Adh1 (alcohol dehydrogenase 1 (class I)) - Rat Genome Database

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Gene: Adh1 (alcohol dehydrogenase 1 (class I)) Mus musculus
Analyze
Symbol: Adh1
Name: alcohol dehydrogenase 1 (class I)
RGD ID: 10090
MGI Page MGI
Description: Enables alcohol dehydrogenase (NAD+) activity and identical protein binding activity. Acts upstream of or within several processes, including behavioral response to ethanol; ethanol catabolic process; and retinoid metabolic process. Located in mitochondrion. Is expressed in several structures, including endocrine gland; epidermis; genitourinary system; intestine; and sensory organ. Human ortholog(s) of this gene implicated in alcohol dependence; late onset Parkinson's disease; and pancreatic cancer. Orthologous to human ADH1A (alcohol dehydrogenase 1A (class I), alpha polypeptide); ADH1B (alcohol dehydrogenase 1B (class I), beta polypeptide); and ADH1C (alcohol dehydrogenase 1C (class I), gamma polypeptide).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ADH; Adh-; Adh-1; Adh-1-; Adh-1-t; Adh-1e; Adh-1t; Adh-3e; ADH-A2; ADH-AA; Adh1-; Adh1-e; Adh1-t; Adh1tl; Adh3-e; AI194826; alcohol dehydrogenase 1; alcohol dehydrogenase 1 temporal, liver; alcohol dehydrogenase 1, complex; alcohol dehydrogenase 1, electrophoretic; alcohol dehydrogenase 3, electrophoretic; alcohol dehydrogenase A subunit; class I alcohol dehydrogenase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Pig
Alliance Genes
More Info more info ...
Related Pseudogenes: Adh1-ps   Adh1-ps2  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393137,983,346 - 137,996,459 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3137,966,752 - 137,996,459 (+)EnsemblGRCm39 Ensembl
GRCm383138,277,585 - 138,290,698 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3138,260,991 - 138,290,698 (+)EnsemblGRCm38mm10GRCm38
MGSCv373137,940,609 - 137,953,655 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363138,215,032 - 138,228,078 (+)NCBIMGSCv36mm8
Celera3144,684,702 - 144,697,775 (+)NCBICelera
Cytogenetic Map3G3NCBI
cM Map364.16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
1H-pyrazole  (EXP,ISO)
2,3,7,8-tetrabromodibenzodioxine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2-butoxyethanol  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4'-hydroxyacetophenone  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-propyl-2-thiouracil  (ISO)
acetaldehyde  (EXP,ISO)
acetamide  (ISO)
acetone  (EXP)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
allyl alcohol  (EXP)
alpha-hexachlorocyclohexane  (ISO)
amitrole  (ISO)
Aroclor 1254  (ISO)
atazanavir sulfate  (ISO)
benzalkonium chloride  (EXP)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
bifenthrin  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bosentan  (ISO)
cadmium dichloride  (EXP)
carbon nanotube  (EXP)
carnosic acid  (EXP)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
chlordecone  (EXP)
cimetidine  (ISO)
cisplatin  (ISO)
clofibrate  (EXP,ISO)
clofibric acid  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crotonaldehyde  (ISO)
cyanamide  (EXP)
cyclosporin A  (ISO)
deoxycholic acid  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diallyl disulfide  (EXP)
dibutyl phthalate  (EXP)
diclofenac  (ISO)
diethyl malate  (EXP)
diethylstilbestrol  (EXP,ISO)
dimethylarsinic acid  (ISO)
dioxygen  (ISO)
disulfiram  (ISO)
endosulfan  (ISO)
epoxiconazole  (ISO)
ethanol  (EXP,ISO)
ethylene glycol  (ISO)
fenofibrate  (ISO)
fenthion  (EXP)
fluconazole  (ISO)
fluoranthene  (EXP)
folic acid  (EXP)
fomepizole  (EXP,ISO)
formaldehyde  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
hydrogen peroxide  (EXP)
indometacin  (ISO)
inulin  (EXP)
irinotecan  (ISO)
isoprenaline  (EXP)
ketoconazole  (ISO)
methamphetamine  (EXP)
methanol  (ISO)
methimazole  (ISO)
mifepristone  (ISO)
milrinone  (ISO)
Monobutylphthalate  (EXP)
Muconic dialdehyde  (EXP)
N-acetyl-L-cysteine  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
N-nitrosomorpholine  (ISO)
naphthalene  (ISO)
nefazodone  (ISO)
nickel atom  (EXP)
nitrofen  (ISO)
obeticholic acid  (ISO)
ochratoxin A  (ISO)
oleanolic acid  (ISO)
omeprazole  (ISO)
ouabain  (ISO)
p-toluidine  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (EXP,ISO)
pirinixic acid  (EXP,ISO)
potassium dichromate  (EXP)
pravastatin  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
progesterone  (ISO)
propan-2-ol  (EXP,ISO)
propanal  (ISO)
raloxifene  (ISO)
rifampicin  (ISO)
rotenone  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
senecionine  (EXP)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
streptozocin  (ISO)
sulfadimethoxine  (ISO)
Sunset Yellow FCF  (ISO)
