Rimbp2 (RIMS binding protein 2) - Rat Genome Database

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Gene: Rimbp2 (RIMS binding protein 2) Rattus norvegicus
Analyze
Symbol: Rimbp2
Name: RIMS binding protein 2
RGD ID: 708533
Description: Predicted to enable voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels and voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential. Predicted to be a structural constituent of presynaptic active zone. Predicted to be involved in neuromuscular synaptic transmission; regulation of calcium-dependent activation of synaptic vesicle fusion; and regulation of presynaptic membrane potential. Predicted to be located in plasma membrane. Predicted to be active in calyx of Held; glutamatergic synapse; and presynaptic active zone cytoplasmic component. Orthologous to human RIMBP2 (RIMS binding protein 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC266780; Rbp2; RIM binding protein 2; RIM-BP2; RIMS-binding protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81233,383,646 - 33,582,259 (+)NCBIGRCr8
mRatBN7.21227,747,615 - 27,946,256 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1227,747,980 - 27,956,763 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1228,962,795 - 29,085,556 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01229,573,367 - 29,696,125 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01228,556,444 - 28,754,898 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01231,393,229 - 31,605,567 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1231,530,699 - 31,620,760 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01233,319,996 - 33,529,398 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41228,809,987 - 29,012,169 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11228,851,920 - 28,872,012 (+)NCBI
Celera1229,442,290 - 29,640,007 (+)NCBICelera
Cytogenetic Map12q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. The RIM/NIM family of neuronal C2 domain proteins. Interactions with Rab3 and a new class of Src homology 3 domain proteins. Wang Y, etal., J Biol Chem 2000 Jun 30;275(26):20033-44.
Additional References at PubMed
PMID:15057822   PMID:17855024   PMID:19389623   PMID:22871113   PMID:27671655   PMID:30661983  


Genomics

Comparative Map Data
Rimbp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81233,383,646 - 33,582,259 (+)NCBIGRCr8
mRatBN7.21227,747,615 - 27,946,256 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1227,747,980 - 27,956,763 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1228,962,795 - 29,085,556 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01229,573,367 - 29,696,125 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01228,556,444 - 28,754,898 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01231,393,229 - 31,605,567 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1231,530,699 - 31,620,760 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01233,319,996 - 33,529,398 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41228,809,987 - 29,012,169 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11228,851,920 - 28,872,012 (+)NCBI
Celera1229,442,290 - 29,640,007 (+)NCBICelera
Cytogenetic Map12q13NCBI
RIMBP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812130,396,133 - 130,716,299 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12130,396,133 - 130,768,228 (-)EnsemblGRCh38hg38GRCh38
GRCh3712130,880,678 - 131,200,844 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612129,446,634 - 129,568,363 (-)NCBINCBI36Build 36hg18NCBI36
Celera12130,494,857 - 130,616,297 (-)NCBICelera
Cytogenetic Map12q24.33NCBI
HuRef12127,866,583 - 127,988,111 (-)NCBIHuRef
CHM1_112130,700,550 - 130,823,261 (-)NCBICHM1_1
T2T-CHM13v2.012130,433,406 - 130,754,746 (-)NCBIT2T-CHM13v2.0
Rimbp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395128,834,852 - 129,030,636 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5128,834,855 - 129,030,550 (-)EnsemblGRCm39 Ensembl
GRCm385128,757,788 - 128,953,644 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5128,757,791 - 128,953,486 (-)EnsemblGRCm38mm10GRCm38
MGSCv375129,266,276 - 129,459,237 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365129,072,499 - 129,268,070 (-)NCBIMGSCv36mm8
MGSCv365127,024,716 - 127,087,061 (-)NCBIMGSCv36mm8
Celera5125,792,301 - 125,891,098 (-)NCBICelera
Cytogenetic Map5G1.3NCBI
cM Map567.91NCBI
Rimbp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554821,332,778 - 1,428,748 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554821,326,628 - 1,431,358 (+)NCBIChiLan1.0ChiLan1.0
