Ace2 (angiotensin converting enzyme 2)

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Gene: Ace2 (angiotensin converting enzyme 2) Ictidomys tridecemlineatus

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Symbol:

Ace2

Name:

angiotensin converting enzyme 2

RGD ID:

12475054

Description:

ENCODES a protein that exhibits carboxypeptidase activity (ortholog); metallocarboxypeptidase activity (ortholog); virus receptor activity (ortholog); INVOLVED IN angiotensin maturation (ortholog); maternal process involved in female pregnancy (ortholog); negative regulation of ERK1 and ERK2 cascade (ortholog); PARTICIPATES IN angiotensin (1-7) signaling pathway; renin-angiotensin cascade pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); Acute Lung Injury (ortholog); adult respiratory distress syndrome (ortholog); FOUND IN extracellular region (ortholog); extracellular space (ortholog); plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

angiotensin I converting enzyme 2; angiotensin-converting enzyme 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	4,964,502 - 5,012,706 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	4,965,332 - 5,011,702 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	4,964,526 - 5,011,808 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

abdominal aortic aneurysm (ISO)

Acute Lung Injury (ISO)

adult respiratory distress syndrome (ISO)

Alveolar Bone Loss (ISO)

anxiety disorder (ISO)

autistic disorder (ISO)

avian influenza (ISO)

bacterial pneumonia (ISO)

Cardiac Fibrosis (ISO)

cardiomyopathy (ISO)

Cardiovirus Infections (ISO)

cerebral malaria (ISO)

chemical colitis (ISO)

congestive heart failure (ISO)

Coronary Disease (ISO)

Coronavirus infectious disease (ISO)

COVID-19 (ISO)

Diabetic Cardiomyopathies (ISO)

Diabetic Nephropathies (ISO)

diabetic retinopathy (ISO)

endomyocardial fibrosis (ISO)

Experimental Autoimmune Uveoretinitis (ISO)

Experimental Diabetes Mellitus (ISO)

Experimental Liver Cirrhosis (ISO)

Fanconi anemia (ISO)

focal segmental glomerulosclerosis (ISO)

glaucoma (ISO)

hypertension (ISO)

Hypertensive Nephrosclerosis (ISO)

hypertrophic cardiomyopathy (ISO)

Inflammation (ISO)

Kidney Reperfusion Injury (ISO)

Left Ventricular Hypertrophy (ISO)

lung disease (ISO)

Lung Injury (ISO)

middle cerebral artery infarction (ISO)

multiple congenital anomalies-hypotonia-seizures syndrome 2 (ISO)

myocardial infarction (ISO)

Neurodevelopmental Disorders (ISO)

pancreatic ductal carcinoma (ISO)

Pleural Effusion (ISO)

Pregnancy-Induced Hypertension (ISO)

Prenatal Exposure Delayed Effects (ISO)

primary biliary cholangitis (ISO)

pulmonary fibrosis (ISO)

pulmonary hypertension (ISO)

respiratory syncytial virus infectious disease (ISO)

severe acute respiratory syndrome (ISO)

Spontaneous Abortions (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

thrombosis (ISO)

Ventricular Remodeling (ISO)

Weight Loss (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

angiotensin maturation (ISO)

angiotensin-mediated drinking behavior (IEA)

entry receptor-mediated virion attachment to host cell (IEA)

maternal process involved in female pregnancy (ISO)

negative regulation of ERK1 and ERK2 cascade (ISO)

negative regulation of signaling receptor activity (ISO)

negative regulation of smooth muscle cell proliferation (ISO)

positive regulation of amino acid transport (IEA)

positive regulation of cardiac muscle contraction (IEA)

positive regulation of gap junction assembly (IEA)

positive regulation of L-proline import across plasma membrane (IEA)

proteolysis (IEA)

receptor-mediated virion attachment to host cell (IEA)

regulation of cardiac conduction (IEA)

regulation of systemic arterial blood pressure by renin-angiotensin (IEA)

regulation of transmembrane transporter activity (ISO)

symbiont entry into host cell (IEA,ISO)

tryptophan transport (IEA)

