| 12719824 | Star | steroidogenic acute regulatory protein | ENCODES a protein that exhibits cholesterol binding (inferred); cholesterol transfer activity (inferred); lipid binding (inferred); INVOLVED IN bile acid biosynthetic process (ortholog); cellular response to alkaloid (ortholog); cellular response to antibiotic (ortholog); PARTICIPATES IN aldosterone biosynthetic pathway; cortisol biosynthetic pathway; estradiol biosynthetic pathway; ASSOCIATED WITH Cardiomegaly (ortholog); congenital adrenal hyperplasia (ortholog); Disorders of Environmental Origin (ortholog); FOUND IN mitochondrial crista (ortholog); mitochondrial outer membrane (ortholog); mitochondrion (ortholog) | NW_004936710 | 1523289 | 1530181 | Squirrel | 112 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12560877 | LOC101971809 | stAR-related lipid transfer protein 6-like | | NW_004936534 | 9196294 | 9235489 | Squirrel | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |
| 12695965 | Stard3 | StAR related lipid transfer domain containing 3 | ENCODES a protein that exhibits cholesterol binding (inferred); cholesterol transfer activity (inferred); lipid binding (inferred); INVOLVED IN progesterone biosynthetic process (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN endoplasmic reticulum-endosome membrane contact site (ortholog) | NW_004936490 | 14832067 | 14856330 | Squirrel | 40 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12487530 | Stard4 | StAR related lipid transfer domain containing 4 | ENCODES a protein that exhibits cholesterol binding (inferred); cholesterol transfer activity (inferred); lipid binding (inferred); INVOLVED IN cholesterol import (inferred); cholesterol transport involved in cholesterol storage (inferred); intracellular cholesterol transport (inferred); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasm (ortholog) | NW_004936531 | 5865840 | 5877591 | Squirrel | 22 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12678088 | Stard5 | StAR related lipid transfer domain containing 5 | ENCODES a protein that exhibits bile acid binding (ortholog); INVOLVED IN cholesterol import (inferred); lipid transport (inferred) | NW_004936483 | 19406273 | 19416619 | Squirrel | 10 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12565089 | Stard6 | StAR related lipid transfer domain containing 6 | ENCODES a protein that exhibits lipid binding (inferred); INVOLVED IN lipid transport (inferred) | NW_004936497 | 9457304 | 9475635 | Squirrel | 3 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12645871 | Stard7 | StAR related lipid transfer domain containing 7 | ENCODES a protein that exhibits lipid binding (inferred); molecular carrier activity (inferred); phosphatidylcholine transfer activity (inferred); INVOLVED IN establishment of skin barrier (ortholog); inflammatory response (ortholog); mucociliary clearance (ortholog); ASSOCIATED WITH familial adult myoclonic epilepsy 2 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); mitochondrial intermembrane space (inferred) | NW_004936744 | 302238 | 329189 | Squirrel | 21 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12558019 | Stard8 | StAR related lipid transfer domain containing 8 | ENCODES a protein that exhibits GTPase activator activity (inferred); lipid binding (inferred); INVOLVED IN actin cytoskeleton organization (inferred); regulation of Rho protein signal transduction (inferred); signal transduction (inferred); ASSOCIATED WITH Breast Neoplasms (ortholog); Colorectal Ne oplasms (ortholog) | NW_004936777 | 316332 | 358241 | Squirrel | 8 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12515245 | Stard9 | StAR related lipid transfer domain containing 9 | ENCODES a protein that exhibits ATP binding (inferred); lipid binding (inferred); microtubule binding (inferred); INVOLVED IN microtubule-based movement (inferred); spindle assembly (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); bipolar disorder (ortholog); Developmental Disabiliti es (ortholog); FOUND IN centriole (inferred); cytoplasm (inferred); nucleus (inferred) | NW_004936471 | 5842887 | 5986988 | Squirrel | 16 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12443244 | Stard10 | StAR related lipid transfer domain containing 10 | ENCODES a protein that exhibits lipid binding (inferred); INVOLVED IN bile acid secretion (ortholog); positive regulation of peroxisome proliferator activated receptor signaling pathway (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); int ercellular canaliculus (inferred) | NW_004936498 | 2018736 | 2044897 | Squirrel | 15 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12547417 | Stard13 | StAR related lipid transfer domain containing 13 | ENCODES a protein that exhibits GTPase activator activity (inferred); lipid binding (inferred); INVOLVED IN endothelial cell migration (ortholog); endothelial tube lumen extension (ortholog); negative regulation of cell migration involved in sprouting angiogenesis (ortholog); ASSOCIATED WITH COVID-1 9 (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm (inferred); lipid droplet (inferred); mitochondrial membrane (inferred) | NW_004936472 | 27683939 | 28158362 | Squirrel | 19 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12459140 | LOC101969897 | stAR-related lipid transfer protein 7, mitochondrial-like | | NW_004936600 | 5229777 | 5231475 | Squirrel | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |
