Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
C-type lectin receptor signaling pathway 
NOD-like receptor signaling pathway  
Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway  
Toll-like receptor signaling pathway +    
Toll-like receptors represent a large and the better understood family of pattern recognition receptors that sense an array of exogenous structures, and recent evidence shows they can also recognize defective endogenous molecules. The intracellular signaling cascades they set in motion lead to the expression of inflammatory mediators.

View Interactive Diagram

Synonyms
Related Synonyms: TLR signaling pathway ;   Toll-Like Receptors Cascades
Definition Sources: GO:0002224, KEGG:04620, PMID:20303867, PMID:20303872, Reactome:R-HSA-168898

paths to the root