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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:1,2-dichlorobenzene
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Accession:CHEBI:35290 term browser browse the term
Definition:A dichlorobenzene carrying chloro substituents at positions 1 and 2.
Synonyms:related_synonym: 1,2-dichlorbenzene;   2-dichlorobenzene;   Formula=C6H4Cl2;   InChI=1S/C6H4Cl2/c7-5-3-1-2-4-6(5)8/h1-4H;   InChIKey=RFFLAFLAYFXFSW-UHFFFAOYSA-N;   ODB;   ODCB;   SMILES=Clc1ccccc1Cl;   o-Dichlorobenzene;   o-dichlorbenzene;   o-dichlorbenzol;   o-dichlorobenzol;   ortho-dichlorobenzene;   orthodichlorobenzol
 alt_id: CHEBI:32498;   CHEBI:34045
 xref: Beilstein:606078;   CAS:95-50-1;   Gmelin:82493;   KEGG:C14328
 xref_mesh: MESH:C004726
 xref: MetaCyc:O-DICHLOROBENZENE;   PDBeChem:YAN;   PMID:10048141;   PMID:10698672;   PMID:14168435;   PMID:15792297;   PMID:22165224;   Reaxys:606078;   Wikipedia:1\,2-Dichlorobenzene


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1,2-dichlorobenzene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase multiple interactions EXP CAT protein inhibits the reaction [[2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP2D2 protein] CTD PMID:24713513 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression EXP 2-dichlorobenzene results in increased expression of CXCL1 protein CTD PMID:12915711 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases oxidation
multiple interactions		 ISO
EXP		 CYP1A1 protein results in increased oxidation of 2-dichlorobenzene
[2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP1A1 protein		 CTD PMID:7747284 PMID:24713513 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases oxidation ISO CYP1A2 protein results in increased oxidation of 2-dichlorobenzene CTD PMID:7747284 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 multiple interactions EXP [2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP2D2 protein; CAT protein inhibits the reaction [[2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP2D2 protein] CTD PMID:24713513 NCBI chr 7:113,935,138...113,939,209
Ensembl chr 7:113,935,138...113,939,209 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases oxidation
increases metabolic processing
multiple interactions		 ISO
EXP		 CYP2E1 protein results in increased oxidation of 2-dichlorobenzene
CYP2E1 protein results in increased metabolism of 2-dichlorobenzene
[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene; dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene]
[2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP2E1 protein; [Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene; dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene]		 CTD PMID:7747284 PMID:9817075 PMID:24713513 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 multiple interactions EXP [2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP3A62 protein CTD PMID:24713513 NCBI chr12:16,397,998...16,433,833
Ensembl chr12:16,397,998...16,433,833 		JBrowse link
G Glud1 glutamate dehydrogenase 1 increases activity
multiple interactions		 EXP
ISO		 2-dichlorobenzene results in increased activity of GLUD1 protein
cyclohexanone promotes the reaction [2-dichlorobenzene results in increased activity of GLUD1 protein]; methyl isobutyl ketone promotes the reaction [2-dichlorobenzene results in increased activity of GLUD1 protein]; methylethyl ketone promotes the reaction [2-dichlorobenzene results in increased activity of GLUD1 protein]		 CTD PMID:2554539 PMID:3012827 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity EXP 2-dichlorobenzene results in increased activity of GPT protein CTD PMID:8440869 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects localization
decreases activity		 ISO 2-dichlorobenzene affects the localization of GSTP1 protein
2-dichlorobenzene results in decreased activity of GSTP1 protein		 CTD PMID:18409811 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hras HRas proto-oncogene, GTPase increases expression EXP 2-dichlorobenzene results in increased expression of HRAS mRNA CTD PMID:10614693 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases activity
increases phosphorylation		 EXP 2-dichlorobenzene results in increased activity of JUN protein
2-dichlorobenzene results in increased phosphorylation of JUN protein		 CTD PMID:12915711 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression EXP 2-dichlorobenzene results in increased expression of MYC mRNA CTD PMID:10614693 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nefh neurofilament heavy chain affects expression EXP 2-dichlorobenzene affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351 		JBrowse link
G Pcna proliferating cell nuclear antigen increases expression EXP 2-dichlorobenzene results in increased expression of PCNA protein CTD PMID:9184194 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Sord sorbitol dehydrogenase increases activity EXP 2-dichlorobenzene results in increased activity of SORD protein CTD PMID:3012827 NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO 2-dichlorobenzene results in increased expression of TNF protein CTD PMID:9574806 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
3,4-dichloroaniline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acss2 acyl-CoA synthetase short-chain family member 2 decreases expression EXP 3,4-dichloroaniline results in decreased expression of ACSS2 mRNA CTD PMID:24172598 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675 		JBrowse link
