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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:Toll-like receptor signaling pathway
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Accession:PW:0000814 term browser browse the term
Definition:Toll-like receptors represent a large and the better understood family of pattern recognition receptors that sense an array of exogenous structures, and recent evidence shows they can also recognize defective endogenous molecules. The intracellular signaling cascades they set in motion lead to the expression of inflammatory mediators.
Synonyms:related_synonym: TLR signaling pathway;   Toll-Like Receptors Cascades
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Toll-like receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 IEA KEGG hsa:04620 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G AKT2 AKT serine/threonine kinase 2 IEA KEGG hsa:04620 NCBI chr19:40,230,317...40,285,345
Ensembl chr19:40,230,317...40,285,536 		JBrowse link
G AKT3 AKT serine/threonine kinase 3 IEA KEGG hsa:04620 NCBI chr 1:243,488,233...243,851,079
Ensembl chr 1:243,488,233...243,851,079 		JBrowse link
G CASP8 caspase 8 IEA KEGG hsa:04620 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 IEA KEGG hsa:04620 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCL4 C-C motif chemokine ligand 4 IEA KEGG hsa:04620 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 IEA KEGG hsa:04620 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CD14 CD14 molecule IEA
TAS		 KEGG
RGD		 PMID:22119168 hsa:04620, RGD:7247704 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CD40 CD40 molecule IEA KEGG hsa:04620 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD80 CD80 molecule IEA KEGG hsa:04620 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614 		JBrowse link
G CD86 CD86 molecule IEA KEGG hsa:04620 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex IEA KEGG hsa:04620 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G CTSK cathepsin K IEA KEGG hsa:04620 NCBI chr 1:150,796,208...150,808,260
Ensembl chr 1:150,794,880...150,809,577 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 IEA KEGG hsa:04620 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL11 C-X-C motif chemokine ligand 11 IEA KEGG hsa:04620 NCBI chr 4:76,033,682...76,036,070
Ensembl chr 4:76,033,682...76,041,415 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 IEA KEGG hsa:04620 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 IEA KEGG hsa:04620 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509 		JBrowse link
G FADD Fas associated via death domain IEA KEGG hsa:04620 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit IEA KEGG hsa:04620 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G IFNA1 interferon alpha 1 IEA KEGG hsa:04620 NCBI chr 9:21,440,439...21,441,316
Ensembl chr 9:21,440,439...21,441,316 		JBrowse link
G IFNA10 interferon alpha 10 IEA KEGG hsa:04620 NCBI chr 9:21,206,181...21,207,143
Ensembl chr 9:21,206,181...21,207,143 		JBrowse link
G IFNA13 interferon alpha 13 IEA KEGG hsa:04620 NCBI chr 9:21,367,372...21,368,057
Ensembl chr 9:21,367,372...21,368,057 		JBrowse link
G IFNA14 interferon alpha 14 IEA KEGG hsa:04620 NCBI chr 9:21,239,002...21,240,005
Ensembl chr 9:21,239,002...21,240,005 		JBrowse link
G IFNA16 interferon alpha 16 IEA KEGG hsa:04620 NCBI chr 9:21,216,373...21,217,311
Ensembl chr 9:21,216,373...21,217,311 		JBrowse link
G IFNA17 interferon alpha 17 IEA KEGG hsa:04620 NCBI chr 9:21,227,243...21,228,222
Ensembl chr 9:21,227,243...21,228,222 		JBrowse link
G IFNA2 interferon alpha 2 IEA KEGG hsa:04620 NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398 		JBrowse link
G IFNA21 interferon alpha 21 IEA KEGG hsa:04620 NCBI chr 9:21,165,637...21,166,660
Ensembl chr 9:21,165,637...21,166,660 		JBrowse link
G IFNA4 interferon alpha 4 IEA KEGG hsa:04620 NCBI chr 9:21,186,618...21,187,587
Ensembl chr 9:21,186,618...21,187,587 		JBrowse link
G IFNA5 interferon alpha 5 IEA KEGG hsa:04620 NCBI chr 9:21,304,326...21,305,313
Ensembl chr 9:21,304,326...21,305,313 		JBrowse link
G IFNA6 interferon alpha 6 IEA KEGG hsa:04620 NCBI chr 9:21,350,318...21,350,887
Ensembl chr 9:21,350,253...21,350,956 		JBrowse link
G IFNA7 interferon alpha 7 IEA KEGG hsa:04620 NCBI chr 9:21,201,469...21,202,205
Ensembl chr 9:21,201,469...21,202,205 		JBrowse link
