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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:glycerolipid
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Accession:CHEBI:35741 term browser browse the term
Definition:Any member of the group of lipids containing a common glycerol backbone to which at least one fatty acid-derived group is attached.
Synonyms:related_synonym: glycerolipids
 xref: PMID:18606873


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1,2,3-trilinolenoylglycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO trilinolenin results in decreased expression of ABCA1 mRNA CTD PMID:18356535 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 decreases expression ISO trilinolenin results in decreased expression of ABCG5 mRNA CTD PMID:18356535 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 decreases expression ISO trilinolenin results in decreased expression of ABCG8 mRNA CTD PMID:18356535 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression ISO trilinolenin results in decreased expression of CYP27A1 mRNA CTD PMID:18356535 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO trilinolenin results in increased expression of HMGCR mRNA CTD PMID:18356535 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Mttp microsomal triglyceride transfer protein increases expression ISO trilinolenin results in increased expression of MTTP mRNA CTD PMID:18356535 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239 		JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 decreases expression ISO trilinolenin results in decreased expression of NPC1L1 mRNA CTD PMID:18356535 NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113 		JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO trilinolenin results in decreased expression of SCD1 mRNA CTD PMID:8729090 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
1,2,3-trilinoleoylglycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO trilinolein results in decreased expression of ABCA1 mRNA CTD PMID:18356535 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 decreases expression ISO trilinolein results in decreased expression of ABCG5 mRNA CTD PMID:18356535 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 decreases expression ISO trilinolein results in decreased expression of ABCG8 mRNA CTD PMID:18356535 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression ISO trilinolein results in decreased expression of CYP27A1 mRNA CTD PMID:18356535 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO trilinolein results in increased expression of HMGCR mRNA CTD PMID:18356535 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Mttp microsomal triglyceride transfer protein increases expression ISO trilinolein results in increased expression of MTTP mRNA CTD PMID:18356535 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239 		JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 decreases expression ISO trilinolein results in decreased expression of NPC1L1 mRNA CTD PMID:18356535 NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113 		JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions
decreases expression		 ISO Clofibrate inhibits the reaction [trilinolein results in decreased expression of SCD1 mRNA] CTD PMID:8790349 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
1,2-dibutyrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il4 interleukin 4 multiple interactions ISO [dibutyrylglycerol analog co-treated with Fluorescein-5-isothiocyanate] affects the secretion of IL4 protein CTD PMID:29198882 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO dibutyrylglycerol analog results in increased activity of TRPA1 protein CTD PMID:29198882 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570 		JBrowse link
1,2-didecanoylglycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnlip pancreatic lipase increases metabolic processing ISO PNLIP protein results in increased metabolism of 1,2-didecanoylglycerol CTD PMID:9822688 NCBI chr 1:257,774,012...257,811,656
Ensembl chr 1:257,798,581...257,811,654 		JBrowse link
G Pnliprp2 pancreatic lipase related protein 2 increases metabolic processing EXP PNLIPRP2 protein results in increased metabolism of 1,2-didecanoylglycerol CTD PMID:9822688 NCBI chr 1:257,897,766...257,916,434
Ensembl chr 1:257,897,766...257,916,434 		JBrowse link
G Sprr1a small proline-rich protein 1A increases expression ISO 1,2-didecanoylglycerol results in increased expression of SPRR1A protein CTD PMID:8617999 NCBI chr 2:178,055,096...178,057,012
Ensembl chr 2:178,055,096...178,057,063 		JBrowse link
1,2-dihexadecanoyl-sn-glycero-3-phosphocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 multiple interactions ISO 1,2-Dipalmitoylphosphatidylcholine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein] CTD PMID:19041333 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Prnp prion protein multiple interactions
affects folding		 ISO Copper affects the reaction [1,2-Dipalmitoylphosphatidylcholine affects the folding of PRNP protein modified form] CTD PMID:20936829 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937 		JBrowse link
1,2-dioctanoyl-sn-glycero-3-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO dioctanoylphosphatidic acid results in increased expression of PTGS2 protein CTD PMID:11854442 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fech ferrochelatase affects abundance ISO FECH protein affects the abundance of 1-palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine CTD PMID:29906468 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fech ferrochelatase affects abundance ISO FECH protein affects the abundance of 1-palmitoyl-2-linoleoylphosphatidylcholine CTD PMID:29906468 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
1-monolauroylglycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iyd iodotyrosine deiodinase multiple interactions ISO 1-monomyristin inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319 		JBrowse link
1-O-oleoyl-sn-glycero-3-phosphocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 multiple interactions ISO [NR5A2 gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of 1-oleoyl lysophosphatidylcholine CTD PMID:29515023 NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326 		JBrowse link
G Smad3 SMAD family member 3 decreases abundance ISO SMAD3 protein results in decreased abundance of 1-oleoyl lysophosphatidylcholine CTD PMID:23034213 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a increases expression ISO 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased expression of AGTR1 mRNA CTD PMID:16386258 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase increases expression ISO 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased expression of ALOX5 mRNA CTD PMID:16386258 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression ISO 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased expression of CCR2 mRNA CTD PMID:16386258 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Cd68 Cd68 molecule increases expression ISO 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased expression of CD68 mRNA CTD PMID:16386258 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697 		JBrowse link
G Crp C-reactive protein increases expression ISO 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased expression of CRP mRNA CTD PMID:16386258 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
increases phosphorylation		 EXP AG 1879 inhibits the reaction [1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased phosphorylation of GJA1 protein]; resveratrol inhibits the reaction [1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased phosphorylation of GJA1 protein] CTD PMID:24079413 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Il1a interleukin 1 alpha increases expression ISO 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased expression of IL1A mRNA CTD PMID:16386258 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased expression of IL1B mRNA CTD PMID:16386258 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Kcnab2 potassium voltage-gated channel subfamily A regulatory beta subunit 2 multiple interactions EXP [KCNAB2 protein co-treated with NADP] results in increased reduction of 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine CTD PMID:21296056 NCBI chr 5:162,899,511...162,988,057
Ensembl chr 5:162,901,896...162,988,243 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions		 EXP 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased phosphorylation of MAPK1 protein
resveratrol inhibits the reaction [1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased phosphorylation of MAPK1 protein]		 CTD PMID:24079413 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation		 EXP resveratrol inhibits the reaction [1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased phosphorylation of MAPK3 protein] CTD PMID:24079413 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 increases expression ISO 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased expression of OLR1 mRNA CTD PMID:16386258 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523 		JBrowse link
G Ptafr platelet-activating factor receptor affects binding
multiple interactions		 ISO 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine binds to PTAFR protein
1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine inhibits the reaction [Platelet Activating Factor binds to PTAFR protein]		 CTD PMID:16386258 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 increases expression ISO 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased expression of PTGS1 mRNA CTD PMID:16386258 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased expression of PTGS2 mRNA CTD PMID:16386258 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Sele selectin E increases expression
increases secretion		 ISO 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased expression of SELE mRNA
1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased secretion of SELE protein		 CTD PMID:16386258 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions
increases phosphorylation		 EXP resveratrol inhibits the reaction [1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased phosphorylation of SRC protein] CTD PMID:24079413 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 increases expression ISO 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased expression of TIMP4 mRNA CTD PMID:16386258 NCBI chr 4:148,306,021...148,312,558
Ensembl chr 4:148,304,490...148,312,558 		JBrowse link
G Tnf tumor necrosis factor increases expression
increases secretion		 ISO 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased expression of TNF mRNA
1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased secretion of TNF protein		 CTD PMID:16386258 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
1-octadec-9-enoylglycero-3-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle increases expression
multiple interactions		 ISO lysophosphatidic acid results in increased expression of ACTA2 mRNA
N-(4-chlorophenyl)-1-((3-(furan-2-yl)phenyl)carbonyl)piperidine-3-carboxamide inhibits the reaction [lysophosphatidic acid results in increased expression of ACTA2 mRNA]		 CTD PMID:24706986 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation		 ISO
EXP		 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of AKT1 protein]; Resveratrol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of AKT1 protein]
1-Butanol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of AKT1 protein]; exoenzyme C3, Clostridium botulinum inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of AKT1 protein]		 CTD PMID:14769825 PMID:17550345 PMID:20103642 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions ISO ALOX5 protein promotes the reaction [lysophosphatidic acid results in increased abundance of Hydrogen Peroxide]; Masoprocol inhibits the reaction [ALOX5 protein promotes the reaction [lysophosphatidic acid results in increased abundance of Hydrogen Peroxide]]; zileuton inhibits the reaction [ALOX5 protein promotes the reaction [lysophosphatidic acid results in increased abundance of Hydrogen Peroxide]] CTD PMID:10698703 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO [Lithocholic Acid co-treated with lysophosphatidic acid] results in increased activity of ALPL protein CTD PMID:19646460 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member increases phosphorylation ISO lysophosphatidic acid results in increased phosphorylation of BCAR1 protein CTD PMID:11792571 NCBI chr19:39,679,218...39,713,952
Ensembl chr19:39,679,204...39,713,907 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression ISO lysophosphatidic acid analog results in increased expression of BCL2 protein; lysophosphatidic acid results in increased expression of BCL2 protein CTD PMID:23251428 NCBI chr13:22,689,783...22,853,920 JBrowse link
G C5 complement C5 increases expression ISO lysophosphatidic acid results in increased expression of HC protein CTD PMID:25822713 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO lysophosphatidic acid analog inhibits the reaction [cobaltous chloride results in increased activity of CASP3 protein]; lysophosphatidic acid inhibits the reaction [cobaltous chloride results in increased activity of CASP3 protein] CTD PMID:23251428 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ccl12 C-C motif chemokine ligand 12 increases expression
multiple interactions		 ISO lysophosphatidic acid results in increased expression of CCL12 protein
3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of CCL12 protein]		 CTD PMID:25822713 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780 		JBrowse link
G Ccl28 C-C motif chemokine ligand 28 multiple interactions
increases expression		 ISO 3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of CCL28 protein] CTD PMID:25822713 NCBI chr 2:51,601,354...51,625,999
Ensembl chr 2:51,601,331...51,625,997 		JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions
increases expression		 ISO 3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of CCN1 protein] CTD PMID:25822713 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Ccn2 cellular communication network factor 2 increases expression
multiple interactions		 EXP
ISO		 lysophosphatidic acid results in increased expression of CCN2 protein
N-(4-chlorophenyl)-1-((3-(furan-2-yl)phenyl)carbonyl)piperidine-3-carboxamide inhibits the reaction [lysophosphatidic acid results in increased expression of CCN2 mRNA]
Simvastatin inhibits the reaction [lysophosphatidic acid results in increased expression of CCN2 protein]; Y 27632 inhibits the reaction [lysophosphatidic acid results in increased expression of CCN2 protein]		 CTD PMID:15200425 PMID:24706986 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression
multiple interactions		 ISO lysophosphatidic acid results in increased expression of COL1A2 mRNA
N-(4-chlorophenyl)-1-((3-(furan-2-yl)phenyl)carbonyl)piperidine-3-carboxamide inhibits the reaction [lysophosphatidic acid results in increased expression of COL1A2 mRNA]		 CTD PMID:24706986 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Csf1 colony stimulating factor 1 increases expression ISO lysophosphatidic acid results in increased expression of CSF1 protein CTD PMID:25822713 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression
multiple interactions		 ISO lysophosphatidic acid results in increased expression of CXCL12 protein
3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of CXCL12 protein]		 CTD PMID:25822713 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl16 C-X-C motif chemokine ligand 16 increases expression
multiple interactions		 ISO lysophosphatidic acid results in increased expression of CXCL16 protein
3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of CXCL16 protein]		 CTD PMID:25822713 NCBI chr10:55,166,721...55,171,316
Ensembl chr10:55,166,723...55,171,592 		JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 multiple interactions
decreases expression		 ISO lysophosphatidic acid inhibits the reaction [CXCR1 protein binds to LPAR1 protein]; lysophosphatidic acid results in decreased expression of [CXCR1 protein binds to LPAR1 protein]
lysophosphatidic acid results in decreased expression of CXCR1 mRNA		 CTD PMID:16224106 NCBI chr 9:75,768,124...75,771,122
Ensembl chr 9:75,766,770...75,771,084 		JBrowse link
G Dgka diacylglycerol kinase, alpha multiple interactions ISO DGKA protein promotes the reaction [lysophosphatidic acid results in increased activity of PIP5K1A protein] CTD PMID:10913605 NCBI chr 7:1,148,734...1,175,324
Ensembl chr 7:1,148,735...1,175,110 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases phosphorylation		 ISO GNA13 mutant form inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EGFR protein]; Pertussis Toxin inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EGFR protein]; resveratrol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EGFR protein] CTD PMID:23127547 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
increases phosphorylation		 EXP 1-Butanol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EIF4EBP1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EIF4EBP1 protein]; 2-butanol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EIF4EBP1 protein]; exoenzyme C3, Clostridium botulinum inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:14769825 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 multiple interactions
decreases expression		 ISO
