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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pyrroline
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Accession:CHEBI:23763 term browser browse the term
Definition:Any organic heteromonocyclic compound with a structure based on a dihydropyrrole.
Synonyms:related_synonym: Formula=C4H7N;   dihydropyrrole;   pyrrolines
 xref: CAS:28350-87-0;   Wikipedia:Pyrroline


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pirprofen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases glucuronidation EXP UGT2B1 protein results in increased glucuronidation of pirprofen CTD PMID:8302279 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 multiple interactions ISO pirprofen inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; pirprofen inhibits the reaction [UGT2B7 protein results in increased glucuronidation of Aldosterone] CTD PMID:19740398 NCBI chr14:22,597,103...22,619,968 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19791
    chemical entity 19791
      atom 19788
        nonmetal atom 19663
          nitrogen atom 18540
            nitrogen molecular entity 18540
              organonitrogen compound 18310
                organonitrogen heterocyclic compound 17461
                  pyrroline 2
                    1-(4-fluorophenyl)-3-hydroxy-6,6-dimethyl-3-(trifluoromethyl)-5,7-dihydroindole-2,4-dione 0
                    1-pyrroline 0
                    1-pyrrolinecarboxylic acid + 0
                    1-pyrrolinium + 0
                    2,5-dioxo-1-phenyl-1,4-dihydropyrrolo[1,2-a]quinazoline-3-carbonitrile 0
                    2-(4-fluorophenyl)-4-(4-methoxyanilino)-1-(4-methoxyphenyl)-2H-pyrrol-5-one 0
                    2-[5-(but-3-yn-2-yloxy)-4-chloro-2-fluorophenyl]-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione + 0
                    2-[5-amino-1-(2-methoxyphenyl)-3-oxo-2H-pyrrol-4-yl]-1H-quinazolin-4-one 0
                    2-acetyl-1-pyrroline 0
                    2-methyl-1-(4-methylphenyl)-5-oxo-4-(thiophen-2-ylmethylidene)-3-pyrrolecarboxylic acid ethyl ester 0
                    2-methyl-1-pyrroline 0
                    2-pyrroline 0
                    3,4-dihydro-4-[(5-methyl-2-furanyl)methylene]-2H-pyrrole 0
                    3-[(4-bromophenyl)methylidene]-1-(2-hydroxyphenyl)-5-phenyl-2-pyrrolone 0
                    3-acetyl-5-hydroxy-4,5-dimethyl-1-octyl-2-pyrrolone 0
                    3-phenyl-1,4-dihydropyrrolo[1,2-a]quinazoline-2,5-dione 0
                    3-pyrroline 0
                    4-(2-fluorophenyl)-5-(2-furanylmethyl)-3-(6-oxo-1-cyclohexa-2,4-dienylidene)-2,4-dihydro-1H-pyrrolo[3,4-c]pyrazol-6-one 0
                    4-(3-chlorophenyl)-5-(3-methoxypropyl)-3-(6-oxo-1-cyclohexa-2,4-dienylidene)-2,4-dihydro-1H-pyrrolo[3,4-c]pyrazol-6-one 0
                    4-(3-methoxyanilino)-2-methyl-5-oxo-1-phenyl-2-pyrrolecarboxylic acid ethyl ester 0
                    4-[5-amino-3-oxo-4-(4-oxo-1H-quinazolin-2-yl)-2H-pyrrol-1-yl]benzoic acid ethyl ester 0
                    4-ethyl-2-methoxy-3-phenyl-3,3a,9,9a-tetrahydropyrrolo[2,3-b]quinoxaline 0
                    4-methyl-2-pyrroline-5-carboxylic acid + 0
                    5-(2-furanylmethyl)-4-(3-methoxyphenyl)-3-(6-oxo-1-cyclohexa-2,4-dienylidene)-2,4-dihydro-1H-pyrrolo[3,4-c]pyrazol-6-one 0
                    5-(2-furanylmethylidene)-2-methyl-4-oxo-1-phenyl-3-pyrrolecarboxylic acid methyl ester 0
                    5-[(4-hydroxyphenyl)methylidene]-2-methyl-1-(4-methylphenyl)-4-oxo-3-pyrrolecarboxylic acid methyl ester 0
                    5-amino-2-(3-nitrophenyl)-1-phenyl-2H-pyrrole-3,3,4-tricarbonitrile 0
                    5-amino-4-(1,3-benzothiazol-2-yl)-1-phenyl-2H-pyrrol-3-one 0
                    5-amino-4-(1H-benzimidazol-2-yl)-2,2-dimethyl-1-phenyl-3-pyrrolone 0
                    6-hydroxy-N-methylmyosmine 0
                    Flumiclorac pentyl 0
                    MK-129 0
                    Pulchellalactum 0
                    colibactin 0
                    isotenuazonic acid 0
                    pirprofen 2
                    premycofactocinol 0
                    pristinamycin IIA + 0
                    pyrrolysine + 0
                    trikendiol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19791
