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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:bifenthrin
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Accession:CHEBI:3093 term browser browse the term
Definition:A carboxylic ester obtained by formal condensation of cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylic acid and [(2-methyl-1,1'-biphenyl)-3-yl]methanol.
Synonyms:exact_synonym: (2-methyl-[1,1'-biphenyl]-3-yl)methyl rel-(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate
 related_synonym: Biphenthrin;   Formula=C23H22ClF3O2;   InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-/t18-,20-/m0/s1;   InChIKey=OMFRMAHOUUJSGP-IRHGGOMRSA-N;   SMILES=Cc1c(COC(=O)[C@@H]2[C@H](\\C=C(/Cl)C(F)(F)F)C2(C)C)cccc1-c1ccccc1
 xref: Beilstein:8512305;   CAS:82657-04-3;   KEGG:C10980
 xref_mesh: MESH:C099952
 xref: PMID:19950221;   PMID:20563640;   PMID:21104824;   PMID:21246035;   PMID:21360666;   PMID:21370390;   PMID:21394881;   PMID:21503692;   PMID:21520766;   PMID:21563678;   PMID:21635642;   PMID:21718662;   PMID:21735922;   PMID:21770011;   PMID:21819079


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bifenthrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, sub-family B member 1B increases expression EXP bifenthrin results in increased expression of ABCB1B mRNA CTD PMID:26071804 NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315 		JBrowse link
G Ache acetylcholinesterase decreases expression
multiple interactions		 ISO bifenthrin results in decreased expression of ACHE mRNA; bifenthrin results in decreased expression of ACHE protein
bifenthrin results in decreased expression of and results in decreased activity of ACHE protein		 CTD PMID:29775722 PMID:30978409 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728 		JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) increases expression EXP bifenthrin results in increased expression of ADH1 mRNA CTD PMID:26071804 NCBI chr 3:137,983,346...137,996,459
Ensembl chr 3:137,966,752...137,996,459 		JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide increases expression EXP bifenthrin results in increased expression of ADH5 mRNA CTD PMID:26071804 NCBI chr 3:138,142,961...138,161,260
Ensembl chr 3:138,148,854...138,161,260 		JBrowse link
G Ahr aryl-hydrocarbon receptor increases expression EXP bifenthrin results in increased expression of AHR mRNA CTD PMID:26071804 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 increases expression EXP bifenthrin results in increased expression of ALDH1A1 mRNA CTD PMID:26071804 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase decreases expression EXP bifenthrin results in decreased expression of ALOX12 mRNA CTD PMID:26071804 NCBI chr11:70,132,283...70,146,206
Ensembl chr11:70,132,283...70,146,179 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase increases expression EXP bifenthrin results in increased expression of ALOX15 mRNA CTD PMID:26071804 NCBI chr11:70,234,973...70,279,465
Ensembl chr11:70,234,978...70,242,857 		JBrowse link
G Alpl alkaline phosphatase, liver/bone/kidney multiple interactions ISO bifenthrin inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression EXP bifenthrin results in increased expression of APAF1 mRNA CTD PMID:26071804 PMID:32408700 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632 		JBrowse link
G Apoe apolipoprotein E increases expression EXP bifenthrin results in increased expression of APOE mRNA CTD PMID:26071804 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Areg amphiregulin multiple interactions ISO bifenthrin inhibits the reaction [CGA protein results in increased expression of AREG mRNA] CTD PMID:21251947 NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression EXP bifenthrin results in increased expression of ARNT mRNA CTD PMID:26071804 NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551 		JBrowse link
G Bax BCL2-associated X protein increases expression EXP bifenthrin results in increased expression of BAX mRNA CTD PMID:32408700 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bche butyrylcholinesterase decreases activity ISO bifenthrin results in decreased activity of BCHE protein CTD PMID:30978409 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression EXP bifenthrin results in decreased expression of BCL2 mRNA CTD PMID:26071804 PMID:27916261 PMID:32408700 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bid BH3 interacting domain death agonist increases expression EXP bifenthrin results in increased expression of BID mRNA CTD PMID:26071804 PMID:32408700 NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814 		JBrowse link