EXP		 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; 3-(2-methoxybenzylamino)-2-phenylpiperidine inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; [[Capsaicin results in increased chemical synthesis of Lysophosphatidylcholines] which results in increased secretion of Lysophosphatidylcholines] promotes the reaction [ENPP2 results in increased chemical synthesis of lysophosphatidic acid]; [[ONO-8430506 results in decreased activity of ENPP2 protein] which results in decreased abundance of lysophosphatidic acid] which results in decreased expression of NFE2L2; [[ONO-8430506 results in decreased activity of ENPP2 protein] which results in decreased chemical synthesis of and results in decreased abundance of lysophosphatidic acid] which results in increased expression of ENPP2 mRNA; [ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid; [ENPP2 protein co-treated with Lysophosphatidylcholines] results in increased chemical synthesis of lysophosphatidic acid; [ONO-8430506 results in decreased activity of ENPP2 protein] which results in decreased abundance of lysophosphatidic acid; [ONO-8430506 results in decreased activity of ENPP2 protein] which results in decreased chemical synthesis of and results in decreased abundance of lysophosphatidic acid; arachidonyltrifluoromethane inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; bisindolylmaleimide I inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; Dizocilpine Maleate inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; IL1B protein inhibits the reaction [lysophosphatidic acid results in decreased expression of ENPP2 protein]; TNF protein inhibits the reaction [lysophosphatidic acid results in decreased expression of ENPP2 protein]; U 0126 inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; xestospongin C inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]
lysophosphatidic acid inhibits the reaction [ENPP2 mutant form results in decreased expression of MBP mRNA]		 CTD PMID:18594965 PMID:19014389 PMID:24599971 PMID:24747415 PMID:25398768 More... NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827 		JBrowse link
G Epo erythropoietin multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of GYPA mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; WP1066 inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein] CTD PMID:21915944 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Gata1 GATA binding protein 1 multiple interactions ISO [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA] CTD PMID:21915944 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530 		JBrowse link
G Gna13 G protein subunit alpha 13 multiple interactions ISO GNA13 mutant form inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EGFR protein] CTD PMID:23127547 NCBI chr10:94,337,939...94,370,774
Ensembl chr10:94,337,725...94,370,774 		JBrowse link
G Gypa glycophorin A multiple interactions ISO lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of GYPA mRNA] CTD PMID:21915944 NCBI chr19:27,450,311...27,465,940
Ensembl chr19:27,450,308...27,465,822 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression		 ISO L-4F peptide inhibits the reaction [lysophosphatidic acid results in increased expression of HIF1A protein]; resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of HIF1A protein]
[lysophosphatidic acid results in increased expression of HIF1A protein] which results in increased expression of VEGFA mRNA; [lysophosphatidic acid results in increased expression of HIF1A protein] which results in increased expression of VEGFA protein; lysophosphatidic acid results in increased expression of HIF1A protein		 CTD PMID:17919812 PMID:22537771 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions
increases phosphorylation		 EXP MK2i peptide inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of HSPB1 protein]; SB 203580 inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of HSPB1 protein] CTD PMID:20864298 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO IL1B protein inhibits the reaction [lysophosphatidic acid results in decreased expression of ENPP2 protein] CTD PMID:25896349 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 increases secretion ISO lysophosphatidic acid results in increased secretion of IL6 protein CTD PMID:21821728 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer multiple interactions
increases expression		 ISO 3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of IL6ST protein] CTD PMID:25822713 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Kitlg KIT ligand multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of GYPA mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; WP1066 inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein] CTD PMID:21915944 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Kng2 kininogen 2 multiple interactions EXP KNG1 protein inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein] CTD PMID:10537051 NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971 		JBrowse link
G Lama3 laminin subunit alpha 3 increases expression ISO lysophosphatidic acid results in increased expression of LAMA3 mRNA CTD PMID:15541073 NCBI chr18:3,523,168...3,751,722
Ensembl chr18:3,523,133...3,751,353 		JBrowse link
G Lamb3 laminin subunit beta 3 increases expression ISO lysophosphatidic acid results in increased expression of LAMB3 mRNA CTD PMID:15541073 NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405 		JBrowse link
G Lamc2 laminin subunit gamma 2 increases expression ISO lysophosphatidic acid results in increased expression of LAMC2 mRNA CTD PMID:15541073 NCBI chr13:65,284,664...65,344,200
Ensembl chr13:65,284,664...65,344,200 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 increases response to substance
multiple interactions		 ISO LPAR1 protein results in increased susceptibility to lysophosphatidic acid
LPAR1 protein affects the reaction [lysophosphatidic acid results in increased stability of and affects the localization of NFE2L2 protein]; lysophosphatidic acid inhibits the reaction [CXCR1 protein binds to LPAR1 protein]; lysophosphatidic acid results in decreased expression of [CXCR1 protein binds to LPAR1 protein]		 CTD PMID:16224106 PMID:16809448 PMID:25398768 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895 		JBrowse link
G Lpar3 lysophosphatidic acid receptor 3 multiple interactions ISO Endocannabinoids inhibits the reaction [lysophosphatidic acid binds to and results in increased activity of LPAR3 protein]; lysophosphatidic acid binds to and results in increased activity of LPAR3 protein CTD PMID:30102254 NCBI chr 2:235,125,234...235,193,916
Ensembl chr 2:235,149,065...235,193,357 		JBrowse link
G Lpar5 lysophosphatidic acid receptor 5 multiple interactions ISO Endocannabinoids inhibits the reaction [lysophosphatidic acid binds to and results in increased activity of LPAR5 protein]; lysophosphatidic acid binds to and results in increased activity of LPAR5 protein CTD PMID:30102254 NCBI chr 4:157,870,493...157,883,970
Ensembl chr 4:157,881,796...157,882,950 		JBrowse link
G Lpar6 lysophosphatidic acid receptor 6 multiple interactions ISO lysophosphatidic acid binds to and results in increased activity of LPAR6 protein CTD PMID:18297070 NCBI chr15:48,416,548...48,418,357
Ensembl chr15:48,416,544...48,422,331 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation		 ISO
EXP		 Hydrogen Peroxide promotes the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]; resveratrol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]
1-Butanol inhibits the reaction [PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]; Pertussis Toxin inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]; PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]		 CTD PMID:11243883 PMID:12657697 PMID:15081308 PMID:17919812 PMID:21179406 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation		 ISO
EXP		 Hydrogen Peroxide promotes the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]; resveratrol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]
1-Butanol inhibits the reaction [PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]; Pertussis Toxin inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]; PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]		 CTD PMID:11243883 PMID:12657697 PMID:15081308 PMID:17919812 PMID:21179406 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mbp myelin basic protein multiple interactions EXP lysophosphatidic acid inhibits the reaction [ENPP2 mutant form results in decreased expression of MBP mRNA] CTD PMID:18594965 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression		 ISO gefitinib inhibits the reaction [lysophosphatidic acid results in increased expression of MMP9 mRNA]; gefitinib promotes the reaction [resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of MMP9 mRNA]]; resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of MMP9 mRNA]; resveratrol promotes the reaction [gefitinib inhibits the reaction [lysophosphatidic acid results in increased expression of MMP9 mRNA]] CTD PMID:23127547 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation EXP lysophosphatidic acid results in increased phosphorylation of MTOR protein CTD PMID:14769825 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Myl9 myosin light chain 9 increases phosphorylation
multiple interactions		 ISO lysophosphatidic acid results in increased phosphorylation of MYL9 protein
Farnesol analog inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MYL9 protein]; geranylgeraniol analog inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MYL9 protein]		 CTD PMID:24587105 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333 		JBrowse link
G Mylk myosin light chain kinase affects response to substance ISO MYLK protein affects the susceptibility to lysophosphatidic acid CTD PMID:10640419 NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO LPAR1 protein affects the reaction [lysophosphatidic acid results in increased stability of and affects the localization of NFE2L2 protein]; lysophosphatidic acid results in increased stability of and affects the localization of NFE2L2 protein
[[ONO-8430506 results in decreased activity of ENPP2 protein] which results in decreased abundance of lysophosphatidic acid] which results in decreased expression of NFE2L2		 CTD PMID:25398768 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nppa natriuretic peptide A multiple interactions
increases expression		 EXP Pertussis Toxin inhibits the reaction [lysophosphatidic acid results in increased expression of NPPA protein]; Y 27632 inhibits the reaction [lysophosphatidic acid results in increased expression of NPPA protein] CTD PMID:15081308 PMID:25449040 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha multiple interactions
increases activity		 ISO 1-Butanol inhibits the reaction [lysophosphatidic acid results in increased activity of PIP5K1A protein]; DGKA protein promotes the reaction [lysophosphatidic acid results in increased activity of PIP5K1A protein] CTD PMID:10913605 NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598 		JBrowse link
G Plau plasminogen activator, urokinase multiple interactions
increases expression		 ISO gefitinib inhibits the reaction [lysophosphatidic acid results in increased expression of PLAU mRNA]; gefitinib promotes the reaction [resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of PLAU mRNA]]; resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of PLAU mRNA]; resveratrol promotes the reaction [gefitinib inhibits the reaction [lysophosphatidic acid results in increased expression of PLAU mRNA]] CTD PMID:23127547 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Pld1 phospholipase D1 multiple interactions
increases activity		 EXP 1-Butanol inhibits the reaction [PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]]; 1-Butanol inhibits the reaction [PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]]; bisindolylmaleimide I inhibits the reaction [lysophosphatidic acid results in increased activity of PLD1 protein]; Pertussis Toxin inhibits the reaction [lysophosphatidic acid results in increased activity of PLD1 protein]; PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]; PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]; toxB protein, Clostridium difficile inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of PLD1 protein] CTD PMID:11243883 PMID:14769825 NCBI chr 2:110,849,205...111,047,692
Ensembl chr 2:110,893,608...111,047,692 		JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A increases phosphorylation
multiple interactions		 EXP lysophosphatidic acid results in increased phosphorylation of PPP1R12A protein
Y 27632 inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of PPP1R12A protein]		 CTD PMID:25449040 NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425 		JBrowse link
G Ptk2 protein tyrosine kinase 2 increases phosphorylation
multiple interactions		 ISO
EXP		 lysophosphatidic acid results in increased phosphorylation of PTK2 protein
[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein; KNG1 protein inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein]
[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein; Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein]]; oxotremorine M inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein]		 CTD PMID:10537051 PMID:11792571 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta increases phosphorylation ISO lysophosphatidic acid results in increased phosphorylation of PTK2B protein CTD PMID:11792571 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Rhoa ras homolog family member A increases activity
multiple interactions		 EXP
ISO		 lysophosphatidic acid results in increased activity of RHOA protein
Farnesol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOA protein]; geranylgeraniol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOA protein]		 CTD PMID:15081308 PMID:24587105 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Rhoc ras homolog family member C multiple interactions
increases activity		 ISO Farnesol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOC protein]; geranylgeraniol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOC protein] CTD PMID:24587105 NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 increases phosphorylation
multiple interactions		 ISO
EXP		 lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein
resveratrol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein]
1-Butanol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein]; exoenzyme C3, Clostridium botulinum inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein]		 CTD PMID:14769825 PMID:17919812 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Tfrc transferrin receptor multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; WP1066 inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein] CTD PMID:21915944 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions
increases expression		 ISO 3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of TIMP1 protein] CTD PMID:25822713 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO TNF protein inhibits the reaction [lysophosphatidic acid results in decreased expression of ENPP2 protein] CTD PMID:25896349 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression
multiple interactions		 ISO [lysophosphatidic acid results in increased expression of HIF1A protein] which results in increased expression of VEGFA mRNA; [lysophosphatidic acid results in increased expression of HIF1A protein] which results in increased expression of VEGFA protein
resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of VEGFA protein]		 CTD PMID:17919812 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
1-octadecanoyl-2-[(9Z)-octadecenoyl]-sn-glycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipc lipase C, hepatic type multiple interactions
decreases abundance		 ISO [LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol
LIPC gene mutant form results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol		 CTD PMID:24777581 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464 		JBrowse link
G Lipg lipase G, endothelial type decreases abundance
multiple interactions		 ISO LIPG gene mutant form results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol		 CTD PMID:24777581 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260 		JBrowse link
1-Oleoyl-2-acetyl-sn-glycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO 1-oleoyl-2-acetylglycerol inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; 1-oleoyl-2-acetylglycerol results in increased phosphorylation of and results in decreased expression of ABCA1 protein CTD PMID:16118212 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO 1-oleoyl-2-acetylglycerol inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]] CTD PMID:16118212 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 multiple interactions ISO 1-oleoyl-2-acetylglycerol promotes the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium] CTD PMID:18316702 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Fgg fibrinogen gamma chain increases expression ISO 1-oleoyl-2-acetylglycerol results in increased expression of FGG mRNA CTD PMID:2440878 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Ins2 insulin 2 affects response to substance ISO INS protein affects the susceptibility to 1-oleoyl-2-acetylglycerol CTD PMID:22031853 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Pthlh parathyroid hormone-like hormone increases secretion EXP 1-oleoyl-2-acetylglycerol results in increased secretion of PTHLH protein CTD PMID:7946399 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity
multiple interactions		 ISO 1-oleoyl-2-acetylglycerol results in increased activity of TRPA1 protein