Cellular Component

apical plasma membrane (IEA)

brush border membrane (IEA)

cell projection (IEA)

cell surface (IEA)

cilium (IEA)

cytoplasm (IEA)

extracellular region (IEA,ISO)

extracellular space (IEA,ISO)

membrane (IEA)

plasma membrane (IEA,ISO)

Molecular Function

carboxypeptidase activity (IEA,ISO)

endopeptidase activity (IEA)

identical protein binding (IEA)

metal ion binding (IEA)

metallocarboxypeptidase activity (ISO)

metallopeptidase activity (IEA)

peptidyl-dipeptidase activity (IEA)

protein binding (ISO)

virus receptor activity (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

angiotensin (1-7) signaling pathway (ISO)

renin-angiotensin cascade pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Ace2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	4,964,502 - 5,012,706 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	4,965,332 - 5,011,702 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	4,964,526 - 5,011,808 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ACE2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	15,518,197 - 15,607,211 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	15,494,566 - 15,607,236 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	15,536,320 - 15,625,334 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	15,489,077 - 15,529,058 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	15,338,812 - 15,378,794	NCBI
Celera	X	19,694,648 - 19,735,682 (-)	NCBI		Celera
Cytogenetic Map	X	p22.2	NCBI
HuRef	X	13,333,989 - 13,374,656 (-)	NCBI		HuRef
CHM1_1	X	15,610,102 - 15,651,154 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	15,101,170 - 15,190,203 (-)	NCBI		T2T-CHM13v2.0

Ace2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	162,922,338 - 162,971,414 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	162,922,328 - 162,971,416 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	164,139,342 - 164,188,418 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	164,139,332 - 164,188,420 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	160,577,274 - 160,626,350 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	159,484,737 - 159,532,523 (+)	NCBI		MGSCv36	mm8
Celera	X	147,353,722 - 147,402,904 (+)	NCBI		Celera
Cytogenetic Map	X	F5	NCBI
cM Map	X	76.12	NCBI

Ace2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	33,925,458 - 33,972,851 (-)	NCBI		GRCr8
mRatBN7.2	X	30,293,597 - 30,340,961 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	30,293,589 - 30,340,977 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	31,326,034 - 31,372,619 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	34,763,480 - 34,809,624 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	30,950,895 - 30,996,838 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	32,050,734 - 32,095,860 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	32,049,931 - 32,096,016 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	32,422,286 - 32,469,137 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	51,051,758 - 51,096,036 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	51,105,228 - 51,149,505 (-)	NCBI
Celera	X	30,638,123 - 30,683,403 (-)	NCBI		Celera
Cytogenetic Map	X	q14	NCBI

Ace2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955519	2,591,248 - 2,633,495 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955519	2,591,229 - 2,643,705 (+)	NCBI	ChiLan1.0	ChiLan1.0

ACE2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	17,358,905 - 17,402,027 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	17,362,290 - 17,405,412 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	8,189,267 - 8,229,415 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	15,470,896 - 15,510,891 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	15,470,896 - 15,510,891 (-)	Ensembl	panpan1.1		panPan2

ACE2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	11,798,839 - 11,839,591 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	11,798,839 - 11,900,594 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	11,706,330 - 11,745,360 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	11,760,479 - 11,822,897 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	11,759,554 - 11,789,618 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	11,824,224 - 11,862,960 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	11,818,311 - 11,856,868 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	11,843,799 - 11,882,613 (-)	NCBI		UU_Cfam_GSD_1.0

ACE2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	12,093,242 - 12,151,286 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	12,099,849 - 12,152,204 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	13,061,317 - 13,089,851 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ACE2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	14,032,231 - 14,094,163 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	14,030,233 - 14,077,785 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666056	15,866,608 - 15,915,985 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ace2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624829	344,933 - 391,527 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624829	344,823 - 391,451 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005315994	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040290338	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040290398	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000614	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000006614 ⟹ ENSSTOP00000005914

