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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of mast cell degranulation
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Accession:GO:0043306 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of mast cell degranulation.
Synonyms:exact_synonym: positive regulation of mast cell granule exocytosis;   up regulation of mast cell degranulation;   upregulation of mast cell degranulation
 narrow_synonym: activation of mast cell degranulation;   stimulation of mast cell degranulation


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positive regulation of mast cell degranulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor ISO (MGI:3776334|PMID:11454903) MGI PMID:11454903 MGI:3776334 NCBI chr17:15,927,782...15,975,746
Ensembl chr17:15,944,917...15,975,746
JBrowse link
G ADORA3 adenosine A3 receptor ISO (MGI:2664591|PMID:12817016) MGI PMID:12817016 MGI:2664591 NCBI chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO RGD PMID:18209484 RGD:5130941 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,280...45,835,828
JBrowse link
G FCER1A Fc fragment of IgE receptor Ia ISO (MGI:85068|PMID:9000133) MGI PMID:9000133 MGI:85068 NCBI chr 1:159,283,575...159,308,202
Ensembl chr 1:159,289,714...159,308,224
JBrowse link
G FCER1G Fc fragment of IgE receptor Ig ISO (MGI:3029067|PMID:14764707) MGI PMID:14764707 MGI:3029067 NCBI chr 1:161,215,295...161,219,245
Ensembl chr 1:161,215,234...161,220,699
JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase ISS UniProtKB GO_REF:0000024 NCBI chr 1:27,612,064...27,635,561
Ensembl chr 1:27,612,064...27,635,185
JBrowse link
G GAB2 GRB2 associated binding protein 2 ISS UniProtKB GO_REF:0000024 NCBI chr11:78,215,293...78,417,820
Ensembl chr11:78,215,293...78,418,348
JBrowse link
G GATA1 GATA binding protein 1 ISO RGD PMID:22390417 RGD:9587812 NCBI chr  X:48,786,590...48,794,311
Ensembl chr  X:48,786,562...48,794,311
Ensembl chr  X:48,786,562...48,794,311
JBrowse link
G GATA2 GATA binding protein 2 IEA Ensembl GO_REF:0000107 NCBI chr 3:128,479,422...128,493,201
Ensembl chr 3:128,479,427...128,493,201
Ensembl chr 3:128,479,427...128,493,201
JBrowse link
G IL13 interleukin 13 IEA Ensembl GO_REF:0000107 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
JBrowse link
G IL4 interleukin 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL4R interleukin 4 receptor IEA Ensembl GO_REF:0000107 NCBI chr16:27,313,668...27,364,778
Ensembl chr16:27,313,668...27,364,778
JBrowse link
G MS4A2 membrane spanning 4-domains A2 ISO RGD PMID:16177098 RGD:1578516 NCBI chr11:60,088,261...60,098,467
Ensembl chr11:60,088,261...60,098,467
JBrowse link
G NPPC natriuretic peptide C ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 2:231,921,809...231,926,405
Ensembl chr 2:231,921,809...231,926,396
JBrowse link
G PLD2 phospholipase D2 ISO RGD PMID:16861349 RGD:2299903 NCBI chr17:4,807,152...4,823,432
Ensembl chr17:4,807,152...4,823,434
JBrowse link
G SPHK2 sphingosine kinase 2 ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr19:48,619,409...48,630,407
Ensembl chr19:48,619,291...48,630,717
JBrowse link
G STXBP1 syntaxin binding protein 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:127,611,912...127,696,029
Ensembl chr 9:127,579,370...127,696,027
JBrowse link
G STXBP2 syntaxin binding protein 2 ISO RGD PMID:23487749 RGD:12904029 NCBI chr19:7,637,110...7,647,873
Ensembl chr19:7,636,881...7,647,873
JBrowse link
G SYK spleen associated tyrosine kinase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549
JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPPA natriuretic peptide A IEA Ensembl GO_REF:0000107 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
JBrowse link
G PLA2G3 phospholipase A2 group III IDA (PMID:23624557) UniProt PMID:23624557 NCBI chr22:31,134,807...31,140,508
Ensembl chr22:31,134,807...31,140,508
JBrowse link
G SNX4 sorting nexin 4 IMP (PMID:18253931) UniProtKB PMID:18253931 NCBI chr 3:125,446,644...125,520,202
Ensembl chr 3:125,446,650...125,520,202
JBrowse link
G VAMP7 vesicle associated membrane protein 7 IMP (PMID:18253931) UniProtKB PMID:18253931 NCBI chr  X:155,881,318...155,943,769
NCBI chr  Y:57,067,838...57,130,289
Ensembl chr  X:155,881,345...155,943,769
JBrowse link
G VAMP8 vesicle associated membrane protein 8 IMP (PMID:18253931) UniProtKB PMID:18253931 NCBI chr 2:85,577,535...85,582,031
Ensembl chr 2:85,561,562...85,582,031
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18678
    immune system process 3588
      positive regulation of immune system process 1176
        positive regulation of immune response 827
          positive regulation of mast cell activation involved in immune response 24
            positive regulation of mast cell degranulation 24
              positive regulation of histamine secretion by mast cell 5
              positive regulation of mast cell degranulation in other organism 0
Path 2
Term Annotations click to browse term
  biological_process 18678
    localization 7230
      establishment of localization 5672
        transport 5520
          secretion 1709
            secretion by cell 1537
              exocytosis 982
                regulated exocytosis 853
                  leukocyte degranulation 560
                    regulation of leukocyte degranulation 57
                      positive regulation of leukocyte degranulation 35
                        positive regulation of mast cell degranulation 24
                          positive regulation of histamine secretion by mast cell 5
                          positive regulation of mast cell degranulation in other organism 0
paths to the root