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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:testosterone biosynthetic pathway
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Accession:PW:0000778 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis of testosterone, a C19-steroid hormone secreted primarily in the testes and ovaries and to a lesser extend by the adrenal glands.
Synonyms:related_synonym: testosterone biosynthetic process
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testosterone biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974 		JBrowse link
G Fdx1 ferredoxin 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 8:61,164,839...61,183,645
Ensembl chr 8:61,164,839...61,183,583 		JBrowse link
G Fdxr ferredoxin reductase ISO RGD PMID:18821018 RGD:2325883 NCBI chr10:101,006,845...101,015,582
Ensembl chr10:101,006,849...101,015,542 		JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 ISO RGD PMID:15583024 RGD:4889549 NCBI chr19:62,662,320...62,733,944
Ensembl chr19:62,662,098...62,733,943 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 ISO RGD PMID:18821018 RGD:2325883 NCBI chr17:1,032,958...1,064,283
Ensembl chr17:1,032,958...1,064,283 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ISO RGD PMID:15583024 RGD:4889549 NCBI chr 2:188,858,574...188,864,694 JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 ISO RGD PMID:15583024 RGD:4889549 NCBI chr 2:188,784,614...188,812,535
Ensembl chr 2:188,784,614...188,790,569 		JBrowse link
G Por cytochrome p450 oxidoreductase ISO RGD PMID:18821018 RGD:2325883 NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:35,514,846...35,548,903 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 6:27,178,089...27,217,588
Ensembl chr 6:27,178,079...27,217,588 		JBrowse link
G Star steroidogenic acute regulatory protein TAS RGD PMID:18821018 RGD:2325883 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447 		JBrowse link
G Sts steroid sulfatase ISO RGD PMID:21693170 RGD:6893583 NCBI chr  X:46,102,524...46,110,868
Ensembl chr  X:46,102,548...46,111,104 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 1:84,582,011...84,639,001 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    classic metabolic pathway 1853
      lipid metabolic pathway 490
        isoprenoid metabolic pathway 95
          isoprenoid biosynthetic pathway 82
            steroid biosynthetic pathway 82
              steroid hormone biosynthetic pathway 55
                C19-steroid hormone biosynthetic pathway 14
                  testosterone biosynthetic pathway 14
paths to the root