G Brca1 breast cancer 1, early onset affects binding ISO bifenthrin binds to BRCA1 protein CTD PMID:32278787 NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781 		JBrowse link
G Casp3 caspase 3 increases activity
increases expression		 EXP
ISO		 bifenthrin results in increased activity of CASP3 protein
bifenthrin results in increased expression of CASP3 mRNA
bifenthrin results in increased expression of CASP3 protein		 CTD PMID:26071804 PMID:27916261 PMID:30978409 PMID:32408700 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp8 caspase 8 increases activity
decreases expression		 EXP bifenthrin results in increased activity of CASP8 protein
bifenthrin results in decreased expression of CASP8 mRNA		 CTD PMID:26071804 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Casp9 caspase 9 increases expression EXP bifenthrin results in increased expression of CASP9 mRNA CTD PMID:32408700 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Cat catalase multiple interactions
decreases activity
affects activity
increases expression
decreases expression		 ISO
EXP		 Quercetin inhibits the reaction [bifenthrin results in decreased activity of CAT protein]; Rutin inhibits the reaction [bifenthrin results in decreased activity of CAT protein]
bifenthrin affects the activity of CAT protein; bifenthrin analog affects the activity of CAT protein
bifenthrin analog results in increased expression of CAT mRNA; bifenthrin results in increased expression of CAT mRNA
bifenthrin results in decreased expression of CAT protein		 CTD PMID:19833193 PMID:23172818 PMID:25149237 PMID:27916261 PMID:29775722 More... NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Ccne1 cyclin E1 multiple interactions ISO bifenthrin inhibits the reaction [CGA protein results in increased expression of CCNE1 mRNA] CTD PMID:21251947 NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959 		JBrowse link
G Cd36 CD36 molecule increases expression ISO bifenthrin results in increased expression of CD36 mRNA CTD PMID:29554630 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A multiple interactions ISO bifenthrin inhibits the reaction [CGA protein results in increased expression of CDKN1A mRNA] CTD PMID:21251947 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO bifenthrin inhibits the reaction [CGA protein results in increased expression of CEBPB mRNA] CTD PMID:21251947 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338 		JBrowse link
G Ces2a carboxylesterase 2A affects metabolic processing EXP CES2A protein affects the metabolism of bifenthrin CTD PMID:15123619 NCBI chr 8:105,460,635...105,468,266
Ensembl chr 8:105,460,635...105,468,266 		JBrowse link
G Ces2e carboxylesterase 2E affects metabolic processing EXP CES2E protein affects the metabolism of bifenthrin CTD PMID:15123619 NCBI chr 8:105,652,892...105,661,304
Ensembl chr 8:105,652,892...105,661,304 		JBrowse link
G Ces2h carboxylesterase 2H increases metabolic processing ISO CES2 protein results in increased metabolism of bifenthrin CTD PMID:19249324 NCBI chr 8:105,727,462...105,747,042
Ensembl chr 8:105,727,485...105,747,810 		JBrowse link
G Cga glycoprotein hormones, alpha subunit multiple interactions
increases secretion		 ISO bifenthrin analog inhibits the reaction [CGA protein results in increased abundance of Progesterone]; bifenthrin analog inhibits the reaction [CGA protein results in increased secretion of Dinoprostone]; bifenthrin analog inhibits the reaction [CGA results in increased expression of CYP11A1 mRNA]; bifenthrin analog inhibits the reaction [CGA results in increased expression of DBI mRNA]; bifenthrin analog inhibits the reaction [CGA results in increased expression of PTGS2 mRNA]; bifenthrin analog inhibits the reaction [CGA results in increased expression of STAR mRNA]; bifenthrin analog inhibits the reaction [CGA results in increased expression of TSPO mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of AREG mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CCNE1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CDKN1A mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CEBPB mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CYP11A1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CYP19A1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of EREG mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of PGR mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of PTGS2 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of RUNX1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of STAR mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of SULT1E1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of TGFB1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased secretion of Dinoprostone]
