(1->4)-beta-D-glucan multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of CHRNA2 mRNA CTD PMID:36331819 (S)-nicotine multiple interactions ISO CHRNA2 (Homo sapiens) 6480464 Nicotine results in increased activity of [CHRNB4 protein binds to CHRNA2 protein] CTD PMID:9454827 (S)-nicotine affects response to substance ISO CHRNA2 (Homo sapiens) 6480464 CHRNA2 gene mutant form affects the susceptibility to Nicotine CTD PMID:19383498 1,1-dimethyl-4-phenylpiperazinium iodide multiple interactions ISO CHRNA2 (Homo sapiens) 6480464 Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA2 protein] CTD PMID:9454827 1,1-dimethyl-4-phenylpiperazinium iodide multiple interactions ISO Chrna2 (Rattus norvegicus) 2303194 1 and 1-dimethyl-4-phenylpiperazinium iodide affects binding competes with [Epibatidine binds to Chrna2 protein] RGD 1-naphthyl isothiocyanate decreases expression ISO Chrna2 (Rattus norvegicus) 6480464 1-Naphthylisothiocyanate results in decreased expression of CHRNA2 mRNA CTD PMID:30723492 17beta-estradiol increases expression ISO Chrna2 (Rattus norvegicus) 6480464 Estradiol results in increased expression of CHRNA2 mRNA CTD PMID:32145629 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO CHRNA2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of CHRNA2 mRNA CTD PMID:21296121 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Chrna2 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of CHRNA2 mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of CHRNA2 mRNA CTD PMID:28922406 3,7-dihydropurine-6-thione decreases expression ISO Chrna2 (Rattus norvegicus) 6480464 Mercaptopurine results in decreased expression of CHRNA2 mRNA CTD PMID:23358152 4,4'-sulfonyldiphenol increases methylation ISO CHRNA2 (Homo sapiens) 6480464 bisphenol S results in increased methylation of CHRNA2 gene CTD PMID:31601247 4-hydroxyphenyl retinamide increases expression EXP 6480464 Fenretinide results in increased expression of CHRNA2 mRNA CTD PMID:28973697 acetamide increases expression ISO Chrna2 (Rattus norvegicus) 6480464 acetamide results in increased expression of CHRNA2 mRNA CTD PMID:31881176 acetylcholine multiple interactions ISO CHRNA2 (Homo sapiens) 6480464 1-Butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]] more ... CTD PMID:11821649 and PMID:9454827 acetylcholine multiple interactions ISO Chrna2 (Rattus norvegicus) 2303194 acetylcholine affects binding competes with [Epibatidine binds to Chrna2 protein] RGD acetylcholine multiple interactions ISO Chrna2 (Rattus norvegicus) 6480464 Acetylcholine binds to and results in increased activity of [CHRNB2 protein binds to CHRNA2 protein] more ... CTD PMID:7808438 acetylcholine affects response to substance ISO CHRNA2 (Homo sapiens) 6480464 CHRNA2 gene mutant form affects the susceptibility to Acetylcholine CTD PMID:19383498 aflatoxin B1 increases methylation ISO CHRNA2 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of CHRNA2 gene CTD PMID:27153756 aldehydo-D-glucose multiple interactions EXP 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CHRNA2 mRNA CTD PMID:37567420 ammonium chloride affects expression ISO Chrna2 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of CHRNA2 mRNA CTD PMID:16483693 Aroclor 1254 increases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of CHRNA2 mRNA CTD PMID:23650126 atrazine increases expression ISO CHRNA2 (Homo sapiens) 6480464 Atrazine results in increased expression of CHRNA2 mRNA CTD PMID:22378314 barium(0) multiple interactions ISO CHRNA2 (Homo sapiens) 6480464 1-Butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]] more ... CTD PMID:11821649 benzo[a]pyrene multiple interactions EXP 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to CHRNA2 promoter] CTD PMID:19654925 benzo[a]pyrene decreases methylation ISO CHRNA2 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of CHRNA2 5' UTR CTD PMID:27901495 benzo[a]pyrene affects methylation ISO CHRNA2 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of CHRNA2 3' UTR and Benzo(a)pyrene affects the methylation of CHRNA2 promoter CTD PMID:27901495 and PMID:30157460 benzo[a]pyrene increases