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936470	4,965,332 - 5,011,702 (-)	Ensembl

RefSeq Acc Id:

XM_005315994 ⟹ XP_005316051

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	4,964,502 - 5,012,706 (-)	NCBI
SpeTri2.0	NW_004936470	4,964,526 - 5,011,808 (-)	NCBI

Sequence:

show sequence

GCCCAACCCAAGTTCAAAGGCTGAAGAGAGAAAAAACTCATGAGGAAATTTTACTCTAGGGAAA
GTTGTTCAGTGGATGGGATCCTGTCCTGGCGCACGGGGAAAGATGTTAGGCTCTTCCTGGCTCC
TTCTCAGCTTTGTTGCTGTGACTGCTGCTCAGTCCACCATCGAGGAACTGGCCAAGACATTTTT
GGACAAGTTTAACCAGGAAGCTGAAGACCTGGATTATCAACGTTCACTTGCTGCTTGGAATTAT
AACACAAATATCACAGAGGAGAATACCCAAAAGATGAATGAGGCTGAGGCCAAATGGTCTGCCT
TTTATGAAGAGCAGTCAAAGCTTGCTACAGCTTATCCACTACAAGAAATTCAAAATTTCACACT
CAAGCGTCAATTGCAGGCCCTTCAGCAGAGTGGGTCTTCAGCGCTCTCCGCCAATAAGAGGGAA
CAGTTGAACACAATTCTAAATACGATGAGCACCATCTACAGTACTGGAAAAGTGTGTAACCCAA
AAAAACCTCAAGAGTGCCTACTACTTGAGCCAGGTTTGGATGAAATAATGGCAAACAGCACCGA
CTACAATGAGAGGCTCTGGGTTTGGGAAGGTTGGAGGTCTGAGGTTGGCAAGCAGCTAAGGCCA
TTATATGAAGAGTACGTGGTCCTGAAAAATGAGATGGCAAGAGCAAACAATTATGAAGACTATG
GGGATTATTGGAGAGGAGATTATGAAGCAGAGGGAGCAGATGGTTATGGCTATAACCGCAACCA
GTTGATTGAAGATGTGGAACGCACATTTGCAGAGATTAAACCATTATATGAACATCTTCATGCT
TATGTGAGAGCAAAGTTGATGAATACCTACCCTTCCTATATCAGTCCAACTGGATGCCTTCCTG
CTCATTTGCTTGGTGATATGTGGGGTAGATTTTGGACAAATCTATACTCTTTGACAGTTCCCTT
TCCAGAGAAACCAAATATAGATGTTACTGATGCAATGATAAACCAGAACTGGAATGCGGTGAGG
ATCTTCAAAGAGGCTGAGAAGTTCTTTGTATCTGTTGGCCTTCCTAATATGACTCAAGGATTCT
GGGAAAACTCCATGTTAACTGAGCCAACAGACGGCCGGAAAGTGGTCTGCCACCCTACAGCTTG
GGATCTACAGAAGGGTGACTTCAGAATCAAGATGTGCACAAAAGTGACAATGGACAACTTCCTG
ACAGCTCATCATGAGATGGGACACATCCAGTATGACATGGCATATGCCATGCAACCTTACCTGC
TAAGAAATGGAGCTAATGAAGGGTTCCATGAAGCTGTTGGGGAAATCATGTCACTGTCTGCAAG
TACACCTAAGCATCTGAAGTCCATTGGTCTTTTGCCATCTGATTTTCGTGAAGACAGTGAAACA
GAAATAAACTTCCTGCTCAAACAAGCACTAACGATTGTTGGAACTCTACCTTTTACTTACATGT
TGGAGAAGTGGAGGTGGATGGTCTTTAAGGGTGAAATTCCCAAAGATCAGTGGATGAAAAAGTG
GTGGGAGATGAAGCGAGAGATAGTTGGGGTGATGGAGCCTGTGCCTCATGACGAAACATACTGT
