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Gene: MS4A2 (membrane spanning 4-domains A2) Homo sapiens
Symbol: MS4A2
Name: membrane spanning 4-domains A2
Description: Predicted to have IgE binding activity. Involved in immune response. Predicted to localize to the plasma membrane. Implicated in asthma; atopic dermatitis; and rhinitis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: APY; ATOPY; beta polypeptide; Fc fragment of IgE, high affinity I, receptor for; Fc fragment of IgE, high affinity I, receptor for, beta polypeptide; FCER1B; FCERI; high affinity IgE receptor beta subunit; High affinity immunoglobulin epsilon receptor beta-subunit (FcERI) (IgE Fc receptor, beta-subunit) (Fc epsilon receptor I beta-chain); high affinity immunoglobulin epsilon receptor subunit beta; igE Fc receptor subunit beta; IGEL; IGER; IGHER; immunoglobulin E receptor, high affinity, beta polypeptide; membrane-spanning 4-domains subfamily A member 2; membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for, beta polypeptide); MS4A1
Mus musculus (house mouse) : Ms4a2 (membrane-spanning 4-domains, subfamily A, member 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ms4a2 (membrane spanning 4-domains A2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ms4a2 (membrane spanning 4-domains A2)
Pan paniscus (bonobo/pygmy chimpanzee) : MS4A2 (membrane spanning 4-domains A2)
Canis lupus familiaris (dog) : MS4A2 (membrane spanning 4-domains A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ms4a2 (membrane spanning 4-domains A2)
Sus scrofa (pig) : MS4A2 (membrane spanning 4-domains A2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381160,088,261 - 60,098,467 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371159,855,734 - 59,865,940 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,612,713 - 59,622,593 (+)NCBINCBI36hg18NCBI36
Build 341159,612,712 - 59,622,593NCBI
Celera1157,220,517 - 57,230,320 (+)NCBI
Cytogenetic Map11q12.1NCBI
HuRef1156,203,291 - 56,213,094 (+)NCBIHuRef
CHM1_11159,722,124 - 59,731,922 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MS4A2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350065
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.