| 12683469 | Stard3nl | STARD3 N-terminal like | ENCODES a protein that exhibits cholesterol binding (inferred); protein homodimerization activity (inferred); INVOLVED IN cholesterol transport (inferred); vesicle tethering to endoplasmic reticulum (inferred); FOUND IN endoplasmic reticulum membrane (inferred); endoplasmic reticulum-endosome membra ne contact site (inferred); endosome (inferred) | NW_004936478 | 13489743 | 13537225 | Squirrel | 20 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12674125 | Kics2 | KICSTOR subunit 2 | INVOLVED IN cellular response to amino acid starvation (inferred); cellular response to glucose starvation (inferred); negative regulation of TORC1 signaling (inferred); ASSOCIATED WITH autosomal recessive intellectual devel opmental disorder 83 (ortholog); polycystic ovary syndrome (ortholog); FOUND IN KICSTOR complex (inferred); lysosomal membrane (inferred) | NW_004936545 | 2577388 | 2602698 | Squirrel | 15 | description | gene, protein-coding, MODEL [RefSeq] |
| 12516757 | Kptn | kaptin, actin binding protein | ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); INVOLVED IN actin filament organization (inferred); cellular response to amino acid starvation (inferred); cellular response to glucose star arvation (inferred); ASSOCIATED WITH autosomal recessive intellectual developmental disorder 41 (ortholog); COVID-19 (ortholog); genetic disease (ortholog); FOUND IN actin cytoskeleton (inferred); filamentous actin (inferred); KICSTOR complex (inferred) | NW_004936664 | 1146003 | 1155571 | Squirrel | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 12723873 | Rpl17 | ribosomal protein L17 | ENCODES a protein that exhibits large ribosomal subunit rRNA binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); positive regulation of G1/S transition of mitotic cell cycle (ortholog); response to amino acid star weight:700;'>starvation (ortholog); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; ASSOCIATED WITH Myocardial Ischemia (ortholog); FOUND IN A band (ortholog); cytosol (ortholog); cytosolic large ribosomal subunit (ortholog) | NW_004936497 | 13457328 | 13460606 | Squirrel | 29 | description | gene, protein-coding, MODEL [RefSeq] |
| 12513989 | Rragb | Ras related GTP binding B | ENCODES a protein that exhibits GTP binding (ortholog); INVOLVED IN cellular response to amino acid starvation (inferred); cellular response to amino acid stimulus (inferred); cellular response to leucine starvation (inferre d); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH autistic disorder (ortholog); FOUND IN cytoplasm (inferred); Gtr1-Gtr2 GTPase complex (inferred); lysosomal membrane (inferred) | NW_004936819 | 946874 | 988531 | Squirrel | 46 | description | gene, protein-coding, MODEL [RefSeq] |
| 12672738 | Stbd1 | starch binding domain 1 | ENCODES a protein that exhibits carbohydrate binding (inferred); cargo receptor activity (inferred); enzyme binding (inferred); INVOLVED IN glycogen catabolic process (inferred); glycogen metabolic process (inferred); glycophagy (inferred); FOUND IN endoplasmic reticulum (inferred); endoplasmic reti culum membrane (inferred); membrane (inferred) | NW_004936676 | 300244 | 304206 | Squirrel | 29 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12577774 | LOC101961766 | STARD3 N-terminal-like protein | | NW_004936472 | 21052065 | 21201912 | Squirrel | | name | gene, pseudo, MODEL [RefSeq] |
| 12657840 | LOC101969854 | starch-binding domain-containing protein 1-like | | NW_004936903 | 243865 | 246283 | Squirrel | | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12615103 | Gys2 | glycogen synthase 2 | ENCODES a protein that exhibits alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity (ortholog); D-glucose binding (ortholog); INVOLVED IN glycogen biosynthetic process (ortholog); glycogen metabolic process (ortholog); response to glucose (ortholog); PARTICIPATES IN congenital sucrase- isomaltase deficiency pathway; glycogen biosynthetic pathway; glycogen metabolic pathway; ASSOCIATED WITH genetic disease (ortholog); glycogen storage disease (ortholog); Glycogen Storage Disease 0, Liver (ortholog); FOUND IN cell cortex (ortholog); cortical actin cytoskeleton (ortholog); cytoskeleton (ortholog) | NW_004936548 | 5256185 | 5309758 | Squirrel | 42 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12620837 | Gys1 | glycogen synthase 1 | ENCODES a protein that exhibits alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity (ortholog); D-glucose binding (ortholog); INVOLVED IN glycogen biosynthetic process (ortholog); glycogen metabolic process (ortholog); heart development (ortholog); PARTICIPATES IN glycogen biosynthetic pathway; insulin responsive facilitative sugar transporter mediated glucose transport pathway; ASSOCIATED WITH cardiovascular system disease (ortholog); genetic disease (ortholog); Glycogen Storage Disease 0, Muscle (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); inclusion body (inferred) | NW_004936664 | 2978546 | 2995145 | Squirrel | 43 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12557961 | Acp5 | acid phosphatase 5, tartrate resistant | ENCODES a protein that exhibits acid phosphatase activity (ortholog); hydrolase activity (ortholog); INVOLVED IN bone morphogenesis (ortholog); bone resorption (ortholog); cellular response to zinc ion starvation (ortholog); ASSOCIATED WITH Alveolar Bone Loss (o rtholog); Combined Immunodeficiency with Autoimmunity and Spondylometaphyseal Dysplasia (ortholog); Desbuquois dysplasia (ortholog); FOUND IN extracellular space (ortholog) | NW_004936659 | 1598252 | 1642615 | Squirrel | 54 | description | gene, protein-coding, MODEL [RefSeq] |