G Acvr1c activin A receptor type 1C increases expression ISO 3,4-dichloroaniline results in increased expression of ACVR1C mRNA CTD PMID:24172598 NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327 		JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 increases expression ISO 3,4-dichloroaniline results in increased expression of ADAMTS9 mRNA CTD PMID:24172598 NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929 		JBrowse link
G Ajuba ajuba LIM protein decreases expression ISO 3,4-dichloroaniline results in decreased expression of AJUBA mRNA CTD PMID:24172598 NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 increases expression ISO 3,4-dichloroaniline results in increased expression of AKR1C1 mRNA CTD PMID:24172598 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO 3,4-dichloroaniline results in increased expression of AKR1C2 mRNA CTD PMID:24172598 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression ISO 3,4-dichloroaniline results in increased expression of AKR1C3 mRNA CTD PMID:24172598 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression EXP 3,4-dichloroaniline results in increased expression of ALDH1A3 mRNA CTD PMID:24172598 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436 		JBrowse link
G Anln anillin, actin binding protein decreases expression ISO 3,4-dichloroaniline results in decreased expression of ANLN mRNA CTD PMID:24172598 NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538 		JBrowse link
G Anp32e acidic nuclear phosphoprotein 32 family member E decreases expression ISO 3,4-dichloroaniline results in decreased expression of ANP32E mRNA CTD PMID:24172598 NCBI chr 2:183,472,600...183,489,057
Ensembl chr 2:183,472,609...183,489,054 		JBrowse link
G Antxr2 ANTXR cell adhesion molecule 2 increases expression ISO 3,4-dichloroaniline results in increased expression of ANTXR2 mRNA CTD PMID:24172598 NCBI chr14:11,541,718...11,682,110
Ensembl chr14:11,541,772...11,682,094 		JBrowse link
G Aox1 aldehyde oxidase 1 decreases expression ISO 3,4-dichloroaniline results in decreased expression of AOX1 mRNA CTD PMID:24172598 NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770 		JBrowse link
G Ass1 argininosuccinate synthase 1 increases expression EXP 3,4-dichloroaniline results in increased expression of ASS1 mRNA CTD PMID:24172598 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO 3,4-dichloroaniline results in increased expression of ATF3 mRNA CTD PMID:24172598 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 increases expression ISO 3,4-dichloroaniline results in increased expression of ATP6V0D2 mRNA CTD PMID:24172598 NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354 		JBrowse link
G Axl Axl receptor tyrosine kinase decreases expression ISO 3,4-dichloroaniline results in decreased expression of AXL mRNA CTD PMID:24172598 NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265 		JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO 3,4-dichloroaniline results in increased expression of BMP6 mRNA CTD PMID:24172598 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G C3 complement C3 increases expression ISO
EXP		 3,4-dichloroaniline results in increased expression of C3 mRNA CTD PMID:24172598 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C5h1orf210 similar to human chromosome 1 open reading frame 210 increases expression ISO 3,4-dichloroaniline results in increased expression of C1ORF210 mRNA CTD PMID:24172598 NCBI chr 5:132,048,755...132,051,913
Ensembl chr 5:132,048,773...132,051,925 		JBrowse link
G Ccdc113 coiled-coil domain containing 113 decreases expression ISO 3,4-dichloroaniline results in decreased expression of CFAP263 mRNA CTD PMID:24172598 NCBI chr19:9,497,000...9,516,917
Ensembl chr19:9,496,886...9,516,923 		JBrowse link
G Ccn1 cellular communication network factor 1 decreases expression ISO 3,4-dichloroaniline results in decreased expression of CCN1 mRNA CTD PMID:24172598 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO 3,4-dichloroaniline results in decreased expression of CCN2 mRNA CTD PMID:24172598 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Cdcp1 CUB domain containing protein 1 increases expression ISO 3,4-dichloroaniline results in increased expression of CDCP1 mRNA CTD PMID:24172598 NCBI chr 8:122,828,685...122,865,345
Ensembl chr 8:122,828,685...122,865,388 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 increases expression ISO 3,4-dichloroaniline results in increased expression of CEACAM1 mRNA CTD PMID:24172598 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Cep126 centrosomal protein 126 decreases expression ISO 3,4-dichloroaniline results in decreased expression of CEP126 mRNA CTD PMID:24172598 NCBI chr 8:5,200,576...5,267,740
Ensembl chr 8:5,218,509...5,267,467 		JBrowse link
G Cfap20dc CFAP20 domain containing increases expression ISO 3,4-dichloroaniline results in increased expression of CFAP20DC mRNA CTD PMID:24172598 NCBI chr15:16,231,248...16,476,978
Ensembl chr15:16,231,299...16,476,977 		JBrowse link
G Cfap300 cilia and flagella associated protein 300 decreases expression ISO 3,4-dichloroaniline results in decreased expression of CFAP300 mRNA CTD PMID:24172598 NCBI chr 8:5,180,180...5,198,840
Ensembl chr 8:5,180,675...5,198,807 		JBrowse link
