Cpa1 (carboxypeptidase A1) - Rat Genome Database

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Gene: Cpa1 (carboxypeptidase A1) Ictidomys tridecemlineatus
Analyze
Symbol: Cpa1
Name: carboxypeptidase A1
RGD ID: 12590405
Description: ENCODES a protein that exhibits exopeptidase activity (ortholog); INVOLVED IN proteolysis involved in protein catabolic process (ortholog); response to cadmium ion (ortholog); ASSOCIATED WITH Cadmium Poisoning (ortholog); Chronic Pancreatitis (ortholog); cystic fibrosis (ortholog); FOUND IN extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511824,764,639 - 24,771,398 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365794,897,225 - 4,903,409 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365794,897,225 - 4,903,409 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cpa1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511824,764,639 - 24,771,398 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365794,897,225 - 4,903,409 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365794,897,225 - 4,903,409 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CPA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387130,380,494 - 130,388,108 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7130,380,339 - 130,388,114 (+)EnsemblGRCh38hg38GRCh38
GRCh377130,020,335 - 130,027,949 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367129,807,591 - 129,815,185 (+)NCBINCBI36Build 36hg18NCBI36
Build 347129,614,305 - 129,621,899NCBI
Celera7124,816,055 - 124,823,715 (+)NCBICelera
Cytogenetic Map7q32.2NCBI
HuRef7124,382,393 - 124,390,053 (+)NCBIHuRef
CHM1_17129,953,707 - 129,961,367 (+)NCBICHM1_1
T2T-CHM13v2.07131,694,217 - 131,701,830 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27129,405,674 - 129,413,334 (+)NCBI
Cpa1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39630,639,217 - 30,645,360 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl630,639,217 - 30,645,362 (+)EnsemblGRCm39 Ensembl
GRCm38630,639,218 - 30,645,361 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl630,639,218 - 30,645,363 (+)EnsemblGRCm38mm10GRCm38
MGSCv37630,589,221 - 30,595,361 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36630,589,231 - 30,595,371 (+)NCBIMGSCv36mm8
Celera630,649,082 - 30,655,216 (+)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map612.52NCBI
Cpa1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8460,224,801 - 60,230,928 (+)NCBIGRCr8
mRatBN7.2459,257,417 - 59,263,544 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl459,257,417 - 59,263,544 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx464,235,436 - 64,241,565 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0460,151,623 - 60,157,752 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0458,553,549 - 58,559,678 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0457,952,982 - 57,959,109 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl457,952,982 - 57,959,109 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0457,713,899 - 57,720,026 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4457,549,260 - 57,555,361 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1457,825,389 - 57,831,491 (+)NCBI
Celera454,356,336 - 54,362,463 (+)NCBICelera
Cytogenetic Map4q22NCBI
Cpa1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547911,011,928 - 11,017,908 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547911,011,928 - 11,017,908 (+)NCBIChiLan1.0ChiLan1.0
CPA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26167,198,027 - 167,208,098 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1719,208,271 - 19,218,342 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07122,335,250 - 122,353,369 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17134,862,141 - 134,871,834 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7134,861,920 - 134,871,834 (+)Ensemblpanpan1.1panPan2
CPA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1146,562,729 - 6,569,298 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl146,562,768 - 6,665,659 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha146,252,648 - 6,259,263 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0146,326,968 - 6,333,583 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl146,327,013 - 6,333,529 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1146,531,950 - 6,538,560 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0146,277,162 - 6,283,772 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0146,420,781 - 6,427,394 (-)NCBIUU_Cfam_GSD_1.0
CPA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1818,469,921 - 18,476,327 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11818,466,564 - 18,482,099 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21819,472,686 - 19,484,824 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CPA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12199,011,941 - 99,021,359 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2199,013,542 - 99,021,350 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660424,380,113 - 4,387,861 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cpa1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247835,912,447 - 5,918,430 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247835,912,419 - 5,918,446 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005331101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000009252   ⟹   ENSSTOP00000008301
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365794,897,225 - 4,903,409 (-)Ensembl
RefSeq Acc Id: XM_005331101   ⟹   XP_005331158
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440511824,764,639 - 24,771,398 (-)NCBI
SpeTri2.0NW_0049365794,897,225 - 4,903,409 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005331158 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000008301.2
GenBank Protein KAG3277481 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005331158   ⟸   XM_005331101
- UniProtKB: I3MD78 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000008301   ⟸   ENSSTOT00000009252
Protein Domains
Peptidase M14 carboxypeptidase A


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000009248 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000009252.3 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.340 UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro CPA_M14_CPD UniProtKB/TrEMBL
  M14A-like_propep UniProtKB/TrEMBL
  M14A_act_pep UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
NCBI Gene Cpa1 ENTREZGENE
PANTHER CARBOXYPEPTIDASE A1 UniProtKB/TrEMBL
  PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B UniProtKB/TrEMBL
Pfam Peptidase_M14 UniProtKB/TrEMBL
  Propep_M14 UniProtKB/TrEMBL
PRINTS CRBOXYPTASEA UniProtKB/TrEMBL
PROSITE CARBOXYPEPT_ZN_1 UniProtKB/TrEMBL
  CARBOXYPEPT_ZN_2 UniProtKB/TrEMBL
SMART Zn_pept UniProtKB/TrEMBL
Superfamily-SCOP Protease propeptides/inhibitors UniProtKB/TrEMBL
  Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt I3MD78 ENTREZGENE, UniProtKB/TrEMBL