| 12525086 | Ambra1 | autophagy and beclin 1 regulator 1 | ENCODES a protein that exhibits GTPase binding (inferred); protein phosphatase activator activity (inferred); protein phosphatase binding (inferred); INVOLVED IN autophagy (ortholog); cellular response to starvation (ortholog); negative regulation of cardiac mus cle cell apoptotic process (ortholog); PARTICIPATES IN inositol metabolic pathway; mitochondrial autophagy pathway; phosphoinositide metabolic pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); esophageal atresia (ortholog); multiple system atrophy (ortholog); FOUND IN mitochondrion (ortholog) | NW_004936562 | 2493823 | 2676868 | Squirrel | 81 | description | gene, protein-coding, MODEL [RefSeq] |
| 12665599 | Asns | asparagine synthetase (glutamine-hydrolyzing) | ENCODES a protein that exhibits asparagine synthase (glutamine-hydrolyzing) activity (ortholog); identical protein binding (ortholog); INVOLVED IN cellular response to glucose starvation (ortholog); cellular response to hormone stimulus (ortholog); L-asparagine biosynthetic process (ortholog); PARTICIPATES IN Canavan disease pathway; ASSOCIATED WITH Asparagine Synthetase Deficiency (ortholog); Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytosol (inferred) | NW_004936585 | 2834202 | 2854740 | Squirrel | 41 | description | gene, protein-coding, MODEL [RefSeq] |
| 12491242 | Atf2 | activating transcription factor 2 | ENCODES a protein that exhibits cAMP response element binding (ortholog); protein-containing complex binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN adipose tissue development (ortholog); amelogenesis (ortholog); cellular response to leucine star tarvation (ortholog); PARTICIPATES IN adenosine signaling pathway; interleukin-12 signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); basal cell carcinoma (ortholog); disease of cellular proliferation (ortholog); FOUND IN CCAAT-binding factor complex (ortholog) | NW_004936509 | 4729984 | 4826367 | Squirrel | 146 | description | gene, protein-coding, MODEL [RefSeq] |
| 12702737 | Atg4b | autophagy related 4B cysteine peptidase | ENCODES a protein that exhibits cysteine-type endopeptidase activity (inferred); cysteine-type peptidase activity (inferred); endopeptidase activity (inferred); INVOLVED IN cellular response to starvation (ortholog); otolith mineralization completed early in dev elopment (ortholog); positive regulation of protein catabolic process (ortholog); PARTICIPATES IN autophagy pathway; FOUND IN autophagosome (inferred); autophagosome membrane (inferred); cytoplasm (inferred) | NW_004936745 | 291311 | 308469 | Squirrel | 44 | description | gene, protein-coding, MODEL [RefSeq] |
| 12632586 | Bmt2 | base methyltransferase of 25S rRNA 2 homolog | ENCODES a protein that exhibits methyltransferase activity (inferred); protein-containing complex binding (inferred); S-adenosyl-L-methionine binding (inferred); INVOLVED IN cellular response to amino acid starvation (inferred); cellular response to methionine ( inferred); methylation (inferred) | NW_004936589 | 5578566 | 5657093 | Squirrel | 11 | description | gene, protein-coding, MODEL [RefSeq] |
| 12662605 | Cadps2 | calcium dependent secretion activator 2 | ENCODES a protein that exhibits lipid binding (inferred); metal ion binding (inferred); INVOLVED IN cellular response to starvation (ortholog); hematopoietic stem cell homeostasis (ortholog); positive regulation of exocytosis (ortholog); ASSOCIATED WITH autism s pectrum disorder (ortholog); autistic disorder (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN centrosome (inferred); ciliary basal body (inferred); cilium (inferred) | NW_004936605 | 2505064 | 3012322 | Squirrel | 34 | description | gene, protein-coding, MODEL [RefSeq] |
| 12546366 | Castor1 | cytosolic arginine sensor for mTORC1 subunit 1 | ENCODES a protein that exhibits arginine binding (inferred); identical protein binding (inferred); molecular sensor activity (inferred); INVOLVED IN cellular response to amino acid starvation (inferred); cellular response to L-arginine (inferred); negative regul ation of TORC1 signaling (inferred); PARTICIPATES IN mTOR signaling pathway; FOUND IN cytosol (inferred); GATOR2 complex (inferred) | NW_004936904 | 372609 | 376878 | Squirrel | 23 | description | gene, protein-coding, MODEL [RefSeq] |
| 12651262 | Chka | choline kinase alpha | ENCODES a protein that exhibits ATP binding (ortholog); choline binding (ortholog); choline kinase activity (ortholog); INVOLVED IN cellular response to glucose starvation (ortholog); choline metabolic process (ortholog); ethanolamine metabolic process (ortholog ); PARTICIPATES IN glycerophospholipid metabolic pathway; ASSOCIATED WITH colon adenoma (ortholog); colon cancer (ortholog); epilepsy (ortholog); FOUND IN lipid droplet (ortholog) | NW_004936599 | 2031953 | 2068423 | Squirrel | 44 | description | gene, protein-coding, MODEL [RefSeq] |
| 12499378 | Cpeb4 | cytoplasmic polyadenylation element binding protein 4 | ENCODES a protein that exhibits mRNA 3'-UTR binding (inferred); mRNA regulatory element binding translation repressor activity (inferred); nucleic acid binding (inferred); INVOLVED IN cellular response to amino acid stimulus (ortholog); cellular response to decreased oxygen levels (ortholog); cellul ar response to glucose starvation (ortholog); ASSOCIATED WITH liver cirrhosis (ortholog); portal hypertension (ortholog); primary biliary cholangitis (ortholog); FOUND IN dendrite (ortholog); endoplasmic reticulum (ortholog); postsynapse (ortholog) | NW_004936609 | 1793027 | 1858586 | Squirrel | 38 | description | gene, protein-coding, MODEL [RefSeq] |
| 155262968 | DAP | death associated protein | ENCODES a protein that exhibits death domain binding (inferred); INVOLVED IN apoptotic signaling pathway (inferred); cellular response to amino acid starvation (inferred); negative regulation of autophagy (inferred) | | | | Squirrel | 7 | description | gene, protein-coding |
