rac-1-monopalmitoylglycerol - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	rac-1-monopalmitoylglycerol	go back to main search page
Accession:	CHEBI:75811	browse the term
Definition:	A rac-1-monoacylglycerol in which the acyl group is palmitoyl.
Synonyms:	exact_synonym:	rac-2,3-dihydroxypropyl palmitate
	related_synonym:	(+-)--glycerol 1-palmitate; (+-)-1-monopalmitoylglycerol; (+-)-2,3-dihydroxypropyl palmitate; (+-)-alpha-monopalmitin; (+-)-glycerol 1-monopalmitate; (+-)-glyceryl palmitate; (+-)-palmitic acid alpha-monoglyceride; 1-hexadecanoyl-rac-glycerol; Formula=C19H38O4; InChI=1S/C19H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(22)23-17-18(21)16-20/h18,20-21H,2-17H2,1H3; InChIKey=QHZLMUACJMDIAE-UHFFFAOYSA-N; MG(16:0/0:0/0:0)[rac]; SMILES=CCCCCCCCCCCCCCCC(=O)OCC(O)CO; rac-2,3-dihydroxypropyl hexadecanoate; rac-alpha-monopalmitin; rac-glycerol 1-monopalmitate; rac-glycerol 1-palmitate; rac-glyceryl palmitate; rac-palmitic acid alpha-monoglyceride
	xref:	CAS:542-44-9; HMDB:HMDB0031074; LIPID_MAPS_instance:LMGL01010001
	xref_mesh:	MESH:C027735
	xref:	MetaCyc:CPD-8508; PMID:4455214; Reaxys:1728235

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Genes (14)

rac-1-monopalmitoylglycerol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

AKT serine/threonine kinase 1

increases phosphorylation

palmitoyl glycerol results in increased phosphorylation of AKT1 protein

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

baculoviral IAP repeat-containing 2

decreases expression

palmitoyl glycerol results in decreased expression of BIRC2 protein

NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732

G

baculoviral IAP repeat-containing 3

decreases expression

palmitoyl glycerol results in decreased expression of BIRC3 protein

NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802

G

baculoviral IAP repeat-containing 5

decreases expression

palmitoyl glycerol results in decreased expression of BIRC5 protein

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

G

caspase 3

multiple interactions

palmitoyl glycerol results in decreased expression of and results in increased cleavage of CASP3 protein

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

cyclin D1

decreases expression

palmitoyl glycerol results in decreased expression of CCND1 protein

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin-dependent kinase inhibitor 1A

increases expression

palmitoyl glycerol results in increased expression of CDKN1A protein

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

microtubule-associated protein 1 light chain 3 beta

increases lipidation
multiple interactions

palmitoyl glycerol results in increased lipidation of MAP1LC3B protein
Chloroquine promotes the reaction [palmitoyl glycerol results in increased lipidation of MAP1LC3B protein]

NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690

G

poly (ADP-ribose) polymerase 1

multiple interactions

palmitoyl glycerol results in decreased expression of and results in increased cleavage of PARP1 protein

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

phosphoinositide-3-kinase regulatory subunit 1

affects phosphorylation

palmitoyl glycerol affects the phosphorylation of PIK3R1 protein

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

G

receptor interacting serine/threonine kinase 1

decreases expression

palmitoyl glycerol results in decreased expression of RIPK1 protein

NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824

G

receptor-interacting serine-threonine kinase 3

decreases expression

palmitoyl glycerol results in decreased expression of RIPK3 protein

NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121

G

sequestosome 1

decreases expression

palmitoyl glycerol results in decreased expression of SQSTM1 protein

NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673

G

X-linked inhibitor of apoptosis

decreases expression

palmitoyl glycerol results in decreased expression of XIAP protein

NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19840
role	19816
biological role	19814
biochemical role	19524
metabolite	19511
3-palmitoyl-sn-glycerol	14
rac-1-monopalmitoylglycerol	14
Path 2
Term	Annotations
CHEBI ontology	19840
subatomic particle	19838
composite particle	19838
hadron	19838
baryon	19838
nucleon	19838
atomic nucleus	19838
atom	19838
main group element atom	19788
p-block element atom	19788
carbon group element atom	19734
carbon atom	19730
organic molecular entity	19730
heteroorganic entity	19485
organochalcogen compound	19247
organooxygen compound	19165
carbohydrates and carbohydrate derivatives	15290
carbohydrate	15290
alditol	3300
glycerol	3179
glycerolipid	1786
glyceride	1638
monoacylglycerol	1592
1-monoglyceride	15
1-acylglycerol 16:0	14
1-monopalmitoylglycerol	14
3-palmitoyl-sn-glycerol	14
rac-1-monopalmitoylglycerol	14

paths to the root