G IFNA8 interferon alpha 8 IEA KEGG hsa:04620 NCBI chr 9:21,409,117...21,410,185
Ensembl chr 9:21,409,117...21,410,185 		JBrowse link
G IFNAR1 interferon alpha and beta receptor subunit 1 IEA KEGG hsa:04620 NCBI chr21:33,324,395...33,359,864
Ensembl chr21:33,324,387...33,359,864 		JBrowse link
G IFNAR2 interferon alpha and beta receptor subunit 2 IEA KEGG hsa:04620 NCBI chr21:33,229,938...33,265,664
Ensembl chr21:33,205,282...33,265,675 		JBrowse link
G IFNB1 interferon beta 1 IEA KEGG hsa:04620 NCBI chr 9:21,077,104...21,077,942
Ensembl chr 9:21,077,104...21,077,942 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta IEA KEGG hsa:04620 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon IEA KEGG hsa:04620 NCBI chr 1:206,470,476...206,496,889
Ensembl chr 1:206,470,476...206,496,889 		JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma IEA KEGG hsa:04620 NCBI chr  X:154,541,238...154,565,046
Ensembl chr  X:154,541,199...154,565,046 		JBrowse link
G IL12A interleukin 12A IEA KEGG hsa:04620 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019 		JBrowse link
G IL12B interleukin 12B IEA KEGG hsa:04620 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL1B interleukin 1 beta IEA KEGG hsa:04620 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 IEA KEGG hsa:04620 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 TAS
IEA		 KEGG
RGD		 PMID:21235323 hsa:04620, RGD:5685014 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,506...154,019,902 		JBrowse link
G IRAK2 interleukin 1 receptor associated kinase 2 TAS RGD PMID:21235323 RGD:5685014 NCBI chr 3:10,164,919...10,243,745
Ensembl chr 3:10,164,919...10,243,745 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 ISO RGD PMID:28954388 RGD:34888230 NCBI chr12:66,189,214...66,254,622
Ensembl chr12:66,189,195...66,254,622 		JBrowse link
G IRAK4 interleukin 1 receptor associated kinase 4 TAS
IEA		 KEGG
RGD		 PMID:21235323 hsa:04620, RGD:5685014 NCBI chr12:43,758,951...43,789,541
Ensembl chr12:43,758,944...43,798,307 		JBrowse link
G IRF3 interferon regulatory factor 3 TAS
IEA		 KEGG
RGD		 PMID:21235323 hsa:04620, RGD:5685014 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875 		JBrowse link
G IRF5 interferon regulatory factor 5 IEA KEGG hsa:04620 NCBI chr 7:128,937,032...128,950,038
Ensembl chr 7:128,937,457...128,950,038 		JBrowse link
G IRF7 interferon regulatory factor 7 IEA KEGG hsa:04620 NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit IEA KEGG hsa:04620 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G LBP lipopolysaccharide binding protein IEA
TAS		 KEGG
RGD		 PMID:22119168 hsa:04620, RGD:7247704 NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013 		JBrowse link
G LY96 lymphocyte antigen 96 TAS
IEA		 KEGG
RGD		 PMID:21741580 PMID:22119168 hsa:04620, RGD:5685019, RGD:7247704 NCBI chr 8:73,991,392...74,099,857
Ensembl chr 8:73,991,392...74,029,079 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 IEA KEGG hsa:04620 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 IEA KEGG hsa:04620 NCBI chr19:4,090,321...4,124,122
Ensembl chr19:4,090,321...4,124,122 		JBrowse link
G MAP2K3 mitogen-activated protein kinase kinase 3 IEA KEGG hsa:04620 NCBI chr17:21,284,711...21,315,240
Ensembl chr17:21,284,672...21,315,232 		JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 IEA KEGG hsa:04620 NCBI chr17:12,020,877...12,143,828
Ensembl chr17:12,020,829...12,143,830 		JBrowse link
G MAP2K6 mitogen-activated protein kinase kinase 6 IEA KEGG hsa:04620 NCBI chr17:69,414,697...69,553,865
Ensembl chr17:69,414,697...69,553,865 		JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 IEA KEGG hsa:04620 NCBI chr19:7,903,877...7,914,478
Ensembl chr19:7,903,843...7,914,478 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 TAS
IEA		 KEGG
RGD		 PMID:21235323 hsa:04620, RGD:5685014 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MAP3K8 mitogen-activated protein kinase kinase kinase 8 IEA KEGG hsa:04620 NCBI chr10:30,434,021...30,461,833
Ensembl chr10:30,434,021...30,461,833 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 IEA KEGG hsa:04620 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK10 mitogen-activated protein kinase 10 IEA KEGG hsa:04620 NCBI chr 4:86,010,405...86,594,074
Ensembl chr 4:85,990,007...86,594,625 		JBrowse link
