ONTOLOGY REPORT - ANNOTATIONS
Term: metalloaminopeptidase activity
Accession: GO:0070006
browse the term
Definition: Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
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Anpep
alanyl aminopeptidase, membrane
enables
IBA IEA
GO_REF:0000033 GO_REF:0000118
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789
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Aopep
aminopeptidase O
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr17:1,811,281...2,127,316
Ensembl chr17:1,811,980...2,127,331
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Dnpep
aspartyl aminopeptidase
enables
IEA
GO_REF:0000118
TreeGrafter
GO_REF:0000118
NCBI chr 9:76,799,931...76,808,841
Ensembl chr 9:76,783,966...76,808,716
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Enpep
glutamyl aminopeptidase
enables
IEA ISO ISS IBA
GO_REF:0000107 (PMID:23888046), (PMID:8346219) GO_REF:0000024 GO_REF:0000118 GO_REF:0000033
Ensembl RGD UniProt TreeGrafter GO_Central
PMID:8346219 PMID:23888046
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947
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ENSRNOG00000069260
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
Ensembl chr18:11,581,569...11,583,265
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Erap1
endoplasmic reticulum aminopeptidase 1
enables
IEA IBA
GO_REF:0000118 GO_REF:0000033
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr 2:3,931,817...3,970,735
Ensembl chr 2:3,931,904...3,972,447
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Lap3
leucine aminopeptidase 3
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr14:65,608,375...65,627,359
Ensembl chr14:65,608,376...65,627,359
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Lnpep
leucyl and cystinyl aminopeptidase
enables
IEA IBA
GO_REF:0000118 GO_REF:0000033
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr 1:58,258,642...58,355,532
Ensembl chr 1:58,258,642...58,354,544
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Lta4h
leukotriene A4 hydrolase
enables
ISO
(PMID:11675384)
RGD
PMID:11675384
NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600
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Lvrn
laeverin
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr18:39,606,047...39,675,247
Ensembl chr18:39,607,722...39,675,165
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Metap1
methionyl aminopeptidase 1
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 2:226,991,305...227,024,360
Ensembl chr 2:226,991,301...227,024,434
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Metap1d
methionyl aminopeptidase type 1D (mitochondrial)
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 3:56,279,471...56,354,518
Ensembl chr 3:56,279,493...56,351,981
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Metap2
methionyl aminopeptidase 2
enables
IEA
GO_REF:0000104
UniProt
GO_REF:0000104
NCBI chr 7:28,412,429...28,440,458
Ensembl chr 7:28,411,608...28,440,434
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Mmp14
matrix metallopeptidase 14
enables
ISO
(PMID:24970228)
RGD
PMID:24970228
NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
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Mmp16
matrix metallopeptidase 16
enables
ISO IEA
(PMID:24970228) GO_REF:0000107
RGD Ensembl
PMID:24970228
GO_REF:0000107
NCBI chr 5:31,312,280...31,556,276
Ensembl chr 5:31,312,280...31,548,388
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Npepl1
aminopeptidase-like 1
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr 3:162,893,932...162,906,491
Ensembl chr 3:162,893,943...162,906,492
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Npepps
aminopeptidase puromycin sensitive
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr10:82,191,454...82,273,967
Ensembl chr10:82,191,456...82,273,967
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Pepd
peptidase D
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr 1:87,536,650...87,681,233
Ensembl chr 1:87,536,609...87,681,231
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Rnpep
arginyl aminopeptidase
enables
IDA IEA IBA
GO_REF:0000118 GO_REF:0000033
TreeGrafter GO_Central RGD
PMID:17142967
GO_REF:0000033 GO_REF:0000118, RGD:2325932
NCBI chr13:46,699,458...46,717,829
Ensembl chr13:46,699,463...46,717,998
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Rnpepl1
arginyl aminopeptidase like 1
enables
ISO IBA
(PMID:11017071) GO_REF:0000033
RGD GO_Central
PMID:11017071
GO_REF:0000033
NCBI chr 9:93,476,600...93,486,331
Ensembl chr 9:93,472,390...93,486,331
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Trhde
thyrotropin-releasing hormone degrading enzyme
enables
IBA IEA
GO_REF:0000033 GO_REF:0000118
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr 7:49,943,271...50,350,613
Ensembl chr 7:49,945,766...50,367,371
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Xpnpep1
X-prolyl aminopeptidase 1
enables
ISS IEA ISO
GO_REF:0000024 GO_REF:0000002 (PMID:18515364), (PMID:35165443)
UniProt InterPro RGD
PMID:18515364 PMID:35165443
GO_REF:0000002 GO_REF:0000024
NCBI chr 1:252,001,366...252,052,077
Ensembl chr 1:252,001,367...252,051,479
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Xpnpep2
X-prolyl aminopeptidase 2
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr X:127,287,765...127,317,036
Ensembl chr X:127,287,979...127,317,223
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Xpnpep3
X-prolyl aminopeptidase 3
enables
IEA ISO
GO_REF:0000107 (PMID:25609706), (PMID:28476889) GO_REF:0000002
Ensembl RGD InterPro
PMID:25609706 PMID:28476889
GO_REF:0000002 GO_REF:0000107
NCBI chr 7:112,926,154...112,978,793
Ensembl chr 7:112,926,248...112,974,878
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