Gene: Alox12 (arachidonate 12-lipoxygenase)  Mus musculus

Symbol: Alox12
Name: arachidonate 12-lipoxygenase
Description: ENCODES a protein that exhibits arachidonate 12-lipoxygenase activity (ortholog); INVOLVED IN negative regulation of apoptotic process; positive regulation of cell proliferation; cellular component movement (ortholog); PARTICIPATES IN lipoxygenase mediated pathway of arachidonic acid metabolism; arachidonic acid metabolic pathway; ASSOCIATED WITH impaired skin barrier function; increased platelet aggregation; thrombosis; ASSOCIATED WITH Lung Neoplasms; Obesity; Albuminuria (ortholog); FOUND IN cytosol (ortholog); sarcolemma (ortholog); INTERACTS WITH (S)-nicotine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 12S-lipoxygenase; 12S-LOX; 9930022G08Rik; Alox12p; arachidonate 12-lipoxygenase, 12S-type; OTTMUSP00000006289; P-12LO; platelet-type lipoxygenase 12
Orthologs: Homo sapiens : ALOX12 (arachidonate 12-lipoxygenase)  HGNC
Rattus norvegicus : Alox12 (arachidonate 12-lipoxygenase)
Latest Assembly: Mouse Genome Assembly Build 37
Position:
MapChrPositionStrandSource
Mouse Genome Assembly GRCm381170,241,455 - 70,255,341-NCBI
Mouse cM Map1142.99 NCBI
Mouse Celera Assembly1177,785,930 - 77,799,829-NCBI
Mouse Genome Assembly Build 371170,054,957 - 70,068,843-NCBI
Mouse Genome Assembly Build 36.11170,054,957 - 70,068,843-NCBI
Mouse Cytogenetic Map11 B3 NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Mouse Genome Assembly Build 37)

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on Alox12
Entrez Gene
Ensembl Gene
Genome Browser
MGI Report
NCBI Map Viewer
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RGD Object Information
RGD ID: 1322470
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2013-04-02
Status: ACTIVE