Ruthenium Red inhibits the reaction [1-oleoyl-2-acetylglycerol results in increased activity of TRPA1 protein]		 CTD PMID:15046718 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570 		JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 increases activity
multiple interactions		 ISO 1-oleoyl-2-acetylglycerol results in increased activity of TRPC3 protein
ethyl-1-(4-(2*3*3-trichloroacrylamide)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate inhibits the reaction [1-oleoyl-2-acetylglycerol results in increased activity of TRPC3 protein]
1-oleoyl-2-acetylglycerol affects the reaction [TRPC3 protein affects the transport of Calcium]; 1-oleoyl-2-acetylglycerol promotes the reaction [TRPC3 protein results in increased transport of Barium]; 1-oleoyl-2-acetylglycerol promotes the reaction [TRPC3 protein results in increased transport of Calcium]		 CTD PMID:11042129 PMID:12700192 PMID:16522635 PMID:17351372 PMID:18316702 More... NCBI chr 2:119,481,313...119,619,333
Ensembl chr 2:119,481,400...119,558,855 		JBrowse link
G Trpc4 transient receptor potential cation channel, subfamily C, member 4 multiple interactions ISO TRPC4 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Strontium] CTD PMID:11830588 NCBI chr 2:138,307,676...138,476,856
Ensembl chr 2:138,308,084...138,476,768 		JBrowse link
G Trpc5 transient receptor potential cation channel, subfamily C, member 5 multiple interactions ISO 1-oleoyl-2-acetylglycerol affects the reaction [TRPC5 protein affects the transport of Calcium] CTD PMID:17351372 NCBI chr  X:107,946,163...108,230,978
Ensembl chr  X:107,939,131...108,230,991 		JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 increases activity
multiple interactions
affects response to substance		 ISO
EXP		 1-oleoyl-2-acetylglycerol results in increased activity of TRPC6 protein
4-((3,4-(methylenedioxy)benzyl)amino)-6-methoxyquinazoline analog inhibits the reaction [1-oleoyl-2-acetylglycerol results in increased activity of TRPC6 protein]; 8-bromocyclic GMP inhibits the reaction [1-oleoyl-2-acetylglycerol results in increased activity of TRPC6 protein]; KT 5823 inhibits the reaction [4-((3,4-(methylenedioxy)benzyl)amino)-6-methoxyquinazoline analog inhibits the reaction [1-oleoyl-2-acetylglycerol results in increased activity of TRPC6 protein]]; S-Nitroso-N-Acetylpenicillamine inhibits the reaction [1-oleoyl-2-acetylglycerol results in increased activity of TRPC6 protein]
1-oleoyl-2-acetylglycerol results in increased activity of TRPC6 protein; 1-oleoyl-2-acetylglycerol results in increased activity of TRPC6 protein mutant form
TRPC6 protein affects the susceptibility to 1-oleoyl-2-acetylglycerol		 CTD PMID:18316702 PMID:20177073 PMID:22031853 NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092 		JBrowse link
G Trpm6 transient receptor potential cation channel, subfamily M, member 6 multiple interactions ISO Gadolinium inhibits the reaction [TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Calcium]]; Lanthanum inhibits the reaction [TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Calcium]]; TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Barium]; TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Calcium]; TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Strontium] CTD PMID:11988098 NCBI chr 1:216,136,407...216,320,523
Ensembl chr 1:216,170,038...216,320,520 		JBrowse link
1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipg lipase G, endothelial type increases hydrolysis ISO LIPG protein results in increased hydrolysis of 1-O-hexadecyl-2-arachidonyl-sn-glycero-3-phosphocholine CTD PMID:15953354 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260 		JBrowse link
1-palmitoyl-2-oleoyl-sn-glycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipc lipase C, hepatic type decreases abundance ISO LIPC gene mutant form results in decreased abundance of 1-palmitoyl-2-oleoyl-sn-glycerol CTD PMID:24777581 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464 		JBrowse link
G Lipg lipase G, endothelial type decreases abundance ISO LIPG gene mutant form results in decreased abundance of 1-palmitoyl-2-oleoyl-sn-glycerol CTD PMID:24777581 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260 		JBrowse link
1-stearoyl-2-arachidonoyl-sn-glycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO 1-stearoyl-2-arachidonoylglycerol inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] CTD PMID:27936102 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Dagla diacylglycerol lipase, alpha increases metabolic processing ISO DAGLA protein results in increased metabolism of 1-stearoyl-2-arachidonoylglycerol CTD PMID:18657971 NCBI chr 1:206,890,635...206,947,332
Ensembl chr 1:206,890,638...206,947,232 		JBrowse link
G Daglb diacylglycerol lipase, beta increases metabolic processing ISO DAGLB protein results in increased metabolism of 1-stearoyl-2-arachidonoylglycerol CTD PMID:18657971 NCBI chr12:11,059,732...11,102,170
Ensembl chr12:11,059,732...11,102,154 		JBrowse link
G Dgke diacylglycerol kinase epsilon increases phosphorylation ISO DGKE protein results in increased phosphorylation of 1-stearoyl-2-arachidonoylglycerol CTD PMID:17455907 NCBI chr10:73,852,679...73,877,334
Ensembl chr10:73,855,583...73,877,100 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO 1-stearoyl-2-arachidonoylglycerol results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO 1-stearoyl-2-arachidonoylglycerol inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] CTD PMID:27936102 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Trpm6 transient receptor potential cation channel, subfamily M, member 6 multiple interactions ISO TRPM6 protein affects the reaction [1-stearoyl-2-arachidonoylglycerol results in increased transport of Barium]; TRPM6 protein affects the reaction [1-stearoyl-2-arachidonoylglycerol results in increased transport of Calcium] CTD PMID:11988098 NCBI chr 1:216,136,407...216,320,523
Ensembl chr 1:216,170,038...216,320,520 		JBrowse link
1-stearoyl-2-linoleoyl-sn-glycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipc lipase C, hepatic type decreases abundance ISO LIPC gene mutant form results in decreased abundance of 1-stearoyl-2-linoleoyl-sn-glycerol CTD PMID:24777581 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464 		JBrowse link
G Lipg lipase G, endothelial type decreases abundance ISO LIPG gene mutant form results in decreased abundance of 1-stearoyl-2-linoleoyl-sn-glycerol CTD PMID:24777581 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260 		JBrowse link
1-stearoyl-sn-glycero-3-phosphocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipc lipase C, hepatic type multiple interactions ISO [LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of stearoyl alpha-lysolecithin CTD PMID:24777581 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464 		JBrowse link
G Lipg lipase G, endothelial type multiple interactions ISO [LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of stearoyl alpha-lysolecithin CTD PMID:24777581 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260 		JBrowse link
2-acetyl-1-alkyl-sn-glycero-3-phosphocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a increases expression ISO Platelet Activating Factor results in increased expression of AGTR1 mRNA CTD PMID:16386258 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type increases expression ISO Platelet Activating Factor results in increased expression of ALOX12 mRNA CTD PMID:16386258 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions
increases expression		 ISO [sodium arsenite co-treated with Platelet Activating Factor co-treated with Arachidonic Acid] results in increased phosphorylation of and results in increased activity of ALOX5 protein; [zileuton results in decreased activity of ALOX5 protein] inhibits the reaction [Calcimycin results in increased abundance of Platelet Activating Factor]
Platelet Activating Factor results in increased expression of ALOX5 mRNA		 CTD PMID:8387780 PMID:10779545 PMID:16386258 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases secretion		 ISO Foropafant inhibits the reaction [Platelet Activating Factor results in increased secretion of CCL2 protein] CTD PMID:15149885 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression ISO Platelet Activating Factor results in increased expression of CCR2 mRNA CTD PMID:16386258 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Crp C-reactive protein increases expression ISO Platelet Activating Factor results in increased expression of CRP mRNA CTD PMID:16386258 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 increases expression ISO Platelet Activating Factor results in increased expression of CX3CR1 mRNA CTD PMID:16386258 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014 		JBrowse link
G Edn1 endothelin 1 multiple interactions
increases abundance		 EXP Carbon Tetrachloride promotes the reaction [EDN1 protein results in increased abundance of Platelet Activating Factor]; EDNRB protein affects the reaction [Carbon Tetrachloride promotes the reaction [EDN1 protein results in increased abundance of Platelet Activating Factor]]; EDNRB protein affects the reaction [EDN1 protein results in increased abundance of Platelet Activating Factor] CTD PMID:18205269 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednrb endothelin receptor type B multiple interactions EXP EDNRB protein affects the reaction [Carbon Tetrachloride promotes the reaction [EDN1 protein results in increased abundance of Platelet Activating Factor]]; EDNRB protein affects the reaction [EDN1 protein results in increased abundance of Platelet Activating Factor] CTD PMID:18205269 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Egr1 early growth response 1 increases expression ISO Platelet Activating Factor results in increased expression of EGR1 mRNA CTD PMID:16386258 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Gusb glucuronidase, beta multiple interactions EXP [Platelet Activating Factor co-treated with Cytochalasin B] results in increased secretion of GUSB protein; IMMLG5521 inhibits the reaction [[Platelet Activating Factor co-treated with Cytochalasin B] results in increased secretion of GUSB protein] CTD PMID:23850278 NCBI chr12:26,701,191...26,714,718
Ensembl chr12:26,697,951...26,726,905 		JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Platelet Activating Factor results in increased expression of IL1A mRNA CTD PMID:16386258 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta increases expression
increases secretion
multiple interactions		 ISO Platelet Activating Factor results in increased expression of IL1B mRNA
Platelet Activating Factor results in increased secretion of IL1B protein
[Platelet Activating Factor co-treated with MIR149 mRNA] affects the secretion of IL1B protein; PVT1 mRNA affects the reaction [Platelet Activating Factor results in increased secretion of IL1B protein]		 CTD PMID:16386258 PMID:32830409 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion		 ISO [Platelet Activating Factor co-treated with MIR149 mRNA] affects the secretion of IL6 protein; PVT1 mRNA affects the reaction [Platelet Activating Factor results in increased secretion of IL6 protein] CTD PMID:32830409 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Itgam integrin subunit alpha M multiple interactions
increases expression		 ISO Foropafant inhibits the reaction [Platelet Activating Factor results in increased expression of ITGAM protein]; Isoproterenol promotes the reaction [Theophylline inhibits the reaction [Platelet Activating Factor results in increased expression of ITGAM protein]]; Theophylline inhibits the reaction [Platelet Activating Factor results in increased expression of ITGAM protein] CTD PMID:9762784 PMID:11116075 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Ltb4r leukotriene B4 receptor affects response to substance ISO LTB4R1 protein affects the susceptibility to Platelet Activating Factor CTD PMID:10934231 NCBI chr15:29,263,126...29,265,716 JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression ISO Platelet Activating Factor results in increased expression of MMP13 mRNA CTD PMID:16386258 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor increases expression
multiple interactions		 ISO Platelet Activating Factor results in increased expression of MYD88 protein
PVT1 mRNA affects the reaction [Platelet Activating Factor results in increased expression of MYD88 protein]		 CTD PMID:32830409 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 multiple interactions ISO NCEH1 protein inhibits the reaction [[Chlorpyrifos metabolite co-treated with Cytidine Diphosphate Choline] results in increased abundance of Platelet Activating Factor] CTD PMID:18164358 NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases degradation		 ISO Acetylcysteine inhibits the reaction [Platelet Activating Factor results in increased degradation of NFKBIA protein]; BN 50739 inhibits the reaction [Platelet Activating Factor results in increased degradation of NFKBIA protein]; Genistein inhibits the reaction [Platelet Activating Factor results in increased degradation of NFKBIA protein]; herbimycin inhibits the reaction [Platelet Activating Factor results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Platelet Activating Factor results in increased degradation of NFKBIA protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Platelet Activating Factor results in increased degradation of NFKBIA protein]; Vitamin E inhibits the reaction [Platelet Activating Factor results in increased degradation of NFKBIA protein] CTD PMID:10921504 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 increases expression ISO Platelet Activating Factor results in increased expression of OLR1 mRNA CTD PMID:16386258 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523 		JBrowse link
G Pla2g7 phospholipase A2 group VII multiple interactions
increases expression		 ISO [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Platelet Activating Factor] results in increased expression of PLA2G7 mRNA; bepafant inhibits the reaction [Platelet Activating Factor results in increased expression of PLA2G7 mRNA] CTD PMID:21432021 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO Platelet Activating Factor results in decreased expression of PPARA mRNA CTD PMID:16386258 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ptafr platelet-activating factor receptor multiple interactions
increases expression
increases phosphorylation
affects binding		 ISO
EXP		 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine inhibits the reaction [Platelet Activating Factor binds to PTAFR protein]; BN 50730 inhibits the reaction [Platelet Activating Factor binds to PTAFR protein]; BN 50739 inhibits the reaction [Platelet Activating Factor binds to PTAFR protein]; CMI 392 inhibits the reaction [Platelet Activating Factor binds to PTAFR protein]; MK 287 inhibits the reaction [Platelet Activating Factor binds to PTAFR protein]; zileuton inhibits the reaction [Platelet Activating Factor binds to PTAFR protein]
Platelet Activating Factor results in increased expression of PTAFR mRNA
Platelet Activating Factor results in increased phosphorylation of PTAFR protein
bepafant inhibits the reaction [Platelet Activating Factor results in increased expression of PTAFR mRNA]; Carbon Tetrachloride promotes the reaction [Platelet Activating Factor binds to PTAFR protein]; RGS4 protein inhibits the reaction [Platelet Activating Factor results in increased phosphorylation of PTAFR protein]; TNF protein affects the reaction [Platelet Activating Factor results in increased expression of PTAFR mRNA]		 CTD PMID:9065783 PMID:10447766 PMID:11297424 PMID:11529688 PMID:16386258 More... NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 increases expression ISO Platelet Activating Factor results in increased expression of PTGS1 mRNA CTD PMID:16386258 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Platelet Activating Factor results in increased expression of PTGS2 mRNA CTD PMID:16386258 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pvt1 Pvt1 oncogene increases expression
multiple interactions		 ISO Platelet Activating Factor results in increased expression of PVT1 mRNA
[Platelet Activating Factor co-treated with PVT1 mRNA] affects the expression of MIR149 mRNA; PVT1 mRNA affects the reaction [Platelet Activating Factor results in increased expression of MYD88 protein]; PVT1 mRNA affects the reaction [Platelet Activating Factor results in increased secretion of IL1B protein]; PVT1 mRNA affects the reaction [Platelet Activating Factor results in increased secretion of IL6 protein]; PVT1 mRNA affects the reaction [Platelet Activating Factor results in increased secretion of TNF protein]		 CTD PMID:32830409 NCBI chr 7:93,656,249...93,879,938 JBrowse link
G Rgs4 regulator of G-protein signaling 4 multiple interactions EXP RGS4 protein inhibits the reaction [Platelet Activating Factor results in increased phosphorylation of PTAFR protein] CTD PMID:11297424 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Sele selectin E increases expression ISO Platelet Activating Factor results in increased expression of SELE mRNA CTD PMID:16386258 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741 		JBrowse link
G Sell selectin L multiple interactions
increases secretion		 ISO Isoproterenol promotes the reaction [Theophylline inhibits the reaction [Platelet Activating Factor results in increased secretion of SELL protein]]; Theophylline inhibits the reaction [Platelet Activating Factor results in increased secretion of SELL protein] CTD PMID:9762784 NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456 		JBrowse link
