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ONTOLOGY REPORT - ANNOTATIONS


Term:metalloexopeptidase activity
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Accession:GO:0008235 term browser browse the term
Definition:Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.


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metalloexopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpp3 dipeptidyl peptidase 3 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936599:3,076,909...3,098,012
Ensembl chrNW_004936599:3,076,909...3,097,785
JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936523:6,661,119...6,686,988
Ensembl chrNW_004936523:6,661,315...6,690,425
JBrowse link
G Ermp1 endoplasmic reticulum metallopeptidase 1 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936539:395,671...451,611
Ensembl chrNW_004936539:408,015...451,783
JBrowse link
G LOC101965734 U8 snoRNA-decapping enzyme enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936529:4,825,277...4,827,011
Ensembl chrNW_004936529:4,825,189...4,826,886
JBrowse link
G Metap2 methionyl aminopeptidase 2 enables IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936507:11,624,696...11,661,632
Ensembl chrNW_004936507:11,624,060...11,660,875
JBrowse link
metalloaminopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anpep alanyl aminopeptidase, membrane enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936483:15,563,540...15,582,521
Ensembl chrNW_004936483:15,563,528...15,589,601
JBrowse link
G Aopep aminopeptidase O (putative) enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936626:3,704,474...3,973,913
Ensembl chrNW_004936626:3,667,123...3,970,433
JBrowse link
G Dnpep aspartyl aminopeptidase enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936569:1,770,958...1,780,224
Ensembl chrNW_004936569:1,770,936...1,780,507
JBrowse link
G Enpep glutamyl aminopeptidase enables IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936563:1,585,450...1,665,663
Ensembl chrNW_004936563:1,585,471...1,665,677
JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936523:6,661,119...6,686,988
Ensembl chrNW_004936523:6,661,315...6,690,425
JBrowse link
G Erap2 endoplasmic reticulum aminopeptidase 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936523:6,545,281...6,584,403
Ensembl chrNW_004936523:6,544,207...6,584,452
JBrowse link
G Lap3 leucine aminopeptidase 3 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936477:10,596,610...10,627,149
Ensembl chrNW_004936477:10,596,416...10,627,239
JBrowse link
G Lnpep leucyl and cystinyl aminopeptidase enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936523:6,443,571...6,533,122
Ensembl chrNW_004936523:6,445,939...6,532,566
JBrowse link
G Lta4h leukotriene A4 hydrolase enables IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936507:12,082,373...12,120,078
Ensembl chrNW_004936507:12,082,068...12,120,091
JBrowse link
G Lvrn laeverin enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936742:1,124,286...1,207,439
Ensembl chrNW_004936742:1,124,524...1,206,008
JBrowse link
G Metap1 methionyl aminopeptidase 1 enables IEA InterPro
TreeGrafter
UniProt
GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chrNW_004936520:3,815,693...3,873,003
Ensembl chrNW_004936520:3,815,694...3,873,009
JBrowse link
G Metap1d methionyl aminopeptidase type 1D, mitochondrial enables IEA InterPro
TreeGrafter
UniProt
GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chrNW_004936509:2,204,568...2,243,470
Ensembl chrNW_004936509:2,162,717...2,243,114
JBrowse link
G Metap2 methionyl aminopeptidase 2 enables IEA InterPro
UniProt
GO_REF:0000002 GO_REF:0000104 NCBI chrNW_004936507:11,624,696...11,661,632
Ensembl chrNW_004936507:11,624,060...11,660,875
JBrowse link
G Mmp14 matrix metallopeptidase 14 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936722:1,447,189...1,457,632
Ensembl chrNW_004936722:1,447,335...1,457,611
JBrowse link
G Mmp16 matrix metallopeptidase 16 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936544:2,297,698...2,546,683
Ensembl chrNW_004936544:2,298,028...2,546,689
JBrowse link
G Npepps aminopeptidase puromycin sensitive enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936490:13,659,729...13,737,510
Ensembl chrNW_004936490:13,659,721...13,737,526
JBrowse link
G Pepd peptidase D enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936570:2,315,981...2,431,878
Ensembl chrNW_004936570:2,315,954...2,431,884
JBrowse link
G Rnpep arginyl aminopeptidase enables ISO
IEA
RGD
TreeGrafter
PMID:17142967 GO_REF:0000118 RGD:2325932 NCBI chrNW_004936567:2,504,544...2,524,977
Ensembl chrNW_004936567:2,504,537...2,525,018
JBrowse link
G Rnpepl1 arginyl aminopeptidase like 1 enables IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936745:1,049,917...1,058,817
Ensembl chrNW_004936745:1,049,924...1,058,825
JBrowse link
G Stx16 syntaxin 16 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936530:1,231,033...1,247,961
Ensembl chrNW_004936530:1,231,252...1,247,987
Ensembl chrNW_004936530:1,231,252...1,247,987
JBrowse link
G Trhde thyrotropin releasing hormone degrading enzyme enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936568:1,290,758...1,660,520
Ensembl chrNW_004936568:1,290,774...1,662,542
JBrowse link
G Xpnpep1 X-prolyl aminopeptidase 1 enables IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936486:801,563...853,107
Ensembl chrNW_004936486:801,328...853,147
JBrowse link
G Xpnpep2 X-prolyl aminopeptidase 2 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936479:1,773,797...1,883,606
Ensembl chrNW_004936479:1,773,799...1,803,104
JBrowse link
G Xpnpep3 X-prolyl aminopeptidase 3 enables IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936492:919,963...976,926
Ensembl chrNW_004936492:919,689...976,910
JBrowse link
metallocarboxypeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin converting enzyme 2 enables ISO (PMID:10924499), (PMID:10969042), (PMID:11815627) Reactome PMID:10924499 PMID:10969042 PMID:11815627 NCBI chrNW_004936470:4,964,526...5,011,808
Ensembl chrNW_004936470:4,965,332...5,011,702
JBrowse link
G Aebp1 AE binding protein 1 enables IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004936478:19,065,092...19,074,783
Ensembl chrNW_004936478:19,065,441...19,074,541
JBrowse link
G Agbl1 AGBL carboxypeptidase 1 enables IEA InterPro
UniProt
GO_REF:0000002 GO_REF:0000117 NCBI chrNW_004936483:12,358,731...13,056,267
Ensembl chrNW_004936483:12,358,754...12,586,674
JBrowse link
G Agbl2 AGBL carboxypeptidase 2 enables IEA Ensembl
UniProt
InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 NCBI chrNW_004936562:1,563,607...1,598,451
Ensembl chrNW_004936562:1,564,607...1,593,273
JBrowse link
G Agbl3 AGBL carboxypeptidase 3 enables ISO (PMID:17244817), (PMID:25103237)
(MGI:5607346|PMID:25103237)
UniProt PMID:17244817 PMID:25103237 MGI:5607346 NCBI chrNW_004936579:789,888...860,201 JBrowse link
G Agbl5 AGBL carboxypeptidase 5 enables IEA InterPro
UniProt
Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 NCBI chrNW_004936493:5,470,623...5,488,542
Ensembl chrNW_004936493:5,469,449...5,488,549
JBrowse link
G Agtpbp1 ATP/GTP binding carboxypeptidase 1 enables IEA Ensembl
UniProt
InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 NCBI chrNW_004936680:1,065,375...1,240,909
Ensembl chrNW_004936680:1,065,937...1,240,875
JBrowse link
G Cpa1 carboxypeptidase A1 enables IEA InterPro
Ensembl
TreeGrafter
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936579:4,897,225...4,903,409
Ensembl chrNW_004936579:4,897,225...4,903,409
JBrowse link
G Cpa2 carboxypeptidase A2 enables IEA Ensembl
TreeGrafter
InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936579:4,976,205...4,995,719
Ensembl chrNW_004936579:4,976,205...4,995,719
JBrowse link
G Cpa3 carboxypeptidase A3 enables IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004936519:6,692,466...6,718,480
Ensembl chrNW_004936519:6,692,513...6,718,425
JBrowse link
G Cpa4 carboxypeptidase A4 enables IEA InterPro
Ensembl
TreeGrafter
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936579:4,952,235...4,972,842
Ensembl chrNW_004936579:4,952,365...4,972,837
JBrowse link
G Cpa5 carboxypeptidase A5 enables IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004936579:4,912,002...4,929,656
Ensembl chrNW_004936579:4,912,002...4,929,691
JBrowse link
G Cpa6 carboxypeptidase A6 enables IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004936496:6,484,438...6,761,816
Ensembl chrNW_004936496:6,484,438...6,761,816
JBrowse link
G Cpb1 carboxypeptidase B1 enables IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004936519:6,724,836...6,755,610
Ensembl chrNW_004936519:6,724,836...6,755,610
JBrowse link
G Cpb2 carboxypeptidase B2 enables IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004936857:577,067...609,855
Ensembl chrNW_004936857:577,585...626,267
JBrowse link
G Cpd carboxypeptidase D enables IEA UniProt
TreeGrafter
InterPro
GO_REF:0000002 GO_REF:0000003 GO_REF:0000118 NCBI chrNW_004936538:6,380,046...6,454,117
Ensembl chrNW_004936538:6,379,999...6,454,122
JBrowse link
G Cpe carboxypeptidase E enables IEA InterPro
