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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:pentose phosphate pathway
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Accession:PW:0000045 term browser browse the term
Definition:Those metabolic reactions involved in the generation of reducing equivalents and five carbon (pentose) sugars. The oxidative phase is irreversible; the non-oxidative is reversible.
Synonyms:related_synonym: hexose monophosphate pathway (shunt);   pentose phosphate shunt;   phosphogluconate pathway
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pentose phosphate pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldoa aldolase, fructose-bisphosphate A IEA
ISO 		KEGG
SMPDB		 SMP:00031 rno:00030 NCBI chr 1:190,832,820...190,838,021
Ensembl chr 1:190,832,820...190,838,211 		JBrowse link
G Aldoart2 aldolase 1 A retrogene 2 ISO SMPDB SMP:00031 NCBI chr 6:78,674,945...78,676,635
Ensembl chr 6:78,673,353...78,680,406 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B IEA KEGG rno:00030 NCBI chr 5:68,684,541...68,697,582
Ensembl chr 5:68,684,542...68,716,740 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C IEA KEGG rno:00030 NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,715,489...63,719,133 		JBrowse link
G Dera deoxyribose-phosphate aldolase ISO SMPDB SMP:00031 NCBI chr 4:172,394,971...172,473,746
Ensembl chr 4:172,394,962...172,490,142 		JBrowse link
G Fbp1 fructose-bisphosphatase 1 IEA
ISO 		KEGG
SMPDB		 SMP:00031 rno:00030 NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,213,492...2,235,746 		JBrowse link
G Fbp2 fructose-bisphosphatase 2 IEA KEGG rno:00030 NCBI chr17:2,241,767...2,259,371
Ensembl chr17:2,241,975...2,259,366 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IEA
ISO
IDA 		KEGG
SMPDB
RGD		 PMID:2843500 SMP:00031 rno:00030, RGD:1599574 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144 		JBrowse link
G Gpi glucose-6-phosphate isomerase IEA
ISO 		KEGG
SMPDB		 SMP:00031 rno:00030 NCBI chr 1:95,965,389...95,996,932
Ensembl chr 1:95,965,396...95,993,261 		JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) IEA KEGG rno:00030 NCBI chr 5:165,717,456...165,753,158
Ensembl chr 5:165,721,654...165,753,125 		JBrowse link
G Pfkl phosphofructokinase, liver type IEA
ISO 		KEGG
SMPDB		 SMP:00031 rno:00030 NCBI chr20:10,663,907...10,685,967
Ensembl chr20:10,663,955...10,685,966 		JBrowse link
G Pfkm phosphofructokinase, muscle IEA KEGG rno:00030 NCBI chr 7:131,100,684...131,138,250
Ensembl chr 7:131,100,753...131,138,248 		JBrowse link
G Pfkp phosphofructokinase, platelet IEA KEGG rno:00030 NCBI chr17:68,639,749...68,704,055
Ensembl chr17:68,639,481...68,705,752 		JBrowse link
G Pgd phosphogluconate dehydrogenase IDA
ISO 		SMPDB
RGD		 PMID:2843500 SMP:00031, RGD:1599574 NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:164,865,830...164,882,029 		JBrowse link
G Pgls 6-phosphogluconolactonase IEA
ISO 		KEGG
SMPDB		 SMP:00031 rno:00030 NCBI chr16:18,334,299...18,339,785
Ensembl chr16:18,334,299...18,339,785 		JBrowse link
G Pgm1 phosphoglucomutase 1 IEA
ISO 		KEGG
SMPDB		 SMP:00031 rno:00030 NCBI chr 5:119,710,734...119,770,159
Ensembl chr 5:119,710,737...119,770,159 		JBrowse link
G Prps1 phosphoribosyl pyrophosphate synthetase 1 IEA KEGG rno:00030 NCBI chr  X:108,920,663...108,942,713
Ensembl chr  X:108,920,651...108,942,711 		JBrowse link