G Cldn11 claudin 11 decreases expression ISO 3,4-dichloroaniline results in decreased expression of CLDN11 mRNA CTD PMID:24172598 NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050 		JBrowse link
G Clgn calmegin increases expression ISO 3,4-dichloroaniline results in increased expression of CLGN mRNA CTD PMID:24172598 NCBI chr19:24,695,140...24,728,542
Ensembl chr19:24,696,875...24,728,758 		JBrowse link
G Cndp1 carnosine dipeptidase 1 increases expression EXP 3,4-dichloroaniline results in increased expression of CNDP1 mRNA CTD PMID:24172598 NCBI chr18:77,984,886...78,030,837
Ensembl chr18:77,984,907...78,007,765 		JBrowse link
G Col8a1 collagen type VIII alpha 1 chain decreases expression ISO 3,4-dichloroaniline results in decreased expression of COL8A1 mRNA CTD PMID:24172598 NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424 		JBrowse link
G Cstb cystatin B increases expression ISO 3,4-dichloroaniline results in increased expression of CSTB mRNA CTD PMID:24172598 NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526 		JBrowse link
G Ctse cathepsin E increases expression EXP 3,4-dichloroaniline results in increased expression of CTSE mRNA CTD PMID:24172598 NCBI chr13:43,091,954...43,114,509
Ensembl chr13:43,092,128...43,114,502 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression EXP 3,4-dichloroaniline results in increased expression of CX3CL1 mRNA CTD PMID:24172598 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO 3,4-dichloroaniline results in decreased expression of CYP17A1 mRNA CTD PMID:31100596 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression ISO 3,4-dichloroaniline results in increased expression of CYP19A1 mRNA CTD PMID:31100596 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO 3,4-dichloroaniline results in increased expression of CYP1A1 mRNA; 3,4-dichloroaniline results in increased expression of CYP1A1 protein CTD PMID:21784029 PMID:24172598 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO 3,4-dichloroaniline results in increased expression of CYP1A2 mRNA; 3,4-dichloroaniline results in increased expression of CYP1A2 protein CTD PMID:21784029 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO 3,4-dichloroaniline results in increased expression of CYP1B1 mRNA CTD PMID:24172598 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 increases expression ISO 3,4-dichloroaniline results in increased expression of CYP4F3 mRNA CTD PMID:24172598 NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO 3,4-dichloroaniline results in increased expression of DNAJB9 mRNA CTD PMID:24172598 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063 		JBrowse link
G Dner delta/notch-like EGF repeat containing increases expression ISO 3,4-dichloroaniline results in increased expression of DNER mRNA CTD PMID:24172598 NCBI chr 9:85,586,985...85,902,461
Ensembl chr 9:85,586,987...85,902,637 		JBrowse link
G Dpp4 dipeptidylpeptidase 4 increases expression ISO 3,4-dichloroaniline results in increased expression of DPP4 mRNA CTD PMID:24172598 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901 		JBrowse link
G Dst dystonin decreases expression ISO 3,4-dichloroaniline results in decreased expression of DST mRNA CTD PMID:24172598 NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615 		JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 decreases expression ISO 3,4-dichloroaniline results in decreased expression of EFEMP1 mRNA CTD PMID:24172598 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018 		JBrowse link
G Egr1 early growth response 1 decreases expression EXP 3,4-dichloroaniline results in decreased expression of EGR1 mRNA CTD PMID:24172598 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 decreases expression EXP 3,4-dichloroaniline results in decreased expression of ELOVL6 mRNA CTD PMID:24172598 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186 		JBrowse link
G Eno2 enolase 2 increases expression ISO 3,4-dichloroaniline results in increased expression of ENO2 mRNA CTD PMID:24172598 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980 		JBrowse link
G Entpd3 ectonucleoside triphosphate diphosphohydrolase 3 increases expression ISO 3,4-dichloroaniline results in increased expression of ENTPD3 mRNA CTD PMID:24172598 NCBI chr 8:120,246,412...120,277,943
Ensembl chr 8:120,247,121...120,277,943 		JBrowse link
G Erp27 endoplasmic reticulum protein 27 decreases expression ISO 3,4-dichloroaniline results in decreased expression of ERP27 mRNA CTD PMID:24172598 NCBI chr 4:169,804,656...169,821,660
Ensembl chr 4:169,804,658...169,821,660 		JBrowse link
G Fgfbp1 fibroblast growth factor binding protein 1 decreases expression EXP 3,4-dichloroaniline results in decreased expression of FGFBP1 mRNA CTD PMID:24172598 NCBI chr14:67,103,686...67,107,492
Ensembl chr14:67,104,545...67,107,496 		JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B decreases expression ISO 3,4-dichloroaniline results in decreased expression of FKBP1B mRNA CTD PMID:24172598 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653 		JBrowse link
G Fstl1 follistatin-like 1 decreases expression ISO 3,4-dichloroaniline results in decreased expression of FSTL1 mRNA CTD PMID:24172598 NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677 		JBrowse link
G Fyb1 FYN binding protein 1 increases expression ISO 3,4-dichloroaniline results in increased expression of FYB1 mRNA CTD PMID:24172598 NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629 		JBrowse link