methylation ISO CHRNA2 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of CHRNA2 3' UTR CTD PMID:27901495 benzo[e]pyrene decreases methylation ISO CHRNA2 (Homo sapiens) 6480464 benzo(e)pyrene results in decreased methylation of CHRNA2 3' UTR CTD PMID:30157460 bexarotene increases expression ISO Chrna2 (Rattus norvegicus) 6480464 bexarotene results in increased expression of CHRNA2 mRNA CTD PMID:16648578 and PMID:17630414 bifenthrin decreases expression ISO Chrna2 (Rattus norvegicus) 6480464 bifenthrin results in decreased expression of CHRNA2 mRNA CTD PMID:30978409 bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of CHRNA2 mRNA CTD PMID:19850644 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of CHRNA2 mRNA] CTD PMID:19850644 bisphenol A decreases expression ISO Chrna2 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of CHRNA2 mRNA CTD PMID:25181051 and PMID:34947998 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of CHRNA2 mRNA CTD PMID:32156529 and PMID:33221593 bisphenol A increases expression ISO Chrna2 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of CHRNA2 mRNA CTD PMID:30816183 and PMID:32528016 bisphenol A increases methylation ISO Chrna2 (Rattus norvegicus) 6480464 bisphenol A results in increased methylation of CHRNA2 gene CTD PMID:28505145 butan-1-ol multiple interactions ISO CHRNA2 (Homo sapiens) 6480464 1-Butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]] CTD PMID:11821649 butan-2-ol multiple interactions ISO CHRNA2 (Homo sapiens) 6480464 2-butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]] CTD PMID:11821649 cadmium dichloride increases expression ISO Chrna2 (Rattus norvegicus) 6480464 Cadmium Chloride results in increased expression of CHRNA2 mRNA CTD PMID:33453195 calcitriol increases expression ISO CHRNA2 (Homo sapiens) 6480464 Calcitriol results in increased expression of CHRNA2 mRNA CTD PMID:21592394 calcitriol multiple interactions ISO CHRNA2 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of CHRNA2 mRNA CTD PMID:21592394 cannabidiol multiple interactions EXP 6480464 [lipopolysaccharide and E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of CHRNA2 mRNA CTD PMID:30742662 cannabidiol decreases expression EXP 6480464 Cannabidiol results in decreased expression of CHRNA2 mRNA CTD PMID:30742662 carbachol multiple interactions ISO Chrna2 (Rattus norvegicus) 2303194 carbachol affects binding competes with [Epibatidine binds to Chrna2 protein] RGD carbamazepine affects response to substance ISO CHRNA2 (Homo sapiens) 6480464 CHRNA2 gene mutant form affects the susceptibility to Carbamazepine CTD PMID:19383498 carbon nanotube increases expression EXP 6480464 Nanotubes more ... CTD PMID:25620056 clofibrate increases expression EXP 6480464 Clofibrate results in increased expression of CHRNA2 mRNA CTD PMID:30629241 clofibrate increases expression ISO Chrna2 (Rattus norvegicus) 6480464 Clofibrate results in increased expression of CHRNA2 mRNA CTD PMID:32741897 clofibric acid affects expression ISO Chrna2 (Rattus norvegicus) 6480464 Clofibric Acid affects the expression of CHRNA2 mRNA CTD PMID:17602206 crotyl alcohol multiple interactions ISO CHRNA2 (Homo sapiens) 6480464 crotonyl alcohol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]] CTD PMID:11821649 cytisine multiple interactions ISO CHRNA2 (Homo sapiens) 6480464 cytisine results in increased activity of [CHRNB4 protein binds to CHRNA2 protein] CTD PMID:9454827 cytisine multiple interactions ISO Chrna2 (Rattus norvegicus) 2303195 cytisine affects binding to Chrna2 protein and cytisine inhibits the reaction [epibatidine affects binding to Chrna2 protein] in rat retina RGD D-glucose multiple interactions EXP 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CHRNA2 mRNA CTD PMID:37567420 dextran sulfate multiple interactions EXP 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CHRNA2 mRNA CTD PMID:29950665 diazinon decreases expression ISO Chrna2 (Rattus norvegicus) 6480464 Diazinon results in decreased expression of CHRNA2 mRNA CTD PMID:18812211 diazinon increases expression ISO Chrna2 (Rattus norvegicus) 6480464 Diazinon results in