G MAPK11 mitogen-activated protein kinase 11 IEA KEGG hsa:04620 NCBI chr22:50,263,713...50,270,380
Ensembl chr22:50,263,713...50,270,767 		JBrowse link
G MAPK12 mitogen-activated protein kinase 12 IEA KEGG hsa:04620 NCBI chr22:50,252,901...50,261,683
Ensembl chr22:50,245,450...50,261,716 		JBrowse link
G MAPK13 mitogen-activated protein kinase 13 IEA KEGG hsa:04620 NCBI chr 6:36,130,513...36,144,521
Ensembl chr 6:36,127,809...36,144,524 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 IEA KEGG hsa:04620 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 IEA KEGG hsa:04620 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 IEA KEGG hsa:04620 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 IEA KEGG hsa:04620 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor TAS
IEA		 KEGG
RGD		 PMID:21235323 hsa:04620, RGD:5685014 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 IEA KEGG hsa:04620 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NFKBIA NFKB inhibitor alpha IEA KEGG hsa:04620 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IEA KEGG hsa:04620 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta IEA KEGG hsa:04620 NCBI chr 3:138,652,698...138,834,928
Ensembl chr 3:138,652,698...138,834,928 		JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta IEA KEGG hsa:04620 NCBI chr 1:9,627,258...9,729,114
Ensembl chr 1:9,629,889...9,729,114 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma IEA KEGG hsa:04620 NCBI chr 7:106,865,282...106,908,980
Ensembl chr 7:106,865,278...106,908,980 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 IEA KEGG hsa:04620 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 IEA KEGG hsa:04620 NCBI chr19:18,153,163...18,170,532
Ensembl chr19:18,153,163...18,170,532 		JBrowse link
G PIK3R3 phosphoinositide-3-kinase regulatory subunit 3 IEA KEGG hsa:04620 NCBI chr 1:46,040,140...46,174,901
Ensembl chr 1:46,040,140...46,133,036 		JBrowse link
G PIK3R5 phosphoinositide-3-kinase regulatory subunit 5 IEA KEGG hsa:04620 NCBI chr17:8,878,916...8,965,707
Ensembl chr17:8,878,911...8,965,712 		JBrowse link
G RAC1 Rac family small GTPase 1 IEA KEGG hsa:04620 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit IEA KEGG hsa:04620 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 TAS
IEA		 KEGG
RGD		 PMID:21235323 hsa:04620, RGD:5685014 NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187 		JBrowse link
G SPP1 secreted phosphoprotein 1 IEA KEGG hsa:04620 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 IEA KEGG hsa:04620 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 TAS
IEA		 KEGG
RGD		 PMID:20940366 hsa:04620, RGD:5685016 NCBI chr22:39,399,780...39,437,132
Ensembl chr22:39,399,778...39,437,060 		JBrowse link
G TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 TAS
IEA		 KEGG
RGD		 PMID:20940366 hsa:04620, RGD:5685016 NCBI chr 6:149,217,926...149,411,607
Ensembl chr 6:149,218,641...149,411,613 		JBrowse link
G TAB3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TAS RGD PMID:20940366 RGD:5685016 NCBI chr  X:30,827,442...30,889,254
Ensembl chr  X:30,827,442...30,975,084 		JBrowse link
G TBK1 TANK binding kinase 1 TAS
IEA		 KEGG
RGD		 PMID:21235323 hsa:04620, RGD:5685014 NCBI chr12:64,452,120...64,502,114
Ensembl chr12:64,452,090...64,502,114 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 TAS
IEA		 KEGG
RGD		 PMID:21235323 hsa:04620, RGD:5685014 NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 TAS
IEA		 KEGG
RGD		 PMID:21235323 hsa:04620, RGD:5685014 NCBI chr 5:115,578,496...115,602,479
Ensembl chr 5:115,578,496...115,602,479 		JBrowse link
G TIRAP TIR domain containing adaptor protein TAS
IEA		 KEGG
RGD		 PMID:21235323 hsa:04620, RGD:5685014 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TLR1 toll like receptor 1 ISO
IEA
TAS		 KEGG
RGD		 PMID:16973131 PMID:21235323 hsa:04620, RGD:1643119, RGD:5685014 NCBI chr 4:38,787,569...38,805,644
Ensembl chr 4:38,790,677...38,856,817 		JBrowse link
G TLR2 toll like receptor 2 ISO
IEA
TAS		 KEGG
RGD		 PMID:16973131 PMID:18353287 PMID:21235323 hsa:04620, RGD:1643119, RGD:5684896, RGD:5685014 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TLR3 toll like receptor 3 ISO
IEA
TAS		 KEGG
RGD		 PMID:16973131 PMID:21235323 hsa:04620, RGD:1643119, RGD:5685014 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073 		JBrowse link
G TLR4 toll like receptor 4 ISO
TAS