G Gask1b golgi associated kinase 1B decreases expression ISO 3,4-dichloroaniline results in decreased expression of GASK1B mRNA CTD PMID:24172598 NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression EXP 3,4-dichloroaniline results in increased expression of GDF15 mRNA CTD PMID:24172598 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gjb6 gap junction protein, beta 6 decreases expression ISO 3,4-dichloroaniline results in decreased expression of GJB6 mRNA CTD PMID:24172598 NCBI chr15:31,284,561...31,294,552
Ensembl chr15:31,284,419...31,294,582 		JBrowse link
G Has2 hyaluronan synthase 2 increases expression ISO 3,4-dichloroaniline results in increased expression of HAS2 mRNA CTD PMID:24172598 NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933 		JBrowse link
G Hist1h2al1 histone cluster 1 H2A family like 1 increases expression ISO 3,4-dichloroaniline results in increased expression of H2AC6 mRNA CTD PMID:24172598 NCBI chr17:42,707,954...42,708,420 JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase increases expression ISO 3,4-dichloroaniline results in increased expression of HPGD mRNA CTD PMID:24172598 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228 		JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 increases expression ISO 3,4-dichloroaniline results in increased expression of HSD17B2 mRNA CTD PMID:24172598 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202 		JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 decreases expression EXP 3,4-dichloroaniline results in decreased expression of HSD17B7 mRNA CTD PMID:24172598 NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017 		JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 increases expression ISO 3,4-dichloroaniline results in increased expression of HSPA6 mRNA CTD PMID:24172598 NCBI chr13:83,273,176...83,274,317 JBrowse link
G Id3 inhibitor of DNA binding 3 decreases expression ISO 3,4-dichloroaniline results in decreased expression of ID3 mRNA CTD PMID:24172598 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression EXP 3,4-dichloroaniline results in decreased expression of IDI1 mRNA CTD PMID:24172598 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357 		JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 increases expression EXP 3,4-dichloroaniline results in increased expression of IFITM3 mRNA CTD PMID:24172598 NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression ISO 3,4-dichloroaniline results in increased expression of IGFBP3 mRNA CTD PMID:24172598 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 decreases expression EXP 3,4-dichloroaniline results in decreased expression of IGFBP6 mRNA CTD PMID:24172598 NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression ISO 3,4-dichloroaniline results in increased expression of IL1RL1 mRNA CTD PMID:24172598 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256 		JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression ISO 3,4-dichloroaniline results in increased expression of IL1RN mRNA CTD PMID:24172598 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Itga1 integrin subunit alpha 1 increases expression EXP 3,4-dichloroaniline results in increased expression of ITGA1 mRNA CTD PMID:24172598 NCBI chr 2:46,646,125...46,812,237
Ensembl chr 2:46,653,193...46,812,238 		JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 decreases expression ISO 3,4-dichloroaniline results in decreased expression of KCNJ2 mRNA CTD PMID:24172598 NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445 		JBrowse link
G Kif20a kinesin family member 20A decreases expression ISO 3,4-dichloroaniline results in decreased expression of KIF20A mRNA CTD PMID:24172598 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780 		JBrowse link
G Klhl13 kelch-like family member 13 decreases expression ISO 3,4-dichloroaniline results in decreased expression of KLHL13 mRNA CTD PMID:24172598 NCBI chr  X:113,942,309...114,107,299
Ensembl chr  X:113,942,309...114,107,321 		JBrowse link
G Klhl24 kelch-like family member 24 increases expression EXP 3,4-dichloroaniline results in increased expression of KLHL24 mRNA CTD PMID:24172598 NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636 		JBrowse link
G Klrc3 killer cell lectin like receptor C3 decreases expression ISO 3,4-dichloroaniline results in decreased expression of KLRC3 mRNA CTD PMID:24172598 NCBI chr 4:163,105,081...163,112,737
Ensembl chr 4:163,106,024...163,112,336 		JBrowse link
G Klrg2 killer cell lectin like receptor G2 decreases expression ISO 3,4-dichloroaniline results in decreased expression of KLRG2 mRNA CTD PMID:24172598 NCBI chr 4:67,360,216...67,374,867
Ensembl chr 4:67,363,919...67,374,147 		JBrowse link
G Knl1 kinetochore scaffold 1 decreases expression ISO 3,4-dichloroaniline results in decreased expression of KNL1 mRNA CTD PMID:24172598 NCBI chr 3:106,029,627...106,091,915
Ensembl chr 3:106,029,661...106,091,915 		JBrowse link
G Krt34 keratin 34 increases expression ISO 3,4-dichloroaniline results in increased expression of KRT34 mRNA CTD PMID:24172598 NCBI chr10:84,969,988...84,974,098
Ensembl chr10:84,970,017...84,974,040 		JBrowse link
G Lamb3 laminin subunit beta 3 increases expression ISO 3,4-dichloroaniline results in increased expression of LAMB3 mRNA CTD PMID:24172598 NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405 		JBrowse link
G Lcn2 lipocalin 2 increases expression ISO