bifenthrin results in increased secretion of CGA protein
fulvestrant inhibits the reaction [bifenthrin results in increased secretion of CGA protein]		 CTD PMID:21251947 PMID:21871944 PMID:24938463 NCBI chr 4:34,893,779...34,907,374
Ensembl chr 4:34,893,779...34,907,370 		JBrowse link
G Chat choline O-acetyltransferase decreases expression ISO bifenthrin results in decreased expression of CHAT mRNA CTD PMID:29775722 NCBI chr14:32,130,160...32,187,866
Ensembl chr14:32,130,160...32,187,946 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1, CNS decreases expression ISO bifenthrin results in decreased expression of CHRM1 mRNA CTD PMID:29775722 PMID:30978409 NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951 		JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit decreases expression ISO bifenthrin results in decreased expression of CHRNA2 mRNA CTD PMID:30978409 NCBI chr14:66,370,685...66,390,397
Ensembl chr14:66,372,488...66,390,397 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver decreases expression ISO bifenthrin results in decreased expression of CPT1A mRNA CTD PMID:29554630 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression EXP bifenthrin results in decreased expression of CXCL1 mRNA CTD PMID:28251819 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459 		JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 increases expression EXP bifenthrin results in increased expression of CYB5R3 mRNA CTD PMID:26071804 NCBI chr15:83,037,696...83,060,641
Ensembl chr15:83,037,695...83,056,793 		JBrowse link
G Cycs cytochrome c, somatic increases expression EXP bifenthrin results in increased expression of CYCS mRNA CTD PMID:32408700 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression		 ISO
EXP		 bifenthrin analog inhibits the reaction [CGA results in increased expression of CYP11A1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CYP11A1 mRNA]
bifenthrin results in decreased expression of CYP11A1 mRNA
bifenthrin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 mRNA]		 CTD PMID:21251947 PMID:21871944 PMID:23994515 PMID:24449165 PMID:32408700 More... NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 decreases expression ISO bifenthrin results in decreased expression of CYP11B2 mRNA CTD PMID:34896276 NCBI chr15:74,722,467...74,728,080
Ensembl chr15:74,722,859...74,728,167 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases expression
decreases expression
multiple interactions		 ISO
EXP		 bifenthrin results in increased expression of CYP17A1 mRNA
bifenthrin results in decreased expression of CYP17A1 mRNA
bifenthrin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA]		 CTD PMID:23994515 PMID:24449165 PMID:24938463 PMID:26071804 PMID:32408700 More... NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
increases expression		 ISO bifenthrin inhibits the reaction [CGA protein results in increased expression of CYP19A1 mRNA]
bifenthrin results in increased expression of CYP19A1 mRNA		 CTD PMID:21251947 PMID:24938463 NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
decreases expression		 ISO
EXP		 bifenthrin results in increased activity of CYP1A1 protein
bifenthrin results in decreased expression of CYP1A1 mRNA		 CTD PMID:20009351 PMID:26071804 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 decreases expression
multiple interactions		 ISO bifenthrin results in decreased expression of CYP21A2 mRNA
bifenthrin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP21A2 mRNA]		 CTD PMID:34896276 NCBI chr17:35,020,322...35,023,400
Ensembl chr17:35,020,322...35,023,535 		JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 increases expression EXP bifenthrin results in increased expression of CYP2C29 mRNA CTD PMID:26071804 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP bifenthrin results in increased expression of CYP2E1 mRNA CTD PMID:26071804 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900 		JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 decreases expression EXP bifenthrin results in decreased expression of CYP4B1 mRNA CTD PMID:26071804 NCBI chr 4:115,481,895...115,504,918
Ensembl chr 4:115,481,922...115,504,920 		JBrowse link
G Dbi diazepam binding inhibitor multiple interactions ISO bifenthrin analog inhibits the reaction [CGA results in increased expression of DBI mRNA] CTD PMID:21871944 NCBI chr 1:120,041,010...120,048,826
