rac-1-monopalmitoylglycerol - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	rac-1-monopalmitoylglycerol	go back to main search page
Accession:	CHEBI:75811	browse the term
Definition:	A rac-1-monoacylglycerol in which the acyl group is palmitoyl.
Synonyms:	exact_synonym:	rac-2,3-dihydroxypropyl palmitate
	related_synonym:	(+-)--glycerol 1-palmitate; (+-)-1-monopalmitoylglycerol; (+-)-2,3-dihydroxypropyl palmitate; (+-)-alpha-monopalmitin; (+-)-glycerol 1-monopalmitate; (+-)-glyceryl palmitate; (+-)-palmitic acid alpha-monoglyceride; 1-hexadecanoyl-rac-glycerol; Formula=C19H38O4; InChI=1S/C19H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(22)23-17-18(21)16-20/h18,20-21H,2-17H2,1H3; InChIKey=QHZLMUACJMDIAE-UHFFFAOYSA-N; MG(16:0/0:0/0:0)[rac]; SMILES=CCCCCCCCCCCCCCCC(=O)OCC(O)CO; rac-2,3-dihydroxypropyl hexadecanoate; rac-alpha-monopalmitin; rac-glycerol 1-monopalmitate; rac-glycerol 1-palmitate; rac-glyceryl palmitate; rac-palmitic acid alpha-monoglyceride
	xref:	CAS:542-44-9; HMDB:HMDB0031074; LIPID_MAPS_instance:LMGL01010001
	xref_mesh:	MESH:C027735
	xref:	MetaCyc:CPD-8508; PMID:4455214; Reaxys:1728235

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Genes (14)

rac-1-monopalmitoylglycerol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

AKT serine/threonine kinase 1

increases phosphorylation

palmitoyl glycerol results in increased phosphorylation of AKT1 protein

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

baculoviral IAP repeat-containing 2

decreases expression

palmitoyl glycerol results in decreased expression of BIRC2 protein

NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732

G

baculoviral IAP repeat-containing 3

decreases expression

palmitoyl glycerol results in decreased expression of BIRC3 protein

NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802

G

baculoviral IAP repeat-containing 5

decreases expression

palmitoyl glycerol results in decreased expression of BIRC5 protein

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

G

caspase 3

multiple interactions

palmitoyl glycerol results in decreased expression of and results in increased cleavage of CASP3 protein

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

cyclin D1

decreases expression

palmitoyl glycerol results in decreased expression of CCND1 protein

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin-dependent kinase inhibitor 1A

increases expression

palmitoyl glycerol results in increased expression of CDKN1A protein

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

microtubule-associated protein 1 light chain 3 beta

increases lipidation
multiple interactions

palmitoyl glycerol results in increased lipidation of MAP1LC3B protein
Chloroquine promotes the reaction [palmitoyl glycerol results in increased lipidation of MAP1LC3B protein]

NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690

G

poly (ADP-ribose) polymerase 1

multiple interactions

palmitoyl glycerol results in decreased expression of and results in increased cleavage of PARP1 protein

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

phosphoinositide-3-kinase regulatory subunit 1

affects phosphorylation

palmitoyl glycerol affects the phosphorylation of PIK3R1 protein

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

G

receptor interacting serine/threonine kinase 1

decreases expression

palmitoyl glycerol results in decreased expression of RIPK1 protein

NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824

G

receptor-interacting serine-threonine kinase 3

decreases expression

palmitoyl glycerol results in decreased expression of RIPK3 protein

NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121

G

sequestosome 1

decreases expression

palmitoyl glycerol results in decreased expression of SQSTM1 protein

NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673

G

X-linked inhibitor of apoptosis

decreases expression

palmitoyl glycerol results in decreased expression of XIAP protein

NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19898
role	19868
biological role	19866
biochemical role	19571
metabolite	19558
3-palmitoyl-sn-glycerol	14
rac-1-monopalmitoylglycerol	14
Path 2
Term	Annotations
CHEBI ontology	19898
subatomic particle	19896
composite particle	19896
hadron	19896
baryon	19896
nucleon	19896
atomic nucleus	19896
atom	19896
main group element atom	19835
p-block element atom	19835
carbon group element atom	19774
carbon atom	19771
organic molecular entity	19771
heteroorganic entity	19528
organochalcogen compound	19290
organooxygen compound	19206
carbohydrates and carbohydrate derivatives	15297
carbohydrate	15297
alditol	3308
glycerol	3186
glycerolipid	1793
glyceride	1639
monoacylglycerol	1593
1-monoglyceride	15
1-acylglycerol 16:0	14
1-monopalmitoylglycerol	14
3-palmitoyl-sn-glycerol	14
rac-1-monopalmitoylglycerol	14

paths to the root