EXP		 3,4-dichloroaniline results in increased expression of LCN2 mRNA CTD PMID:24172598 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Maf MAF bZIP transcription factor increases expression ISO 3,4-dichloroaniline results in increased expression of MAF mRNA CTD PMID:24172598 NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365 		JBrowse link
G Matn3 matrilin 3 decreases expression ISO 3,4-dichloroaniline results in decreased expression of MATN3 mRNA CTD PMID:24172598 NCBI chr 6:31,748,517...31,768,564
Ensembl chr 6:31,748,474...31,768,101 		JBrowse link
G Mctp1 multiple C2 and transmembrane domain containing 1 increases expression ISO 3,4-dichloroaniline results in increased expression of MCTP1 mRNA CTD PMID:24172598 NCBI chr 2:6,071,408...6,761,833
Ensembl chr 2:6,065,808...6,761,833 		JBrowse link
G Mex3b mex-3 RNA binding family member B increases expression EXP 3,4-dichloroaniline results in increased expression of MEX3B mRNA CTD PMID:24172598 NCBI chr 1:136,855,130...136,859,365
Ensembl chr 1:136,855,130...136,859,354 		JBrowse link
G Mical2 microtubule associated monooxygenase, calponin and LIM domain containing 2 increases expression ISO 3,4-dichloroaniline results in increased expression of MICAL2 mRNA CTD PMID:24172598 NCBI chr 1:166,345,853...166,530,575
Ensembl chr 1:166,345,859...166,471,719
Ensembl chr 1:166,345,859...166,471,719 		JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO 3,4-dichloroaniline results in increased expression of MMP1 mRNA CTD PMID:24172598 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp10 matrix metallopeptidase 10 increases expression ISO 3,4-dichloroaniline results in increased expression of MMP10 mRNA CTD PMID:24172598 NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748 		JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression EXP 3,4-dichloroaniline results in increased expression of MMP13 mRNA CTD PMID:24172598 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression EXP 3,4-dichloroaniline results in increased expression of MMP3 mRNA CTD PMID:24172598 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO [[MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 3,4-dichloroaniline] which results in increased expression of MPO protein modified form; [MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 3,4-dichloroaniline CTD PMID:20199096 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Msrb3 methionine sulfoxide reductase B3 decreases expression ISO 3,4-dichloroaniline results in decreased expression of MSRB3 mRNA CTD PMID:24172598 NCBI chr 7:56,260,985...56,426,004
Ensembl chr 7:56,303,308...56,425,496 		JBrowse link
G Muc1 mucin 1, cell surface associated increases expression ISO 3,4-dichloroaniline results in increased expression of MUC1 mRNA CTD PMID:24172598 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Muc16 mucin 16, cell surface associated increases expression ISO 3,4-dichloroaniline results in increased expression of MUC16 mRNA CTD PMID:24172598 NCBI chr 8:16,164,531...16,323,126 JBrowse link
G Myo10 myosin X increases expression ISO 3,4-dichloroaniline results in increased expression of MYO10 mRNA CTD PMID:24172598 NCBI chr 2:76,100,989...76,305,619
Ensembl chr 2:76,100,987...76,303,030 		JBrowse link
G Nat2 N-acetyltransferase 2 increases acetylation ISO NAT2 protein results in increased acetylation of 3,4-dichloroaniline CTD PMID:15627487 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression ISO 3,4-dichloroaniline results in increased expression of NDRG1 mRNA CTD PMID:24172598 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880 		JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 decreases expression
increases expression		 ISO
EXP		 3,4-dichloroaniline results in decreased expression of NEDD9 mRNA
3,4-dichloroaniline results in increased expression of NEDD9 mRNA		 CTD PMID:24172598 NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019 		JBrowse link
G Nt5e 5' nucleotidase, ecto increases expression ISO 3,4-dichloroaniline results in increased expression of NT5E mRNA CTD PMID:24172598 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881 		JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 decreases expression ISO 3,4-dichloroaniline results in decreased expression of NUSAP1 mRNA CTD PMID:24172598 NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624 		JBrowse link
G Ostm1 osteoclastogenesis associated transmembrane protein 1 increases expression ISO 3,4-dichloroaniline results in increased expression of OSTM1 mRNA CTD PMID:24172598 NCBI chr20:46,071,657...46,187,049
Ensembl chr20:46,153,075...46,187,023 		JBrowse link
G Pappa pappalysin increases expression ISO 3,4-dichloroaniline results in increased expression of PAPPA mRNA CTD PMID:24172598 NCBI chr 5:78,497,660...78,735,873
Ensembl chr 5:78,498,300...78,730,666 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO 3,4-dichloroaniline results in increased expression of PDK4 mRNA CTD PMID:24172598 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
G Pgbd5 piggyBac transposable element derived 5 increases expression ISO 3,4-dichloroaniline results in increased expression of PGBD5 mRNA CTD PMID:24172598 NCBI chr19:52,336,751...52,401,906
Ensembl chr19:52,336,751...52,402,397 		JBrowse link