Ensembl chr 1:120,041,010...120,048,808 		JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal increases expression EXP bifenthrin results in increased expression of EPHX1 mRNA CTD PMID:26071804 NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 affects binding ISO bifenthrin binds to ERBB2 protein CTD PMID:32278787 NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542 		JBrowse link
G Ereg epiregulin multiple interactions ISO bifenthrin inhibits the reaction [CGA protein results in increased expression of EREG mRNA] CTD PMID:21251947 NCBI chr 5:91,222,476...91,241,508
Ensembl chr 5:91,222,481...91,241,505 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) decreases expression
affects binding
multiple interactions		 ISO bifenthrin results in decreased expression of ESR1 mRNA
bifenthrin binds to ESR1 protein
bifenthrin binds to and results in increased activity of ESR1 protein		 CTD PMID:20097460 PMID:32278787 PMID:33049310 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions ISO bifenthrin binds to and results in increased activity of ESR2 protein CTD PMID:33049310 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033 		JBrowse link
G Faim Fas apoptotic inhibitory molecule decreases expression EXP bifenthrin results in decreased expression of FAIM mRNA CTD PMID:26071804 NCBI chr 9:98,868,426...98,884,076
Ensembl chr 9:98,868,426...98,884,074 		JBrowse link
G Fasl Fas ligand decreases expression EXP bifenthrin results in decreased expression of FASL mRNA CTD PMID:26071804 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064 		JBrowse link
G Fasn fatty acid synthase increases expression
decreases expression		 ISO
EXP		 bifenthrin results in increased expression of FASN mRNA
bifenthrin results in decreased expression of FASN mRNA		 CTD PMID:29554630 PMID:32408700 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373 		JBrowse link
G Fbp1 fructose bisphosphatase 1 increases expression EXP bifenthrin results in increased expression of FBP1 mRNA CTD PMID:26071804 NCBI chr13:63,012,567...63,036,112
Ensembl chr13:63,012,567...63,036,096 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 affects binding ISO bifenthrin binds to FGFR2 protein CTD PMID:32278787 NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases expression EXP bifenthrin results in increased expression of GGT1 mRNA CTD PMID:26071804 NCBI chr10:75,396,910...75,422,027
Ensembl chr10:75,397,438...75,422,034 		JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 increases expression ISO bifenthrin results in increased expression of GNRH1 mRNA CTD PMID:24938463 NCBI chr14:67,982,717...67,986,889
Ensembl chr14:67,982,630...67,986,888 		JBrowse link
G Gnrhr gonadotropin releasing hormone receptor increases expression ISO bifenthrin results in increased expression of GNRHR mRNA CTD PMID:24938463 NCBI chr 5:86,328,613...86,345,760
Ensembl chr 5:86,328,613...86,345,760 		JBrowse link
G Gpi1 glucose-6-phosphate isomerase 1 increases expression EXP bifenthrin results in increased expression of GPI1 mRNA CTD PMID:26071804 NCBI chr 7:33,900,752...33,929,761
Ensembl chr 7:33,900,755...33,929,761 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression
decreases expression		 EXP bifenthrin results in increased expression of GPX1 mRNA
bifenthrin results in decreased expression of GPX1 mRNA		 CTD PMID:26071804 PMID:27916261 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542 		JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression
decreases expression		 EXP bifenthrin results in increased expression of GPX2 mRNA
bifenthrin results in decreased expression of GPX2 mRNA		 CTD PMID:26071804 PMID:27916261 NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273 		JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression EXP bifenthrin results in increased expression of GPX3 mRNA CTD PMID:26071804 NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203 		JBrowse link
G Gsta3 glutathione S-transferase, alpha 3 increases expression EXP bifenthrin results in increased expression of GSTA1 mRNA; bifenthrin results in increased expression of GSTA3 mRNA CTD PMID:26071804 PMID:27916261 NCBI chr 1:21,310,837...21,335,885
Ensembl chr 1:21,310,813...21,335,885 		JBrowse link
G Gstm1 glutathione S-transferase, mu 1 increases expression EXP bifenthrin results in increased expression of GSTM1 mRNA CTD PMID:26071804 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289 		JBrowse link
G Gstm2 glutathione S-transferase, mu 2 increases expression EXP bifenthrin results in increased expression of GSTM2 mRNA; bifenthrin results in increased expression of GSTM5 mRNA CTD PMID:26071804 NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769 		JBrowse link
