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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1-monopalmitoylglycerol
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Accession:CHEBI:69081 term browser browse the term
Definition:A 1-monoglyceride that has palmitoyl as the acyl group. A natural product found in Neolitsea daibuensis.
Synonyms:exact_synonym: 2,3-dihydroxypropyl palmitate
 related_synonym: 1-hexadecanoylglycerol;   1-palmitoylglycerol;   2,3-dihydroxypropyl hexadecanoate;   Formula=C19H38O4;   InChI=1S/C19H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(22)23-17-18(21)16-20/h18,20-21H,2-17H2,1H3;   InChIKey=QHZLMUACJMDIAE-UHFFFAOYSA-N;   SMILES=CCCCCCCCCCCCCCCC(=O)OCC(O)CO;   alpha-monopalmitin;   glycerol 1-monopalmitate;   glycerol 1-palmitate;   glycerol 3-palmitate;   glyceryl palmitate;   hexadecanoic acid, 2,3-dihydroxypropyl ester;   palmitic acid alpha-monoglyceride;   palmitin, 1-mono
 xref: CAS:542-44-9;   HMDB:HMDB0031074;   LINCS:LSM-4482
 xref_mesh: MESH:C027735
 xref: MetaCyc:CPD-8508;   PMID:15357000;   PMID:22148193;   Reaxys:1728235



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1-monopalmitoylglycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO palmitoyl glycerol results in increased phosphorylation of AKT1 protein CTD PMID:37466199 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO palmitoyl glycerol results in decreased expression of BIRC2 protein CTD PMID:37466199 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO palmitoyl glycerol results in decreased expression of BIRC3 protein CTD PMID:37466199 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO palmitoyl glycerol results in decreased expression of BIRC5 protein CTD PMID:37466199 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Casp3 caspase 3 multiple interactions ISO palmitoyl glycerol results in decreased expression of and results in increased cleavage of CASP3 protein CTD PMID:37466199 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO palmitoyl glycerol results in decreased expression of CCND1 protein CTD PMID:37466199 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO palmitoyl glycerol results in increased expression of CDKN1A protein CTD PMID:37466199 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases lipidation
multiple interactions
ISO palmitoyl glycerol results in increased lipidation of MAP1LC3B protein
Chloroquine promotes the reaction [palmitoyl glycerol results in increased lipidation of MAP1LC3B protein]
CTD PMID:37466199 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO palmitoyl glycerol results in decreased expression of and results in increased cleavage of PARP1 protein CTD PMID:37466199 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 affects phosphorylation ISO palmitoyl glycerol affects the phosphorylation of PIK3R1 protein CTD PMID:37466199 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 decreases expression ISO palmitoyl glycerol results in decreased expression of RIPK1 protein CTD PMID:37466199 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 decreases expression ISO palmitoyl glycerol results in decreased expression of RIPK3 protein CTD PMID:37466199 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
JBrowse link
G Sqstm1 sequestosome 1 decreases expression ISO palmitoyl glycerol results in decreased expression of SQSTM1 protein CTD PMID:37466199 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO palmitoyl glycerol results in decreased expression of XIAP protein CTD PMID:37466199 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
rac-1-monopalmitoylglycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO palmitoyl glycerol results in increased phosphorylation of AKT1 protein CTD PMID:37466199 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO palmitoyl glycerol results in decreased expression of BIRC2 protein CTD PMID:37466199 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO palmitoyl glycerol results in decreased expression of BIRC3 protein CTD PMID:37466199 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO palmitoyl glycerol results in decreased expression of BIRC5 protein CTD PMID:37466199 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Casp3 caspase 3 multiple interactions ISO palmitoyl glycerol results in decreased expression of and results in increased cleavage of CASP3 protein CTD PMID:37466199 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO palmitoyl glycerol results in decreased expression of CCND1 protein CTD PMID:37466199 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO palmitoyl glycerol results in increased expression of CDKN1A protein CTD PMID:37466199 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases lipidation
multiple interactions
ISO palmitoyl glycerol results in increased lipidation of MAP1LC3B protein
Chloroquine promotes the reaction [palmitoyl glycerol results in increased lipidation of MAP1LC3B protein]
CTD PMID:37466199 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO palmitoyl glycerol results in decreased expression of and results in increased cleavage of PARP1 protein CTD PMID:37466199 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 affects phosphorylation ISO palmitoyl glycerol affects the phosphorylation of PIK3R1 protein CTD PMID:37466199 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 decreases expression ISO palmitoyl glycerol results in decreased expression of RIPK1 protein CTD PMID:37466199 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 decreases expression ISO palmitoyl glycerol results in decreased expression of RIPK3 protein CTD PMID:37466199 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
JBrowse link
G Sqstm1 sequestosome 1 decreases expression ISO palmitoyl glycerol results in decreased expression of SQSTM1 protein CTD PMID:37466199 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO palmitoyl glycerol results in decreased expression of XIAP protein CTD PMID:37466199 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link

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Path 1
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  CHEBI ontology 19838
    role 19810
      biological role 19808
        biochemical role 19543
          metabolite 19506
            eukaryotic metabolite 19330
              plant metabolite 17968
                1-monopalmitoylglycerol 14
                  1-hexadecanoyl-sn-glycerol + 14
                  3-palmitoyl-sn-glycerol + 14
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19782
                    p-block element atom 19782
                      carbon group element atom 19722
                        carbon atom 19719
                          organic molecular entity 19719
                            heteroorganic entity 19474
                              organochalcogen compound 19262
                                organooxygen compound 19153
                                  carbohydrates and carbohydrate derivatives 15270
                                    carbohydrate 15270
                                      alditol 3296
                                        glycerol 3179
                                          glycerolipid 1786
                                            glyceride 1638
                                              monoacylglycerol 1592
                                                1-monoglyceride 15
                                                  1-acylglycerol 16:0 14
                                                    1-monopalmitoylglycerol 14
                                                      1-hexadecanoyl-sn-glycerol + 14
                                                      3-palmitoyl-sn-glycerol + 14
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