G Plaur plasminogen activator, urokinase receptor increases expression ISO 3,4-dichloroaniline results in increased expression of PLAUR mRNA CTD PMID:24172598 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Pld5 phospholipase D family, member 5 increases expression ISO 3,4-dichloroaniline results in increased expression of PLD5 mRNA CTD PMID:24172598 NCBI chr13:87,895,694...88,232,868
Ensembl chr13:87,896,369...88,232,868 		JBrowse link
G Plk2 polo-like kinase 2 decreases expression ISO 3,4-dichloroaniline results in decreased expression of PLK2 mRNA CTD PMID:24172598 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947 		JBrowse link
G Prdm1 PR/SET domain 1 increases expression ISO 3,4-dichloroaniline results in increased expression of PRDM1 mRNA CTD PMID:24172598 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488 		JBrowse link
G Prnp prion protein decreases expression ISO 3,4-dichloroaniline results in decreased expression of PRNP mRNA CTD PMID:24172598 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937 		JBrowse link
G Prss23 serine protease 23 increases expression EXP 3,4-dichloroaniline results in increased expression of PRSS23 mRNA CTD PMID:24172598 NCBI chr 1:143,402,725...143,422,182
Ensembl chr 1:143,401,396...143,422,091 		JBrowse link
G Ptger4 prostaglandin E receptor 4 decreases expression ISO 3,4-dichloroaniline results in decreased expression of PTGER4 mRNA CTD PMID:24172598 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO 3,4-dichloroaniline results in increased expression of PTGS2 mRNA CTD PMID:24172598 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 decreases expression ISO 3,4-dichloroaniline results in decreased expression of PTPRZ1 mRNA CTD PMID:24172598 NCBI chr 4:51,397,316...51,595,220
Ensembl chr 4:51,397,601...51,595,218 		JBrowse link
G Ralbp1 ralA binding protein 1 increases expression ISO 3,4-dichloroaniline results in increased expression of RALBP1 mRNA CTD PMID:24172598 NCBI chr 9:105,456,425...105,493,235
Ensembl chr 9:105,456,425...105,492,707 		JBrowse link
G Rarres1 retinoic acid receptor responder 1 increases expression ISO 3,4-dichloroaniline results in increased expression of RARRES1 mRNA CTD PMID:24172598 NCBI chr 2:151,749,715...151,783,975
Ensembl chr 2:151,749,715...151,783,978 		JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 increases expression ISO 3,4-dichloroaniline results in increased expression of RBCK1 mRNA CTD PMID:24172598 NCBI chr 3:140,789,079...140,806,017
Ensembl chr 3:140,789,080...140,806,005 		JBrowse link
G Rnf128 ring finger protein 128 increases expression EXP 3,4-dichloroaniline results in increased expression of RNF128 mRNA CTD PMID:24172598 NCBI chr  X:103,183,643...103,298,431
Ensembl chr  X:103,183,831...103,298,423 		JBrowse link
G Rora RAR-related orphan receptor A increases expression ISO 3,4-dichloroaniline results in increased expression of RORA mRNA CTD PMID:24172598 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931 		JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO 3,4-dichloroaniline results in increased expression of SCD mRNA CTD PMID:24172598 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Scg5 secretogranin V increases expression ISO 3,4-dichloroaniline results in increased expression of SCG5 mRNA CTD PMID:24172598 NCBI chr 3:100,544,101...100,588,558
Ensembl chr 3:100,544,099...100,588,463 		JBrowse link
G Scrn1 secernin 1 decreases expression EXP 3,4-dichloroaniline results in decreased expression of SCRN1 mRNA CTD PMID:24172598 NCBI chr 4:83,632,125...83,694,225
Ensembl chr 4:83,632,131...83,693,852 		JBrowse link
G Serpinb2 serpin family B member 2 increases expression
decreases expression		 ISO
EXP		 3,4-dichloroaniline results in increased expression of SERPINB2 mRNA
3,4-dichloroaniline results in decreased expression of SERPINB2 mRNA		 CTD PMID:24172598 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408 		JBrowse link
G Slc16a6 solute carrier family 16, member 6 increases expression ISO 3,4-dichloroaniline results in increased expression of SLC16A6 mRNA CTD PMID:24172598 NCBI chr10:94,424,377...94,447,482
Ensembl chr10:94,426,244...94,448,779 		JBrowse link
G Slc1a6 solute carrier family 1 member 6 decreases expression ISO 3,4-dichloroaniline results in decreased expression of SLC1A6 mRNA CTD PMID:24172598 NCBI chr 7:10,841,836...10,870,424
Ensembl chr 7:10,841,837...10,870,449 		JBrowse link
G Slco4a1 solute carrier organic anion transporter family, member 4a1 increases expression ISO 3,4-dichloroaniline results in increased expression of SLCO4A1 mRNA CTD PMID:24172598 NCBI chr 3:167,559,177...167,578,307
Ensembl chr 3:167,559,316...167,578,305 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 increases expression EXP 3,4-dichloroaniline results in increased expression of SMPD3 mRNA CTD PMID:24172598 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Sohlh2 spermatogenesis and oogenesis specific basic helix-loop-helix 2 decreases expression ISO 3,4-dichloroaniline results in decreased expression of SOHLH2 mRNA CTD PMID:24172598 NCBI chr 2:139,362,246...139,384,700
Ensembl chr 2:139,362,246...139,384,699 		JBrowse link
G Sowaha sosondowah ankyrin repeat domain family member A decreases expression ISO 3,4-dichloroaniline results in decreased expression of SOWAHA mRNA CTD PMID:24172598 NCBI chr10:37,641,823...37,645,390
Ensembl chr10:37,643,444...37,645,102 		JBrowse link
G Spc24 SPC24 component of NDC80 kinetochore complex decreases expression ISO 3,4-dichloroaniline results in decreased expression of SPC24 mRNA CTD PMID:24172598 NCBI chr 8:20,300,315...20,305,354