G Gstp1 glutathione S-transferase, pi 1 increases expression EXP bifenthrin results in increased expression of GSTP1 mRNA CTD PMID:26071804 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985 		JBrowse link
G H2-M3 histocompatibility 2, M region locus 3 multiple interactions
increases expression		 ISO Fulvestrant inhibits the reaction [bifenthrin results in increased expression of HLA-G mRNA] CTD PMID:24938463 NCBI chr17:37,581,094...37,585,380
Ensembl chr17:37,581,111...37,585,375 		JBrowse link
G Hk2 hexokinase 2 increases expression EXP bifenthrin results in increased expression of HK2 mRNA CTD PMID:26071804 NCBI chr 6:82,702,004...82,751,437
Ensembl chr 6:82,702,006...82,751,435 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP bifenthrin analog results in increased expression of HMOX1 mRNA; bifenthrin results in increased expression of HMOX1 mRNA CTD PMID:25149237 PMID:27916261 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 decreases expression ISO bifenthrin results in decreased expression of HSD17B1 mRNA CTD PMID:24938463 NCBI chr11:100,968,792...100,972,014
Ensembl chr11:100,969,237...100,971,353 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 decreases expression EXP bifenthrin results in decreased expression of HSD17B3 mRNA CTD PMID:26071804 NCBI chr13:64,206,088...64,237,076
Ensembl chr13:64,206,080...64,237,044 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression EXP bifenthrin results in decreased expression of HSD3B1 mRNA CTD PMID:32408700 NCBI chr 3:98,749,672...98,767,110
Ensembl chr 3:98,759,510...98,767,110 		JBrowse link
G Hspa1a heat shock protein 1A decreases expression ISO bifenthrin results in decreased expression of HSPA1A protein CTD PMID:16271832 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132 		JBrowse link
G Hspa5 heat shock protein 5 increases expression ISO bifenthrin results in increased expression of HSPA5 protein CTD PMID:16271832 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559 		JBrowse link
G Hspa8 heat shock protein 8 decreases expression ISO bifenthrin results in decreased expression of HSPA8 protein CTD PMID:16271832 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383 		JBrowse link
G Hspb2 heat shock protein 2 decreases expression ISO bifenthrin results in decreased expression of HSPB2 protein CTD PMID:16271832 NCBI chr 9:50,662,372...50,663,654
Ensembl chr 9:50,662,378...50,663,654 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
increases expression		 EXP
ISO		 bifenthrin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]
bifenthrin results in decreased expression of IL1B mRNA
bifenthrin results in increased expression of IL1B mRNA		 CTD PMID:27916261 PMID:28251819 PMID:30102949 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il2 interleukin 2 increases expression EXP bifenthrin results in increased expression of IL2 mRNA CTD PMID:23172818 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108 		JBrowse link
G Il4 interleukin 4 increases expression EXP bifenthrin results in increased expression of IL4 mRNA CTD PMID:23172818 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
increases expression		 EXP
ISO		 bifenthrin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]
bifenthrin results in decreased expression of IL6 mRNA
bifenthrin results in increased expression of IL6 protein
bifenthrin results in increased expression of IL6 mRNA		 CTD PMID:27916261 PMID:28251819 PMID:29793499 PMID:30102949 PMID:32061760 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Ldlr low density lipoprotein receptor decreases expression EXP bifenthrin results in decreased expression of LDLR mRNA CTD PMID:24449165 PMID:32408700 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 increases phosphorylation ISO bifenthrin analog results in increased phosphorylation of MAPK1 protein CTD PMID:19442700 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases phosphorylation ISO bifenthrin analog results in increased phosphorylation of MAPK3 protein CTD PMID:19442700 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 decreases expression EXP bifenthrin results in decreased expression of MGST2 mRNA CTD PMID:26071804 NCBI chr 3:51,544,179...51,590,096
Ensembl chr 3:51,567,781...51,590,098 		JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 increases expression EXP bifenthrin results in increased expression of MGST3 mRNA CTD PMID:26071804 NCBI chr 1:167,199,535...167,221,410
Ensembl chr 1:167,199,535...167,221,410 		JBrowse link