G Selp selectin P multiple interactions
increases expression		 ISO Foropafant inhibits the reaction [Platelet Activating Factor results in increased expression of SELP protein] CTD PMID:11116075 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845 		JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 increases expression ISO Platelet Activating Factor results in increased expression of TIMP4 mRNA CTD PMID:16386258 NCBI chr 4:148,306,021...148,312,558
Ensembl chr 4:148,304,490...148,312,558 		JBrowse link
G Tnf tumor necrosis factor increases secretion
multiple interactions
increases expression		 ISO
EXP		 Platelet Activating Factor results in increased secretion of TNF protein
[Platelet Activating Factor co-treated with MIR149 mRNA] affects the secretion of TNF protein; PVT1 mRNA affects the reaction [Platelet Activating Factor results in increased secretion of TNF protein]
TNF protein affects the reaction [Platelet Activating Factor results in increased expression of PTAFR mRNA]
Platelet Activating Factor results in increased expression of TNF mRNA
Acetylcysteine inhibits the reaction [Platelet Activating Factor results in increased expression of TNF mRNA]; BN 50739 inhibits the reaction [Platelet Activating Factor results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Platelet Activating Factor results in increased expression of TNF mRNA]; Vitamin E inhibits the reaction [Platelet Activating Factor results in increased expression of TNF mRNA]		 CTD PMID:9065783 PMID:10921504 PMID:16386258 PMID:32830409 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
2-arachidonoylglycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd12 abhydrolase domain containing 12, lysophospholipase increases hydrolysis ISO ABHD12 protein results in increased hydrolysis of glyceryl 2-arachidonate CTD PMID:18096503 NCBI chr 3:139,659,315...139,719,529
Ensembl chr 3:139,659,317...139,719,564 		JBrowse link
G Abhd6 abhydrolase domain containing 6, acylglycerol lipase increases hydrolysis ISO ABHD6 protein results in increased hydrolysis of glyceryl 2-arachidonate CTD PMID:18096503 NCBI chr15:16,859,740...16,907,094
Ensembl chr15:16,859,738...16,906,985 		JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression
multiple interactions		 EXP glyceryl 2-arachidonate results in increased expression of ACTA2 mRNA
Acetaldehyde promotes the reaction [glyceryl 2-arachidonate results in increased expression of ACTA2 mRNA]		 CTD PMID:21863215 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Apoe apolipoprotein E multiple interactions ISO [[APOE protein affects the susceptibility to [Cholesterol, Dietary co-treated with Dietary Fats]] which affects the susceptibility to JZL 184] which affects the abundance of glyceryl 2-arachidonate CTD PMID:29813086 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions ISO glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]; glyceryl 2-arachidonate promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]; GRK2 protein promotes the reaction [glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]] CTD PMID:31024316 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO [GRK2 protein co-treated with glyceryl 2-arachidonate] affects the reaction [CNR1 protein affects the localization of ARRB2 protein]; [GRK2 protein co-treated with glyceryl 2-arachidonate] promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; glyceryl 2-arachidonate promotes the reaction [CNR1 protein affects the localization of ARRB2 protein]; glyceryl 2-arachidonate promotes the reaction [CNR2 protein affects the localization of ARRB2 protein] CTD PMID:31024316 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Atf4 activating transcription factor 4 increases expression
multiple interactions		 ISO glyceryl 2-arachidonate results in increased expression of ATF4 mRNA
iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased expression of ATF4 mRNA]		 CTD PMID:32357311 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO glyceryl 2-arachidonate results in increased expression of BTG2 mRNA CTD PMID:28095641 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO glyceryl 2-arachidonate results in increased expression of CCL2 protein CTD PMID:15115777 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 increases expression ISO glyceryl 2-arachidonate results in increased expression of CCR1 mRNA CTD PMID:29813086 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Cd36 CD36 molecule increases expression ISO glyceryl 2-arachidonate results in increased expression of CD36 mRNA CTD PMID:29813086 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Ces1d carboxylesterase 1D increases hydrolysis
multiple interactions		 ISO CES1 protein results in increased hydrolysis of glyceryl 2-arachidonate
[CES1 protein results in increased hydrolysis of glyceryl 2-arachidonate] which results in increased chemical synthesis of Arachidonic Acid		 CTD PMID:21049984 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Ces2h carboxylesterase 2H increases hydrolysis
multiple interactions		 ISO CES2 protein results in increased hydrolysis of glyceryl 2-arachidonate
[CES2 protein results in increased hydrolysis of glyceryl 2-arachidonate] which results in increased chemical synthesis of Arachidonic Acid		 CTD PMID:21049984 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830 		JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
increases expression		 ISO
EXP		 CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7B1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP8B1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; CNR1 protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]
glyceryl 2-arachidonate results in increased expression of CNR1 mRNA
[GRK2 protein co-treated with glyceryl 2-arachidonate] affects the reaction [CNR1 protein affects the localization of ARRB2 protein]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP8B1 mRNA]; glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]; glyceryl 2-arachidonate promotes the reaction [CNR1 protein affects the localization of ARRB2 protein]; GRK2 protein promotes the reaction [glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]]
Acetaldehyde promotes the reaction [glyceryl 2-arachidonate results in increased expression of CNR1 mRNA]; Nitroglycerin affects the reaction [glyceryl 2-arachidonate affects the activity of CNR1 protein]		 CTD PMID:12657697 PMID:15899896 PMID:16775503 PMID:21863215 PMID:23894352 More... NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions
affects response to substance		 ISO [GRK2 protein co-treated with glyceryl 2-arachidonate] promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; [SR 144528 binds to and results in increased activity of CNR2 protein] inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CXCL8 protein]; CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased expression of CXCL8 protein]; CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]; glyceryl 2-arachidonate binds to and results in increased activity of CNR2 protein; glyceryl 2-arachidonate promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]; glyceryl 2-arachidonate promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; Pertussis Toxin inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]]; SR 144528 inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]]
CNR2 gene SNP affects the susceptibility to glyceryl 2-arachidonate		 CTD PMID:10617657 PMID:15115777 PMID:20124950 PMID:27194477 PMID:30102254 More... NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548 		JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 multiple interactions
increases expression		 ISO glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]; glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CREB3L3 mRNA] CTD PMID:23894352 NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048 		JBrowse link
G Crh corticotropin releasing hormone increases abundance ISO CRH protein results in increased abundance of glyceryl 2-arachidonate CTD PMID:26821211 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions
increases expression		 ISO CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA]; glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA] CTD PMID:23894352 PMID:28095641 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions
increases expression		 ISO CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA]; glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA] CTD PMID:23894352 PMID:28095641 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 increases expression
multiple interactions		 ISO glyceryl 2-arachidonate results in increased expression of CYP7B1 mRNA
CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7B1 mRNA]		 CTD PMID:23894352 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 increases expression
multiple interactions		 ISO glyceryl 2-arachidonate results in increased expression of CYP8B1 mRNA
CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP8B1 mRNA]		 CTD PMID:23894352 PMID:28095641 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166 		JBrowse link
G Dagla diacylglycerol lipase, alpha multiple interactions ISO 1-((fluoro(methyl)phosphoryl)oxy)-3-isopropoxypropan-2-yl oleate inhibits the reaction [DAGLA protein modified form results in increased chemical synthesis of glyceryl 2-arachidonate] CTD PMID:27071101 NCBI chr 1:206,890,635...206,947,332
Ensembl chr 1:206,890,638...206,947,232 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions		 ISO glyceryl 2-arachidonate results in increased expression of DDIT3 mRNA; glyceryl 2-arachidonate results in increased expression of DDIT3 protein
iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased expression of DDIT3 mRNA]; iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased expression of DDIT3 protein]		 CTD PMID:29441458 PMID:32357311 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions
increases phosphorylation		 ISO GSK2656157 inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of EIF2S1 protein]; iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of EIF2S1 protein] CTD PMID:32357311 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Esrrg estrogen-related receptor gamma increases abundance ISO ESRRG protein results in increased abundance of glyceryl 2-arachidonate CTD PMID:31912162 NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397 		JBrowse link
G Fabp1 fatty acid binding protein 1 affects abundance
multiple interactions		 ISO FABP1 protein affects the abundance of glyceryl 2-arachidonate
FABP1 protein affects the reaction [Dronabinol results in increased abundance of glyceryl 2-arachidonate]; FABP1 protein affects the reaction [glyceryl 2-arachidonate results in increased abundance of anandamide]		 CTD PMID:29414765 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 multiple interactions ISO [FMR1 gene mutant form results in increased activity of MGLL] which results in increased degradation of glyceryl 2-arachidonate CTD PMID:20393458 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions EXP FYN gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; FYN gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:12657697 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 multiple interactions ISO [GRK2 protein co-treated with glyceryl 2-arachidonate] affects the reaction [CNR1 protein affects the localization of ARRB2 protein]; [GRK2 protein co-treated with glyceryl 2-arachidonate] promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; GRK2 protein promotes the reaction [glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]] CTD PMID:31024316 NCBI chr 1:201,581,480...201,601,580
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Hcrt hypocretin neuropeptide precursor increases chemical synthesis
multiple interactions		 ISO HCRT protein modified form results in increased chemical synthesis of glyceryl 2-arachidonate
1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea inhibits the reaction [HCRT protein modified form results in increased chemical synthesis of glyceryl 2-arachidonate]		 CTD PMID:27071101 NCBI chr10:85,689,992...85,691,206
Ensembl chr10:85,689,465...85,691,210 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO glyceryl 2-arachidonate results in increased expression of HSPA5 mRNA CTD PMID:32357311 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO glyceryl 2-arachidonate results in increased expression of ICAM1 mRNA CTD PMID:29813086 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Il1b interleukin 1 beta decreases expression
multiple interactions		 ISO glyceryl 2-arachidonate results in decreased expression of IL1B mRNA
glyceryl 2-arachidonate inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL1B protein]]		 CTD PMID:16364651 PMID:30611738 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO glyceryl 2-arachidonate metabolite inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]; T 0070907 inhibits the reaction [glyceryl 2-arachidonate metabolite inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]] CTD PMID:21511917 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions		 ISO glyceryl 2-arachidonate results in decreased expression of IL6 mRNA
glyceryl 2-arachidonate inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]]		 CTD PMID:16364651 PMID:30611738 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ins2 insulin 2 multiple interactions ISO INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CREB3L3 mRNA]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA] CTD PMID:23894352 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Lep leptin multiple interactions ISO [Dietary Fats co-treated with LEP protein] results in increased chemical synthesis of glyceryl 2-arachidonate CTD PMID:27071101 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K1 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K1 protein; U 0126 inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K1 protein] CTD PMID:12657697 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K2 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K2 protein; U 0126 inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K2 protein] CTD PMID:12657697 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation		 ISO
EXP		 CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein
glyceryl 2-arachidonate results in decreased phosphorylation of MAPK1 protein
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; FYN gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in decreased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]		 CTD PMID:12657697 PMID:31917333 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation		 ISO
EXP		 CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein
glyceryl 2-arachidonate results in decreased phosphorylation of MAPK3 protein
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; FYN gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in decreased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]		 CTD PMID:12657697 PMID:31917333 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mgll monoglyceride lipase multiple interactions
affects abundance
increases degradation
increases abundance
increases hydrolysis		 EXP
ISO		 [Chlorpyrifos results in decreased activity of MGLL protein] which results in increased abundance of glyceryl 2-arachidonate; JZL 184 inhibits the reaction [MGLL protein results in increased hydrolysis of glyceryl 2-arachidonate]
MGLL protein affects the abundance of glyceryl 2-arachidonate
MGLL protein results in increased degradation of glyceryl 2-arachidonate
[FMR1 gene mutant form results in increased activity of MGLL] which results in increased degradation of glyceryl 2-arachidonate; [JZL 184 results in decreased activity of MGLL protein] which results in increased abundance of glyceryl 2-arachidonate; [MJN110 results in decreased activity of MGLL protein] which results in decreased hydrolysis of and results in increased abundance of glyceryl 2-arachidonate
MGLL gene mutant form results in increased abundance of glyceryl 2-arachidonate		 CTD PMID:18096503 PMID:20393458 PMID:21507991 PMID:23761300 PMID:25030704 More... NCBI chr 4:121,192,187...121,294,187
Ensembl chr 4:121,192,195...121,294,179 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO glyceryl 2-arachidonate inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased activity of MPO protein]] CTD PMID:30611738 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage		 ISO GSK2656157 inhibits the reaction [glyceryl 2-arachidonate results in increased cleavage of PARP1 protein] CTD PMID:29441458 PMID:32357311 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects localization
multiple interactions		 EXP glyceryl 2-arachidonate affects the localization of PPARA protein
[palmidrol co-treated with glyceryl 2-arachidonate] affects the localization of PPARA protein; [palmidrol co-treated with glyceryl 2-arachidonate] affects the reaction [lipopolysaccharide, E. coli O26-B6 affects the localization of PPARA protein]; glyceryl 2-arachidonate affects the reaction [lipopolysaccharide, E. coli O26-B6 affects the localization of PPARA protein]		 CTD PMID:31787870 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding
multiple interactions
increases expression		 ISO glyceryl 2-arachidonate metabolite binds to PPARG protein
glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in decreased expression of PPARG protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]