G Prps1l1 phosphoribosyl pyrophosphate synthetase 1-like 1 IEA
ISO 		KEGG
SMPDB		 SMP:00031 rno:00030 NCBI chr 6:57,412,331...57,414,021
Ensembl chr 6:57,411,794...57,415,712 		JBrowse link
G Prps2 phosphoribosyl pyrophosphate synthetase 2 IEA KEGG rno:00030 NCBI chr  X:30,592,845...30,630,127
Ensembl chr  X:30,593,019...30,630,126 		JBrowse link
G Rbks ribokinase IEA
ISO 		KEGG
SMPDB		 SMP:00031 rno:00030 NCBI chr 6:30,467,724...30,544,284
Ensembl chr 6:30,467,726...30,544,294 		JBrowse link
G Rgn regucalcin IEA KEGG rno:00030 NCBI chr  X:4,172,537...4,190,112
Ensembl chr  X:4,172,537...4,190,251 		JBrowse link
G Rpe ribulose-5-phosphate-3-epimerase IDA
ISO
IEA 		SMPDB
KEGG
RGD		 PMID:2843500 SMP:00031 rno:00030, RGD:1599574 NCBI chr 9:75,640,867...75,661,009
Ensembl chr 9:75,640,982...75,661,643 		JBrowse link
G Rpia ribose 5-phosphate isomerase A IDA
ISO
IEA 		SMPDB
KEGG
RGD		 PMID:2843500 SMP:00031 rno:00030, RGD:1599574 NCBI chr 4:104,282,081...104,307,732
Ensembl chr 4:104,282,081...104,307,718 		JBrowse link
G Taldo1 transaldolase 1 IEA
ISO
IDA 		KEGG
SMPDB
RGD		 PMID:2843500 SMP:00031 rno:00030, RGD:1599574 NCBI chr 1:205,923,196...205,933,526
Ensembl chr 1:205,923,165...205,933,535 		JBrowse link
G Tkt transketolase IEA
ISO
IDA 		KEGG
SMPDB
RGD		 PMID:2843500 SMP:00031 rno:00030, RGD:1599574 NCBI chr16:5,729,381...5,755,170
Ensembl chr16:5,729,991...5,756,431 		JBrowse link
G Tktl1 transketolase-like 1 IEA KEGG rno:00030 NCBI chr  X:157,105,455...157,138,510
Ensembl chr  X:157,105,495...157,138,503 		JBrowse link
G Tktl2 transketolase-like 2 IEA KEGG rno:00030 NCBI chr16:27,969,009...27,976,353
Ensembl chr16:27,968,871...27,976,442 		JBrowse link
pentose phosphate pathway - non-oxidative phase term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpe ribulose-5-phosphate-3-epimerase TAS RGD PMID:12721358 RGD:1641814 NCBI chr 9:75,640,867...75,661,009
Ensembl chr 9:75,640,982...75,661,643 		JBrowse link
G Rpia ribose 5-phosphate isomerase A TAS RGD PMID:12721358 RGD:1641814 NCBI chr 4:104,282,081...104,307,732
Ensembl chr 4:104,282,081...104,307,718 		JBrowse link
G Taldo1 transaldolase 1 IDA
TAS 		RGD PMID:8477719 PMID:12721358 RGD:1641803, RGD:1641814 NCBI chr 1:205,923,196...205,933,526
Ensembl chr 1:205,923,165...205,933,535 		JBrowse link
G Tkt transketolase TAS
IDA 		RGD PMID:9924800 PMID:16116031 PMID:12721358 RGD:1641798, RGD:1580394, RGD:1641814 NCBI chr16:5,729,381...5,755,170
Ensembl chr16:5,729,991...5,756,431 		JBrowse link
pentose phosphate pathway - oxidative phase term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase ISO RGD PMID:15466941 RGD:1625539 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144 		JBrowse link
G Pgd phosphogluconate dehydrogenase ISO RGD PMID:15466941 RGD:1625539 NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:164,865,830...164,882,029 		JBrowse link
G Pgls 6-phosphogluconolactonase IDA RGD PMID:971315 RGD:2311501 NCBI chr16:18,334,299...18,339,785
Ensembl chr16:18,334,299...18,339,785 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    classic metabolic pathway 1853
      carbohydrate metabolic pathway 526
        glucose metabolic pathway 153
          pentose phosphate pathway 27
            pentose phosphate pathway - non-oxidative phase + 4
            pentose phosphate pathway - oxidative phase 3
paths to the root