G Mir122 microRNA 122 increases expression EXP bifenthrin results in increased expression of MIR122 mRNA CTD PMID:32408700 NCBI chr18:65,381,932...65,381,997
Ensembl chr18:65,381,932...65,381,997 		JBrowse link
G Mir17 microRNA 17 decreases expression EXP bifenthrin results in decreased expression of MIR17 mRNA CTD PMID:32408700 NCBI chr14:115,281,103...115,281,186
Ensembl chr14:115,281,103...115,281,186 		JBrowse link
G Mir34b microRNA 34b decreases expression EXP bifenthrin results in decreased expression of MIR34B mRNA CTD PMID:32408700 NCBI chr 9:51,014,862...51,014,945
Ensembl chr 9:51,014,862...51,014,945 		JBrowse link
G Mir34c microRNA 34c decreases expression EXP bifenthrin results in decreased expression of MIR34C mRNA CTD PMID:32408700 NCBI chr 9:51,014,334...51,014,410
Ensembl chr 9:51,014,334...51,014,410 		JBrowse link
G Mir449a microRNA 449a decreases expression EXP bifenthrin results in decreased expression of MIR449A mRNA CTD PMID:32408700 NCBI chr13:113,174,068...113,174,158
Ensembl chr13:113,174,068...113,174,158 		JBrowse link
G Mir449c microRNA 449c decreases expression EXP bifenthrin results in decreased expression of MIR449C mRNA CTD PMID:32408700 NCBI chr13:113,172,517...113,172,625
Ensembl chr13:113,172,517...113,172,625 		JBrowse link
G Mt2 metallothionein 2 increases expression EXP bifenthrin results in increased expression of MT2 mRNA CTD PMID:26071804 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196 		JBrowse link
G Mt3 metallothionein 3 increases expression EXP bifenthrin results in increased expression of MT3 mRNA CTD PMID:26071804 NCBI chr 8:94,879,235...94,880,776
Ensembl chr 8:94,879,235...94,880,774 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase increases expression EXP bifenthrin results in increased expression of MTHFR mRNA CTD PMID:26071804 NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008 		JBrowse link
G Nat1 N-acetyl transferase 1 increases expression EXP bifenthrin results in increased expression of NAT1 mRNA CTD PMID:26071804 NCBI chr 8:67,943,620...67,945,183
Ensembl chr 8:67,933,573...67,944,756 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 decreases expression
increases expression		 ISO bifenthrin results in decreased expression of NFE2L2 mRNA; bifenthrin results in decreased expression of NFE2L2 protein
bifenthrin results in increased expression of NFE2L2 mRNA; bifenthrin results in increased expression of NFE2L2 protein		 CTD PMID:29775722 PMID:29793499 PMID:30102949 PMID:32061760 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 decreases expression
affects binding		 EXP
ISO		 bifenthrin results in decreased expression of NQO1 mRNA
bifenthrin binds to NQO1 protein		 CTD PMID:27916261 PMID:32278787 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO bifenthrin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
increases expression
affects binding
multiple interactions		 ISO
EXP		 bifenthrin results in increased activity of NR1I2 protein
bifenthrin results in increased expression of NR1I2 mRNA; bifenthrin results in increased expression of NR1I2 protein
bifenthrin binds to NR1I2 protein
bifenthrin binds to and results in increased activity of NR1I2 protein		 CTD PMID:19249324 PMID:29554630 PMID:33049310 NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO bifenthrin inhibits the reaction [Hydrocortisone results in increased activity of NR3C1 protein] CTD PMID:26647222 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions ISO bifenthrin inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]; bifenthrin inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein] CTD PMID:29149346 NCBI chr 8:77,626,422...77,971,641
Ensembl chr 8:77,626,070...77,971,641 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 decreases expression ISO bifenthrin results in decreased expression of NR4A2 mRNA; bifenthrin results in decreased expression of NR4A2 protein CTD PMID:30978409 NCBI chr 2:56,996,845...57,014,152
Ensembl chr 2:56,996,842...57,014,015 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic multiple interactions ISO bifenthrin inhibits the reaction [Hydrocortisone results in increased expression of PCK1 mRNA] CTD PMID:26647222 NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066 		JBrowse link
G Pgr progesterone receptor multiple interactions
increases expression		 ISO bifenthrin inhibits the reaction [CGA protein results in increased expression of PGR mRNA]
bifenthrin results in increased expression of PGR; bifenthrin results in increased expression of PGR mRNA
fulvestrant inhibits the reaction [bifenthrin results in increased expression of PGR mRNA]		 CTD PMID:21251947 PMID:24938463 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612 		JBrowse link