RIMBP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210138,456,797 - 138,782,376 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112138,453,316 - 138,848,361 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012128,009,575 - 128,338,009 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112132,222,052 - 132,538,029 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12132,225,056 - 132,305,103 (-)Ensemblpanpan1.1panPan2
RIMBP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1261,519,489 - 1,744,011 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl261,645,591 - 1,744,020 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha261,719,625 - 1,944,681 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0261,765,398 - 1,991,479 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl261,765,218 - 2,010,409 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1261,827,412 - 1,926,413 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0261,798,409 - 2,023,366 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0261,706,066 - 1,932,688 (+)NCBIUU_Cfam_GSD_1.0
Rimbp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118123,214,028 - 123,318,323 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366601,435,019 - 1,482,958 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366601,433,535 - 1,601,912 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RIMBP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1424,394,750 - 24,722,235 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11424,394,793 - 24,722,237 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21426,227,904 - 26,295,566 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RIMBP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111125,770,331 - 126,170,664 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037118,919,840 - 119,239,707 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rimbp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474727,108,508 - 27,144,190 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474727,107,951 - 27,245,303 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rimbp2
1222 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2592
Count of miRNA genes:352
Interacting mature miRNAs:490
Transcripts:ENSRNOT00000033379, ENSRNOT00000067867
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121983578938193007Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
70169Eae13Experimental allergic encephalomyelitis QTL 130.032nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)122413920236638073Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382528064557Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)122423477731894213Rat
737822Alc10Alcohol consumption QTL 102.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)121961087040218516Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961088935682913Rat
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
631543Bp83Blood pressure QTL 835.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121555082638478808Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)121587265332974238Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
1300157Rf21Renal function QTL 214.4renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)12931821632103380Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12844949028302290Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
61416Pia4Pristane induced arthritis QTL 48.4joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)121363552330827399Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121363552335682913Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961087042828880Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122032881946669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat

Markers in Region
BE097070  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21227,926,789 - 27,926,949 (+)MAPPERmRatBN7.2
Rnor_6.01231,586,102 - 31,586,261NCBIRnor6.0
Rnor_6.01231,570,753 - 31,570,912NCBIRnor6.0
Rnor_5.01233,509,936 - 33,510,095UniSTSRnor5.0
Rnor_5.01233,497,812 - 33,497,971UniSTSRnor5.0
RGSC_v3.41228,992,643 - 28,992,802UniSTSRGSC3.4
Celera1229,620,473 - 29,620,632UniSTS
RH 3.4 Map12462.2UniSTS
Cytogenetic Map12q14UniSTS
BG381331  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21227,805,719 - 27,805,873 (+)MAPPERmRatBN7.2
mRatBN7.25152,287,859 - 152,288,013 (+)MAPPERmRatBN7.2