| 12694774 | Depdc5 | DEP domain containing 5, GATOR1 subcomplex subunit | ENCODES a protein that exhibits GTPase activator activity (inferred); protein-containing complex binding (inferred); small GTPase binding (inferred); INVOLVED IN cellular response to amino acid starvation (inferred); intracellular signal transduction (inferred); negative regulation of TORC1 signaling (inferred); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH autosomal dominant nocturnal frontal lobe epilepsy (ortholog); benign epilepsy with centrotemporal spikes (ortholog); Developmental and Epileptic Encephalopathy 111 (ortholog); FOUND IN Cul3-RING ubiquitin ligase complex (inferred); cytoplasm (inferred); cytosol (inferred) | NW_004936755 | 871935 | 1024538 | Squirrel | 47 | description | gene, protein-coding, MODEL [RefSeq] |
| 12701312 | Dnajc15 | DnaJ heat shock protein family (Hsp40) member C15 | ENCODES a protein that exhibits ATPase activator activity (inferred); INVOLVED IN cellular response to starvation (ortholog); negative regulation of mitochondrial electron transport, NADH to ubiquinone (ortholog); negative regulation of protein-containing comple x assembly (ortholog); ASSOCIATED WITH melanoma (ortholog); FOUND IN mitochondrial inner membrane (inferred); mitochondrion (inferred); PAM complex, Tim23 associated import motor (inferred) | NW_004936747 | 800070 | 864299 | Squirrel | 14 | description | gene, protein-coding, MODEL [RefSeq] |
| 12502500 | Dsc2 | desmocollin 2 | ENCODES a protein that exhibits calcium ion binding (inferred); gamma-catenin binding (inferred); INVOLVED IN cellular response to starvation (ortholog); ASSOCIATED WITH acute myocardial infarction (ortholog); arrhythmogenic right ventricular cardiomyopathy (ort holog); arrhythmogenic right ventricular dysplasia 1 (ortholog); FOUND IN adherens junction (inferred); cell-cell junction (inferred); cytoplasmic vesicle (inferred) | NW_004936682 | 2057331 | 2091034 | Squirrel | 64 | description | gene, protein-coding, MODEL [RefSeq] |
| 12503130 | Ehmt2 | euchromatic histone lysine methyltransferase 2 | ENCODES a protein that exhibits C2H2 zinc finger domain binding (inferred); H1-4K26 methyltransferase activity (inferred); histone H3K27 methyltransferase activity (inferred); INVOLVED IN behavioral response to cocaine (ortholog); cellular response to cocaine (ortholog); cellular response to star tyle='font-weight:700;'>starvation (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); acute myeloid leukemia (ortholog); alopecia areata (ortholog); FOUND IN chromatin (ortholog); nucleolus (ortholog); nucleus (ortholog) | NW_004936727 | 1648451 | 1663294 | Squirrel | 120 | description | gene, protein-coding, MODEL [RefSeq] |
| 12513144 | Eif2a | eukaryotic translation initiation factor 2A | ENCODES a protein that exhibits mRNA binding (inferred); ribosome binding (inferred); translation initiation factor activity (inferred); INVOLVED IN positive regulation of signal transduction (ortholog); protein phosphorylation (ortholog); response to amino acid star span>vation (ortholog); PARTICIPATES IN ceramide signaling pathway; endoplasmic reticulum stress - the unfolded protein response pathway; transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH borna disease (ortholog); dystonia 33 (ortholog); Marinesco-Sjogren syndrome (ortholog); FOUND IN cytoplasm (inferred); cytosolic small ribosomal subunit (inferred); eukaryotic translation initiation factor 2 complex (inferred) | NW_004936758 | 960305 | 992152 | Squirrel | 38 | description | gene, protein-coding, MODEL [RefSeq] |
| 12515924 | Eif2ak4 | eukaryotic translation initiation factor 2 alpha kinase 4 | ENCODES a protein that exhibits ATP binding (inferred); eukaryotic translation initiation factor 2alpha kinase activity (inferred); kinase activity (inferred); INVOLVED IN cellular response to starvation (ortholog); cellular response to UV (ortholog); endoplasmi c reticulum unfolded protein response (ortholog); ASSOCIATED WITH amino acid metabolic disorder (ortholog); genetic disease (ortholog); hair disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred) | NW_004936471 | 3423792 | 3527089 | Squirrel | 80 | description | gene, protein-coding, MODEL [RefSeq] |
| 12633094 | Eif2b1 | eukaryotic translation initiation factor 2B subunit alpha | ENCODES a protein that exhibits GDP binding (ortholog); GTP binding (ortholog); translation initiation factor activity (ortholog); INVOLVED IN negative regulation of guanyl-nucleotide exchange factor activity (ortholog); response to amino acid starvation (orthol og); response to glucose (ortholog); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH Animal Disease Models (ortholog); epilepsy (ortholog); genetic disease (ortholog); FOUND IN eukaryotic translation initiation factor 2 complex (ortholog); eukaryotic translation initiation factor 2B complex (ortholog) | NW_004936558 | 1196111 | 1205321 | Squirrel | 54 | description | gene, protein-coding, MODEL [RefSeq] |
| 12633253 | Elapor1 | endosome-lysosome associated apoptosis and autophagy regulator 1 | INVOLVED IN autophagosome assembly (inferred); autophagy (inferred); cellular response to starvation (inferred); FOUND IN endoplasmic reticulum membrane (inferred); extracellular exosome (inferred); Golgi apparatus (inferred) | NW_004936704 | 653434 | 736660 | Squirrel | 24 | description | gene, protein-coding, MODEL [RefSeq] |