increased expression of CHRNA2 mRNA CTD PMID:17452286 dichloroacetic acid increases expression EXP 6480464 Dichloroacetic Acid results in increased expression of CHRNA2 mRNA CTD PMID:28962523 dieldrin decreases expression ISO Chrna2 (Rattus norvegicus) 6480464 Dieldrin results in decreased expression of CHRNA2 mRNA CTD PMID:18812211 dihydro-beta-erythroidine multiple interactions ISO Chrna2 (Rattus norvegicus) 2303195 dihydro-beta-erythroidine affects binding to Chrna2 protein and dihydro-beta-erythroidine inhibits the reaction [epibatidine affects binding to Chrna2 protein] in rat retina RGD diquat increases expression EXP 6480464 Diquat results in increased expression of CHRNA2 mRNA CTD PMID:36851058 epibatidine affects binding ISO Chrna2 (Rattus norvegicus) 2303194 Epibatidine binds to Chrna2 protein RGD epibatidine affects binding ISO Chrna2 (Rattus norvegicus) 2303195 epibatidine binds to Chrnb4 protein in the retina RGD epibatidine affects binding ISO CHRNA2 (Homo sapiens) 6480464 [CHRNB4 protein binds to CHRNA2 protein] which binds to epibatidine CTD PMID:9454827 epibatidine multiple interactions ISO Chrna2 (Rattus norvegicus) 6480464 epibatidine binds to and results in increased activity of [CHRNA2 protein binds to CHRNB2 protein] and sazetidine-A analog inhibits the reaction [epibatidine binds to and results in increased activity of [CHRNA2 protein binds to CHRNB2 protein]] CTD PMID:21905669 epoxiconazole decreases expression EXP 6480464 epoxiconazole results in decreased expression of CHRNA2 mRNA CTD PMID:35436446 ethanol affects expression EXP 6480464 Ethanol affects the expression of CHRNA2 mRNA CTD PMID:30319688 fenofibrate increases expression ISO Chrna2 (Rattus norvegicus) 6480464 Fenofibrate results in increased expression of CHRNA2 mRNA CTD PMID:32741897 flavonoids increases expression ISO Chrna2 (Rattus norvegicus) 6480464 Flavonoids results in increased expression of CHRNA2 mRNA CTD PMID:18035473 folic acid decreases expression EXP 6480464 Folic Acid results in decreased expression of CHRNA2 mRNA CTD PMID:25629700 fructose multiple interactions EXP 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CHRNA2 mRNA CTD PMID:37567420 glucose multiple interactions EXP 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CHRNA2 mRNA CTD PMID:37567420 glyphosate increases methylation ISO Chrna2 (Rattus norvegicus) 6480464 Glyphosate results in increased methylation of CHRNA2 gene CTD PMID:31011160 isobutanol multiple interactions ISO CHRNA2 (Homo sapiens) 6480464 isobutyl alcohol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]] CTD PMID:11821649 mercaptopurine decreases expression ISO Chrna2 (Rattus norvegicus) 6480464 Mercaptopurine results in decreased expression of CHRNA2 mRNA CTD PMID:23358152 methapyrilene decreases methylation ISO CHRNA2 (Homo sapiens) 6480464 Methapyrilene results in decreased methylation of CHRNA2 3' UTR CTD PMID:30157460 methyllycaconitine multiple interactions ISO Chrna2 (Rattus norvegicus) 2303194 methyllycaconitine affects binding competes with [Epibatidine binds to Chrna2 protein] RGD methylmercury chloride decreases expression EXP 6480464 methylmercuric chloride results in decreased expression of CHRNA2 mRNA CTD PMID:21385734 Muraglitazar increases expression ISO Chrna2 (Rattus norvegicus) 6480464 muraglitazar results in increased expression of CHRNA2 mRNA CTD PMID:21515302 N-nitrosodiethylamine multiple interactions ISO Chrna2 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CHRNA2 mRNA CTD PMID:20360939 nickel atom decreases expression ISO Chrna2 (Rattus norvegicus) 6480464 Nickel results in decreased expression of CHRNA2 mRNA CTD PMID:18812211 nicotine multiple interactions ISO CHRNA2 (Homo sapiens) 6480464 Nicotine results in increased activity of [CHRNB4 protein binds to CHRNA2 protein] CTD PMID:9454827 nicotine multiple interactions ISO Chrna2 (Rattus norvegicus) 2303194 nicotine affects binding competes with [Epibatidine binds to Chrna2 protein] RGD nicotine multiple interactions ISO Chrna2 (Rattus norvegicus) 2303195 nicotine affects binding to Chrna2 protein and nicotine inhibits the reaction [epibatidine affects binding to Chrna2 protein] in rat retina RGD nicotine affects response to substance ISO CHRNA2 (Homo sapiens) 6480464 CHRNA2 gene mutant form affects the susceptibility to Nicotine CTD PMID:19383498 paracetamol decreases expression ISO Chrna2 (Rattus norvegicus) 6480464 Acetaminophen results in decreased expression of CHRNA2 mRNA CTD PMID:33387578 pentan-1-ol multiple interactions ISO CHRNA2 (Homo sapiens) 6480464 n-pentanol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]] CTD PMID:11821649 perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of CHRNA2 mRNA CTD PMID:36331819 perfluorooctanoic acid increases expression ISO Chrna2 (Rattus norvegicus) 6480464 perfluorooctanoic acid results in increased expression of CHRNA2 mRNA CTD PMID:16221955 and PMID:28511854 permethrin increases expression EXP 6480464 Permethrin results in increased expression of CHRNA2 mRNA CTD PMID:30629241 phenethyl caffeate multiple interactions ISO Chrna2 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CHRNA2 mRNA CTD PMID:20360939 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of CHRNA2 mRNA CTD PMID:23091169 pirinixic acid increases expression ISO Chrna2 (Rattus norvegicus) 6480464 pirinixic acid results in increased expression of CHRNA2 mRNA CTD PMID:12832660 more ... pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of CHRNA2 mRNA CTD PMID:17426115 more ... propan-1-ol multiple interactions ISO CHRNA2 (Homo sapiens) 6480464 1-Propanol promotes the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]] CTD PMID:11821649 propan-2-ol multiple interactions ISO CHRNA2 (Homo sapiens) 6480464 2-Propanol promotes the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]] CTD PMID:11821649 purine-6-thiol decreases expression ISO Chrna2 (Rattus norvegicus) 6480464 Mercaptopurine results in decreased expression of CHRNA2 mRNA CTD PMID:23358152 sodium arsenite affects methylation ISO CHRNA2 (Homo sapiens) 6480464 sodium arsenite affects the methylation of CHRNA2 gene CTD PMID:28589171 sodium fluoride decreases expression EXP 6480464 Sodium Fluoride results in decreased expression of CHRNA2 mRNA CTD PMID:27862939 tert-butanol multiple interactions ISO CHRNA2 (Homo sapiens) 6480464 tert-Butyl Alcohol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]] CTD PMID:11821649 Tesaglitazar increases expression ISO Chrna2 (Rattus norvegicus) 6480464 tesaglitazar results in increased expression of CHRNA2 mRNA CTD PMID:21515302 testosterone multiple interactions ISO CHRNA2 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of CHRNA2 mRNA CTD PMID:21592394 testosterone increases expression ISO CHRNA2 (Homo sapiens) 6480464 Testosterone results in increased expression of CHRNA2 mRNA CTD PMID:21592394 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of CHRNA2 mRNA CTD PMID:29264374 titanium dioxide multiple interactions EXP 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CHRNA2 mRNA CTD PMID:29950665 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of CHRNA2 mRNA CTD PMID:25549359 trichloroethene decreases expression ISO Chrna2 (Rattus norvegicus) 6480464 Trichloroethylene results in decreased expression of CHRNA2 mRNA CTD PMID:33387578 troglitazone increases expression EXP 6480464 troglitazone results in increased expression of CHRNA2 mRNA CTD PMID:28973697 troglitazone increases expression ISO Chrna2 (Rattus norvegicus) 6480464 troglitazone results in increased expression of CHRNA2 mRNA CTD PMID:21515302 tubocurarine multiple interactions ISO Chrna2 (Rattus norvegicus) 6480464 Tubocurarine inhibits the reaction [Acetylcholine binds to and results in increased activity of [CHRNB2 protein binds to CHRNA2 protein]] and Tubocurarine promotes the reaction [Acetylcholine binds to and results in increased activity of [CHRNB4 protein binds to CHRNA2 protein]] CTD PMID:7808438 valproic acid increases methylation ISO CHRNA2 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of CHRNA2 gene CTD PMID:29154799 valproic acid decreases expression ISO Chrna2 (Rattus norvegicus) 6480464 Valproic Acid results in decreased expression of CHRNA2 mRNA CTD PMID:35594946