G Pklr pyruvate kinase liver and red blood cell decreases expression EXP bifenthrin results in decreased expression of PKLR mRNA CTD PMID:26071804 NCBI chr 3:89,043,429...89,054,122
Ensembl chr 3:89,043,449...89,054,091 		JBrowse link
G Pkm pyruvate kinase, muscle increases expression EXP bifenthrin results in increased expression of PKM mRNA CTD PMID:26071804 NCBI chr 9:59,563,859...59,586,655
Ensembl chr 9:59,563,651...59,586,658 		JBrowse link
G Pon1 paraoxonase 1 increases expression EXP bifenthrin results in increased expression of PON1 mRNA CTD PMID:26071804 NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946 		JBrowse link
G Pon3 paraoxonase 3 increases expression EXP bifenthrin results in increased expression of PON3 mRNA CTD PMID:26071804 NCBI chr 6:5,216,253...5,256,236
Ensembl chr 6:5,220,852...5,256,286 		JBrowse link
G Ppard peroxisome proliferator activator receptor delta affects binding ISO bifenthrin binds to PPARD protein CTD PMID:32278787 NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma increases expression
multiple interactions		 ISO
EXP		 bifenthrin results in increased expression of PPARG mRNA
bifenthrin binds to and results in increased activity of PPARG protein		 CTD PMID:29554630 PMID:33049310 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Ptges prostaglandin E synthase increases expression ISO bifenthrin results in increased expression of PTGES mRNA; bifenthrin results in increased expression of PTGES protein CTD PMID:29775722 PMID:29793499 PMID:30102949 PMID:32061760 NCBI chr 2:30,779,483...30,793,309
Ensembl chr 2:30,779,483...30,819,875 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression		 ISO bifenthrin analog inhibits the reaction [CGA results in increased expression of PTGS2 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of PTGS2 mRNA]; bifenthrin inhibits the reaction [Colforsin results in increased expression of PTGS2 mRNA]
bifenthrin results in increased expression of PTGS2 mRNA; bifenthrin results in increased expression of PTGS2 protein		 CTD PMID:21251947 PMID:21871944 PMID:29775722 PMID:29793499 PMID:30102949 More... NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) increases expression ISO bifenthrin results in increased expression of RELA mRNA; bifenthrin results in increased expression of RELA protein CTD PMID:29775722 PMID:29793499 PMID:30102949 PMID:32061760 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Rora RAR-related orphan receptor alpha affects binding ISO bifenthrin binds to RORA protein CTD PMID:32278787 NCBI chr 9:68,560,627...69,295,528
Ensembl chr 9:68,561,068...69,295,528 		JBrowse link
G Rorc RAR-related orphan receptor gamma affects binding ISO bifenthrin binds to RORC protein CTD PMID:32278787 NCBI chr 3:94,280,106...94,305,583
Ensembl chr 3:94,280,101...94,305,583 		JBrowse link
G Runx1 runt related transcription factor 1 multiple interactions ISO bifenthrin inhibits the reaction [CGA protein results in increased expression of RUNX1 mRNA] CTD PMID:21251947 NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression EXP bifenthrin results in decreased expression of SCARB1 mRNA CTD PMID:23994515 NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158 		JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 increases expression ISO bifenthrin results in increased expression of SCD mRNA CTD PMID:29554630 NCBI chr19:44,282,115...44,295,303
Ensembl chr19:44,282,113...44,295,303 		JBrowse link
G Scn10a sodium channel, voltage-gated, type X, alpha multiple interactions ISO bifenthrin affects the reaction [SCN10A protein results in increased transport of Sodium] CTD PMID:16051293 NCBI chr 9:119,437,522...119,548,388
Ensembl chr 9:119,437,522...119,548,388 		JBrowse link
G Shbg sex hormone binding globulin affects binding ISO bifenthrin binds to SHBG protein CTD PMID:32278787 NCBI chr11:69,501,108...69,508,852
Ensembl chr11:69,505,630...69,508,731 		JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions
increases expression		 ISO
EXP		 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bifenthrin analog results in increased expression of SOD1 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [bifenthrin analog results in increased expression of SOD1 protein]
bifenthrin analog results in increased expression of SOD1 mRNA; bifenthrin results in increased expression of SOD1 mRNA		 CTD PMID:22718203 PMID:25149237 PMID:27916261 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions
increases expression		 ISO