| 12541061 | Epm2aip1 | EPM2A interacting protein 1 | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN positive regulation of glycogen (starch) synthase activity (ortholog); positive regulation of glycogen biosynthetic process (ortholog); response to insulin (ortholog); ASSOCIATED W ITH hereditary nonpolyposis colorectal cancer type 2 (ortholog); Lynch syndrome (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic side of endoplasmic reticulum membrane (inferred); nucleus (inferred) | NW_004936473 | 26548847 | 26556334 | Squirrel | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 12474497 | Fads1 | fatty acid desaturase 1 | ENCODES a protein that exhibits acyl-CoA 6-desaturase activity (ortholog); oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (ortholog); INVOLVED IN arachidonate metabolic process (ortholog); cellular response to starvation (ortholog); long-chain fatty acid biosynthetic process (ortholog); PARTICIPATES IN alpha-linolenic acid metabolic pathway; linoleic acid metabolic pathway; ASSOCIATED WITH Cardiac Fibrosis (ortholog); Chemical and Drug Induced Liver Injury (ortholog); Colorectal Neoplasms (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); membrane (inferred); mitochondrion (inferred) | NW_004936581 | 1312199 | 1327046 | Squirrel | 47 | description | gene, protein-coding, MODEL [RefSeq] |
| 12630177 | Fbxo22 | F-box protein 22 | INVOLVED IN cellular response to starvation (ortholog); nucleocytoplasmic transport (ortholog); positive regulation of proteasomal ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH Tayoun-Maawali syndrome (ortholog); FOUND IN cytoplasm (i nferred); nucleus (inferred) | NW_004936471 | 36232749 | 36255772 | Squirrel | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 12719853 | Fnip1 | folliculin interacting protein 1 | ENCODES a protein that exhibits ATPase inhibitor activity (inferred); enzyme activator activity (inferred); enzyme binding (inferred); INVOLVED IN cellular response to starvation (ortholog); immature B cell differentiation (ortholog); negative regulation of cell population proliferation (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH genetic disease (ortholog); immunodeficiency 93 (ortholog); Wolff-Parkinson-White syndrome (ortholog); FOUND IN cytoplasm (ortholog) | NW_004936647 | 3329097 | 3428170 | Squirrel | 47 | description | gene, protein-coding, MODEL [RefSeq] |
| 12512808 | Foxa3 | forkhead box A3 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN cellular response to starvation (ortholog); hematopoietic stem cell homeostasis (ortholog); intracellular glucose homeostasis (ortholog); PA RTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH Experimental Diabetes Mellitus (ortholog); Prostatic Neoplasms (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred) | NW_004936706 | 2196530 | 2202924 | Squirrel | 42 | description | gene, protein-coding, MODEL [RefSeq] |
| 12588844 | Gas2l1 | growth arrest specific 2 like 1 | ENCODES a protein that exhibits actin filament binding (inferred); cytoskeletal anchor activity (inferred); microtubule binding (inferred); INVOLVED IN cellular response to starvation (ortholog); negative regulation of microtubule depolymerization (ortholog); AS SOCIATED WITH acute myeloid leukemia (ortholog); FOUND IN microtubule (ortholog) | NW_004936657 | 3327363 | 3333087 | Squirrel | 20 | description | gene, protein-coding, MODEL [RefSeq] |
| 12447688 | Gcgr | glucagon receptor | ENCODES a protein that exhibits glucagon receptor activity (ortholog); peptide hormone binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); cellular response to starvation (ortholog); PARTICIPATES IN G protein mediated signaling pathway via Galphas family; glucagon signaling pathway; ASSOCIATED WITH ACTH-independent macronodular adrenal hyperplasia 1 (ortholog); Mahvash disease (ortholog); maturity-onset diabetes of the young type 1 (ortholog); FOUND IN endosome (ortholog) | NW_004936594 | 5347789 | 5351852 | Squirrel | 42 | description | gene, protein-coding, MODEL [RefSeq] |
| 12554568 | Gck | glucokinase | ENCODES a protein that exhibits ADP binding (ortholog); ATP binding (ortholog); D-glucose binding (ortholog); INVOLVED IN carbohydrate phosphorylation (ortholog); cellular response to glucose starvation (ortholog); cellular response to insulin stimulus (ortholog ); PARTICIPATES IN congenital sucrase-isomaltase deficiency pathway; forkhead class A signaling pathway; galactokinase deficiency pathway; ASSOCIATED WITH Bone Marrow Failure Syndrome 2 (ortholog); Congenital Hyperinsulinism (ortholog); coronary artery disease (ortholog); FOUND IN actin filament (ortholog); basal cortex (ortholog); cell cortex (ortholog) | NW_004936478 | 19104477 | 19118915 | Squirrel | 205 | description | gene, protein-coding, MODEL [RefSeq] |
| 12594122 | Gcn1 | GCN1 activator of EIF2AK4 | ENCODES a protein that exhibits molecular adaptor activity (inferred); protein kinase regulator activity (inferred); protein serine/threonine kinase activator activity (inferred); INVOLVED IN cellular response to amino acid starvation (inferred); GCN2-mediated s ignaling (inferred); protein-RNA covalent cross-linking repair (inferred); ASSOCIATED WITH fetal akinesia deformation sequence syndrome 1 (ortholog); FOUND IN cytoplasm (ortholog) | NW_004936668 | 718961 | 786101 | Squirrel | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 12457849 | Glul | glutamate-ammonia ligase | ENCODES a protein that exhibits ATP binding (ortholog); dynein light chain binding (ortholog); glutamate binding (ortholog); INVOLVED IN ammonia assimilation cycle (ortholog); cellular response to starvation (ortholog); glutamate metabolic process (ortholog); PA RTICIPATES IN 2-hydroxyglutaric aciduria pathway; glutamic acid/glutamate metabolic pathway; homocarnosinosis pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Carotid Atherosclerosis (ortholog); congenital glutamine deficiency (ortholog); FOUND IN cell projection (ortholog); myelin sheath (ortholog); perikaryon (ortholog) | NW_004936481 | 7293301 | 7301416 | Squirrel | 112 | description | gene, protein-coding, MODEL [RefSeq] |
