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Term:pristinamycin IIA
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Accession:CHEBI:9997 term browser browse the term
Definition:A macrolide that is (together with pristinamycin IA) a component of pristinamycin, an oral streptogramin antibiotic produced by Streptomyces pristinaespiralis. Pristinamycin exhibits bactericidal activity against Gram positive organisms including methicillin-resistant Staphylococcus aureus.
Synonyms:exact_synonym: (3R,4R,5E,10E,12E,14S)-14-hydroxy-3-isopropyl-4,12-dimethyl-8,9,14,15,24,25-hexahydro-1H,3H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
 related_synonym: Formula=C28H35N3O7;   InChI=1S/C28H35N3O7/c1-17(2)26-19(4)9-10-24(34)29-11-5-7-18(3)13-20(32)14-21(33)15-25-30-22(16-37-25)27(35)31-12-6-8-23(31)28(36)38-26/h5,7-10,13,16-17,19-20,26,32H,6,11-12,14-15H2,1-4H3,(H,29,34)/b7-5+,10-9+,18-13+/t19-,20-,26-/m1/s1;   InChIKey=DAIKHDNSXMZDCU-FQTGFAPKSA-N;   Mikamycin A;   Ostreogrycin a;   SMILES=CC(C)[C@H]1OC(=O)C2=CCCN2C(=O)c2coc(CC(=O)C[C@H](O)\\C=C(/C)\\C=C\\CNC(=O)\\C=C\\[C@H]1C)n2;   Streptogramin A;   Virginiamycin M1;   Virginiamycin factor M1
 alt_id: CHEBI:46395
 xref: CAS:21411-53-0 "ChemIDplus";   CAS:21411-53-0 "KEGG COMPOUND";   DrugBank:DB01669;   KEGG:C11299;   PDBeChem:VIR;   PMID:15480455 "Europe PMC";   PMID:24324222 "Europe PMC";   PMID:24687494 "Europe PMC";   PMID:25223995 "Europe PMC";   PMID:3096930 "Europe PMC";   PMID:5905315 "Europe PMC";   Reaxys:71867 "Reaxys";   Wikipedia:Pristinamycin_IIA

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Term Annotations click to browse term
  CHEBI ontology 19734
    role 19680
      biological role 19678
        antimicrobial agent 17216
          macrolide antibiotic 324
            pristinamycin IIA 0
              virginiamycin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19734
    subatomic particle 19730
      composite particle 19730
        hadron 19730
          baryon 19730
            nucleon 19730
              atomic nucleus 19730
                atom 19730
                  main group element atom 19614
                    p-block element atom 19614
                      carbon group element atom 19506
                        carbon atom 19500
                          organic molecular entity 19500
                            organic group 18414
                              organic divalent group 18406
                                organodiyl group 18406
                                  carbonyl group 18295
                                    carbonyl compound 18295
                                      carboxylic acid 17963
                                        carboacyl group 17074
                                          univalent carboacyl group 17074
                                            carbamoyl group 16804
                                              carboxamide 16804
                                                alpha,beta-unsaturated carboxylic acid amide 4760
                                                  enamide 4760
                                                    pristinamycin IIA 0
                                                      virginiamycin 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.