tamoxifen  (EXP)
taraxerone  (EXP)
tartrazine  (ISO)
tauroursodeoxycholic acid  (ISO)
testosterone  (EXP,ISO)
tetrachloroethene  (EXP)
tetrachloromethane  (EXP,ISO)
titanium dioxide  (EXP)
triadimefon  (ISO)
trichloroethene  (EXP,ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
troglitazone  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
zinc atom  (EXP,ISO)
zinc sulfate  (EXP)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IBA,ISO)
mitochondrion  (IDA)
nucleoplasm  (ISO)
plasma membrane  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Impact of alcohol consumption with polymorphisms in alcohol-metabolizing enzymes on pancreatic cancer risk in Japanese. Kanda J, etal., Cancer Sci. 2008 Dec 4.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Interactions of alcohol dehydrogenase to p-hydroxyacetophenone-sepharose and p-acetamidophenol-sepharose. Negoro M and Wakabayashi I, Alcohol Clin Exp Res. 2005 Dec;29(12 Suppl):304S-8S.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Ethanol concentration-dependent alterations in gene expression during acute binge drinking in the HIV-1 transgenic rat. Sarkar S and Chang SL, Alcohol Clin Exp Res. 2013 Jul;37(7):1082-90. doi: 10.1111/acer.12077. Epub 2013 Feb 15.
Additional References at PubMed
PMID:93520   PMID:518534   PMID:1316195   PMID:1450512   PMID:1794058   PMID:2040456   PMID:2474823   PMID:2565740   PMID:2893758   PMID:2902233   PMID:3011597   PMID:3157987  
PMID:3428612   PMID:3996732   PMID:6370228   PMID:6375655   PMID:6756216   PMID:6816803   PMID:7026729   PMID:7738026   PMID:7748347   PMID:7840644   PMID:7937138   PMID:8018987  
PMID:8119157   PMID:8163197   PMID:8486690   PMID:8621625   PMID:8813054   PMID:8889548   PMID:8892527   PMID:8973327   PMID:9002638   PMID:9145544   PMID:9202249   PMID:9241435  
PMID:9507200   PMID:9726281   PMID:9733106   PMID:10349636   PMID:10358022   PMID:10753524   PMID:10880953   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11747070   PMID:11752298  
PMID:11784316   PMID:11836246   PMID:11893554   PMID:11960985   PMID:12027900   PMID:12128098   PMID:12466851   PMID:12477932   PMID:12631290   PMID:12851412   PMID:14681479   PMID:15193143  
PMID:15489334   PMID:15554233   PMID:15670660   PMID:15765518   PMID:16047160   PMID:16121213   PMID:16141072   PMID:16141073   PMID:16459152   PMID:16705022   PMID:16801720   PMID:16971476  
PMID:17257171   PMID:17270348   PMID:17326332   PMID:17332066   PMID:17626619   PMID:18287559   PMID:21267068   PMID:21873635   PMID:22079585   PMID:23375831   PMID:23772048   PMID:24787690  
PMID:26807981   PMID:26835538   PMID:28378742   PMID:29663519   PMID:33586683   PMID:35354963   PMID:36224745   PMID:37953328  


Genomics

Comparative Map Data
Adh1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393137,983,346 - 137,996,459 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3137,966,752 - 137,996,459 (+)EnsemblGRCm39 Ensembl
GRCm383138,277,585 - 138,290,698 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3138,260,991 - 138,290,698 (+)EnsemblGRCm38mm10GRCm38
MGSCv373137,940,609 - 137,953,655 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363138,215,032 - 138,228,078 (+)NCBIMGSCv36mm8
Celera3144,684,702 - 144,697,775 (+)NCBICelera
Cytogenetic Map3G3NCBI
cM Map364.16NCBI
ADH1C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38499,336,497 - 99,352,746 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl499,336,497 - 99,352,746 (-)EnsemblGRCh38hg38GRCh38
GRCh374100,257,654 - 100,273,903 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364100,476,672 - 100,492,940 (-)NCBINCBI36Build 36hg18NCBI36
Build 344100,614,828 - 100,631,081NCBI
Celera497,554,804 - 97,571,075 (-)NCBICelera
Cytogenetic Map4q23NCBI
HuRef495,995,418 - 96,011,667 (-)NCBIHuRef
CHM1_14100,234,034 - 100,250,392 (-)NCBICHM1_1
T2T-CHM13v2.04102,651,250 - 102,667,501 (-)NCBIT2T-CHM13v2.0
Adh1c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82229,470,703 - 229,482,291 (+)NCBIGRCr8
mRatBN7.22226,797,303 - 226,808,892 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2226,797,303 - 226,808,892 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2234,543,562 - 234,555,115 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02232,443,298 - 232,454,851 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02227,307,972 - 227,319,527 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02243,550,655 - 243,562,243 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2243,550,627 - 243,687,857 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02262,090,818 - 262,102,977 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42235,799,396 - 235,811,584 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12235,786,135 - 235,797,838 (+)NCBI