IEA		 KEGG
RGD		 PMID:16973131 PMID:22119168 PMID:21235323 hsa:04620, RGD:1643119, RGD:7247704, RGD:5685014 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR5 toll like receptor 5 ISO
IEA
TAS		 KEGG
RGD		 PMID:16973131 PMID:21235323 hsa:04620, RGD:1643119, RGD:5685014 NCBI chr 1:223,109,404...223,143,248
Ensembl chr 1:223,109,404...223,143,292 		JBrowse link
G TLR6 toll like receptor 6 ISO
IEA
TAS		 KEGG
RGD		 PMID:16973131 PMID:21235323 PMID:18353287 hsa:04620, RGD:1643119, RGD:5685014, RGD:5684896 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
G TLR7 toll like receptor 7 TAS
IEA		 KEGG
RGD		 PMID:21235323 hsa:04620, RGD:5685014 NCBI chr  X:12,867,072...12,890,361
Ensembl chr  X:12,867,072...12,890,361 		JBrowse link
G TLR8 toll like receptor 8 TAS
IEA		 KEGG
RGD		 PMID:21235323 hsa:04620, RGD:5685014 NCBI chr  X:12,906,620...12,923,169
Ensembl chr  X:12,906,620...12,923,169 		JBrowse link
G TLR9 toll like receptor 9 ISO
IEA
TAS		 KEGG
RGD		 PMID:16973131 PMID:21235323 hsa:04620, RGD:1643119, RGD:5685014 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TNF tumor necrosis factor IEA KEGG hsa:04620 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TOLLIP toll interacting protein IEA KEGG hsa:04620 NCBI chr11:1,274,371...1,309,632
Ensembl chr11:1,274,371...1,309,654 		JBrowse link
G TRADD TNFRSF1A associated via death domain TAS RGD PMID:21235323 RGD:5685014 NCBI chr16:67,154,185...67,159,909
Ensembl chr16:67,154,185...67,159,909 		JBrowse link
G TRAF3 TNF receptor associated factor 3 TAS
IEA		 KEGG
RGD		 PMID:21235323 hsa:04620, RGD:5685014 NCBI chr14:102,777,449...102,911,500
Ensembl chr14:102,777,449...102,911,500 		JBrowse link
G TRAF6 TNF receptor associated factor 6 TAS
IEA		 KEGG
RGD		 PMID:21235323 hsa:04620, RGD:5685014 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G UBE2N ubiquitin conjugating enzyme E2 N TAS RGD PMID:21235323 RGD:5685014 NCBI chr12:93,405,684...93,441,947
Ensembl chr12:93,405,673...93,441,947 		JBrowse link
G UBE2V1 ubiquitin conjugating enzyme E2 V1 TAS RGD PMID:21235323 RGD:5685014 NCBI chr20:50,081,124...50,115,957
Ensembl chr20:50,081,124...50,115,959 		JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator TAS RGD PMID:21235323 RGD:5685014 NCBI chr11:67,991,100...68,004,097
Ensembl chr11:67,991,100...68,004,982 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5958
    signaling pathway 2506
      signaling pathway pertinent to immunity 606
        signaling pathway in the innate immune response 169
          pattern recognition receptor mediated signaling pathway 168
            Toll-like receptor signaling pathway 109
              Toll-like receptor 1 signaling pathway 0
              Toll-like receptor 10 signaling pathway 0
              Toll-like receptor 2 signaling pathway 0
              Toll-like receptor 3 signaling pathway 0
              Toll-like receptor 4 signaling pathway 0
              Toll-like receptor 5 signaling pathway 0
              Toll-like receptor 6 signaling pathway 0
              Toll-like receptor 7 signaling pathway 0
              Toll-like receptor 8 signaling pathway 0
              Toll-like receptor 9 signaling pathway 0
              Toll-like receptor TLR1:TLR2 signaling pathway 0
              Toll-like receptor TLR6:TLR2 signaling pathway 0
Path 2
Term Annotations click to browse term
  pathway 5958
    regulatory pathway 3604
      immune response pathway 486
        innate immune response pathway 318
          inflammatory response pathway 251
            pattern recognition receptor mediated signaling pathway 168
              Toll-like receptor signaling pathway 109
                Toll-like receptor 1 signaling pathway 0
                Toll-like receptor 10 signaling pathway 0
                Toll-like receptor 2 signaling pathway 0
                Toll-like receptor 3 signaling pathway 0
                Toll-like receptor 4 signaling pathway 0
                Toll-like receptor 5 signaling pathway 0
                Toll-like receptor 6 signaling pathway 0
                Toll-like receptor 7 signaling pathway 0
                Toll-like receptor 8 signaling pathway 0
                Toll-like receptor 9 signaling pathway 0
                Toll-like receptor TLR1:TLR2 signaling pathway 0
                Toll-like receptor TLR6:TLR2 signaling pathway 0
paths to the root