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19676
                    p-block element atom 19676
                      carbon group element atom 19579
                        carbon atom 19568
                          organic molecular entity 19568
                            organic molecule 19493
                              organic cyclic compound 19288
                                organic heterocyclic compound 18407
                                  organic heteromonocyclic compound 16448
                                    pyrroline 2
                                      1-(4-fluorophenyl)-3-hydroxy-6,6-dimethyl-3-(trifluoromethyl)-5,7-dihydroindole-2,4-dione 0
                                      1-pyrroline 0
                                      1-pyrrolinecarboxylic acid + 0
                                      1-pyrrolinium + 0
                                      2,5-dioxo-1-phenyl-1,4-dihydropyrrolo[1,2-a]quinazoline-3-carbonitrile 0
                                      2-(4-fluorophenyl)-4-(4-methoxyanilino)-1-(4-methoxyphenyl)-2H-pyrrol-5-one 0
                                      2-[5-(but-3-yn-2-yloxy)-4-chloro-2-fluorophenyl]-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione + 0
                                      2-[5-amino-1-(2-methoxyphenyl)-3-oxo-2H-pyrrol-4-yl]-1H-quinazolin-4-one 0
                                      2-acetyl-1-pyrroline 0
                                      2-methyl-1-(4-methylphenyl)-5-oxo-4-(thiophen-2-ylmethylidene)-3-pyrrolecarboxylic acid ethyl ester 0
                                      2-methyl-1-pyrroline 0
                                      2-pyrroline 0
                                      3,4-dihydro-4-[(5-methyl-2-furanyl)methylene]-2H-pyrrole 0
                                      3-[(4-bromophenyl)methylidene]-1-(2-hydroxyphenyl)-5-phenyl-2-pyrrolone 0
                                      3-acetyl-5-hydroxy-4,5-dimethyl-1-octyl-2-pyrrolone 0
                                      3-phenyl-1,4-dihydropyrrolo[1,2-a]quinazoline-2,5-dione 0
                                      3-pyrroline 0
                                      4-(2-fluorophenyl)-5-(2-furanylmethyl)-3-(6-oxo-1-cyclohexa-2,4-dienylidene)-2,4-dihydro-1H-pyrrolo[3,4-c]pyrazol-6-one 0
                                      4-(3-chlorophenyl)-5-(3-methoxypropyl)-3-(6-oxo-1-cyclohexa-2,4-dienylidene)-2,4-dihydro-1H-pyrrolo[3,4-c]pyrazol-6-one 0
                                      4-(3-methoxyanilino)-2-methyl-5-oxo-1-phenyl-2-pyrrolecarboxylic acid ethyl ester 0
                                      4-[5-amino-3-oxo-4-(4-oxo-1H-quinazolin-2-yl)-2H-pyrrol-1-yl]benzoic acid ethyl ester 0
                                      4-ethyl-2-methoxy-3-phenyl-3,3a,9,9a-tetrahydropyrrolo[2,3-b]quinoxaline 0
                                      4-methyl-2-pyrroline-5-carboxylic acid + 0
                                      5-(2-furanylmethyl)-4-(3-methoxyphenyl)-3-(6-oxo-1-cyclohexa-2,4-dienylidene)-2,4-dihydro-1H-pyrrolo[3,4-c]pyrazol-6-one 0
                                      5-(2-furanylmethylidene)-2-methyl-4-oxo-1-phenyl-3-pyrrolecarboxylic acid methyl ester 0
                                      5-[(4-hydroxyphenyl)methylidene]-2-methyl-1-(4-methylphenyl)-4-oxo-3-pyrrolecarboxylic acid methyl ester 0
                                      5-amino-2-(3-nitrophenyl)-1-phenyl-2H-pyrrole-3,3,4-tricarbonitrile 0
                                      5-amino-4-(1,3-benzothiazol-2-yl)-1-phenyl-2H-pyrrol-3-one 0
                                      5-amino-4-(1H-benzimidazol-2-yl)-2,2-dimethyl-1-phenyl-3-pyrrolone 0
                                      6-hydroxy-N-methylmyosmine 0
                                      Flumiclorac pentyl 0
                                      MK-129 0
                                      Pulchellalactum 0
                                      colibactin 0
                                      isotenuazonic acid 0
                                      pirprofen 2
                                      premycofactocinol 0
                                      pristinamycin IIA + 0
                                      pyrrolysine + 0
                                      trikendiol 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.