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ONTOLOGY REPORT - ANNOTATIONS

Term:tryptophan catabolic process
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Accession:GO:0006569 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
Synonyms:exact_synonym: tryptophan breakdown;   tryptophan catabolism;   tryptophan degradation
 narrow_synonym: tryptophan catabolic process, using tryptophanase;   tryptophan catabolism, using tryptophanase


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tryptophan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase IDA RGD PMID:11802786 RGD:70243 NCBI chr13:39,200,412...39,245,954
Ensembl chr13:39,200,314...39,245,209 		JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877 		JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:17356132), (PMID:25767141) RGD PMID:17356132 PMID:25767141 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562 		JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881 		JBrowse link
G Kynu kynureninase involved_in ISO
IEA		 (PMID:17334708)
GO_REF:0000104		 RGD
UniProt		 PMID:17334708 GO_REF:0000104 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kynu kynureninase IDA RGD PMID:7236232 RGD:2303721 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:7236232 GO_REF:0000033, RGD:2303721 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511 		JBrowse link
tryptophan catabolic process to indole-3-acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:32818467), (PMID:32866000) RGD PMID:32818467 PMID:32866000 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562 		JBrowse link
tryptophan catabolic process to kynurenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000041
(PMID:15866519)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:15866519 GO_REF:0000033 GO_REF:0000041 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in
acts_upstream_of_or_within		 IDA
IEA
ISO
IBA		 GO_REF:0000104
(PMID:11751753), (PMID:2419335)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:2419335 PMID:11751753 PMID:10719243 PMID:11513477 GO_REF:0000033 GO_REF:0000104, RGD:2290190, RGD:2290543 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:17671174)
GO_REF:0000104
(PMID:17499941), (PMID:17671174)
GO_REF:0000033
GO_REF:0000041		 RGD
UniProt
GO_Central		 PMID:17499941 PMID:17671174 GO_REF:0000033 GO_REF:0000041 GO_REF:0000104 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324 		JBrowse link
G Kynu kynureninase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:27762317)
GO_REF:0000041		 UniProt
RGD		 PMID:27762317 GO_REF:0000024 GO_REF:0000041 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    metabolic process 11456
      primary metabolic process 10015
        amino acid metabolic process 292
          aromatic amino acid metabolic process 38
            tryptophan metabolic process 12
              tryptophan catabolic process 9
                tryptophan catabolic process to acetyl-CoA 2
                tryptophan catabolic process to catechol 0
                tryptophan catabolic process to indole-3-acetate 1
                tryptophan catabolic process to kynurenine 5
Path 2
Term Annotations click to browse term
  biological_process 19692
    metabolic process 11456
      small molecule metabolic process 1878
        organic acid metabolic process 1021
          oxoacid metabolic process 1010
            carboxylic acid metabolic process 995
              alpha-amino acid metabolic process 210
                alpha-amino acid catabolic process 96
                  tryptophan catabolic process 9
                    tryptophan catabolic process to acetyl-CoA 2
                    tryptophan catabolic process to catechol 0
                    tryptophan catabolic process to indole-3-acetate 1
                    tryptophan catabolic process to kynurenine 5
paths to the root