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ONTOLOGY REPORT - ANNOTATIONS


Term:tryptophan catabolic process
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Accession:GO:0006569 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
Synonyms:exact_synonym: tryptophan breakdown;   tryptophan catabolism;   tryptophan degradation
 narrow_synonym: tryptophan catabolic process, using tryptophanase;   tryptophan catabolism, using tryptophanase


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tryptophan catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase IDA RGD PMID:11802786 RGD:70243 NCBI chr13:44,424,689...44,468,734
Ensembl chr13:44,424,689...44,468,734
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Kmo kynurenine 3-monooxygenase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Kynu kynureninase ISO (PMID:17334708) RGD PMID:17334708 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kynu kynureninase IDA RGD PMID:7236232 RGD:2303721 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:7236232, PMID:21873635 RGD:2303721, RGD:13792537 NCBI chr 2:180,897,059...180,914,919
Ensembl chr 2:180,897,011...180,914,940
JBrowse link
tryptophan catabolic process to kynurenine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase ISO
IBA
IEA
(MGI:MGI:3587527|PMID:15866519)
PMID:21873635
GO_REF:0000041
RGD
UniProt
PMID:15866519, PMID:21873635 GO_REF:0000041, MGI:MGI:3587527, RGD:13792537 NCBI chr10:106,828,963...106,844,314
Ensembl chr10:106,828,981...106,844,314
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 IDA
IBA
ISO
IEA
PMID:21873635
(MGI:MGI:2151782|PMID:2419335), (MGI:MGI:2156954|PMID:11751753)
GO_REF:0000107
RGD
Ensembl
PMID:2419335, PMID:11751753, PMID:10719243, PMID:21873635, PMID:11513477 GO_REF:0000107, MGI:MGI:2151782, MGI:MGI:2156954, RGD:2290190, RGD:13792537, RGD:2290543 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 IEA
IBA
ISO
GO_REF:0000041
PMID:21873635
(MGI:MGI:3712725|PMID:17499941), (MGI:MGI:3719924|PMID:17671174)
(PMID:17671174)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:17499941, PMID:17671174, PMID:21873635 GO_REF:0000041, GO_REF:0000107, MGI:MGI:3712725, MGI:MGI:3719924, RGD:13792537 NCBI chr16:72,232,852...72,291,227
Ensembl chr16:72,268,943...72,289,156
JBrowse link
G Kynu kynureninase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase IEA
ISS
ISO
GO_REF:0000041
GO_REF:0000024
(PMID:27762317)
UniProt
RGD
PMID:27762317 GO_REF:0000024, GO_REF:0000041 NCBI chr 2:180,897,059...180,914,919
Ensembl chr 2:180,897,011...180,914,940
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      primary metabolic process 10941
        cellular amino acid metabolic process 276
          aromatic amino acid family metabolic process 35
            tryptophan metabolic process 11
              tryptophan catabolic process 8
                tryptophan catabolic process to acetyl-CoA 2
                tryptophan catabolic process to catechol 0
                tryptophan catabolic process to indole-3-acetate 0
                tryptophan catabolic process to kynurenine 5
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      nitrogen compound metabolic process 10390
        organonitrogen compound metabolic process 7186
          amine metabolic process 93
            cellular amine metabolic process 85
              cellular biogenic amine metabolic process 48
                indolalkylamine metabolic process 11
                  tryptophan metabolic process 11
                    tryptophan catabolic process 8
                      tryptophan catabolic process to acetyl-CoA 2
                      tryptophan catabolic process to catechol 0
                      tryptophan catabolic process to indole-3-acetate 0
                      tryptophan catabolic process to kynurenine 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.