Rnor_6.05158,503,116 - 158,503,269NCBIRnor6.0
Rnor_6.01231,451,559 - 31,451,712NCBIRnor6.0
Rnor_5.01233,379,165 - 33,379,318UniSTSRnor5.0
Rnor_5.05162,230,100 - 162,230,253UniSTSRnor5.0
RGSC_v3.45158,819,605 - 158,819,758UniSTSRGSC3.4
RGSC_v3.41228,870,401 - 28,870,554UniSTSRGSC3.4
Celera1229,500,218 - 29,500,371UniSTS
Celera5150,657,808 - 150,657,961UniSTS
RH 3.4 Map51046.8UniSTS
Cytogenetic Map5q36UniSTS
Cytogenetic Map12q14UniSTS
BF386435  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21227,811,031 - 27,811,225 (+)MAPPERmRatBN7.2
Rnor_6.01231,457,271 - 31,457,464NCBIRnor6.0
Rnor_5.01233,384,330 - 33,384,523UniSTSRnor5.0
RGSC_v3.41228,875,671 - 28,875,864UniSTSRGSC3.4
Celera1229,505,489 - 29,505,682UniSTS
RH 3.4 Map12461.0UniSTS
Cytogenetic Map12q14UniSTS
BE105245  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21227,946,055 - 27,946,206 (+)MAPPERmRatBN7.2
Rnor_6.01231,605,367 - 31,605,517NCBIRnor6.0
Rnor_5.01233,529,201 - 33,529,351UniSTSRnor5.0
RGSC_v3.41229,011,972 - 29,012,122UniSTSRGSC3.4
Celera1229,639,810 - 29,639,960UniSTS
RH 3.4 Map12468.7UniSTS
Cytogenetic Map12q14UniSTS
BF399187  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21227,810,948 - 27,811,167 (+)MAPPERmRatBN7.2
Rnor_6.01231,457,188 - 31,457,406NCBIRnor6.0
Rnor_5.01233,384,247 - 33,384,465UniSTSRnor5.0
RGSC_v3.41228,875,588 - 28,875,806UniSTSRGSC3.4
Celera1229,505,406 - 29,505,624UniSTS
RH 3.4 Map12460.8UniSTS
Cytogenetic Map12q14UniSTS
BF390440  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21227,945,316 - 27,945,480 (+)MAPPERmRatBN7.2
Rnor_6.01231,604,628 - 31,604,791NCBIRnor6.0
Rnor_5.01233,528,462 - 33,528,625UniSTSRnor5.0
Celera1229,639,071 - 29,639,234UniSTS
RH 3.4 Map12506.8UniSTS
Cytogenetic Map12q14UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 31 6
Low 3 37 24 8 18 8 7 10 43 29 39 11 7
Below cutoff 6 13 13 1 13 1 1 2 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001100488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC118310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF199336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000033379   ⟹   ENSRNOP00000030915
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1227,900,155 - 27,956,763 (+)Ensembl
Rnor_6.0 Ensembl1231,530,699 - 31,602,083 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000067867   ⟹   ENSRNOP00000059643
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1227,747,980 - 27,956,763 (+)Ensembl
Rnor_6.0 Ensembl1231,530,699 - 31,602,565 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000086078   ⟹   ENSRNOP00000073070
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1227,747,980 - 27,946,253 (+)Ensembl
Rnor_6.0 Ensembl1231,536,951 - 31,620,760 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000100361   ⟹   ENSRNOP00000080836
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1227,747,980 - 27,946,253 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000107331   ⟹   ENSRNOP00000097882
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1227,747,980 - 27,946,253 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115151   ⟹   ENSRNOP00000087009
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1227,884,038 - 27,944,846 (+)Ensembl
RefSeq Acc Id: NM_001100488   ⟹   NP_001093958
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81233,383,793 - 33,582,259 (+)NCBI
mRatBN7.21227,747,760 - 27,946,253 (+)NCBI
Rnor_6.01231,393,229 - 31,605,564 (+)NCBI
Rnor_5.01233,319,996 - 33,529,398 (+)NCBI
RGSC_v3.41228,809,987 - 29,012,169 (+)RGD
Celera1229,442,290 - 29,640,007 (+)RGD
Sequence:
RefSeq Acc Id: XM_039089126   ⟹   XP_038945054
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81233,436,212 - 33,582,257 (+)NCBI
mRatBN7.21227,800,195 - 27,946,256 (+)NCBI
RefSeq Acc Id: XM_039089127   ⟹   XP_038945055
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81233,383,648 - 33,582,257 (+)NCBI
mRatBN7.21227,747,615 - 27,946,256 (+)NCBI
RefSeq Acc Id: XM_039089128   ⟹   XP_038945056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81233,466,167 - 33,582,257 (+)NCBI
mRatBN7.21227,830,151 - 27,946,256 (+)NCBI
RefSeq Acc Id: XM_039089129   ⟹   XP_038945057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81233,466,452 - 33,582,257 (+)NCBI
mRatBN7.21227,830,565 - 27,946,256 (+)NCBI
RefSeq Acc Id: XM_063271094   ⟹   XP_063127164
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81233,468,402 - 33,582,257 (+)NCBI
RefSeq Acc Id: XM_063271095   ⟹   XP_063127165
