Agbl2 (AGBL carboxypeptidase 2) - Rat Genome Database

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Gene: Agbl2 (AGBL carboxypeptidase 2) Ictidomys tridecemlineatus
Analyze
Symbol: Agbl2
Name: AGBL carboxypeptidase 2 (Ensembl:ATP/GTP binding protein like 2)
RGD ID: 12545729
Description: ENCODES a protein that exhibits metallocarboxypeptidase activity (inferred); zinc ion binding (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH congenital disorder of glycosylation type IIc (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN cell projection (inferred); centriole (inferred); ciliary basal body (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP/GTP binding protein like 2; cytosolic carboxypeptidase 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494719,452,568 - 19,509,105 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365621,564,607 - 1,593,273 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365621,563,607 - 1,598,451 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
proteolysis  (IEA)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Agbl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494719,452,568 - 19,509,105 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365621,564,607 - 1,593,273 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365621,563,607 - 1,598,451 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGBL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381147,659,591 - 47,715,369 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1147,659,591 - 47,715,389 (-)EnsemblGRCh38hg38GRCh38
GRCh371147,681,143 - 47,736,921 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361147,637,719 - 47,692,878 (-)NCBINCBI36Build 36hg18NCBI36
Celera1147,828,422 - 47,883,671 (-)NCBICelera
Cytogenetic Map11p11.2NCBI
HuRef1147,386,826 - 47,442,523 (-)NCBIHuRef
CHM1_11147,680,423 - 47,736,178 (-)NCBICHM1_1
T2T-CHM13v2.01147,824,574 - 47,880,377 (-)NCBIT2T-CHM13v2.0
Agbl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39290,613,029 - 90,664,781 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl290,613,071 - 90,664,781 (+)EnsemblGRCm39 Ensembl
GRCm38290,782,685 - 90,834,437 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl290,782,727 - 90,834,437 (+)EnsemblGRCm38mm10GRCm38
MGSCv37290,622,901 - 90,656,388 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36290,583,566 - 90,635,276 (+)NCBIMGSCv36mm8
Celera292,167,447 - 92,201,166 (+)NCBICelera
Cytogenetic Map2E1NCBI
cM Map250.37NCBI
Agbl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8397,220,654 - 97,255,905 (+)NCBIGRCr8
mRatBN7.2376,764,893 - 76,800,071 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl376,764,238 - 76,800,214 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0379,622,791 - 79,647,402 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl379,613,171 - 79,646,698 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0386,319,497 - 86,354,972 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4375,144,314 - 75,178,964 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1375,041,014 - 75,074,718 (+)NCBI
Celera375,973,609 - 76,009,281 (+)NCBICelera
Cytogenetic Map3q24NCBI
AGBL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2949,868,323 - 49,924,290 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11149,888,052 - 49,944,878 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01147,613,564 - 47,669,809 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11148,163,160 - 48,218,611 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1148,163,742 - 48,217,869 (-)Ensemblpanpan1.1panPan2
AGBL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11841,960,085 - 42,003,399 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1841,960,912 - 42,002,255 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1840,691,514 - 40,734,468 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01842,616,043 - 42,658,721 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1842,616,217 - 42,658,118 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11842,104,209 - 42,141,564 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01841,657,442 - 41,700,277 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01842,387,511 - 42,430,423 (+)NCBIUU_Cfam_GSD_1.0
AGBL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl214,933,197 - 14,972,397 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1214,933,188 - 14,971,416 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2216,111,605 - 16,148,424 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AGBL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1117,602,673 - 17,679,431 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl117,603,105 - 17,676,105 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038114,892,707 - 114,994,829 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Agbl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247671,177,563 - 1,190,568 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247671,176,417 - 1,191,550 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000003504   ⟹   ENSSTOP00000003137
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365621,564,607 - 1,593,273 (+)Ensembl
RefSeq Acc Id: XM_021729594   ⟹   XP_021585269
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494719,452,568 - 19,509,105 (+)NCBI
SpeTri2.0NW_0049365621,563,607 - 1,598,451 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040284343   ⟹   XP_040140277
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494719,452,577 - 19,509,105 (+)NCBI
RefSeq Acc Id: XM_040284344   ⟹   XP_040140278
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494719,452,568 - 19,509,105 (+)NCBI
RefSeq Acc Id: XM_040284345   ⟹   XP_040140279
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494719,452,568 - 19,509,105 (+)NCBI
RefSeq Acc Id: XM_040284346   ⟹   XP_040140280
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494719,452,568 - 19,490,290 (+)NCBI
RefSeq Acc Id: XM_040284347   ⟹   XP_040140281
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494719,452,568 - 19,509,105 (+)NCBI
RefSeq Acc Id: XM_040284348   ⟹   XP_040140282
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494719,452,568 - 19,509,105 (+)NCBI
RefSeq Acc Id: XM_040284349   ⟹   XP_040140283
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494719,452,568 - 19,509,092 (+)NCBI
RefSeq Acc Id: XM_040284350   ⟹   XP_040140284
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494719,452,568 - 19,509,092 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021585269   ⟸   XM_021729594
- Peptide Label: isoform X1
- UniProtKB: I3M2E3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040140278   ⟸   XM_040284344
- Peptide Label: isoform X2
- UniProtKB: I3M2E3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140279   ⟸   XM_040284345
- Peptide Label: isoform X3
- UniProtKB: I3M2E3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140281   ⟸   XM_040284347
- Peptide Label: isoform X5
- UniProtKB: I3M2E3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140282   ⟸   XM_040284348
- Peptide Label: isoform X6
- UniProtKB: I3M2E3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140283   ⟸   XM_040284349
- Peptide Label: isoform X7
- UniProtKB: I3M2E3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140284   ⟸   XM_040284350
- Peptide Label: isoform X8
- UniProtKB: I3M2E3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140280   ⟸   XM_040284346
- Peptide Label: isoform X4
- UniProtKB: I3M2E3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140277   ⟸   XM_040284343
- Peptide Label: isoform X1
- UniProtKB: I3M2E3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000003137   ⟸   ENSSTOT00000003504
Protein Domains
Cytosolic carboxypeptidase N-terminal   Peptidase M14 carboxypeptidase A


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000003491 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000003504.3 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.3120 UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro Pepdidase_M14_N UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
NCBI Gene Agbl2 ENTREZGENE
PANTHER CYTOSOLIC CARBOXYPEPTIDASE UniProtKB/TrEMBL
  CYTOSOLIC CARBOXYPEPTIDASE 2 UniProtKB/TrEMBL
Pfam Pepdidase_M14_N UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
Superfamily-SCOP Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt I3M2E3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-02-10 Agbl2  AGBL carboxypeptidase 2  Agbl2  ATP/GTP binding protein like 2  Symbol and/or name change 5135510 APPROVED