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ONTOLOGY REPORT - ANNOTATIONS


Term:metalloaminopeptidase activity
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Accession:GO:0070006 term browser browse the term
Definition:Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.



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metalloaminopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anpep alanyl aminopeptidase, membrane enables IBA
IEA
GO_REF:0000033
GO_REF:0000118
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789
JBrowse link
G Aopep aminopeptidase O enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:1,811,281...2,127,316
Ensembl chr17:1,811,980...2,127,331
JBrowse link
G Dnpep aspartyl aminopeptidase enables IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 9:76,799,931...76,808,841
Ensembl chr 9:76,783,966...76,808,716
JBrowse link
G Enpep glutamyl aminopeptidase enables IEA
ISO
ISS
IBA
GO_REF:0000107
(PMID:23888046), (PMID:8346219)
GO_REF:0000024
GO_REF:0000118
GO_REF:0000033
Ensembl
RGD
UniProt
TreeGrafter
GO_Central
PMID:8346219 PMID:23888046 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947
JBrowse link
G ENSRNOG00000069260 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr18:11,581,569...11,583,265 JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 enables IEA
IBA
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr 2:3,931,817...3,970,735
Ensembl chr 2:3,931,904...3,972,447
JBrowse link
G Lap3 leucine aminopeptidase 3 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:65,608,375...65,627,359
Ensembl chr14:65,608,376...65,627,359
JBrowse link
G Lnpep leucyl and cystinyl aminopeptidase enables IEA
IBA
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr 1:58,258,642...58,355,532
Ensembl chr 1:58,258,642...58,354,544
JBrowse link
G Lta4h leukotriene A4 hydrolase enables ISO (PMID:11675384) RGD PMID:11675384 NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600
JBrowse link
G Lvrn laeverin enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:39,606,047...39,675,247
Ensembl chr18:39,607,722...39,675,165
JBrowse link
G Metap1 methionyl aminopeptidase 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:226,991,305...227,024,360
Ensembl chr 2:226,991,301...227,024,434
JBrowse link
G Metap1d methionyl aminopeptidase type 1D (mitochondrial) enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:56,279,471...56,354,518
Ensembl chr 3:56,279,493...56,351,981
JBrowse link
G Metap2 methionyl aminopeptidase 2 enables IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 7:28,412,429...28,440,458
Ensembl chr 7:28,411,608...28,440,434
JBrowse link
G Mmp14 matrix metallopeptidase 14 enables ISO (PMID:24970228) RGD PMID:24970228 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Mmp16 matrix metallopeptidase 16 enables ISO
IEA
(PMID:24970228)
GO_REF:0000107
RGD
Ensembl
PMID:24970228 GO_REF:0000107 NCBI chr 5:31,312,280...31,556,276
Ensembl chr 5:31,312,280...31,548,388
JBrowse link
G Npepl1 aminopeptidase-like 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:162,893,932...162,906,491
Ensembl chr 3:162,893,943...162,906,492
JBrowse link
G Npepps aminopeptidase puromycin sensitive enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:82,191,454...82,273,967
Ensembl chr10:82,191,456...82,273,967
JBrowse link
G Pepd peptidase D enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:87,536,650...87,681,233
Ensembl chr 1:87,536,609...87,681,231
JBrowse link
G Rnpep arginyl aminopeptidase enables IDA
IEA
IBA
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
RGD
PMID:17142967 GO_REF:0000033 GO_REF:0000118, RGD:2325932 NCBI chr13:46,699,458...46,717,829
Ensembl chr13:46,699,463...46,717,998
JBrowse link
G Rnpepl1 arginyl aminopeptidase like 1 enables ISO
IBA
(PMID:11017071)
GO_REF:0000033
RGD
GO_Central
PMID:11017071 GO_REF:0000033 NCBI chr 9:93,476,600...93,486,331
Ensembl chr 9:93,472,390...93,486,331
JBrowse link
G Trhde thyrotropin-releasing hormone degrading enzyme enables IBA
IEA
GO_REF:0000033
GO_REF:0000118
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr 7:49,943,271...50,350,613
Ensembl chr 7:49,945,766...50,367,371
JBrowse link
G Xpnpep1 X-prolyl aminopeptidase 1 enables ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000002
(PMID:18515364), (PMID:35165443)
UniProt
InterPro
RGD
PMID:18515364 PMID:35165443 GO_REF:0000002 GO_REF:0000024 NCBI chr 1:252,001,366...252,052,077
Ensembl chr 1:252,001,367...252,051,479
JBrowse link
G Xpnpep2 X-prolyl aminopeptidase 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:127,287,765...127,317,036
Ensembl chr  X:127,287,979...127,317,223
JBrowse link
G Xpnpep3 X-prolyl aminopeptidase 3 enables IEA
ISO
GO_REF:0000107
(PMID:25609706), (PMID:28476889)
GO_REF:0000002
Ensembl
RGD
InterPro
PMID:25609706 PMID:28476889 GO_REF:0000002 GO_REF:0000107 NCBI chr 7:112,926,154...112,978,793
Ensembl chr 7:112,926,248...112,974,878
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  molecular_function 20893
    catalytic activity 6119
      hydrolase activity 2631
        peptidase activity 702
          exopeptidase activity 104
            aminopeptidase activity 38
              metalloaminopeptidase activity 24
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