Rimbp2 (RIMS binding protein 2) - Rat Genome Database

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Gene: Rimbp2 (RIMS binding protein 2) Heterocephalus glaber
Analyze
Symbol: Rimbp2
Name: RIMS binding protein 2
RGD ID: 18931651
Description: ENCODES a protein that exhibits structural constituent of presynaptic active zone (ortholog); voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels (ortholog); voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential (ortholog); INVOLVED IN regulation of calcium-dependent activation of synaptic vesicle fusion (ortholog); regulation of presynaptic membrane potential (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN calyx of Held (ortholog); glutamatergic synapse (ortholog); presynaptic active zone cytoplasmic component (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: RIMS-binding protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474727,108,508 - 27,144,190 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474727,107,951 - 27,245,303 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rimbp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474727,108,508 - 27,144,190 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474727,107,951 - 27,245,303 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
RIMBP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812130,396,133 - 130,716,299 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12130,396,133 - 130,768,228 (-)EnsemblGRCh38hg38GRCh38
GRCh3712130,880,678 - 131,200,844 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612129,446,634 - 129,568,363 (-)NCBINCBI36Build 36hg18NCBI36
Celera12130,494,857 - 130,616,297 (-)NCBICelera
Cytogenetic Map12q24.33NCBI
HuRef12127,866,583 - 127,988,111 (-)NCBIHuRef
CHM1_112130,700,550 - 130,823,261 (-)NCBICHM1_1
T2T-CHM13v2.012130,433,406 - 130,754,746 (-)NCBIT2T-CHM13v2.0
Rimbp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395128,834,852 - 129,030,636 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5128,834,855 - 129,030,550 (-)EnsemblGRCm39 Ensembl
GRCm385128,757,788 - 128,953,644 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5128,757,791 - 128,953,486 (-)EnsemblGRCm38mm10GRCm38
MGSCv375129,266,276 - 129,459,237 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365129,072,499 - 129,268,070 (-)NCBIMGSCv36mm8
MGSCv365127,024,716 - 127,087,061 (-)NCBIMGSCv36mm8
Celera5125,792,301 - 125,891,098 (-)NCBICelera
Cytogenetic Map5G1.3NCBI
cM Map567.91NCBI
Rimbp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81233,383,646 - 33,582,259 (+)NCBIGRCr8
mRatBN7.21227,747,615 - 27,946,256 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1227,747,980 - 27,956,763 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1228,962,795 - 29,085,556 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01229,573,367 - 29,696,125 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01228,556,444 - 28,754,898 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01231,393,229 - 31,605,567 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1231,530,699 - 31,620,760 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01233,319,996 - 33,529,398 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41228,809,987 - 29,012,169 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11228,851,920 - 28,872,012 (+)NCBI
Celera1229,442,290 - 29,640,007 (+)NCBICelera
Cytogenetic Map12q13NCBI
Rimbp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554821,332,778 - 1,428,748 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554821,326,628 - 1,431,358 (+)NCBIChiLan1.0ChiLan1.0
RIMBP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210138,456,797 - 138,782,376 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112138,453,316 - 138,848,361 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012128,009,575 - 128,338,009 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112132,222,052 - 132,538,029 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12132,225,056 - 132,305,103 (-)Ensemblpanpan1.1panPan2
RIMBP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1261,519,489 - 1,744,011 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl261,645,591 - 1,744,020 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha261,719,625 - 1,944,681 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0261,765,398 - 1,991,479 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl261,765,218 - 2,010,409 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1261,827,412 - 1,926,413 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0261,798,409 - 2,023,366 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0261,706,066 - 1,932,688 (+)NCBIUU_Cfam_GSD_1.0