GACCCCGCAGCTCTATACCATGTTTCTAATGATTTCTCATTCATCCGATATTACACAAGGACCA
TTTATCAATTCCAGTTTCAAGAAGCCCTTTGTCAAGCAGCTAAACATGAAGGCCCCCTCCACAA
ATGTGACATCTCAAATTCCACCGAAGCTGGGCAGAAGCTGCTCAATATGCTGCGTCTTGGAAAG
TCAAAACCCTGGACCTTAGCACTGGAAAATGTGGTAGGAGCAAGGAACATGGACGTAAGACCAC
TGCTCAACTACTTTGAACCATTGTTTGGCTGGCTGAAAGACCAGAACAGGAATTCTTTTGTTGG
GTGGAACACCAACTGGAGCCCTTATACTGACCAAAGCATCAAAGTGAGGATAAGCCTAAAATCA
GCTCTTGGAGAAGAAGCATACCAATGGAATGACAATGAGATGTACTTGTTCCGGTCATCTGTGG
CTTACGCCATGAGAATGTATTTTTCAAAAGTCAAAAACCAGACCATTCCTTTTGGAGAGAAGGA
TGTATGGGTGAGTGATGAGAAACCAAGAATCTCCTTCAACTTCTTTGTCACTGCACCTCAAAAT
GTGTCTGACATTATCCCTAGAACTGATGTTGAAAAGGCTATCAGAATGTCCCGGGGCCGCATCA
ATGGAGTGTTCCGCCTGGATGATAACAGCCTGGAATTCCTGGGGATTCAGCCGACACTTGGACC
TCCTTACCAGCCACCTGTCACCATATGGCTGATTGTTTTTGGAGTTGTGATGGGATTGATAGTG
GTTGGCATTGTCATCCTCATCTTCACTGGGATCAGAGATCGAAGAAGGAAAAATCAAACAAAAC
GAGAAGAAAATCCTTACGCCGAATCCTCCATGGAAATGGGTAAAGGAGAAAATAATCCAGGATA
TCAAAACAATGATGATGTTCAGACTTCATTTTAGAAAAATATTTTTCCTCTTAAGGTGATTTTA
TTGTATGTGCATGTTAATTTCATGGTACCAAAAGTATGAGATTATAAAAATGTTATTAAATATC
AAAACTATGACTCTGTTCAGGAACAAGTGCCCAAAGACATCGTGATTGATTAGTGGGCATCTTC
CCTGACCTTGCTTTCAGTATTTATATTTGTCTCTAAACTTGACTTCTCTTCTGATTTCCGATAG
GAAGGCTGATGTTAGAGTAAAATAGGGAGAGTATGTCTTTGGCCTCACAGGCTAGCTAGAGACG
ATGGAAATGGAAACATTTATTGAGTAATCAGAGTTGGGAAAAAGAAGACTATCATGATAGAGAG
TGTTGGACCTTTATGGAATCTATGCTGTGAGCTGCTGGGGCTGCCAGATTGAGAATGCTACACA
CTGTTCACTTTAATCCAAGTGCCAAAGATAAAGAATGGCACATTTTCTTTACATTAACTTAATC
CAAATACTGCAGTAATTTTCTCAGAGTGATGTTTAGAATGGACCATGCCTTCTTCAGGGTGGCA
TGTCTAACAATGAAAGGAGAAGTCAGAGAACAGTAGAGAATATTATTTTTTCACTTTCAAGCTA
CTTGATCAACATCTCCCTGACAACACAAAACTAGCACAAGGGCCTCCATGAACCTCCAGAGAAT
GTCTGATAGAAACTTGCTTCCTTTGTTCTTTAACTGTAGAGTGAGTGGAAACTCCATCTGAGTG
TTCATCCTGTGAAGTGGATACCCAGTCTCTTAAATCTTTTGTATACCCACTGTATCTGAGAAGT
GCTGAGCACAAAACAGACACGCA

hide sequence

RefSeq Acc Id:

XM_040290338 ⟹ XP_040146272

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	4,964,502 - 5,012,706 (-)	NCBI