Celera2218,954,198 - 218,965,645 (+)NCBICelera
Cytogenetic Map2q44NCBI
Adh1c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554968,136,279 - 8,149,496 (+)NCBIChiLan1.0ChiLan1.0
LOC100970753
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2397,415,305 - 97,432,225 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1497,698,981 - 97,715,496 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0491,756,817 - 91,773,056 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14102,418,515 - 102,435,079 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4102,388,575 - 102,435,079 (-)Ensemblpanpan1.1panPan2
LOC100512795
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8121,020,969 - 121,041,506 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18121,020,683 - 121,041,735 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28130,164,997 - 130,185,238 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Adh1
711 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:611
Count of miRNA genes:419
Interacting mature miRNAs:477
Transcripts:ENSMUST00000004232, ENSMUST00000159159, ENSMUST00000161799, ENSMUST00000162032
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
27226732Tibmd3_mtibia midshaft diameter 3, 10 week (mouse)396607316147805636Mouse
1300752Ap6q_malcohol preference 6 QTL (mouse)Not determined3100372912147045722Mouse
27226733Tibmd6_mtibia midshaft diameter 6, 16 week (mouse)3101307316149805637Mouse
1302093Orgwq5_morgan weight QTL 5 (mouse)Not determined3107376936147304689Mouse
1300619Cdcs1_mcytokine deficiency colitis susceptibility 1 (mouse)Not determined3109834882143835005Mouse
1301381Bomb1_mbone marrow pre-B 1 (mouse)Not determined3111133243145133417Mouse
1301100Bdt2_mbone density traits 2 (mouse)Not determined3114736617148736784Mouse
10043919Afpq8_mabdominal fat percent QTL 8 (mouse)Not determined3119057332153057456Mouse
1558868Ses9_msalmonella enteritidis susceptibility 9 (mouse)Not determined3119057332153057456Mouse
4141935Tgq15_mtriglyceride QTL 15 (mouse)Not determined119318586153318586Mouse
4142449Tgq14_mtriglyceride QTL 14 (mouse)Not determined119318586153318586Mouse
1302151Lprm2_mlymphoproliferation modifier 2 (mouse)Not determined3119778857153779044Mouse
10412240Alpq6_malcohol preference QTL 6 (mouse)Not determined3120772078154772078Mouse
4142245Pstc1_mperiosteal circumference 1 (mouse)Not determined3126270248159745316Mouse
1301218Letohc1_mlow ethanol consumption 1 (mouse)Not determined3126352986159745316Mouse
1301347Fpli_mfasting plasma insulin (mouse)Not determined3126460514159745316Mouse
1301563Alcp3_malcohol preference locus 3 (mouse)Not determined3130736935159745316Mouse
11039523Tbbr1_mTrypanosoma brucei brucei response 1 (mouse)3130849375159745316Mouse
1300753Eae10_msusceptibility to experimental allergic encephalomyelitis 10 (mouse)Not determined3131736617148451178Mouse
10412120Ccs3_mcolon cancer susceptibility 3 (mouse)Not determined3131754536146017669Mouse
1301528Loco1_mlocomotor activity 1 (mouse)Not determined3133461893159745316Mouse

Markers in Region
Adh1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv373137,942,312 - 137,942,644UniSTSGRCm37
Celera3144,686,426 - 144,686,758UniSTS
Cytogenetic Map3G3UniSTS
cM Map371.2UniSTS
cM Map371.2UniSTS
AI194826  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383138,288,786 - 138,288,878UniSTSGRCm38
MGSCv373137,951,750 - 137,951,842UniSTSGRCm37
Celera3144,695,870 - 144,695,962UniSTS
Cytogenetic Map3G3UniSTS
cM Map371.2UniSTS
Whitehead/MRC_RH31538.92UniSTS
GDB:187387  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383138,286,773 - 138,286,952UniSTSGRCm38
MGSCv373137,949,737 - 137,949,916UniSTSGRCm37
Celera3144,693,857 - 144,694,036UniSTS
Cytogenetic Map3G3UniSTS
cM Map371.2UniSTS
40.MMHAP17FRF10.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383138,282,080 - 138,282,273UniSTSGRCm38
MGSCv373137,945,044 - 137,945,237UniSTSGRCm37
Celera3144,689,164 - 144,689,357UniSTS
Cytogenetic Map3G3UniSTS
cM Map371.2UniSTS
Whitehead_YAC3 UniSTS
M18480  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383138,290,623 - 138,290,739UniSTSGRCm38
MGSCv373137,953,587 - 137,953,703UniSTSGRCm37
Celera3144,697,707 - 144,697,823UniSTS
Cytogenetic Map3G3UniSTS
cM Map371.2UniSTS
Whitehead_YAC3 UniSTS
RH94448  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383138,286,703 - 138,286,829UniSTSGRCm38
MGSCv373137,949,667 - 137,949,793UniSTSGRCm37
Celera3144,693,787 - 144,693,913UniSTS
Cytogenetic Map3G3UniSTS
cM Map371.2UniSTS
Adh1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3G3UniSTS
Adh1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3G3UniSTS