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81233,383,646 - 33,582,257 (+)NCBI
RefSeq Acc Id: XM_063271096   ⟹   XP_063127166
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81233,383,646 - 33,582,257 (+)NCBI
RefSeq Acc Id: XM_063271097   ⟹   XP_063127167
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81233,383,655 - 33,582,257 (+)NCBI
RefSeq Acc Id: XM_063271098   ⟹   XP_063127168
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81233,466,457 - 33,582,257 (+)NCBI
RefSeq Acc Id: XM_063271099   ⟹   XP_063127169
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81233,383,654 - 33,582,257 (+)NCBI
RefSeq Acc Id: XM_063271100   ⟹   XP_063127170
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81233,383,654 - 33,582,257 (+)NCBI
RefSeq Acc Id: XM_063271102   ⟹   XP_063127172
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81233,436,224 - 33,582,257 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001093958   ⟸   NM_001100488
- UniProtKB: A0A8I5ZR68 (UniProtKB/TrEMBL),   A0A8I6A6H1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000059643   ⟸   ENSRNOT00000067867
RefSeq Acc Id: ENSRNOP00000030915   ⟸   ENSRNOT00000033379
RefSeq Acc Id: ENSRNOP00000073070   ⟸   ENSRNOT00000086078
RefSeq Acc Id: XP_038945055   ⟸   XM_039089127
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K4J8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945054   ⟸   XM_039089126
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K4J8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945056   ⟸   XM_039089128
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K4J8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945057   ⟸   XM_039089129
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K4J8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000087009   ⟸   ENSRNOT00000115151
RefSeq Acc Id: ENSRNOP00000080836   ⟸   ENSRNOT00000100361
RefSeq Acc Id: ENSRNOP00000097882   ⟸   ENSRNOT00000107331
RefSeq Acc Id: XP_063127165   ⟸   XM_063271095
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063127166   ⟸   XM_063271096
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063127169   ⟸   XM_063271099
- Peptide Label: isoform X5
- UniProtKB: A6J0T2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127170   ⟸   XM_063271100
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063127167   ⟸   XM_063271097
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063127172   ⟸   XM_063271102
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063127168   ⟸   XM_063271098
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063127164   ⟸   XM_063271094
- Peptide Label: isoform X1
Protein Domains
Fibronectin type-III   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JIR1-F1-model_v2 AlphaFold Q9JIR1 1-1049 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708533 AgrOrtholog
BioCyc Gene G2FUF-19467 BioCyc
Ensembl Genes ENSRNOG00000022893 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000033379.5 UniProtKB/TrEMBL
  ENSRNOT00000067867.5 UniProtKB/TrEMBL
  ENSRNOT00000086078.2 UniProtKB/TrEMBL
  ENSRNOT00000100361 ENTREZGENE
  ENSRNOT00000100361.1 UniProtKB/TrEMBL
  ENSRNOT00000107331.1 UniProtKB/TrEMBL
  ENSRNOT00000115151.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 Domains UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIM-BP_SH3_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIM-BP_SH3_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIMBP1/2/3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:266780 UniProtKB/TrEMBL
NCBI Gene 266780 ENTREZGENE
PANTHER PTHR14234 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR14234:SF18 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SH3_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rimbp2 PhenoGen
PRINTS SH3DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000022893 RatGTEx
SMART FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K4J8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZR68 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A6H1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AV27_RAT UniProtKB/TrEMBL
  A6J0T0_RAT UniProtKB/TrEMBL
  A6J0T2 ENTREZGENE, UniProtKB/TrEMBL
  D4A2L1_RAT UniProtKB/TrEMBL
  F1LSC8_RAT UniProtKB/TrEMBL
  Q9JIR1 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-05-05 Rimbp2  RIMS binding protein 2  Rimbp2  RIM binding protein 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Rimbp2  RIM binding protein 2  LOC266780    Symbol updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference