ONTOLOGY REPORT - ANNOTATIONS
Term: metalloexopeptidase activity
Accession: GO:0008235
browse the term
Definition: Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
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Dpp3
dipeptidyl peptidase 3
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936599:3,076,909...3,098,012
Ensembl chrNW_004936599:3,076,909...3,097,785
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Erap1
endoplasmic reticulum aminopeptidase 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936523:6,661,119...6,686,988
Ensembl chrNW_004936523:6,661,315...6,690,425
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Ermp1
endoplasmic reticulum metallopeptidase 1
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936539:395,671...451,611
Ensembl chrNW_004936539:408,015...451,783
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LOC101965734
U8 snoRNA-decapping enzyme
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936529:4,825,277...4,827,011
Ensembl chrNW_004936529:4,825,189...4,826,886
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Metap2
methionyl aminopeptidase 2
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936507:11,624,696...11,661,632
Ensembl chrNW_004936507:11,624,060...11,660,875
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Anpep
alanyl aminopeptidase, membrane
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936483:15,563,540...15,582,521
Ensembl chrNW_004936483:15,563,528...15,589,601
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Aopep
aminopeptidase O (putative)
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936626:3,704,474...3,973,913
Ensembl chrNW_004936626:3,667,123...3,970,433
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Dnpep
aspartyl aminopeptidase
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936569:1,770,958...1,780,224
Ensembl chrNW_004936569:1,770,936...1,780,507
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Enpep
glutamyl aminopeptidase
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936563:1,585,450...1,665,663
Ensembl chrNW_004936563:1,585,471...1,665,677
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Erap1
endoplasmic reticulum aminopeptidase 1
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936523:6,661,119...6,686,988
Ensembl chrNW_004936523:6,661,315...6,690,425
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Erap2
endoplasmic reticulum aminopeptidase 2
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936523:6,545,281...6,584,403
Ensembl chrNW_004936523:6,544,207...6,584,452
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Lap3
leucine aminopeptidase 3
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936477:10,596,610...10,627,149
Ensembl chrNW_004936477:10,596,416...10,627,239
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Lnpep
leucyl and cystinyl aminopeptidase
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936523:6,443,571...6,533,122
Ensembl chrNW_004936523:6,445,939...6,532,566
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Lta4h
leukotriene A4 hydrolase
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936507:12,082,373...12,120,078
Ensembl chrNW_004936507:12,082,068...12,120,091
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Lvrn
laeverin
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936742:1,124,286...1,207,439
Ensembl chrNW_004936742:1,124,524...1,206,008
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Metap1
methionyl aminopeptidase 1
enables
IEA
InterPro TreeGrafter UniProt
GO_REF:0000002 GO_REF:0000104 GO_REF:0000118
NCBI chrNW_004936520:3,815,693...3,873,003
Ensembl chrNW_004936520:3,815,694...3,873,009
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Metap1d
methionyl aminopeptidase type 1D, mitochondrial
enables
IEA
InterPro TreeGrafter UniProt
GO_REF:0000002 GO_REF:0000104 GO_REF:0000118
NCBI chrNW_004936509:2,204,568...2,243,470
Ensembl chrNW_004936509:2,162,717...2,243,114
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Metap2
methionyl aminopeptidase 2
enables
IEA
InterPro UniProt
GO_REF:0000002 GO_REF:0000104
NCBI chrNW_004936507:11,624,696...11,661,632
Ensembl chrNW_004936507:11,624,060...11,660,875
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Mmp14
matrix metallopeptidase 14
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936722:1,447,189...1,457,632
Ensembl chrNW_004936722:1,447,335...1,457,611
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Mmp16
matrix metallopeptidase 16
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936544:2,297,698...2,546,683
Ensembl chrNW_004936544:2,298,028...2,546,689
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Npepps
aminopeptidase puromycin sensitive
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936490:13,659,729...13,737,510
Ensembl chrNW_004936490:13,659,721...13,737,526
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Pepd
peptidase D
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936570:2,315,981...2,431,878
Ensembl chrNW_004936570:2,315,954...2,431,884
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Rnpep
arginyl aminopeptidase
enables
ISO IEA
RGD TreeGrafter
PMID:17142967