Rimbp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118123,214,028 - 123,318,323 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366601,435,019 - 1,482,958 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366601,433,535 - 1,601,912 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RIMBP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1424,394,750 - 24,722,235 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11424,394,793 - 24,722,237 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21426,227,904 - 26,295,566 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RIMBP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111125,770,331 - 126,170,664 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037118,919,840 - 119,239,707 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000023854   ⟹   ENSHGLP00000023636
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474727,108,508 - 27,144,190 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000023855   ⟹   ENSHGLP00000023637
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474727,110,034 - 27,144,190 (-)Ensembl
RefSeq Acc Id: XM_021257667   ⟹   XP_021113326
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474727,108,392 - 27,233,770 (-)NCBI
RefSeq Acc Id: XM_021257668   ⟹   XP_021113327
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474727,108,392 - 27,207,796 (-)NCBI
RefSeq Acc Id: XM_021257669   ⟹   XP_021113328
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474727,108,392 - 27,197,977 (-)NCBI
RefSeq Acc Id: XM_021257670   ⟹   XP_021113329
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474727,108,392 - 27,157,773 (-)NCBI
RefSeq Acc Id: XM_021257671   ⟹   XP_021113330
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474727,108,392 - 27,156,931 (-)NCBI
RefSeq Acc Id: XM_021257672   ⟹   XP_021113331
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474727,108,392 - 27,245,303 (-)NCBI
RefSeq Acc Id: XM_021257673   ⟹   XP_021113332
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474727,108,392 - 27,140,612 (-)NCBI
RefSeq Acc Id: XM_021257674   ⟹   XP_021113333
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474727,108,392 - 27,156,618 (-)NCBI
RefSeq Acc Id: XM_021257675   ⟹   XP_021113334
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474727,108,392 - 27,245,301 (-)NCBI
RefSeq Acc Id: XM_021257676   ⟹   XP_021113335
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474727,108,392 - 27,245,301 (-)NCBI
RefSeq Acc Id: XM_021257678   ⟹   XP_021113337
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474727,107,951 - 27,233,750 (-)NCBI
RefSeq Acc Id: XM_021257679   ⟹   XP_021113338
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474727,107,951 - 27,233,749 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021113337   ⟸   XM_021257678
- Peptide Label: isoform X7
- UniProtKB: G5AWP5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021113338   ⟸   XM_021257679
- Peptide Label: isoform X8
- UniProtKB: G5AWP5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021113331   ⟸   XM_021257672
- Peptide Label: isoform X2
RefSeq Acc Id: XP_021113335   ⟸   XM_021257676
- Peptide Label: isoform X6
- UniProtKB: G5AWP5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021113334   ⟸   XM_021257675
- Peptide Label: isoform X5
- UniProtKB: G5AWP5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021113326   ⟸   XM_021257667
- Peptide Label: isoform X1
RefSeq Acc Id: XP_021113327   ⟸   XM_021257668
- Peptide Label: isoform X1
RefSeq Acc Id: XP_021113328   ⟸   XM_021257669
- Peptide Label: isoform X1
RefSeq Acc Id: XP_021113329   ⟸   XM_021257670
- Peptide Label: isoform X1
RefSeq Acc Id: XP_021113330   ⟸   XM_021257671
- Peptide Label: isoform X1
RefSeq Acc Id: XP_021113333   ⟸   XM_021257674
- Peptide Label: isoform X4
RefSeq Acc Id: XP_021113332   ⟸   XM_021257673
- Peptide Label: isoform X3
RefSeq Acc Id: ENSHGLP00000023636   ⟸   ENSHGLT00000023854
RefSeq Acc Id: ENSHGLP00000023637   ⟸   ENSHGLT00000023855


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000016862 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000023854 ENTREZGENE
  ENSHGLT00000023855 ENTREZGENE
Gene3D-CATH Immunoglobulins UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  RIM-BP_SH3_3 UniProtKB/TrEMBL
  RIMBP1/2/3 UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene Rimbp2 ENTREZGENE
PANTHER RIM BINDING PROTEIN-RELATED UniProtKB/TrEMBL
  RIMS-BINDING PROTEIN 2 UniProtKB/TrEMBL
Pfam SH3_2 UniProtKB/TrEMBL
  SH3_9 UniProtKB/TrEMBL
PRINTS SH3DOMAIN UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART FN3 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP Fibronectin type III UniProtKB/TrEMBL
  SH3-domain UniProtKB/TrEMBL
UniProt G5AWP5 ENTREZGENE, UniProtKB/TrEMBL