Ensembl chr 8:20,300,319...20,305,310 		JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 increases expression EXP 3,4-dichloroaniline results in increased expression of ST6GAL1 mRNA CTD PMID:24172598 NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression ISO 3,4-dichloroaniline results in decreased expression of STAR mRNA CTD PMID:31100596 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 increases expression EXP 3,4-dichloroaniline results in increased expression of SULT1B1 mRNA CTD PMID:24172598 NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483 		JBrowse link
G Sun3 Sad1 and UNC84 domain containing 3 increases expression ISO 3,4-dichloroaniline results in increased expression of SUN3 mRNA CTD PMID:24172598 NCBI chr14:83,710,136...83,748,982
Ensembl chr14:83,710,140...83,735,830 		JBrowse link
G Taf9b TATA-box binding protein associated factor 9b decreases expression ISO 3,4-dichloroaniline results in decreased expression of TAF9B mRNA CTD PMID:24172598 NCBI chr  X:71,289,290...71,300,142
Ensembl chr  X:71,289,290...71,300,604 		JBrowse link
G Tent5b terminal nucleotidyltransferase 5B decreases expression ISO 3,4-dichloroaniline results in decreased expression of TENT5B mRNA CTD PMID:24172598 NCBI chr 5:145,695,358...145,702,668
Ensembl chr 5:145,695,362...145,706,073 		JBrowse link
G Tgfbi transforming growth factor, beta induced decreases expression EXP 3,4-dichloroaniline results in decreased expression of TGFBI mRNA CTD PMID:24172598 NCBI chr17:7,955,603...7,984,903
Ensembl chr17:7,955,603...7,985,240 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO 3,4-dichloroaniline results in increased expression of TIMP1 mRNA CTD PMID:24172598 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tmcc3 transmembrane and coiled-coil domain family 3 increases expression ISO 3,4-dichloroaniline results in increased expression of TMCC3 mRNA CTD PMID:24172598 NCBI chr 7:28,893,972...29,171,935
Ensembl chr 7:28,893,967...29,171,926 		JBrowse link
G Tmem117 transmembrane protein 117 increases expression ISO 3,4-dichloroaniline results in increased expression of TMEM117 mRNA CTD PMID:24172598 NCBI chr 7:125,757,591...126,219,692
Ensembl chr 7:125,757,591...126,219,690 		JBrowse link
G Tmem154 transmembrane protein 154 increases expression ISO 3,4-dichloroaniline results in increased expression of TMEM154 mRNA CTD PMID:24172598 NCBI chr 2:170,015,247...170,054,903
Ensembl chr 2:170,015,184...170,052,481 		JBrowse link
G Tmem40 transmembrane protein 40 decreases expression ISO 3,4-dichloroaniline results in decreased expression of TMEM40 mRNA CTD PMID:24172598 NCBI chr 4:148,791,509...148,819,287
Ensembl chr 4:148,791,505...148,823,665 		JBrowse link
G Tnfaip8l1 TNF alpha induced protein 8 like 1 decreases expression ISO 3,4-dichloroaniline results in decreased expression of TNFAIP8L1 mRNA CTD PMID:24172598 NCBI chr 9:988,587...999,342
Ensembl chr 9:988,594...1,002,254 		JBrowse link
G Tnfsf13b TNF superfamily member 13b increases expression ISO 3,4-dichloroaniline results in increased expression of TNFSF13B mRNA CTD PMID:24172598 NCBI chr16:79,462,406...79,492,888
Ensembl chr16:79,462,402...79,492,693 		JBrowse link
G Tp63 tumor protein p63 decreases expression EXP 3,4-dichloroaniline results in decreased expression of TP63 mRNA CTD PMID:24172598 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
G Tprg1 tumor protein p63 regulated 1 decreases expression ISO 3,4-dichloroaniline results in decreased expression of TPRG1 mRNA CTD PMID:24172598 NCBI chr11:75,322,470...75,449,907
Ensembl chr11:75,322,470...75,449,907 		JBrowse link
G Trib3 tribbles pseudokinase 3 decreases expression EXP 3,4-dichloroaniline results in decreased expression of TRIB3 mRNA CTD PMID:24172598 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Trim59 tripartite motif-containing 59 decreases expression ISO 3,4-dichloroaniline results in decreased expression of TRIM59 mRNA CTD PMID:24172598 NCBI chr 2:153,269,210...153,281,185
Ensembl chr 2:153,268,584...153,281,031 		JBrowse link
G Trim6 tripartite motif containing 6 decreases expression ISO 3,4-dichloroaniline results in decreased expression of TRIM6 mRNA CTD PMID:24172598 NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914 		JBrowse link
G Ubd ubiquitin D increases expression EXP 3,4-dichloroaniline results in increased expression of UBD mRNA CTD PMID:24172598 NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639 		JBrowse link
G Vgll1 vestigial-like family member 1 decreases expression ISO 3,4-dichloroaniline results in decreased expression of VGLL1 mRNA CTD PMID:24172598 NCBI chr  X:134,979,657...134,996,007 JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 increases expression ISO 3,4-dichloroaniline results in increased expression of ZBTB1 mRNA CTD PMID:24172598 NCBI chr 6:95,096,838...95,125,811
Ensembl chr 6:95,096,387...95,118,996 		JBrowse link
G Zc3h13 zinc finger CCCH type containing 13 decreases expression EXP 3,4-dichloroaniline results in decreased expression of ZC3H13 mRNA CTD PMID:24172598 NCBI chr15:50,607,335...50,671,802
Ensembl chr15:50,607,380...50,671,802 		JBrowse link
G Zfp866 zinc finger protein 866 increases expression EXP 3,4-dichloroaniline results in increased expression of CXCL5 mRNA CTD PMID:24172598 NCBI chr16:19,653,966...19,675,968
Ensembl chr16:19,668,258...19,675,932 		JBrowse link