GO_REF:0000118 RGD:2325932
NCBI chrNW_004936567:2,504,544...2,524,977
Ensembl chrNW_004936567:2,504,537...2,525,018
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Rnpepl1
arginyl aminopeptidase like 1
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936745:1,049,917...1,058,817
Ensembl chrNW_004936745:1,049,924...1,058,825
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Stx16
syntaxin 16
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936530:1,231,033...1,247,961
Ensembl chrNW_004936530:1,231,252...1,247,987 Ensembl chrNW_004936530:1,231,252...1,247,987
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Trhde
thyrotropin releasing hormone degrading enzyme
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936568:1,290,758...1,660,520
Ensembl chrNW_004936568:1,290,774...1,662,542
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Xpnpep1
X-prolyl aminopeptidase 1
enables
IEA
Ensembl InterPro
GO_REF:0000002 GO_REF:0000107
NCBI chrNW_004936486:801,563...853,107
Ensembl chrNW_004936486:801,328...853,147
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Xpnpep2
X-prolyl aminopeptidase 2
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936479:1,773,797...1,883,606
Ensembl chrNW_004936479:1,773,799...1,803,104
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Xpnpep3
X-prolyl aminopeptidase 3
enables
IEA
InterPro Ensembl
GO_REF:0000002 GO_REF:0000107
NCBI chrNW_004936492:919,963...976,926
Ensembl chrNW_004936492:919,689...976,910
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Ace2
angiotensin converting enzyme 2
enables
ISO
(PMID:10924499), (PMID:10969042), (PMID:11815627)
Reactome
PMID:10924499 PMID:10969042 PMID:11815627
NCBI chrNW_004936470:4,964,526...5,011,808
Ensembl chrNW_004936470:4,965,332...5,011,702
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Aebp1
AE binding protein 1
enables
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chrNW_004936478:19,065,092...19,074,783
Ensembl chrNW_004936478:19,065,441...19,074,541
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Agbl1
AGBL carboxypeptidase 1
enables
IEA
InterPro UniProt
GO_REF:0000002 GO_REF:0000117
NCBI chrNW_004936483:12,358,731...13,056,267
Ensembl chrNW_004936483:12,358,754...12,586,674
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Agbl2
AGBL carboxypeptidase 2
enables
IEA
Ensembl UniProt InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000117
NCBI chrNW_004936562:1,563,607...1,598,451
Ensembl chrNW_004936562:1,564,607...1,593,273
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Agbl3
AGBL carboxypeptidase 3
enables
ISO
(PMID:17244817), (PMID:25103237) (MGI:5607346|PMID:25103237)
UniProt
PMID:17244817 PMID:25103237
MGI:5607346
NCBI chrNW_004936579:789,888...860,201
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Agbl5
AGBL carboxypeptidase 5
enables
IEA
InterPro UniProt Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000117
NCBI chrNW_004936493:5,470,623...5,488,542
Ensembl chrNW_004936493:5,469,449...5,488,549
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Agtpbp1
ATP/GTP binding carboxypeptidase 1
enables
IEA
Ensembl UniProt InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000117
NCBI chrNW_004936680:1,065,375...1,240,909
Ensembl chrNW_004936680:1,065,937...1,240,875
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Cpa1
carboxypeptidase A1
enables
IEA
InterPro Ensembl TreeGrafter
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936579:4,897,225...4,903,409
Ensembl chrNW_004936579:4,897,225...4,903,409
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Cpa2
carboxypeptidase A2
enables
IEA
Ensembl TreeGrafter InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936579:4,976,205...4,995,719
Ensembl chrNW_004936579:4,976,205...4,995,719
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Cpa3
carboxypeptidase A3
enables
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chrNW_004936519:6,692,466...6,718,480
Ensembl chrNW_004936519:6,692,513...6,718,425
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Cpa4
carboxypeptidase A4
enables
IEA
InterPro Ensembl TreeGrafter
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936579:4,952,235...4,972,842
Ensembl chrNW_004936579:4,952,365...4,972,837
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Cpa5
carboxypeptidase A5
enables
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chrNW_004936579:4,912,002...4,929,656
Ensembl chrNW_004936579:4,912,002...4,929,691
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Cpa6
carboxypeptidase A6
enables
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chrNW_004936496:6,484,438...6,761,816
Ensembl chrNW_004936496:6,484,438...6,761,816
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Cpb1
carboxypeptidase B1
enables
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chrNW_004936519:6,724,836...6,755,610
Ensembl chrNW_004936519:6,724,836...6,755,610
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Cpb2
carboxypeptidase B2
enables
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chrNW_004936857:577,067...609,855
Ensembl chrNW_004936857:577,585...626,267
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Cpd