RefSeq Acc Id:

XM_040290398 ⟹ XP_040146332

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	4,965,425 - 5,012,706 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005316051	(Get FASTA)	NCBI Sequence Viewer
	XP_040146272	(Get FASTA)	NCBI Sequence Viewer
	XP_040146332	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000005914.3
GenBank Protein	KAG3271719	(Get FASTA)	NCBI Sequence Viewer
	KAG3271720	(Get FASTA)	NCBI Sequence Viewer
	KAG3271721	(Get FASTA)	NCBI Sequence Viewer
	KAG3271722	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005316051 ⟸ XM_005315994
- Peptide Label:	isoform X1
- UniProtKB:	I3M887 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGSCPGARGKMLGSSWLLLSFVAVTAAQSTIEELAKTFLDKFNQEAEDLDYQRSLAAWNYNTNI TEENTQKMNEAEAKWSAFYEEQSKLATAYPLQEIQNFTLKRQLQALQQSGSSALSANKREQLNT ILNTMSTIYSTGKVCNPKKPQECLLLEPGLDEIMANSTDYNERLWVWEGWRSEVGKQLRPLYEE YVVLKNEMARANNYEDYGDYWRGDYEAEGADGYGYNRNQLIEDVERTFAEIKPLYEHLHAYVRA KLMNTYPSYISPTGCLPAHLLGDMWGRFWTNLYSLTVPFPEKPNIDVTDAMINQNWNAVRIFKE AEKFFVSVGLPNMTQGFWENSMLTEPTDGRKVVCHPTAWDLQKGDFRIKMCTKVTMDNFLTAHH EMGHIQYDMAYAMQPYLLRNGANEGFHEAVGEIMSLSASTPKHLKSIGLLPSDFREDSETEINF LLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVMEPVPHDETYCDPAA LYHVSNDFSFIRYYTRTIYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLLNMLRLGKSKPW TLALENVVGARNMDVRPLLNYFEPLFGWLKDQNRNSFVGWNTNWSPYTDQSIKVRISLKSALGE EAYQWNDNEMYLFRSSVAYAMRMYFSKVKNQTIPFGEKDVWVSDEKPRISFNFFVTAPQNVSDI IPRTDVEKAIRMSRGRINGVFRLDDNSLEFLGIQPTLGPPYQPPVTIWLIVFGVVMGLIVVGIV ILIFTGIRDRRRKNQTKREENPYAESSMEMGKGENNPGYQNNDDVQTSF hide sequence

RefSeq Acc Id:	XP_040146272 ⟸ XM_040290338
- Peptide Label:	isoform X1
- UniProtKB:	I3M887 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040146332 ⟸ XM_040290398
- Peptide Label:	isoform X2
- UniProtKB:	I3M887 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSSTOP00000005914 ⟸ ENSSTOT00000006614

Protein Domains

Collectrin-like

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000006588	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000006614.3	UniProtKB/TrEMBL
Gene3D-CATH	1.10.1370.30	UniProtKB/TrEMBL
InterPro	Collectrin_dom	UniProtKB/TrEMBL
	Peptidase_M2	UniProtKB/TrEMBL
NCBI Gene	Ace2	ENTREZGENE
PANTHER	ANGIOTENSIN-CONVERTING ENZYME 2	UniProtKB/TrEMBL
	PTHR10514	UniProtKB/TrEMBL
Pfam	Collectrin	UniProtKB/TrEMBL
	Peptidase_M2	UniProtKB/TrEMBL
PRINTS	PEPDIPTASEA	UniProtKB/TrEMBL
PROSITE	COLLECTRIN_LIKE	UniProtKB/TrEMBL
	PEPTIDASE_M2	UniProtKB/TrEMBL
Superfamily-SCOP	Metalloproteases ('zincins'), catalytic domain	UniProtKB/TrEMBL
UniProt	I3M887	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-01-19	Ace2	angiotensin converting enzyme 2	Ace2	angiotensin I converting enzyme 2	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

RGD Manual Annotations