propanil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO Propanil binds to and results in increased activity of AHR protein CTD PMID:18835618 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ar androgen receptor affects binding
multiple interactions		 EXP
ISO		 Propanil binds to AR protein
Dihydrotestosterone inhibits the reaction [Propanil results in increased activity of AR protein]; Propanil inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]		 CTD PMID:14565775 PMID:15064155 PMID:33049310 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO Propanil results in increased expression of DNAJB1 mRNA CTD PMID:24356939 NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Propanil binds to and results in increased activity of ESR1 protein CTD PMID:33049310 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO Propanil results in decreased expression of HMGCS1 mRNA CTD PMID:24356939 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO Propanil results in increased expression of HSPA1B mRNA CTD PMID:24356939 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO Propanil results in decreased expression of IDI1 mRNA CTD PMID:24356939 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357 		JBrowse link
G Ifng interferon gamma multiple interactions ISO Lipopolysaccharides promotes the reaction [Propanil results in increased expression of IFNG mRNA]; Lipopolysaccharides promotes the reaction [Propanil results in increased expression of IFNG protein] CTD PMID:7679225 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il2 interleukin 2 multiple interactions
decreases stability		 ISO Propanil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Propanil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein]
Propanil results in decreased stability of IL2 mRNA		 CTD PMID:9925799 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il6 interleukin 6 multiple interactions
decreases secretion		 ISO Propanil promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
Propanil inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Propanil inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
Propanil results in decreased secretion of IL6 protein		 CTD PMID:9201266 PMID:9221836 PMID:17585980 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Propanil inhibits the reaction [[NFKB1 protein binds to NFKB1 protein] which binds to TNF promoter]; Propanil inhibits the reaction [[RELA protein binds to NFKB1 protein] which binds to TNF promoter] CTD PMID:11312646 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Propanil inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:17355946 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Propanil binds to and results in increased activity of NR1I2 protein CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO Propanil binds to and results in increased activity of PPARG protein CTD PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Propanil inhibits the reaction [[RELA protein binds to NFKB1 protein] which binds to TNF promoter]; Propanil inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:11312646 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Sqle squalene epoxidase decreases expression ISO Propanil results in decreased expression of SQLE mRNA CTD PMID:24356939 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618 		JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO Propanil binds to and results in increased activity of THRA protein CTD PMID:33049310 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO Propanil binds to and results in increased activity of THRB protein CTD PMID:33049310 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Tnf tumor necrosis factor decreases expression
increases expression
decreases secretion
multiple interactions		 ISO Propanil results in decreased expression of TNF protein
Propanil results in increased expression of TNF protein
Propanil results in decreased secretion of TNF protein
Lipopolysaccharides promotes the reaction [Propanil results in increased expression of TNF protein]; Propanil inhibits the reaction [[NFKB1 protein binds to NFKB1 protein] which binds to TNF promoter]; Propanil inhibits the reaction [[RELA protein binds to NFKB1 protein] which binds to TNF promoter]; Propanil inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Propanil inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]		 CTD PMID:7679225 PMID:9201266 PMID:9221836 PMID:11312646 PMID:17355946 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Zfp628 zinc finger protein 628 decreases expression ISO Propanil results in decreased expression of ZNF628 mRNA CTD PMID:24356939 NCBI chr 1:68,913,600...68,921,186
Ensembl chr 1:68,910,401...68,921,243 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      biological role 19815
        biochemical role 19529
          metabolite 19515
            1,2-dichlorobenzene 186
              3,4-dichloroaniline + 172
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            organic molecule 19686
                              organic cyclic compound 19498
                                carbocyclic compound 18588
                                  benzenoid aromatic compound 18000
                                    benzenes 17862
                                      chlorobenzenes 14839
                                        dichlorobenzene 11537
                                          1,2-dichlorobenzene 186
                                            3,4-dichloroaniline + 172
paths to the root