carboxypeptidase D
enables
IEA
UniProt TreeGrafter InterPro
GO_REF:0000002 GO_REF:0000003 GO_REF:0000118
NCBI chrNW_004936538:6,380,046...6,454,117
Ensembl chrNW_004936538:6,379,999...6,454,122
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Cpe
carboxypeptidase E
enables
IEA
InterPro TreeGrafter Ensembl UniProt
GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936555:531,842...641,905
Ensembl chrNW_004936555:530,307...641,905
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Cpm
carboxypeptidase M
enables
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chrNW_004936545:6,739,658...6,803,501
Ensembl chrNW_004936545:6,737,851...6,803,662
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Cpn1
carboxypeptidase N subunit 1
enables
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chrNW_004936636:145,148...172,865
Ensembl chrNW_004936636:145,024...172,876
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Cpo
carboxypeptidase O
enables
IEA
InterPro TreeGrafter Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936631:3,219,512...3,243,462
Ensembl chrNW_004936631:3,219,512...3,243,462
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Cpxm1
carboxypeptidase X, M14 family member 1
enables
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chrNW_004936485:15,929,888...15,936,647
Ensembl chrNW_004936485:15,929,799...15,936,648
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Cpxm2
carboxypeptidase X, M14 family member 2
enables
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chrNW_004936486:12,250,128...12,335,578
Ensembl chrNW_004936486:12,251,199...12,345,542
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Cpz
carboxypeptidase Z
enables
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chrNW_004936477:19,792,738...19,825,066
Ensembl chrNW_004936477:19,801,698...19,825,256
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LOC101957772
BEN domain-containing protein 5
enables
IEA
InterPro UniProt Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000117
NCBI chrNW_004936474:29,600,130...29,647,142
Ensembl chrNW_004936474:29,599,327...29,647,228
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LOC101964348
glutamate carboxypeptidase 2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936736:32,617...79,968
Ensembl chrNW_004936736:32,706...79,902
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Matcap1
microtubule associated tyrosine carboxypeptidase 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936475:17,648,565...17,656,445
Ensembl chrNW_004936475:17,649,551...17,657,292
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Vash1
vasohibin 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936488:5,675,788...5,696,198
Ensembl chrNW_004936488:5,675,782...5,696,222
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Vash2
vasohibin 2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936557:622,947...661,495
Ensembl chrNW_004936557:623,934...661,857
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Adam10
ADAM metallopeptidase domain 10
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936471:19,760,709...19,911,759
Ensembl chrNW_004936471:19,758,118...19,911,759
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Adam17
ADAM metallopeptidase domain 17
enables
ISO
(PMID:14993236)
MGI
PMID:14993236
NCBI chrNW_004936532:5,864,851...5,904,005
Ensembl chrNW_004936532:5,864,867...5,904,003
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Cndp2
carnosine dipeptidase 2
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936616:3,997,670...4,016,077
Ensembl chrNW_004936616:3,998,289...4,012,904
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Cpq
carboxypeptidase Q
enables
IEA
InterPro TreeGrafter Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936470:45,489,562...45,848,412
Ensembl chrNW_004936470:45,485,926...45,848,416
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Dpep1
dipeptidase 1
enables
IEA
Ensembl InterPro
GO_REF:0000002 GO_REF:0000107
NCBI chrNW_004936641:379,112...384,711
Ensembl chrNW_004936641:379,083...391,918
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LOC101963195
dipeptidase 3
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936475:18,325,821...18,329,878
Ensembl chrNW_004936475:18,325,821...18,329,878
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LOC101963479
dipeptidase 2
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936475:18,333,523...18,339,248
Ensembl chrNW_004936475:18,333,579...18,348,640
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LOC101968921
angiotensin-converting enzyme
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936541:4,157,847...4,178,156
Ensembl chrNW_004936541:4,157,393...4,178,177
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Mep1a
meprin A subunit alpha
enables
ISO
(PMID:22923609)
MGI
PMID:22923609
NCBI chrNW_004936476:13,514,965...13,553,209
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Matcap1
microtubule associated tyrosine carboxypeptidase 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936475:17,648,565...17,656,445
Ensembl chrNW_004936475:17,649,551...17,657,292
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all