GO_REF:0000118 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL4R interleukin 4 receptor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15944273) Ensembl
MGI
PMID:15944273 GO_REF:0000107 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778
JBrowse link
G MS4A2 membrane spanning 4-domains A2 ISO RGD PMID:16177098 RGD:1578516 NCBI chr11:60,088,259...60,098,467
Ensembl chr11:60,088,261...60,098,467
JBrowse link
G NPPC natriuretic peptide C involved_in ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 2:231,921,809...231,926,396
Ensembl chr 2:231,921,809...231,926,396
JBrowse link
G PLD2 phospholipase D2 ISO RGD PMID:16861349 RGD:2299903 NCBI chr17:4,807,152...4,823,430
Ensembl chr17:4,807,152...4,823,434
JBrowse link
G SPHK2 sphingosine kinase 2 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr19:48,619,506...48,630,405
Ensembl chr19:48,619,291...48,630,717
JBrowse link
G STXBP1 syntaxin binding protein 1 involved_in ISO
IEA
RGD
Ensembl
PMID:23487749 GO_REF:0000107 RGD:12904029 NCBI chr 9:127,611,912...127,696,029
Ensembl chr 9:127,579,370...127,696,027
JBrowse link
G STXBP2 syntaxin binding protein 2 ISO RGD PMID:23487749 RGD:12904029 NCBI chr19:7,629,793...7,647,873
Ensembl chr19:7,636,772...7,647,873
JBrowse link
G SYK spleen associated tyrosine kinase acts_upstream_of_or_within
involved_in
ISO
IEA
IBA
(PMID:9000133) RGD
MGI
TreeGrafter
GO_Central
Ensembl
PMID:9000133 PMID:16861349 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:2299903 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549
JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPPA natriuretic peptide A involved_in ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IEA
IDA
(PMID:23624557) Ensembl
UniProt
PMID:23624557 GO_REF:0000107 NCBI chr22:31,134,807...31,140,508
Ensembl chr22:31,134,807...31,140,508
JBrowse link
G SNX4 sorting nexin 4 involved_in IMP (PMID:18253931) UniProt PMID:18253931 NCBI chr 3:125,446,650...125,520,202
Ensembl chr 3:125,446,650...125,520,202
JBrowse link
G VAMP7 vesicle associated membrane protein 7 involved_in IMP (PMID:18253931) UniProt PMID:18253931 NCBI chr  X:155,881,345...155,943,769
NCBI chr  Y:57,067,865...57,130,289
Ensembl chr  Y:57,067,865...57,130,289
Ensembl chr  X:57,067,865...57,130,289
JBrowse link
G VAMP8 vesicle associated membrane protein 8 involved_in IMP (PMID:18253931) UniProt PMID:18253931 NCBI chr 2:85,577,586...85,582,031
Ensembl chr 2:85,561,562...85,582,031
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19770
    immune system process 3213
      immune effector process 821
        positive regulation of immune effector process 304
          positive regulation of leukocyte degranulation 35
            positive regulation of mast cell degranulation 24
              positive regulation of histamine secretion by mast cell 5
              positive regulation of mast cell degranulation in another organism 0
Path 2
Term Annotations click to browse term
  biological_process 19770
    localization 5924
      establishment of localization 5199
        transport 4854
          secretion 1245
            secretion by cell 1066
              exocytosis 430
                regulated exocytosis 281
                  leukocyte degranulation 99
                    regulation of leukocyte degranulation 58
                      positive regulation of leukocyte degranulation 35
                        positive regulation of mast cell degranulation 24
                          positive regulation of histamine secretion by mast cell 5
                          positive regulation of mast cell degranulation in another organism 0
paths to the root