EXP		 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bifenthrin analog results in increased expression of SOD2 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [bifenthrin analog results in increased expression of SOD2 protein]
bifenthrin results in increased expression of SOD2 mRNA		 CTD PMID:22718203 PMID:27916261 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Src Rous sarcoma oncogene affects binding ISO bifenthrin binds to SRC protein CTD PMID:32278787 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 decreases expression EXP bifenthrin results in decreased expression of SRD5A2 mRNA CTD PMID:26071804 NCBI chr17:74,321,886...74,354,855
Ensembl chr17:74,323,950...74,354,911 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
decreases expression		 ISO
EXP		 bifenthrin analog inhibits the reaction [CGA results in increased expression of STAR mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of STAR mRNA]
bifenthrin results in decreased expression of STAR mRNA
bifenthrin results in decreased expression of STAR mRNA; bifenthrin results in decreased expression of STAR protein
bifenthrin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA]; bifenthrin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR protein]		 CTD PMID:21251947 PMID:21871944 PMID:23994515 PMID:34896276 NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010 		JBrowse link
G Sult1e1 sulfotransferase family 1E, member 1 multiple interactions ISO bifenthrin inhibits the reaction [CGA protein results in increased expression of SULT1E1 mRNA] CTD PMID:21251947 NCBI chr 5:87,723,827...87,739,470
Ensembl chr 5:87,723,828...87,739,453 		JBrowse link
G Tff1 trefoil factor 1 increases expression ISO bifenthrin results in increased expression of TFF1 mRNA CTD PMID:20097460 NCBI chr17:31,380,369...31,384,034
Ensembl chr17:31,380,369...31,384,251 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO bifenthrin inhibits the reaction [CGA protein results in increased expression of TGFB1 mRNA] CTD PMID:21251947 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tnf tumor necrosis factor increases expression
decreases expression
multiple interactions		 EXP
ISO		 bifenthrin results in increased expression of TNF mRNA
bifenthrin results in decreased expression of TNF mRNA
bifenthrin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]
bifenthrin results in increased expression of TNF mRNA; bifenthrin results in increased expression of TNF protein		 CTD PMID:23172818 PMID:26071804 PMID:27916261 PMID:28251819 PMID:29775722 More... NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Trp53 transformation related protein 53 increases expression
decreases expression		 EXP bifenthrin results in increased expression of TRP53 mRNA
bifenthrin results in decreased expression of TRP53 mRNA		 CTD PMID:20097460 PMID:26071804 PMID:27916261 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Tspo translocator protein multiple interactions
decreases expression		 ISO
EXP		 bifenthrin analog inhibits the reaction [CGA results in increased expression of TSPO mRNA]
bifenthrin results in decreased expression of TSPO mRNA		 CTD PMID:21871944 PMID:23994515 PMID:24449165 NCBI chr15:83,447,774...83,458,404
Ensembl chr15:83,447,793...83,458,404 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22182
    role 22167
      application 21752
        pesticide 18831
          acaricide 13890
            pyrethroid ester acaricide 3325
              bifenthrin 133
Path 2
Term Annotations click to browse term
  CHEBI ontology 22182
    subatomic particle 22174
      composite particle 22174
        hadron 22174
          baryon 22174
            nucleon 22174
              atomic nucleus 22174
                atom 22174
                  main group element atom 22108
                    p-block element atom 22108
                      carbon group element atom 21909
                        carbon atom 21835
                          organic molecular entity 21835
                            heteroorganic entity 21490
                              organochalcogen compound 20980
                                organooxygen compound 20821
                                  carbon oxoacid 19614
                                    carboxylic acid 19610
                                      monocarboxylic acid 18985
                                        cyclopropanecarboxylic acid 2236
                                          chrysanthemic acid 507
                                            cis-chrysanthemic acid 136
                                              bifenthrin 133
paths to the root