GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfe2l2 | decreases degradation | EXP | | 6480464 | CTD | lactacystin results in decreased degradation of NFE2L2 protein | PMID:26598004 | Nfe2l2 | multiple interactions | EXP | | 6480464 | CTD | lactacystin promotes the reaction [manganese chloride affects the localization of and results in increased activity of NFE2L2 protein]; lactacystin promotes the reaction [manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]] | PMID:21384399 | Nfe2l2 | increases expression | ISO | NFE2L2 (Homo sapiens) | 6480464 | CTD | lactacystin results in increased expression of NFE2L2 protein | PMID:12446695 | Nfe2l2 | increases expression | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | lactacystin results in increased expression of NFE2L2 protein | PMID:12441344 PMID:15322212 | Nfe2l2 | multiple interactions | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | lactacystin promotes the reaction [Cadmium Chloride results in increased expression of NFE2L2 protein] | PMID:12441344 | |
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