T 0070907 inhibits the reaction [glyceryl 2-arachidonate metabolite results in increased expression of PPARG mRNA]		 CTD PMID:21511917 PMID:26209559 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP [Indomethacin results in decreased expression of PTGS1] which results in increased activity of glyceryl 2-arachidonate CTD PMID:17245358 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases metabolic processing
multiple interactions		 ISO PTGS2 protein results in increased metabolism of glyceryl 2-arachidonate
2-chloro-5-nitrobenzanilide inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; rimonabant inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]
glyceryl 2-arachidonate inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased expression of PTGS2 mRNA]; Ibuprofen inhibits the reaction [PTGS2 protein results in increased metabolism of glyceryl 2-arachidonate]		 CTD PMID:18297109 PMID:21511917 PMID:26209559 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]; glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] CTD PMID:26209559 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions		 ISO
EXP		 glyceryl 2-arachidonate results in decreased expression of TNF mRNA
glyceryl 2-arachidonate inhibits the reaction [[Serotonin co-treated with Dextran Sulfate] results in increased expression of TNF protein]; glyceryl 2-arachidonate inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of TNF protein]
glyceryl 2-arachidonate inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF protein]		 CTD PMID:12509806 PMID:16364651 PMID:30611738 PMID:30769029 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
affects response to substance		 EXP
ISO		 glyceryl 2-arachidonate binds to and results in increased activity of TRPV1 protein
TRPV1 protein affects the susceptibility to glyceryl 2-arachidonate		 CTD PMID:18550765 PMID:21949157 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
G Yy1 YY1 transcription factor increases expression ISO glyceryl 2-arachidonate results in increased expression of YY1 mRNA CTD PMID:28095641 NCBI chr 6:127,706,739...127,731,907
Ensembl chr 6:127,707,596...127,732,747 		JBrowse link
2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnf tumor necrosis factor increases expression EXP platelet-activating factor increases expression of Tnf protein in portal stenosis rat plasma RGD PMID:10452877 RGD:38508900 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
2-oleoylglycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fabp1 fatty acid binding protein 1 affects abundance ISO FABP1 protein affects the abundance of 2-oleoylglycerol CTD PMID:29414765 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788 		JBrowse link
G Mgll monoglyceride lipase increases degradation
multiple interactions		 EXP MGLL protein results in increased degradation of 2-oleoylglycerol
Nitroglycerin promotes the reaction [MGLL protein results in increased degradation of 2-oleoylglycerol]		 CTD PMID:19515121 NCBI chr 4:121,192,187...121,294,187
Ensembl chr 4:121,192,195...121,294,179 		JBrowse link
castor oil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 increases expression
multiple interactions		 EXP Castor Oil results in increased expression of PAFAH1B1 protein
isosorbide-5-mononitrate inhibits the reaction [Castor Oil results in increased expression of PAFAH1B1 protein]		 CTD PMID:1354728 PMID:2743081 PMID:8738301 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808 		JBrowse link
dioleoyl phosphatidic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plek pleckstrin multiple interactions ISO dioleoylphosphatidic acid analog promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased phosphorylation of PLEK protein] CTD PMID:8928743 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [1,2-oleoylphosphatidylcholine co-treated with dioleoylphosphatidic acid] binds to SOD1 protein; [1,2-oleoylphosphatidylcholine co-treated with dioleoylphosphatidic acid] binds to SOD1 protein mutant form; [1,2-oleoylphosphatidylcholine co-treated with dioleoylphosphatidic acid] promotes the reaction [SOD1 protein binds to SOD1 protein]; [1,2-oleoylphosphatidylcholine co-treated with dioleoylphosphatidic acid] promotes the reaction [SOD1 protein mutant form binds to SOD1 protein mutant form] CTD PMID:29649360 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
dipalmitoyl phosphatidylglycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pon1 paraoxonase 1 multiple interactions ISO 1,2-dipalmitoylphosphatidylglycerol inhibits the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]] CTD PMID:15104111 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
edelfosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO edelfosine inhibits the reaction [Nicotine results in increased phosphorylation of BCL2 protein]; edelfosine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2 protein]; edelfosine promotes the reaction [Cytarabine results in decreased expression of BCL2 protein] CTD PMID:9295281 PMID:12421819 NCBI chr13:22,689,783...22,853,920 JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions ISO edelfosine inhibits the reaction [F2RL1 protein promotes the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]]; edelfosine inhibits the reaction [F2RL1 protein promotes the reaction [cinnamaldehyde results in increased activity of TRPA1 protein]] CTD PMID:17571167 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Lep leptin multiple interactions ISO edelfosine inhibits the reaction [LEP protein results in increased transport of Calcium] CTD PMID:20107083 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Plcb2 phospholipase C, beta 2 multiple interactions ISO edelfosine inhibits the reaction [Cytarabine affects the localization of PLCB2 protein]; edelfosine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PLCB2 protein] CTD PMID:9295281 NCBI chr 3:105,683,676...105,704,384
Ensembl chr 3:105,684,815...105,704,302 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO edelfosine results in increased expression of PTGS2 protein CTD PMID:12485854 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 multiple interactions ISO edelfosine inhibits the reaction [F2RL1 protein promotes the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]]; edelfosine inhibits the reaction [F2RL1 protein promotes the reaction [cinnamaldehyde results in increased activity of TRPA1 protein]] CTD PMID:17571167 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570 		JBrowse link
glycerylphosphorylcholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdpd5 glycerophosphodiester phosphodiesterase domain containing 5 affects abundance ISO GDPD5 protein affects the abundance of Glycerylphosphorylcholine CTD PMID:33617914 NCBI chr 1:153,679,718...153,761,452
Ensembl chr 1:153,679,718...153,761,446 		JBrowse link
lipoarabinomannan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf2 colony stimulating factor 2 multiple interactions ISO CSF2 protein promotes the reaction [lipoarabinomannan results in increased secretion of CXCL8 protein] CTD PMID:12176910 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 decreases expression ISO lipoarabinomannan results in decreased expression of CXCR2 protein CTD PMID:10950785 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO lipoarabinomannan inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:16263713 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 multiple interactions ISO lipoarabinomannan inhibits the reaction [IRAK1 protein binds to TRAF6 protein] CTD PMID:16263713 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 increases expression
increases expression 		ISO lipoarabinomannan results in increased expression of IRAK3 protein
Lipoarabinomannan increases expression of Irak3 mRNA and protein in macrophages		 CTD
RGD		 PMID:16263713 PMID:16263713 RGD:36049804 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Mmp9 matrix metallopeptidase 9 increases activity ISO lipoarabinomannan results in increased activity of MMP9 protein CTD PMID:11839551 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO lipoarabinomannan results in decreased localization of and results in decreased activity of NFKB1 protein CTD PMID:16263713 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha decreases phosphorylation ISO lipoarabinomannan results in decreased phosphorylation of NFKBIA protein CTD PMID:16263713 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions ISO lipoarabinomannan results in decreased localization of and results in decreased activity of REL protein CTD PMID:16263713 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892 		JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions ISO lipoarabinomannan inhibits the reaction [IRAK1 protein binds to TRAF6 protein] CTD PMID:16263713 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
lipophosphoglycan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule multiple interactions ISO CD14 protein promotes the reaction [lipopeptidophosphoglycan results in increased activity of TLR2 protein]; CD14 protein promotes the reaction [lipopeptidophosphoglycan results in increased activity of TLR4 protein] CTD PMID:15910421 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO [lipopeptidophosphoglycan binds to and results in increased activity of TLR2 protein] which results in increased secretion of IL10 protein; [lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL10 protein CTD PMID:15910421 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO [lipopeptidophosphoglycan binds to and results in increased activity of TLR2 protein] which results in increased secretion of IL12B protein; [lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL12B protein CTD PMID:15910421 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [lipopeptidophosphoglycan binds to and results in increased activity of TLR2 protein] results in increased activity of [NFKB1 protein binds to RELA protein]; [lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein] results in increased activity of [NFKB1 protein binds to RELA protein] CTD PMID:15910421 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [lipopeptidophosphoglycan binds to and results in increased activity of TLR2 protein] results in increased activity of [NFKB1 protein binds to RELA protein]; [lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein] results in increased activity of [NFKB1 protein binds to RELA protein] CTD PMID:15910421 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions
increases response to substance		 ISO [lipopeptidophosphoglycan binds to and results in increased activity of TLR2 protein] results in increased activity of [NFKB1 protein binds to RELA protein]; [lipopeptidophosphoglycan binds to and results in increased activity of TLR2 protein] which results in increased secretion of CXCL8 protein; [lipopeptidophosphoglycan binds to and results in increased activity of TLR2 protein] which results in increased secretion of IL10 protein; [lipopeptidophosphoglycan binds to and results in increased activity of TLR2 protein] which results in increased secretion of IL12B protein; [lipopeptidophosphoglycan binds to and results in increased activity of TLR2 protein] which results in increased secretion of TNF protein; CD14 protein promotes the reaction [lipopeptidophosphoglycan results in increased activity of TLR2 protein]; lipopeptidophosphoglycan binds to and results in increased activity of TLR2 protein
TLR2 protein results in increased susceptibility to lipopeptidophosphoglycan		 CTD PMID:15910421 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions
increases response to substance		 ISO [lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein] results in increased activity of [NFKB1 protein binds to RELA protein]; [lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein] which results in increased secretion of CXCL8 protein; [lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL10 protein; [lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL12B protein; [lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein] which results in increased secretion of TNF protein; CD14 protein promotes the reaction [lipopeptidophosphoglycan results in increased activity of TLR4 protein]; lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein
TLR4 protein results in increased susceptibility to lipopeptidophosphoglycan		 CTD PMID:15910421 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [lipopeptidophosphoglycan binds to and results in increased activity of TLR2 protein] which results in increased secretion of TNF protein; [lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein] which results in increased secretion of TNF protein CTD PMID:15910421 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
lysophosphatidic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddr1 discoidin domain receptor tyrosine kinase 1 ISO lysophosphatidic acid increased expression of Ddr1 in 3T3 and GD25 cells RGD PMID:28199848 RGD:151347403 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468 		JBrowse link
lysophosphatidylcholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arntl aryl hydrocarbon receptor nuclear translocator-like affects abundance ISO ARNTL gene mutant form affects the abundance of Lysophosphatidylcholines CTD PMID:27056296 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions		 ISO Lysophosphatidylcholines results in increased expression of CASP3 protein
GPR4 protein promotes the reaction [Lysophosphatidylcholines results in increased expression of CASP3 protein]		 CTD PMID:34293432 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cav1 caveolin 1 multiple interactions
increases expression		 ISO alpha-Tocopherol inhibits the reaction [Lysophosphatidylcholines results in increased expression of CAV1 mRNA]; quercetin 3-O-glucuronide inhibits the reaction [Lysophosphatidylcholines results in increased expression of CAV1 mRNA]; Quercetin inhibits the reaction [Lysophosphatidylcholines results in increased expression of CAV1 mRNA]; Quercetin inhibits the reaction [Lysophosphatidylcholines results in increased expression of CAV1 protein]
Lysophosphatidylcholines results in increased expression of CAV1 mRNA; Lysophosphatidylcholines results in increased expression of CAV1 protein		 CTD PMID:27257344 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 multiple interactions ISO [[Capsaicin results in increased chemical synthesis of Lysophosphatidylcholines] which results in increased secretion of Lysophosphatidylcholines] promotes the reaction [ENPP2 results in increased chemical synthesis of lysophosphatidic acid]; [ENPP2 protein co-treated with Lysophosphatidylcholines] results in increased chemical synthesis of lysophosphatidic acid CTD PMID:19014389 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827 		JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 increases hydrolysis ISO ENPP7 protein results in increased hydrolysis of Lysophosphatidylcholines CTD PMID:12885774 NCBI chr10:104,242,223...104,246,589
Ensembl chr10:104,242,223...104,246,589 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 increases expression ISO Lysophosphatidylcholines results in increased expression of FSCN1 mRNA CTD PMID:22102721 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211 		JBrowse link
G Gja1 gap junction protein, alpha 1 increases ubiquitination
multiple interactions		 EXP Lysophosphatidylcholines results in increased ubiquitination of GJA1 protein
Lysophosphatidylcholines affects the localization of and results in increased phosphorylation of GJA1 protein; PRKCE affects the reaction [Lysophosphatidylcholines results in increased phosphorylation of GJA1 protein]		 CTD PMID:23973256 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gpr4 G protein-coupled receptor 4 increases expression
multiple interactions		 ISO Lysophosphatidylcholines results in increased expression of GPR4 mRNA; Lysophosphatidylcholines results in increased expression of GPR4 protein
GPR4 protein promotes the reaction [Lysophosphatidylcholines results in increased expression of CASP3 protein]; GPR4 protein promotes the reaction [Lysophosphatidylcholines results in increased expression of IL18 protein]; GPR4 protein promotes the reaction [Lysophosphatidylcholines results in increased expression of IL1B protein]; GPR4 protein promotes the reaction [Lysophosphatidylcholines results in increased expression of IL33 protein]; GPR4 protein promotes the reaction [Lysophosphatidylcholines results in increased expression of NLRP3 protein]		 CTD PMID:34293432 NCBI chr 1:78,865,376...78,877,126
Ensembl chr 1:78,865,409...78,876,599 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Lysophosphatidylcholines results in increased expression of HMOX1 mRNA CTD PMID:9808084 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression
multiple interactions		 ISO Lysophosphatidylcholines results in increased expression of ICAM1 mRNA
quercetin 3-O-glucuronide inhibits the reaction [Lysophosphatidylcholines results in increased expression of ICAM1 mRNA]; Quercetin inhibits the reaction [Lysophosphatidylcholines results in increased expression of ICAM1 mRNA]		 CTD PMID:27257344 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Il18 interleukin 18 increases expression
multiple interactions		 ISO Lysophosphatidylcholines results in increased expression of IL18 protein
GPR4 protein promotes the reaction [Lysophosphatidylcholines results in increased expression of IL18 protein]		 CTD PMID:34293432 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions		 ISO Lysophosphatidylcholines results in increased expression of IL1B protein
GPR4 protein promotes the reaction [Lysophosphatidylcholines results in increased expression of IL1B protein]		 CTD PMID:34293432 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il33 interleukin 33 increases expression