Adh1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3G3UniSTS
Adh1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383138,279,348 - 138,279,680UniSTSGRCm38
MGSCv373137,942,312 - 137,942,644UniSTSGRCm37
Celera3144,686,426 - 144,686,758UniSTS
Cytogenetic Map3G3UniSTS
cM Map371.2UniSTS
Adh1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3G3UniSTS
cM Map371.2UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_007409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC079682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH001840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH001841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI256543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI326887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC013477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC054467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD355981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV044803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M22611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z32540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000004232   ⟹   ENSMUSP00000004232
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3137,983,255 - 137,996,459 (+)Ensembl
GRCm38.p6 Ensembl3138,277,494 - 138,290,698 (+)Ensembl
RefSeq Acc Id: ENSMUST00000159159   ⟹   ENSMUSP00000124688
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3137,983,412 - 137,996,459 (+)Ensembl
GRCm38.p6 Ensembl3138,277,651 - 138,290,698 (+)Ensembl
RefSeq Acc Id: ENSMUST00000161799
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3137,983,406 - 137,986,713 (+)Ensembl
GRCm38.p6 Ensembl3138,277,645 - 138,280,952 (+)Ensembl
RefSeq Acc Id: ENSMUST00000162032
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3137,966,752 - 137,988,542 (+)Ensembl
GRCm38.p6 Ensembl3138,260,991 - 138,282,781 (+)Ensembl
RefSeq Acc Id: NM_007409   ⟹   NP_031435
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393137,983,346 - 137,996,459 (+)NCBI
GRCm383138,277,585 - 138,290,698 (+)NCBI
MGSCv373137,940,609 - 137,953,655 (+)RGD
Celera3144,684,702 - 144,697,775 (+)RGD
cM Map3 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_031435   ⟸   NM_007409
- UniProtKB: P00329 (UniProtKB/Swiss-Prot),   Q3UKA4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000124688   ⟸   ENSMUST00000159159
RefSeq Acc Id: ENSMUSP00000004232   ⟸   ENSMUST00000004232
Protein Domains
Enoyl reductase (ER)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P00329-F1-model_v2 AlphaFold P00329 1-375 view protein structure

Promoters
RGD ID:6833351
Promoter ID:MM_KWN:36232
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day3,   Kidney,   Liver,   Lung
Transcripts:ENSMUST00000004232
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363137,940,334 - 137,940,834 (+)MPROMDB
RGD ID:6847717
Promoter ID:MM_ACW:33456
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver,   Lung,   Spleen
Transcripts:ADH1.DSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363137,945,461 - 137,945,961 (+)MPROMDB
RGD ID:6882480
Promoter ID:EPDNEW_M4691
Type:initiation region
Name:Adh1_1
Description:Mus musculus alcohol dehydrogenase 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm383138,277,651 - 138,277,711EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:87921 AgrOrtholog
Ensembl Genes ENSMUSG00000055301
  ENSMUSG00000074207 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000004232 ENTREZGENE
  ENSMUST00000004232.10 UniProtKB/Swiss-Prot
  ENSMUST00000159159.2 UniProtKB/TrEMBL
Gene3D-CATH Medium-chain alcohol dehydrogenases, catalytic domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ADH_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADH_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADH_Zn_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GroES-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKS_ER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:11522 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:87921 ENTREZGENE
NCBI Gene 11522 ENTREZGENE
PANTHER ALCOHOL DEHYDROGENASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ALCOHOL DEHYDROGENASE 1A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ADH_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADH_zinc_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB ADH1C RGD
PhenoGen Adh1 PhenoGen
PROSITE ADH_ZINC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PKS_ER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50129 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt ADH1_MOUSE UniProtKB/Swiss-Prot
  E0CXV3_MOUSE UniProtKB/TrEMBL
  P00329 ENTREZGENE
  Q3UKA4 ENTREZGENE, UniProtKB/TrEMBL