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Gene: MS4A2 (membrane spanning 4-domains A2) Homo sapiens
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Symbol: MS4A2
Name: membrane spanning 4-domains A2
Description: Predicted to have IgE binding activity. Involved in immune response. Predicted to localize to the plasma membrane. Implicated in asthma; atopic dermatitis; and rhinitis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: APY; ATOPY; beta polypeptide; Fc fragment of IgE, high affinity I, receptor for; Fc fragment of IgE, high affinity I, receptor for, beta polypeptide; FCER1B; FCERI; high affinity IgE receptor beta subunit; High affinity immunoglobulin epsilon receptor beta-subunit (FcERI) (IgE Fc receptor, beta-subunit) (Fc epsilon receptor I beta-chain); high affinity immunoglobulin epsilon receptor subunit beta; igE Fc receptor subunit beta; IGEL; IGER; IGHER; immunoglobulin E receptor, high affinity, beta polypeptide; membrane-spanning 4-domains subfamily A member 2; membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for, beta polypeptide); MS4A1
Orthologs:
Mus musculus (house mouse) : Ms4a2 (membrane-spanning 4-domains, subfamily A, member 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ms4a2 (membrane spanning 4-domains A2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ms4a2 (membrane spanning 4-domains A2)
Pan paniscus (bonobo/pygmy chimpanzee) : MS4A2 (membrane spanning 4-domains A2)
Canis lupus familiaris (dog) : MS4A2 (membrane spanning 4-domains A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ms4a2 (membrane spanning 4-domains A2)
Sus scrofa (pig) : MS4A2 (membrane spanning 4-domains A2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381160,088,261 - 60,098,467 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371159,855,734 - 59,865,940 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,612,713 - 59,622,593 (+)NCBINCBI36hg18NCBI36
Build 341159,612,712 - 59,622,593NCBI
Celera1157,220,517 - 57,230,320 (+)NCBI
Cytogenetic Map11q12.1NCBI
HuRef1156,203,291 - 56,213,094 (+)NCBIHuRef
CHM1_11159,722,124 - 59,731,922 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MS4A2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350065
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.