TreeGrafter
Ensembl
UniProt
GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936555:531,842...641,905
Ensembl chrNW_004936555:530,307...641,905
JBrowse link
G Cpm carboxypeptidase M enables IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004936545:6,739,658...6,803,501
Ensembl chrNW_004936545:6,737,851...6,803,662
JBrowse link
G Cpn1 carboxypeptidase N subunit 1 enables IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004936636:145,148...172,865
Ensembl chrNW_004936636:145,024...172,876
JBrowse link
G Cpo carboxypeptidase O enables IEA InterPro
TreeGrafter
Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936631:3,219,512...3,243,462
Ensembl chrNW_004936631:3,219,512...3,243,462
JBrowse link
G Cpxm1 carboxypeptidase X, M14 family member 1 enables IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004936485:15,929,888...15,936,647
Ensembl chrNW_004936485:15,929,799...15,936,648
JBrowse link
G Cpxm2 carboxypeptidase X, M14 family member 2 enables IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004936486:12,250,128...12,335,578
Ensembl chrNW_004936486:12,251,199...12,345,542
JBrowse link
G Cpz carboxypeptidase Z enables IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004936477:19,792,738...19,825,066
Ensembl chrNW_004936477:19,801,698...19,825,256
JBrowse link
G LOC101957772 BEN domain-containing protein 5 enables IEA InterPro
UniProt
Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 NCBI chrNW_004936474:29,600,130...29,647,142
Ensembl chrNW_004936474:29,599,327...29,647,228
JBrowse link
G LOC101964348 glutamate carboxypeptidase 2 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936736:32,617...79,968
Ensembl chrNW_004936736:32,706...79,902
JBrowse link
G Matcap1 microtubule associated tyrosine carboxypeptidase 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:17,648,565...17,656,445
Ensembl chrNW_004936475:17,649,551...17,657,292
JBrowse link
G Vash1 vasohibin 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936488:5,675,788...5,696,198
Ensembl chrNW_004936488:5,675,782...5,696,222
JBrowse link
G Vash2 vasohibin 2 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936557:622,947...661,495
Ensembl chrNW_004936557:623,934...661,857
JBrowse link
metallodipeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam10 ADAM metallopeptidase domain 10 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:19,760,709...19,911,759
Ensembl chrNW_004936471:19,758,118...19,911,759
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 enables ISO (PMID:14993236) MGI PMID:14993236 NCBI chrNW_004936532:5,864,851...5,904,005
Ensembl chrNW_004936532:5,864,867...5,904,003
JBrowse link
G Cndp2 carnosine dipeptidase 2 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936616:3,997,670...4,016,077
Ensembl chrNW_004936616:3,998,289...4,012,904
JBrowse link
G Cpq carboxypeptidase Q enables IEA InterPro
TreeGrafter
Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936470:45,489,562...45,848,412
Ensembl chrNW_004936470:45,485,926...45,848,416
JBrowse link
G Dpep1 dipeptidase 1 enables IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936641:379,112...384,711
Ensembl chrNW_004936641:379,083...391,918
JBrowse link
G LOC101963195 dipeptidase 3 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936475:18,325,821...18,329,878
Ensembl chrNW_004936475:18,325,821...18,329,878
JBrowse link
G LOC101963479 dipeptidase 2 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936475:18,333,523...18,339,248
Ensembl chrNW_004936475:18,333,579...18,348,640
JBrowse link
G LOC101968921 angiotensin-converting enzyme enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936541:4,157,847...4,178,156
Ensembl chrNW_004936541:4,157,393...4,178,177
JBrowse link
G Mep1a meprin A subunit alpha enables ISO (PMID:22923609) MGI PMID:22923609 NCBI chrNW_004936476:13,514,965...13,553,209 JBrowse link
tubulin-tyrosine carboxypeptidase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Matcap1 microtubule associated tyrosine carboxypeptidase 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:17,648,565...17,656,445
Ensembl chrNW_004936475:17,649,551...17,657,292
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17094
    catalytic activity 5319
      hydrolase activity 2262
        peptidase activity 577
          metallopeptidase activity 180
            metalloexopeptidase activity 64
              metalloaminopeptidase activity 24
              metallocarboxypeptidase activity + 28
              metallodipeptidase activity 9
paths to the root