multiple interactions		 ISO Lysophosphatidylcholines results in increased expression of IL33 protein
GPR4 protein promotes the reaction [Lysophosphatidylcholines results in increased expression of IL33 protein]		 CTD PMID:34293432 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Lama3 laminin subunit alpha 3 increases expression ISO Lysophosphatidylcholines results in increased expression of LAMA3 mRNA CTD PMID:15541073 NCBI chr18:3,523,168...3,751,722
Ensembl chr18:3,523,133...3,751,353 		JBrowse link
G Lamb3 laminin subunit beta 3 increases expression ISO Lysophosphatidylcholines results in increased expression of LAMB3 mRNA CTD PMID:15541073 NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405 		JBrowse link
G Lamc2 laminin subunit gamma 2 increases expression ISO Lysophosphatidylcholines results in increased expression of LAMC2 mRNA CTD PMID:15541073 NCBI chr13:65,284,664...65,344,200
Ensembl chr13:65,284,664...65,344,200 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Lysophosphatidylcholines results in increased phosphorylation of MAPK1 protein]; resveratrol inhibits the reaction [Lysophosphatidylcholines results in increased phosphorylation of MAPK1 protein] CTD PMID:20564508 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Lysophosphatidylcholines results in increased phosphorylation of MAPK3 protein]; resveratrol inhibits the reaction [Lysophosphatidylcholines results in increased phosphorylation of MAPK3 protein] CTD PMID:20564508 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mfsd2a major facilitator superfamily domain containing 2A increases transport ISO MFSD2A results in increased transport of Lysophosphatidylcholines CTD PMID:26005865 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression		 ISO GPR4 protein promotes the reaction [Lysophosphatidylcholines results in increased expression of NLRP3 protein] CTD PMID:34293432 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Lysophosphatidylcholines results in increased expression of NOS2 mRNA]; Resveratrol inhibits the reaction [Lysophosphatidylcholines results in increased expression of NOS2 mRNA] CTD PMID:20564508 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
decreases expression		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Lysophosphatidylcholines results in decreased expression of NOS3 mRNA]; resveratrol inhibits the reaction [Lysophosphatidylcholines results in decreased expression of NOS3 mRNA] CTD PMID:20564508 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 multiple interactions ISO [NR5A2 gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of Lysophosphatidylcholines CTD PMID:29515023 NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326 		JBrowse link
G Pah phenylalanine hydroxylase multiple interactions ISO Lysophosphatidylcholines results in increased activity of [PAH protein binds to PAH protein binds to PAH protein binds to PAH protein] CTD PMID:19367645 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130 		JBrowse link
G Prkce protein kinase C, epsilon multiple interactions EXP PRKCE affects the reaction [Lysophosphatidylcholines results in increased phosphorylation of GJA1 protein] CTD PMID:23973256 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression
multiple interactions		 EXP Lysophosphatidylcholines results in decreased expression of PTGS1 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Lysophosphatidylcholines results in decreased expression of PTGS1 mRNA]; resveratrol inhibits the reaction [Lysophosphatidylcholines results in decreased expression of PTGS1 mRNA]		 CTD PMID:20564508 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Lysophosphatidylcholines results in increased expression of PTGS2 mRNA]; resveratrol inhibits the reaction [Lysophosphatidylcholines results in increased expression of PTGS2 mRNA] CTD PMID:20564508 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased abundance of Lysophosphatidylcholines CTD PMID:30258081 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trpc5 transient receptor potential cation channel, subfamily C, member 5 multiple interactions ISO Lysophosphatidylcholines promotes the reaction [TRPC5 protein results in increased transport of Calcium]; resveratrol inhibits the reaction [Lysophosphatidylcholines promotes the reaction [TRPC5 protein results in increased transport of Calcium]] CTD PMID:21127073 NCBI chr  X:107,946,163...108,230,978
Ensembl chr  X:107,939,131...108,230,991 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression ISO Lysophosphatidylcholines results in increased expression of VCAM1 mRNA CTD PMID:27257344 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
lysophosphatidylethanolamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions ISO lysophosphatidylethanolamine analog inhibits the reaction [cobaltous chloride results in decreased expression of BIRC3 protein] CTD PMID:25125499 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO lysophosphatidylethanolamine analog inhibits the reaction [cobaltous chloride results in increased activity of CASP3 protein]
lysophosphatidylethanolamine analog inhibits the reaction [Glycochenodeoxycholic Acid results in increased cleavage of CASP3 protein]		 CTD PMID:25125499 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions
increases expression		 ISO lysophosphatidylethanolamine analog inhibits the reaction [cobaltous chloride results in decreased expression of CFLAR mRNA]
lysophosphatidylethanolamine analog results in increased expression of CFLAR protein
Glycochenodeoxycholic Acid promotes the reaction [lysophosphatidylethanolamine analog results in increased expression of CFLAR protein]; lysophosphatidylethanolamine analog promotes the reaction [Glycochenodeoxycholic Acid results in increased expression of CFLAR protein]
lysophosphatidylethanolamine analog results in increased expression of CFLAR mRNA; lysophosphatidylethanolamine analog results in increased expression of CFLAR protein		 CTD PMID:25125499 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO [lysophosphatidylethanolamine analog co-treated with cobaltous chloride] results in increased phosphorylation of GSK3B protein CTD PMID:25125499 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions
increases expression		 ISO lysophosphatidylethanolamine analog inhibits the reaction [cobaltous chloride results in decreased expression of and results in increased degradation of MCL1 protein]
lysophosphatidylethanolamine analog results in increased expression of MCL1 protein
lysophosphatidylethanolamine analog inhibits the reaction [Glycochenodeoxycholic Acid results in decreased expression of and results in increased degradation of MCL1 protein]		 CTD PMID:25125499 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 multiple interactions ISO [NR5A2 gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of lysophosphatidylethanolamine; [NR5A2 gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of lysophosphatidylethanolamine analog CTD PMID:29515023 NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO lysophosphatidylethanolamine analog inhibits the reaction [cobaltous chloride results in increased activity of PARP1 protein] CTD PMID:25125499 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased abundance of lysophosphatidylethanolamine CTD PMID:30258081 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
lysophosphatidylglycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pon1 paraoxonase 1 decreases activity
multiple interactions		 ISO lysophosphatidylglycerol results in decreased activity of PON1 protein
lysophosphatidylglycerol inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon]		 CTD PMID:15375178 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
phosphatidic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen increases abundance EXP AGT protein results in increased abundance of Phosphatidic Acids CTD PMID:14613874 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO
EXP		 alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Phosphatidic Acids results in increased phosphorylation of AKT1 protein]
R 59949 inhibits the reaction [Phosphatidic Acids results in increased phosphorylation of AKT1 protein]		 CTD PMID:15525798 PMID:16354768 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Avp arginine vasopressin increases abundance
multiple interactions		 EXP AVP protein results in increased abundance of Phosphatidic Acids
2-(4-amylcinnamoyl)amino-4-chlorobenzoic acid inhibits the reaction [AVP protein results in increased abundance of Phosphatidic Acids]		 CTD PMID:11356622 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases activity ISO Phosphatidic Acids results in increased activity of BGLAP protein CTD PMID:16857255 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Egf epidermal growth factor multiple interactions
increases abundance		 EXP 1-Butanol inhibits the reaction [EGF protein results in increased abundance of Phosphatidic Acids] CTD PMID:11134345 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase increases activity ISO Phosphatidic Acids results in increased activity of FGR protein CTD PMID:11078731 NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases secretion		 ISO alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Phosphatidic Acids results in increased secretion of IL1B protein] CTD PMID:16354768 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion		 ISO alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Phosphatidic Acids results in increased secretion of IL6 protein] CTD PMID:16354768 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Jak2 Janus kinase 2 increases phosphorylation ISO Phosphatidic Acids results in increased phosphorylation of JAK2 protein CTD PMID:16354768 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Phosphatidic Acids inhibits the reaction [Ethanol results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]; Phosphatidic Acids results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [Phosphatidic Acids results in increased phosphorylation of and results in increased activity of MAPK1 protein] CTD PMID:18358832 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Phosphatidic Acids inhibits the reaction [Ethanol results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]; Phosphatidic Acids results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [Phosphatidic Acids results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:18358832 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mmp2 matrix metallopeptidase 2 increases activity
multiple interactions		 ISO Phosphatidic Acids results in increased activity of MMP2 protein
Quercetin inhibits the reaction [Phosphatidic Acids results in increased activity of MMP2 protein]		 CTD PMID:21867678 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
increases activity		 ISO MTOR protein affects the reaction [Phosphatidic Acids results in increased activity of RPS6KB2 protein]
Phosphatidic Acids results in increased activity of MTOR protein		 CTD PMID:12087098 PMID:16537399 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions EXP [1-Butanol inhibits the reaction [PLD2 protein results in increased chemical synthesis of Phosphatidic Acids]] affects the reaction [PENK protein binds to and results in increased activity of OPRM1 protein] CTD PMID:14720217 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Penk proenkephalin multiple interactions EXP [1-Butanol inhibits the reaction [PLD2 protein results in increased chemical synthesis of Phosphatidic Acids]] affects the reaction [PENK protein binds to and results in increased activity of OPRM1 protein] CTD PMID:14720217 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129 		JBrowse link
G Pld1 phospholipase D1 increases activity ISO Phosphatidic Acids results in increased activity of PLD1 protein CTD PMID:16857255 NCBI chr 2:110,849,205...111,047,692
Ensembl chr 2:110,893,608...111,047,692 		JBrowse link
G Pld2 phospholipase D2 multiple interactions EXP 1-Butanol inhibits the reaction [PLD2 protein results in increased chemical synthesis of Phosphatidic Acids]; [1-Butanol inhibits the reaction [PLD2 protein results in increased chemical synthesis of Phosphatidic Acids]] affects the reaction [PENK protein binds to and results in increased activity of OPRM1 protein] CTD PMID:14720217 NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808 		JBrowse link
G Prkcz protein kinase C, zeta increases activity
multiple interactions		 EXP
ISO		 Phosphatidic Acids results in increased activity of PRKCZ protein
Phosphatidic Acids results in increased phosphorylation of and results in increased activity of PRKCZ protein		 CTD PMID:11978788 PMID:15255942 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Phosphatidic Acids results in increased expression of PTGS2 protein
Phosphatidic Acids results in increased expression of PTGS2 mRNA		 CTD PMID:12872987 PMID:15210717 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions ISO Phosphatidic Acids results in increased phosphorylation of and results in increased activity of RPS6KB1 protein CTD PMID:15255942 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Rps6kb2 ribosomal protein S6 kinase B2 multiple interactions
increases activity		 ISO MTOR protein affects the reaction [Phosphatidic Acids results in increased activity of RPS6KB2 protein]; Sirolimus inhibits the reaction [Phosphatidic Acids results in increased activity of RPS6KB2 protein]; wortmannin inhibits the reaction [Phosphatidic Acids results in increased activity of RPS6KB2 protein] CTD PMID:12087098 NCBI chr 1:201,451,265...201,458,096
Ensembl chr 1:201,451,265...201,458,078 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO Phosphatidic Acids results in increased phosphorylation of and affects the localization of STAT1 protein CTD PMID:16354768 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO Phosphatidic Acids results in increased phosphorylation of and affects the localization of STAT3 protein CTD PMID:16354768 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Sts steroid sulfatase multiple interactions ISO Phosphatidic Acids promotes the reaction [Tretinoin results in increased activity of STS protein] CTD PMID:16178010 NCBI chr  X:42,225,131...42,233,403
Ensembl chr  X:42,225,372...42,233,402 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases secretion		 ISO TNF protein inhibits the reaction [Carbachol results in increased abundance of Phosphatidic Acids]
Phosphatidic Acids results in increased secretion of TNF protein		 CTD PMID:11245595 PMID:16354768 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
phosphatidylcholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 increases secretion ISO ABCB11 protein results in increased secretion of Phosphatidylcholines CTD PMID:14570929 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects export
affects transport		 ISO ABCB1 protein affects the export of Phosphatidylcholines
ABCB1 protein affects the transport of Phosphatidylcholines		 CTD PMID:11147995 PMID:11745043 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 affects transport
affects export		 ISO ABCB4 protein affects the transport of Phosphatidylcholines
ABCB4 protein affects the export of Phosphatidylcholines		 CTD PMID:11745043 PMID:15696852 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 decreases activity EXP Phosphatidylcholines results in decreased activity of ACAT1 protein CTD PMID:12559476 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression ISO Phosphatidylcholines results in decreased expression of ADIPOQ mRNA CTD PMID:23911798 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases abundance		 ISO PEMT protein promotes the reaction [AHR protein results in increased abundance of Phosphatidylcholines] CTD PMID:29416063 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions ISO [rubitecan co-treated with Phosphatidylcholines] results in increased expression of AIFM1 protein CTD PMID:21695227 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G App amyloid beta precursor protein multiple interactions ISO [[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide; [[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines; Edetic Acid inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide]; Penicillamine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide]; Trientine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide] CTD PMID:17964426 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like increases abundance ISO ARNTL gene mutant form results in increased abundance of Phosphatidylcholines CTD PMID:27056296 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G As3mt arsenite methyltransferase affects metabolic processing ISO AS3MT gene mutant form affects the metabolism of Phosphatidylcholines CTD PMID:27591999 NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [rubitecan co-treated with Phosphatidylcholines] results in increased expression of BAX protein CTD PMID:21695227 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [rubitecan co-treated with Phosphatidylcholines] results in decreased expression of BCL2 protein CTD PMID:21695227 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Casp3 caspase 3 multiple interactions ISO [rubitecan co-treated with Phosphatidylcholines] results in increased expression of CASP3 protein CTD PMID:21695227 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO [rubitecan co-treated with Phosphatidylcholines] results in increased expression of CASP8 protein CTD PMID:21695227 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO [rubitecan co-treated with Phosphatidylcholines] results in increased expression of CASP9 protein CTD PMID:21695227 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Phosphatidylcholines results in increased expression of CCL2 mRNA CTD PMID:23911798 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [rubitecan co-treated with Phosphatidylcholines] results in decreased expression of CCND1 protein CTD PMID:21695227 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccne1 cyclin E1 multiple interactions ISO Phosphatidylcholines promotes the reaction [rubitecan results in decreased expression of CCNE1 protein] CTD PMID:21695227 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO [rubitecan co-treated with Phosphatidylcholines] results in decreased expression of CDK2 protein CTD PMID:21695227 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [rubitecan co-treated with Phosphatidylcholines] results in increased expression of CDKN1A protein CTD PMID:21695227 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO [rubitecan co-treated with Phosphatidylcholines] results in increased expression of CDKN1B protein CTD PMID:21695227 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Ces1d carboxylesterase 1D decreases expression ISO Phosphatidylcholines results in decreased expression of CES1D mRNA CTD PMID:23911798 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP [silybin co-treated with Phosphatidylcholines co-treated with Vitamin E] inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A1 mRNA] CTD PMID:16169303 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Crp C-reactive protein affects binding
