The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
lactacystin inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein] lactacystin affects the localization of AHR protein lactacystin inhibits the reaction [geldanamycin results in increased degradation of AHR protein]; lactacystin inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein]
lactacystin results in increased localization of AIFM1 protein ATRN protein affects the reaction [lactacystin affects the localization of AIFM1 protein]; U 0126 inhibits the reaction [lactacystin results in increased localization of AIFM1 protein]
acetylleucyl-leucyl-norleucinal inhibits the reaction [lactacystin results in decreased expression of and results in decreased secretion of APOB protein]; HSPA5 promotes the reaction [lactacystin results in increased expression of APOB protein]; HSPA5 promotes the reaction [lactacystin results in increased secretion of APOB protein]; lactacystin inhibits the reaction [HSPA5 results in increased degradation of APOB protein]; lactacystin results in increased expression of and results in increased secretion of APOB protein
ATRN protein affects the reaction [lactacystin affects the localization of AIFM1 protein] ATRN protein results in decreased susceptibility to lactacystin
lactacystin results in decreased expression of BCL2 protein lactacystin inhibits the reaction [[pirinixic acid results in increased expression of UCP2 protein] which results in increased degradation of BCL2 protein]; Sirolimus inhibits the reaction [lactacystin results in decreased expression of BCL2 protein] lactacystin inhibits the reaction [sodium bichromate results in decreased expression of BCL2 protein]
lactacystin results in increased activity of CASP3 protein [lactacystin results in increased activity of CASP3 protein] which results in increased cleavage of SPTAN1 protein; calpeptin inhibits the reaction [[lactacystin results in increased activity of CASP3 protein] which results in increased cleavage of SPTAN1 protein] lactacystin results in increased expression of CASP3 protein modified form
lactacystin inhibits the reaction [[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]]
lactacystin inhibits the reaction [[cobaltiprotoporphyrin binds to HPX protein] which results in increased degradation of CCS protein]; lactacystin inhibits the reaction [[Heme binds to HPX protein] which results in increased degradation of CCS protein] lactacystin inhibits the reaction [[Copper Sulfate co-treated with 2,3,2-tetramine] results in increased degradation of CCS protein]
lactacystin results in increased expression of CDKN1B protein lactacystin inhibits the reaction [Estradiol results in increased degradation of CDKN1B protein]
lactacystin inhibits the reaction [Indomethacin results in decreased expression of CTNNB1 protein]; lactacystin inhibits the reaction [resveratrol results in increased degradation of CTNNB1 protein]
lactacystin inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; lactacystin inhibits the reaction [Phenobarbital results in increased expression of CYP2B6 mRNA]
lactacystin inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 mRNA]; lactacystin inhibits the reaction [Phenobarbital results in increased expression of CYP3A4 mRNA]
lactacystin inhibits the reaction [Cycloheximide results in decreased activity of DIO2 protein]; lactacystin inhibits the reaction [Thyroxine results in decreased activity of DIO2 protein]; lactacystin results in increased expression of and results in increased activity of DIO2 protein
lactacystin promotes the reaction [manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; lactacystin promotes the reaction [manganese chloride results in increased expression of HMOX1 protein] lactacystin results in increased expression of HMOX1 mRNA
lactacystin inhibits the reaction [[cobaltiprotoporphyrin binds to HPX protein] which results in increased degradation of CCS protein]; lactacystin inhibits the reaction [[Heme binds to HPX protein] which results in increased degradation of CCS protein]
HSPA5 promotes the reaction [lactacystin results in increased expression of APOB protein]; HSPA5 promotes the reaction [lactacystin results in increased secretion of APOB protein]; lactacystin inhibits the reaction [HSPA5 results in increased degradation of APOB protein]
lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA] lactacystin inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; lactacystin promotes the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]
lactacystin inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; lactacystin promotes the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]
lactacystin results in increased expression of IL6 mRNA; lactacystin results in increased expression of IL6 protein Quercetin inhibits the reaction [lactacystin results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [lactacystin results in increased expression of IL6 protein]
lactacystin results in increased expression of NFE2L2 protein lactacystin promotes the reaction [manganese chloride affects the localization of and results in increased activity of NFE2L2 protein]; lactacystin promotes the reaction [manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]] lactacystin promotes the reaction [Cadmium Chloride results in increased expression of NFE2L2 protein] lactacystin results in decreased degradation of NFE2L2 protein
lactacystin inhibits the reaction [GW 7647 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; lactacystin inhibits the reaction [pirinixic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; lactacystin inhibits the reaction [zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; lactacystin inhibits the reaction [zinc protoporphyrin inhibits the reaction [lipoteichoic acid results in increased expression of NOS2 protein]]; lactacystin inhibits the reaction [zinc protoporphyrin inhibits the reaction [Peptidoglycan results in increased expression of NOS2 protein]] lactacystin inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; lactacystin inhibits the reaction [deoxynivalenol results in increased degradation of NOS2 protein]; lactacystin promotes the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]
lactacystin results in increased expression of OPTN protein lactacystin results in increased expression of and results in increased ubiquitination of OPTN protein
lactacystin inhibits the reaction [Estradiol results in increased expression of SKP2 protein] lactacystin results in decreased expression of SKP2 protein
lactacystin promotes the reaction [SNCA protein mutant form binds to SNCA protein mutant form] lactacystin results in decreased expression of SNCA protein
lactacystin inhibits the reaction [Glucose deficiency results in increased degradation of SOD1 protein] Copper promotes the reaction [lactacystin affects the localization of SOD1 protein mutant form]; Ditiocarb inhibits the reaction [lactacystin affects the localization of SOD1 protein mutant form]
[lactacystin results in increased activity of CASP3 protein] which results in increased cleavage of SPTAN1 protein; calpain inhibitor III inhibits the reaction [lactacystin results in increased cleavage of SPTAN1 protein]; calpeptin inhibits the reaction [[lactacystin results in increased activity of CASP3 protein] which results in increased cleavage of SPTAN1 protein]; calpeptin inhibits the reaction [lactacystin results in increased cleavage of SPTAN1 protein]
lactacystin inhibits the reaction [[Cisplatin results in increased phosphorylation of TP63 protein alternative form] which results in increased degradation of STK11 protein]
lactacystin inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; lactacystin inhibits the reaction [TNF protein results in increased expression of COMT protein]; lactacystin promotes the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein] lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF mRNA]; lactacystin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
lactacystin inhibits the reaction [Acetaminophen results in increased degradation of TP53 protein]; lactacystin results in increased phosphorylation of and results in increased expression of TP53 protein lactacystin results in increased ubiquitination of TP53 protein
lactacystin inhibits the reaction [[Cisplatin results in increased phosphorylation of TP63 protein alternative form] which results in increased degradation of STK11 protein]; lactacystin inhibits the reaction [[Cisplatin results in increased phosphorylation of TP63 protein alternative form] which results in increased degradation of TP63 protein alternative form]
lactacystin inhibits the reaction [[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]]
lactacystin inhibits the reaction [[pirinixic acid results in increased expression of UCP2 protein] which results in increased degradation of BCL2 protein]
lactacystin promotes the reaction [VCP protein binds to UBXN1 protein binds to PSMD4 protein] lactacystin results in increased expression of VCP protein
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