| 12707272 | Gpr155 | G protein-coupled receptor 155 | ENCODES a protein that exhibits cholesterol binding (inferred); INVOLVED IN cellular response to amino acid starvation (inferred); cellular response to cholesterol (inferred); cognition (inferred); ASSOCIATED WITH autistic disorder (ortholog); Hepatomegaly (orth olog); FOUND IN lysosomal membrane (inferred); membrane (inferred) | NW_004936509 | 4202587 | 4252865 | Squirrel | 14 | description | gene, protein-coding, MODEL [RefSeq] |
| 12631688 | Gpt2 | glutamic--pyruvic transaminase 2 | ENCODES a protein that exhibits L-alanine:2-oxoglutarate aminotransferase activity (inferred); pyridoxal phosphate binding (inferred); transaminase activity (inferred); INVOLVED IN cellular response to insulin stimulus (ortholog); gluconeogenesis (ortholog); response to star '>starvation (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Chronic Hepatitis C (ortholog); genetic disease (ortholog); FOUND IN extracellular space (ortholog); mitochondrion (ortholog) | NW_004936475 | 262558 | 299766 | Squirrel | 31 | description | gene, protein-coding, MODEL [RefSeq] |
| 12517799 | Hfe | homeostatic iron regulator | ENCODES a protein that exhibits peptide antigen binding (ortholog); INVOLVED IN acute-phase response (ortholog); cellular response to iron ion starvation (ortholog); female pregnancy (ortholog); ASSOCIATED WITH Abdominal Pain (ortholog); acute lymphoblastic leuk emia (ortholog); alcohol-associated liver disease (ortholog); FOUND IN apical part of cell (ortholog); MHC class I protein complex (ortholog); terminal web (ortholog) | NW_004936671 | 1940079 | 1947574 | Squirrel | 162 | description | gene, protein-coding, MODEL [RefSeq] |
| 12653810 | Higd1a | HIG1 hypoxia inducible domain family member 1A | INVOLVED IN cellular response to glucose starvation (ortholog); cellular response to hypoxia (ortholog); negative regulation of apoptotic process (ortholog); FOUND IN nucleus (ortholog) | NW_004936695 | 2330939 | 2341387 | Squirrel | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 12464356 | Hnrnpa1 | heterogeneous nuclear ribonucleoprotein A1 | ENCODES a protein that exhibits DNA binding (ortholog); DNA/DNA annealing activity (ortholog); G-rich strand telomeric DNA binding (ortholog); INVOLVED IN alternative mRNA splicing, via spliceosome (ortholog); cellular response to epidermal growth factor stimulus (ortholog); cellular response to glu cose starvation (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); amyotrophic lateral sclerosis type 20 (ortholog); Animal Disease Models (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleoplasmic periphery of the nuclear pore complex (ortholog) | NW_004936512 | 11481017 | 11487737 | Squirrel | 91 | description | gene, protein-coding, MODEL [RefSeq] |
| 12466510 | Hnrnpl | heterogeneous nuclear ribonucleoprotein L | ENCODES a protein that exhibits mRNA 3'-UTR binding (ortholog); mRNA CDS binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); circadian rhythm (ortholog); negative regulation of mRNA splicing, via spliceosome (ortholog); PARTICI PATES IN spliceosome pathway; ASSOCIATED WITH brain cancer (ortholog); Breast Neoplasms (ortholog); Disease Progression (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog) | NW_004936661 | 1793791 | 1806564 | Squirrel | 48 | description | gene, protein-coding, MODEL [RefSeq] |
| 124887680 | Krt20 | keratin 20 | INVOLVED IN cellular response to starvation (ortholog); intermediate filament organization (ortholog); regulation of protein secretion (ortholog); ASSOCIATED WITH adenocarcinoma (ortholog); Cecal Neoplasms (ortholog); colorectal cancer (ortholog); FOUND IN cytop lasm (ortholog); cytosol (ortholog) | | | | Squirrel | 20 | description | gene, protein-coding, MODEL [RefSeq] |
| 12692767 | Lars1 | leucyl-tRNA synthetase 1 | ENCODES a protein that exhibits aminoacyl-tRNA deacylase activity (inferred); aminoacyl-tRNA ligase activity (inferred); ATP binding (inferred); INVOLVED IN aminoacyl-tRNA metabolism involved in translational fidelity (inferred); cellular response to amino acid star pan>vation (inferred); cellular response to amino acid stimulus (inferred); ASSOCIATED WITH infantile liver failure syndrome 1 (ortholog); microcephaly (ortholog); sensorineural hearing loss (ortholog); FOUND IN aminoacyl-tRNA synthetase multienzyme complex (inferred); cytoplasm (inferred); cytosol (inferred) | NW_004936504 | 8500024 | 8568477 | Squirrel | 44 | description | gene, protein-coding, MODEL [RefSeq] |
| 12637551 | Map1lc3a | microtubule associated protein 1 light chain 3 alpha | ENCODES a protein that exhibits phospholipid binding (inferred); ubiquitin protein ligase binding (inferred); INVOLVED IN autophagy (ortholog); autophagy of mitochondrion (ortholog); cellular response to amino acid starvation (ortholog); PARTICIPATES IN autophag y pathway; ASSOCIATED WITH Acute Experimental Pancreatitis (ortholog); acute myocardial infarction (ortholog); amyotrophic lateral sclerosis (ortholog); FOUND IN autophagosome (ortholog); autophagosome membrane (ortholog); cytoplasm (ortholog) | NW_004936561 | 6104748 | 6106348 | Squirrel | 106 | description | gene, protein-coding, MODEL [RefSeq] |