decreases activity		 ISO CRP protein binds to Phosphatidylcholines
Phosphatidylcholines results in decreased activity of CRP protein		 CTD PMID:16962105 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects activity ISO Phosphatidylcholines affects the activity of CYP1A2 protein CTD PMID:15966743 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases activity EXP Phosphatidylcholines results in increased activity of CYP7A1 protein CTD PMID:12559476 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 increases hydrolysis ISO ENPP7 protein results in increased hydrolysis of Phosphatidylcholines CTD PMID:12885774 NCBI chr10:104,242,223...104,246,589
Ensembl chr10:104,242,223...104,246,589 		JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [orlistat results in decreased activity of FASN protein] which results in decreased abundance of Phosphatidylcholines CTD PMID:18723500 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fgf19 fibroblast growth factor 19 decreases abundance ISO FGF19 protein results in decreased abundance of Phosphatidylcholines CTD PMID:29416063 NCBI chr 1:200,056,656...200,059,944
Ensembl chr 1:200,056,644...200,060,287 		JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions ISO GPX4 mutant form promotes the reaction [TNF protein results in increased abundance of Phosphatidylcholines metabolite]; GPX4 protein inhibits the reaction [TNF protein results in increased abundance of Phosphatidylcholines metabolite] CTD PMID:22433871 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases activity EXP Phosphatidylcholines results in increased activity of HMGCR protein CTD PMID:12559476 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Igf1 insulin-like growth factor 1 increases degradation ISO IGF1 protein results in increased degradation of Phosphatidylcholines CTD PMID:2120207 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Il10 interleukin 10 increases expression ISO Phosphatidylcholines results in increased expression of IL10 mRNA CTD PMID:23911798 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions		 ISO Phosphatidylcholines results in increased expression of IL1B mRNA
Phosphatidylcholines results in increased expression of and results in increased secretion of IL1B protein		 CTD PMID:23911798 PMID:30958839 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 increases expression ISO Phosphatidylcholines results in increased expression of IL6 mRNA CTD PMID:23911798 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Lep leptin decreases expression ISO Phosphatidylcholines results in decreased expression of LEP mRNA CTD PMID:23911798 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lipc lipase C, hepatic type multiple interactions
increases abundance		 ISO [LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of Phosphatidylcholines
LIPC gene mutant form results in increased abundance of Phosphatidylcholines		 CTD PMID:24777581 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464 		JBrowse link
G Lipe lipase E, hormone sensitive type increases expression ISO Phosphatidylcholines results in increased expression of LIPE mRNA CTD PMID:23911798 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310 		JBrowse link
G Lipg lipase G, endothelial type multiple interactions
increases abundance		 ISO [LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of Phosphatidylcholines
LIPG gene mutant form results in increased abundance of Phosphatidylcholines		 CTD PMID:24777581 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260 		JBrowse link
G Ltf lactotransferrin multiple interactions ISO [LTF protein co-treated with Phosphatidylcholines co-treated with Phytosterols] inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:16141546 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP [silybin co-treated with Phosphatidylcholines co-treated with Vitamin E] inhibits the reaction [Dimethylnitrosamine results in increased expression of MMP2 mRNA] CTD PMID:16169303 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions ISO NOX4 mutant form inhibits the reaction [TNF protein results in increased abundance of Phosphatidylcholines metabolite] CTD PMID:22433871 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases abundance ISO NR0B2 protein results in decreased abundance of Phosphatidylcholines CTD PMID:29416063 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609 		JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 multiple interactions ISO [NR5A2 gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of Phosphatidylcholines CTD PMID:29515023 NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326 		JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 multiple interactions
increases secretion		 EXP PAFAH1B1 protein promotes the reaction [Terbutaline results in increased secretion of Phosphatidylcholines]; PAFAH1B1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of Phosphatidylcholines]
PAFAH1B1 protein results in increased secretion of Phosphatidylcholines		 CTD PMID:12013527 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808 		JBrowse link
G Pafah2 platelet-activating factor acetylhydrolase 2 multiple interactions ISO PAFAH2 inhibits the reaction [TNF protein results in increased abundance of Phosphatidylcholines metabolite] CTD PMID:22433871 NCBI chr 5:146,607,050...146,636,203
Ensembl chr 5:146,613,498...146,634,943 		JBrowse link
G Pcyt1a phosphate cytidylyltransferase 1A, choline multiple interactions ISO PCYT1A protein promotes the reaction [PLPP6 protein results in increased chemical synthesis of Phosphatidylcholines] CTD PMID:18930839 NCBI chr11:68,313,860...68,357,828
Ensembl chr11:68,313,882...68,357,357 		JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase multiple interactions ISO PEMT protein promotes the reaction [AHR protein results in increased abundance of Phosphatidylcholines] CTD PMID:29416063 NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013 		JBrowse link
G Plin1 perilipin 1 increases expression ISO Phosphatidylcholines results in increased expression of PLIN1 mRNA CTD PMID:23911798 NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828 		JBrowse link
G Plpp6 phospholipid phosphatase 6 multiple interactions
increases chemical synthesis		 ISO PCYT1A protein promotes the reaction [PLPP6 protein results in increased chemical synthesis of Phosphatidylcholines] CTD PMID:18930839 NCBI chr 1:226,679,100...226,681,952
Ensembl chr 1:226,679,100...226,681,949 		JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 decreases expression ISO Phosphatidylcholines results in decreased expression of PNPLA2 mRNA CTD PMID:23911798 NCBI chr 1:196,552,723...196,557,805
Ensembl chr 1:196,552,723...196,557,805 		JBrowse link
G Pon2 paraoxonase 2 increases activity
increases expression		 ISO Phosphatidylcholines results in increased activity of PON2 protein
Phosphatidylcholines results in increased expression of PON2 mRNA		 CTD PMID:12615656 NCBI chr 4:33,389,702...33,425,186
Ensembl chr 4:33,389,714...33,425,248 		JBrowse link
G Pon3 paraoxonase 3 multiple interactions ISO Phosphatidylcholines inhibits the reaction [PON3 protein results in increased metabolism of Lovastatin] CTD PMID:12615656 NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO Phosphatidylcholines results in increased expression of PPARG mRNA CTD PMID:23911798 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppargc1b PPARG coactivator 1 beta increases abundance ISO PPARGC1B results in increased abundance of Phosphatidylcholines CTD PMID:17932310 NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194 		JBrowse link
G Pten phosphatase and tensin homolog affects binding
multiple interactions		 ISO PTEN protein binds to Phosphatidylcholines
[TXN protein binds to PTEN protein] inhibits the reaction [PTEN protein binds to Phosphatidylcholines]		 CTD PMID:15313215 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Retn resistin decreases expression ISO Phosphatidylcholines results in decreased expression of RETN mRNA CTD PMID:23911798 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620 		JBrowse link
G Sftpa1 surfactant protein A1 multiple interactions ISO [SFTPA1 protein polymorphism binds to SFTPA2 protein polymorphism] inhibits the reaction [Adenosine Triphosphate results in increased secretion of Phosphatidylcholines]; Ozone inhibits the reaction [[SFTPA1 protein polymorphism binds to SFTPA2 protein polymorphism] inhibits the reaction [Adenosine Triphosphate results in increased secretion of Phosphatidylcholines]]; Ozone inhibits the reaction [SFTPA1 protein polymorphism inhibits the reaction [Adenosine Triphosphate results in increased secretion of Phosphatidylcholines]] CTD PMID:15065867 NCBI chr16:17,008,180...17,011,686
Ensembl chr16:17,008,180...17,011,685 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP [silybin co-treated with Phosphatidylcholines co-treated with Vitamin E] inhibits the reaction [Dimethylnitrosamine results in increased expression of TGFB1 mRNA] CTD PMID:16169303 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP [silybin co-treated with Phosphatidylcholines co-treated with Vitamin E] inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA] CTD PMID:16169303 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
increases abundance		 ISO GPX4 mutant form promotes the reaction [TNF protein results in increased abundance of Phosphatidylcholines metabolite]; GPX4 protein inhibits the reaction [TNF protein results in increased abundance of Phosphatidylcholines metabolite]; NOX4 mutant form inhibits the reaction [TNF protein results in increased abundance of Phosphatidylcholines metabolite]; PAFAH2 inhibits the reaction [TNF protein results in increased abundance of Phosphatidylcholines metabolite]
Phosphatidylcholines results in increased expression of TNF mRNA
[LTF protein co-treated with Phosphatidylcholines co-treated with Phytosterols] inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Phosphatidylcholines results in increased expression of and results in increased secretion of TNF protein		 CTD PMID:16141546 PMID:22433871 PMID:23911798 PMID:30958839 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO Phosphatidylcholines inhibits the reaction [rubitecan results in increased expression of TP53 protein] CTD PMID:21695227 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Txn1 thioredoxin 1 multiple interactions ISO [TXN protein binds to PTEN protein] inhibits the reaction [PTEN protein binds to Phosphatidylcholines] CTD PMID:15313215 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
phosphatidylethanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plek pleckstrin multiple interactions ISO phosphatidylethanol analog promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased phosphorylation of PLEK protein] CTD PMID:8928743 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131 		JBrowse link
phosphatidylethanolamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor decreases abundance ISO AHR protein results in decreased abundance of phosphatidylethanolamine CTD PMID:29416063 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO phosphatidylethanolamine results in increased stability of and results in increased activity of CYP1A2 protein CTD PMID:15966743 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Fgf19 fibroblast growth factor 19 increases abundance ISO FGF19 protein results in increased abundance of phosphatidylethanolamine CTD PMID:29416063 NCBI chr 1:200,056,656...200,059,944
Ensembl chr 1:200,056,644...200,060,287 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO calpeptin inhibits the reaction [dehydroeburicoic acid promotes the reaction [MAP1LC3B protein binds to phosphatidylethanolamine]]; dehydroeburicoic acid promotes the reaction [MAP1LC3B protein binds to phosphatidylethanolamine] CTD PMID:19848398 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Ppargc1b PPARG coactivator 1 beta increases abundance ISO PPARGC1B results in increased abundance of phosphatidylethanolamine CTD PMID:17932310 NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194 		JBrowse link
G Pten phosphatase and tensin homolog multiple interactions
affects binding		 ISO [TXN protein binds to PTEN protein] inhibits the reaction [PTEN protein binds to phosphatidylethanolamine] CTD PMID:15313215 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Txn1 thioredoxin 1 multiple interactions ISO [TXN protein binds to PTEN protein] inhibits the reaction [PTEN protein binds to phosphatidylethanolamine] CTD PMID:15313215 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
phosphatidylinositol 4-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2 coagulation factor II multiple interactions
increases abundance		 ISO resveratrol inhibits the reaction [F2 protein results in increased abundance of phosphatidylinositol 4-phosphate] CTD PMID:16051184 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Ncs1 neuronal calcium sensor 1 increases phosphorylation
multiple interactions		 EXP NCS1 protein results in increased phosphorylation of phosphatidylinositol 4-phosphate
wortmannin inhibits the reaction [NCS1 protein results in increased phosphorylation of phosphatidylinositol 4-phosphate]		 CTD PMID:12471042 NCBI chr 3:14,523,220...14,568,829
Ensembl chr 3:14,523,220...14,568,829 		JBrowse link
phosphatidylinositol dimannoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 multiple interactions ISO [phosphatidylinositol dimannoside analog co-treated with Thioglycolates] results in increased expression of IL6 protein; phosphatidylinositol dimannoside analog inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of IL6 protein]; phosphatidylinositol dimannoside analog promotes the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of IL6 protein]; TLR4 gene mutant form inhibits the reaction [[phosphatidylinositol dimannoside analog co-treated with Thioglycolates] results in increased expression of IL6 protein] CTD PMID:21936536 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO TLR4 gene mutant form inhibits the reaction [[phosphatidylinositol dimannoside analog co-treated with Thioglycolates] results in increased expression of IL6 protein] CTD PMID:21936536 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
rac-1-monolauroylglycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iyd iodotyrosine deiodinase multiple interactions ISO 1-monomyristin inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319 		JBrowse link
triacetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Biofuels co-treated with Triacetin] results in decreased expression of BCL2 mRNA CTD PMID:30738890 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Biofuels co-treated with Triacetin] results in decreased expression of CASP3 mRNA CTD PMID:30738890 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [Biofuels co-treated with Triacetin] affects the expression of CYP1A1 mRNA CTD PMID:30738890 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Triacetin results in increased expression of DDIT3 mRNA CTD PMID:21703327 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [Biofuels co-treated with Triacetin] affects the expression of HMOX1 mRNA CTD PMID:30738890 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
triarachidonin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scd stearoyl-CoA desaturase decreases expression
multiple interactions		 ISO Triarachidonin results in decreased expression of SCD1 mRNA
Clofibrate inhibits the reaction [Triarachidonin results in decreased expression of SCD1 mRNA]		 CTD PMID:8729090 PMID:8790349 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
tributyrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator decreases expression ISO tributyrin results in decreased expression of BCL2 mRNA CTD PMID:11876963 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Cd86 CD86 molecule increases expression ISO tributyrin results in increased expression of CD86 protein CTD PMID:30503584 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Ifng interferon gamma multiple interactions ISO [tributyrin co-treated with Fluorescein-5-isothiocyanate] results in increased secretion of IFNG protein CTD PMID:29198882 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO tributyrin results in increased expression of IL1B protein CTD PMID:30503584 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO IL2 protein affects the reaction [tributyrin affects the phosphorylation of MAPK1 protein]; IL2 protein affects the reaction [tributyrin affects the phosphorylation of MAPK3 protein] CTD PMID:16252257 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO [tributyrin co-treated with Fluorescein-5-isothiocyanate] results in increased secretion of IL4 protein CTD PMID:29198882 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 affects phosphorylation
multiple interactions		 ISO tributyrin affects the phosphorylation of MAPK1 protein
IL2 protein affects the reaction [tributyrin affects the phosphorylation of MAPK1 protein]		 CTD PMID:16252257 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
affects phosphorylation		 ISO IL2 protein affects the reaction [tributyrin affects the phosphorylation of MAPK3 protein] CTD PMID:16252257 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions EXP tributyrin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR2 mRNA] CTD PMID:21051124 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP tributyrin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:21051124 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO tributyrin results in increased activity of TRPA1 protein CTD PMID:29198882 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570 		JBrowse link
triolein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO Triolein results in decreased expression of ABCA1 mRNA CTD PMID:18356535 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 decreases expression ISO Triolein results in decreased expression of ABCG5 mRNA CTD PMID:18356535 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 decreases expression ISO Triolein results in decreased expression of ABCG8 mRNA CTD PMID:18356535 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of ACACA mRNA]]; Triolein promotes the reaction [Fructose results in increased expression of ACACA mRNA] CTD PMID:15066988 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Apoa4 apolipoprotein A4 multiple interactions EXP [Taurocholic Acid co-treated with Triolein co-treated with Lecithins] results in increased expression of APOA4 protein CTD PMID:6631239 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Apoe apolipoprotein E multiple interactions EXP [Taurocholic Acid co-treated with Triolein co-treated with Lecithins] results in decreased expression of APOE protein CTD PMID:6631239 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G App amyloid beta precursor protein multiple interactions EXP Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of APP protein alternative form]; Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of APP protein] CTD PMID:28734741 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Cat catalase multiple interactions EXP Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of CAT mRNA] CTD PMID:28734741 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression ISO Triolein results in decreased expression of CYP27A1 mRNA CTD PMID:18356535 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Fasn fatty acid synthase multiple interactions ISO Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of FASN mRNA]]; Triolein promotes the reaction [Fructose results in increased expression of FASN mRNA] CTD PMID:15066988 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of GPX1 mRNA] CTD PMID:28734741 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO Triolein results in increased expression of HMGCR mRNA CTD PMID:18356535 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Mttp microsomal triglyceride transfer protein increases expression ISO Triolein results in increased expression of MTTP mRNA CTD PMID:18356535 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239 		JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 decreases expression ISO Triolein results in decreased expression of NPC1L1 mRNA CTD PMID:18356535 NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113 		JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased abundance of Triglycerides]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of ACACA mRNA]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of FASN mRNA]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 mRNA]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 protein]] CTD PMID:15066988 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of SOD1 mRNA] CTD PMID:28734741 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of SOD2 mRNA] CTD PMID:28734741 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 mRNA]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 protein]] CTD PMID:15066988 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
very-low-density lipoprotein triglyceride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf21 fibroblast growth factor 21 multiple interactions
decreases secretion		 ISO FGF21 gene mutant form inhibits the reaction [Fructose results in increased secretion of very low density lipoprotein triglyceride]
FGF21 gene mutant form results in decreased secretion of very low density lipoprotein triglyceride		 CTD PMID:28123933 NCBI chr 1:96,083,495...96,084,738
Ensembl chr 1:96,083,441...96,090,454 		JBrowse link
G Lpl lipoprotein lipase increases hydrolysis
multiple interactions
increases activity		 ISO LPL protein results in increased hydrolysis of very low density lipoprotein triglyceride
[LPL protein results in increased hydrolysis of very low density lipoprotein triglyceride] which results in increased abundance of Fatty Acids, Unsaturated; orlistat inhibits the reaction [very low density lipoprotein triglyceride results in increased activity of LPL protein]; very low density lipoprotein triglyceride affects the reaction [LPL protein results in decreased activity of TNF protein]		 CTD PMID:12573449 PMID:15994321 PMID:18435438 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Lrp1 LDL receptor related protein 1 multiple interactions ISO very low density lipoprotein triglyceride promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of LRP1 mRNA] CTD PMID:15910848 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G Mb myoglobin multiple interactions
decreases secretion		 EXP alpha-Tocopherol inhibits the reaction [MB modified form results in decreased secretion of very low density lipoprotein triglyceride] CTD PMID:17478120 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383 		JBrowse link
G Ppargc1b PPARG coactivator 1 beta increases abundance ISO PPARGC1B results in increased abundance of very low density lipoprotein triglyceride CTD PMID:17932310 NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194 		JBrowse link
G Sirt7 sirtuin 7 decreases secretion ISO SIRT7 gene mutant form results in decreased secretion of very low density lipoprotein triglyceride CTD PMID:24210820 NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO very low density lipoprotein triglyceride affects the reaction [LPL protein results in decreased activity of TNF protein] CTD PMID:15994321 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20056
    role 20008
      biological role 20007
        osmolyte 2067
          glycerol 1786
            glycerolipid 280
              (11Z)-icosenoyl-containing glycerolipid 0
              (11Z,14Z)-icosadienoyl-containing glycerolipid 0
              (11Z,14Z,17Z)-icosatrienoyl-containing glycerolipid 0
              (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-containing glycerolipid 0
              (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-containing glycerolipid 0
              (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-containing glycerolipid 0
              (5Z,9Z,12Z)-octadecatrienoyl-containing glycerolipid 0
              (5Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid 0
              (6Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid 0
              (7Z,10Z)-hexadecadienoyl-containing glycerolipid 0
              (7Z,10Z,13Z)-hexadecatrienoyl-containing glycerolipid 0
              (7Z,10Z,13Z,16Z)-docosatetraenoyl-containing glycerolipid 0
              (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-containing glycerolipid 0
              (8E,10E,12Z)-octadecatrienoyl-containing glycerolipid 0
              (8Z,11Z)-icosadienoyl-containing glycerolipid 0
              (8Z,11Z,14Z)-icosatrienoyl-containing glycerolipid 0
              (9Z)-octadec-9-en-12-ynoyl-containing glycerolipid 0
              (9Z,11E,13E)-octadecatrienoyl-containing glycerolipid 0
              (9Z,11E,13E,15Z)-octadecatetraenoyl-containing glycerolipid 0
              (9Z,11E,13Z)-octadeca-9,11,13-trienoyl-containing glycerolipid 0
              (9Z,12E)-hexadecadienoyl-containing glycerolipid 0
              (9Z,12E)-octadecadienoyl-containing glycerolipid 0
              (9Z,12Z)-octadeca-9,12-dien-6-ynoyl-containing glycerolipid 0
              (9Z,12Z,15Z)-octadeca-9,12,15-trien-6-ynoyl-containing glycerolipid 0
              1(3)-O-(alk-1-enyl)-glycerol + 0
              1,2,3-Tris(1-ethoxyethoxy)propane 0
              1,2-di-O-stearoyl-3-S-\{2-[(2-\{beta-D-Glcp-(1->4)-[beta-D-Glcp-(1->4)-beta-D-Glcp-(1->6)]-beta-D-GlcpNAc-1-O-yl\}ethyl)amino]-2-oxoethyl\}monothioglycerol 0
              1,2-diacyl-sn-glycerolipid + 0
              1-(1,2-saturated-acyl)-2-acyl-sn-glycerolipid + 0
              1-O-(alk-1-enyl)-2-acyl-sn-glycerolipid + 0
              1-[(6Z,9Z,12Z,15Z)-octadec-6,9,12,15-tetraenoyl]-2-acylglycerolipid 0
              1-acyl-2-[(3E)-hexadec-3-enoyl]-glycerolipid 0
              1-acyl-2-[(7Z)-hexadec-7-enoyl]-glycerolipid 0
              1-acyl-2-alkylglycerol + 0
              1-acyl-2-palmitoleoylglycerolipid 0
              1-acyl-2-palmitoylglycerolipid 0
              1-alkenyl-2-acylglycerol 0
              1-alkyl-2-acetylglycerol + 0
              1-alkyl-2-acylglycerol + 0
              1-linoleoyl-2-acylglycerolipid 0
              1-oleoyl-2-acylglycerolipid 0
              1-radyl-2-acyl-sn-glycerolipid + 0
              1-stearoyl 2-acylglycerolipid 0
              alk-1-enylacylglycerol + 0
              alkyldiacylglycerol + 0
              alpha-linolenoyl-containing glycerolipid + 0
              arachidonoyl-containing glycerolipid 0
              dihexosyldiradylglycerol + 0
              diradylglycerol + 24
              gamma-linolenoyl-containing glycerolipid + 0
              glyceride + 104
              glycerophospholipid + 209
              glycerophosphonolipid + 0
              glycosyldiradylglycerol + 0
              glycosylmonoradylglycerol + 0
              linoleoyl-containing glycerolipid 0
              monoalkyldiacylglycerol + 0
              monohexosyldiradylglycerol + 0
              monoradylglycerol + 53
              monothioglycerolipid + 0
              oleoyl-containing glycerolipid 0
              omega-3-arachidonoyl-containing glycerolipid 0
              palmitoleoyl-containing glycerolipid 0
              triradylglycerol + 40
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19875
                          organic molecular entity 19875
                            heteroorganic entity 19561
                              organochalcogen compound 19310
                                organooxygen compound 19243
                                  carbohydrates and carbohydrate derivatives 13928
                                    carbohydrate 13928
                                      alditol 1905
                                        glycerol 1786
                                          glycerolipid 280
                                            (11Z)-icosenoyl-containing glycerolipid 0
                                            (11Z,14Z)-icosadienoyl-containing glycerolipid 0
                                            (11Z,14Z,17Z)-icosatrienoyl-containing glycerolipid 0
                                            (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-containing glycerolipid 0
                                            (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-containing glycerolipid 0
                                            (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-containing glycerolipid 0
                                            (5Z,9Z,12Z)-octadecatrienoyl-containing glycerolipid 0
                                            (5Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid 0
                                            (6Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid 0
                                            (7Z,10Z)-hexadecadienoyl-containing glycerolipid 0
                                            (7Z,10Z,13Z)-hexadecatrienoyl-containing glycerolipid 0
                                            (7Z,10Z,13Z,16Z)-docosatetraenoyl-containing glycerolipid 0
                                            (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-containing glycerolipid 0
                                            (8E,10E,12Z)-octadecatrienoyl-containing glycerolipid 0
                                            (8Z,11Z)-icosadienoyl-containing glycerolipid 0
                                            (8Z,11Z,14Z)-icosatrienoyl-containing glycerolipid 0
                                            (9Z)-octadec-9-en-12-ynoyl-containing glycerolipid 0
                                            (9Z,11E,13E)-octadecatrienoyl-containing glycerolipid 0
                                            (9Z,11E,13E,15Z)-octadecatetraenoyl-containing glycerolipid 0
                                            (9Z,11E,13Z)-octadeca-9,11,13-trienoyl-containing glycerolipid 0
                                            (9Z,12E)-hexadecadienoyl-containing glycerolipid 0
                                            (9Z,12E)-octadecadienoyl-containing glycerolipid 0
                                            (9Z,12Z)-octadeca-9,12-dien-6-ynoyl-containing glycerolipid 0
                                            (9Z,12Z,15Z)-octadeca-9,12,15-trien-6-ynoyl-containing glycerolipid 0
                                            1(3)-O-(alk-1-enyl)-glycerol + 0
                                            1,2,3-Tris(1-ethoxyethoxy)propane 0
                                            1,2-di-O-stearoyl-3-S-\{2-[(2-\{beta-D-Glcp-(1->4)-[beta-D-Glcp-(1->4)-beta-D-Glcp-(1->6)]-beta-D-GlcpNAc-1-O-yl\}ethyl)amino]-2-oxoethyl\}monothioglycerol 0
                                            1,2-diacyl-sn-glycerolipid + 0
                                            1-(1,2-saturated-acyl)-2-acyl-sn-glycerolipid + 0
                                            1-O-(alk-1-enyl)-2-acyl-sn-glycerolipid + 0
                                            1-[(6Z,9Z,12Z,15Z)-octadec-6,9,12,15-tetraenoyl]-2-acylglycerolipid 0
                                            1-acyl-2-[(3E)-hexadec-3-enoyl]-glycerolipid 0
                                            1-acyl-2-[(7Z)-hexadec-7-enoyl]-glycerolipid 0
                                            1-acyl-2-alkylglycerol + 0
                                            1-acyl-2-palmitoleoylglycerolipid 0
                                            1-acyl-2-palmitoylglycerolipid 0
                                            1-alkenyl-2-acylglycerol 0
                                            1-alkyl-2-acetylglycerol + 0
                                            1-alkyl-2-acylglycerol + 0
                                            1-linoleoyl-2-acylglycerolipid 0
                                            1-oleoyl-2-acylglycerolipid 0
                                            1-radyl-2-acyl-sn-glycerolipid + 0
                                            1-stearoyl 2-acylglycerolipid 0
                                            alk-1-enylacylglycerol + 0
                                            alkyldiacylglycerol + 0
                                            alpha-linolenoyl-containing glycerolipid + 0
                                            arachidonoyl-containing glycerolipid 0
                                            dihexosyldiradylglycerol + 0
                                            diradylglycerol + 24
                                            gamma-linolenoyl-containing glycerolipid + 0
                                            glyceride + 104
                                            glycerophospholipid + 209
                                            glycerophosphonolipid + 0
                                            glycosyldiradylglycerol + 0
                                            glycosylmonoradylglycerol + 0
                                            linoleoyl-containing glycerolipid 0
                                            monoalkyldiacylglycerol + 0
                                            monohexosyldiradylglycerol + 0
                                            monoradylglycerol + 53
                                            monothioglycerolipid + 0
                                            oleoyl-containing glycerolipid 0
                                            omega-3-arachidonoyl-containing glycerolipid 0
                                            palmitoleoyl-containing glycerolipid 0
                                            triradylglycerol + 40
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