| 12671045 | Max | MYC associated transcriptional regulator X | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); INVOLVED IN cellular response to peptide hormone stimulus (ortholog); cellular response to starvation (ortholog); negative regulation of gene expression (ortholog); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); Hereditary Paraganglioma-Pheochromocytoma Syndromes (ortholog); lung small cell carcinoma (ortholog); FOUND IN dendrite (ortholog); Myc-Max complex (ortholog); nucleus (ortholog) | NW_004936495 | 8728941 | 8755742 | Squirrel | 77 | description | gene, protein-coding, MODEL [RefSeq] |
| 12533617 | Mfsd11 | major facilitator superfamily domain containing 11 | INVOLVED IN response to food (ortholog); response to starvation (ortholog); FOUND IN membrane (inferred) | NW_004936594 | 1778930 | 1805945 | Squirrel | 4 | description | gene, protein-coding, MODEL [RefSeq] |
| 12732705 | Mfsd2a | MFSD2 lysolipid transporter A, lysophospholipid | ENCODES a protein that exhibits fatty acid transmembrane transporter activity (inferred); long-chain fatty acid transmembrane transporter activity (inferred); lysophosphatidylcholine flippase activity (inferred); INVOLVED IN brain development (ortholog); cellular response to star :700;'>starvation (ortholog); cognition (ortholog); ASSOCIATED WITH cryptorchidism (ortholog); genetic disease (ortholog); hepatocellular carcinoma (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); lysosome (inferred); membrane (inferred) | NW_004936474 | 21790807 | 21803336 | Squirrel | 70 | description | gene, protein-coding, MODEL [RefSeq] |
| 12473724 | Mios | meiosis regulator for oocyte development | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN cellular response to amino acid starvation (inferred); cellular response to nutrient levels (inferred); central nervous system myelin formation (inferred); PAR TICIPATES IN mTOR signaling pathway; FOUND IN cytoplasm (inferred); cytosol (inferred); GATOR2 complex (inferred) | NW_004936585 | 2296713 | 2331737 | Squirrel | 24 | description | gene, protein-coding, MODEL [RefSeq] |
| 12652885 | Myh13 | myosin heavy chain 13 | ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); ATP binding (inferred); INVOLVED IN cellular response to starvation (ortholog); ASSOCIATED WITH osteoarthritis (ortholog); FOUND IN cytoplasm (inferred); myofibril (infe rred); myosin complex (inferred) | NW_004936595 | 3204487 | 3262459 | Squirrel | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 12650422 | Myod1 | myogenic differentiation 1 | ENCODES a protein that exhibits E-box binding (ortholog); INVOLVED IN cellular response to glucocorticoid stimulus (ortholog); cellular response to oxygen levels (ortholog); cellular response to starvation (ortholog); ASSOCIATED WITH autosomal dominant centronuc lear myopathy (ortholog); congenital diaphragmatic hernia (ortholog); congenital myopathy 17 (ortholog); FOUND IN nucleus (ortholog) | NW_004936528 | 1407187 | 1409683 | Squirrel | 124 | description | gene, protein-coding, MODEL [RefSeq] |
| 12529351 | Npas1 | neuronal PAS domain protein 1 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); protein dimerization activity (inferred); INVOLVED IN maternal behavior (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); star yle='font-weight:700;'>startle response (ortholog); FOUND IN nucleus (inferred) | NW_004936664 | 799864 | 814022 | Squirrel | 20 | description | gene, protein-coding, MODEL [RefSeq] |
| 12453967 | Nr1h3 | nuclear receptor subfamily 1 group H member 3 | ENCODES a protein that exhibits nuclear receptor activity (ortholog); nuclear retinoid X receptor binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN bile acid metabolic process (ortholog); cellular response to starvation (ortholog); d igestive tract development (ortholog); ASSOCIATED WITH abdominal aortic aneurysm (ortholog); atherosclerosis (ortholog); Carotid Atherosclerosis (ortholog); FOUND IN nucleolus (ortholog) | NW_004936562 | 1937665 | 1946680 | Squirrel | 130 | description | gene, protein-coding, MODEL [RefSeq] |
| 155264211 | NUPR2 | nuclear protein 2, transcriptional regulator | INVOLVED IN cellular response to starvation (inferred); DNA damage response (inferred); negative regulation of cell cycle (inferred); FOUND IN nucleus (inferred) | | | | Squirrel | 10 | description | gene, protein-coding |
| 12594516 | Oaz3 | ornithine decarboxylase antizyme 3 | The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamine in cel ls. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis pathway; thus, completing the auto-regulatory circuit. This gene encodes antizyme 3, the third member of the antizyme family. Like antizymes 1 and 2, antizyme 3 inhibits ODC activity and polyamine uptake, however, it does not stimulate ODC degradation. Also, while antizymes 1 and 2 have broad tissue distribution, expression of antizyme 3 is restricted to haploid germ cells in testis, suggesting a distinct role for this antizyme in spermiogenesis. Antizyme 3 gene knockout studies in mice showed that homozygous mutant male mice were infertile, and indicated the likely role of this antizyme in the formation of a rigid connection between the sperm head and tail during spermatogenesis. This transcript initiates translation from a non-AUG (CUG) start codon that is highly conserved amongst the antizyme 3 orthologs. [provided by RefSeq, Aug 2014] | NW_004936580 | 1963372 | 1966086 | Squirrel | 26 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 12668133 | Pdk4 | pyruvate dehydrogenase kinase 4 | ENCODES a protein that exhibits ATP binding (ortholog); pyruvate dehydrogenase (acetyl-transferring) kinase activity (ortholog); INVOLVED IN cellular response to fatty acid (ortholog); cellular response to starvation (ortholog); protein phosphorylation (ortholog ); PARTICIPATES IN pyruvate metabolic pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Experimental Diabetes Mellitus (ortholog); hepatocellular carcinoma (ortholog); FOUND IN mitochondrion (ortholog) | NW_004936585 | 4701012 | 4713421 | Squirrel | 44 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12623019 | Pdp2 | pyruvate dehyrogenase phosphatase catalytic subunit 2 | ENCODES a protein that exhibits [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity (inferred); cation binding (inferred); hydrolase activity (inferred); INVOLVED IN peptidyl-threonine dephosphorylation (ortholog); response to starvation (ortholo g); PARTICIPATES IN pyruvate metabolic pathway; ASSOCIATED WITH Experimental Diabetes Mellitus (ortholog); prostate cancer (ortholog); FOUND IN mitochondrion (inferred) | NW_004936475 | 17139135 | 17146021 | Squirrel | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 12437574 | Pick1 | protein interacting with PRKCA 1 | ENCODES a protein that exhibits actin filament binding (ortholog); Arp2/3 complex binding (ortholog); cytoskeletal protein binding (ortholog); INVOLVED IN AMPA glutamate receptor clustering (ortholog); cellular response to decreased oxygen levels (ortholog); cellular response to glucose star 'font-weight:700;'>starvation (ortholog); PARTICIPATES IN protein kinase C (PKC) signaling pathway; ASSOCIATED WITH amphetamine abuse (ortholog); substance-induced psychosis (ortholog); FOUND IN dendrite (ortholog); dendritic spine (ortholog); dendritic spine cytoplasm (ortholog) | NW_004936492 | 3098196 | 3115921 | Squirrel | 131 | description | gene, protein-coding, MODEL [RefSeq] |
| 12641041 | Pik3c2a | phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha | ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase activity (inferred); 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity (inferred); 1-phosphatidylinositol-4-phosphate 3-kinase activity (inferred); INVOLVED IN autophagosome organization (ortholog); cellular response to star yle='font-weight:700;'>starvation (ortholog); macroautophagy (ortholog); PARTICIPATES IN phosphoinositide metabolic pathway; ASSOCIATED WITH Dwarfism (ortholog); Oculoskeletodental Syndrome (ortholog); type 2 diabetes mellitus (ortholog); FOUND IN clathrin-coated vesicle (inferred); cytoplasm (inferred); cytoplasmic vesicle (inferred) | NW_004936528 | 1845372 | 1964908 | Squirrel | 52 | description | gene, protein-coding, MODEL [RefSeq] |
| 12484544 | Pik3c2b | phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta | ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase activity (inferred); 1-phosphatidylinositol-4-phosphate 3-kinase activity (inferred); ATP binding (inferred); INVOLVED IN autophagosome organization (ortholog); cellular response to starvation (orth olog); macroautophagy (ortholog); ASSOCIATED WITH Neoplasm Metastasis (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); endocytic vesicle (inferred) | NW_004936567 | 314957 | 377544 | Squirrel | 50 | description | gene, protein-coding, MODEL [RefSeq] |
| 12440726 | Pik3c3 | phosphatidylinositol 3-kinase catalytic subunit type 3 | ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase activity (ortholog); INVOLVED IN autophagosome assembly (ortholog); autophagy (ortholog); cellular response to starvation (ortholog); PARTICIPATES IN autophagy pathway; inositol metabolic pathway; p hosphatidylinositol 3-kinase signaling pathway; FOUND IN autolysosome (inferred); cytoplasm (inferred); endosome (inferred) | NW_004936517 | 4009938 | 4145518 | Squirrel | 98 | description | gene, protein-coding, MODEL [RefSeq] |
| 12482272 | Pik3r4 | phosphoinositide-3-kinase regulatory subunit 4 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleotide binding (inferred); INVOLVED IN autophagosome maturation (inferred); cellular response to glucose starvation (inferred); early endosome to late endosome transport (inf erred); PARTICIPATES IN autophagy pathway; inositol metabolic pathway; phosphoinositide metabolic pathway; FOUND IN autophagosome (inferred); axoneme (inferred); cilium (inferred) | NW_004936529 | 4162276 | 4232471 | Squirrel | 50 | description | gene, protein-coding, MODEL [RefSeq] |
| 12485408 | Plin3 | perilipin 3 | INVOLVED IN cellular response to glucose starvation (inferred); lipid droplet disassembly (inferred); lipid storage (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN lipid droplet (ortholog) | NW_004936588 | 2829536 | 2842427 | Squirrel | 18 | description | gene, protein-coding, MODEL [RefSeq] |
| 12463900 | Pmaip1 | phorbol-12-myristate-13-acetate-induced protein 1 | INVOLVED IN apoptotic process (ortholog); cellular response to glucose starvation (ortholog); cellular response to hypoxia (ortholog); PARTICIPATES IN intrinsic apoptotic pathway; ASSOCIATED WITH B-Cell Chronic Lymphocytic Leukemia (ortholog); COVID-19 (ortholog ); substance-related disorder (ortholog); FOUND IN Bcl-2 family protein complex (ortholog); cytosol (ortholog); mitochondrion (ortholog) | NW_004936497 | 4985995 | 4986720 | Squirrel | 57 | description | gene, protein-coding, MODEL [RefSeq] |
| 12579680 | Ppm1d | protein phosphatase, Mg2+/Mn2+ dependent 1D | ENCODES a protein that exhibits cation binding (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN cellular response to starvation (ortholog); DNA damage response, signal transduction by p53 class mediator (ortholog); G2/M transi tion of mitotic cell cycle (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; p38 MAPK signaling pathway; p53 signaling pathway; ASSOCIATED WITH Brain Stem Neoplasms (ortholog); breast cancer (ortholog); Breast Cancer, Familial (ortholog); FOUND IN cytosol (inferred); nucleolus (inferred); nucleoplasm (inferred) | NW_004936490 | 2139201 | 2183850 | Squirrel | 41 | description | gene, protein-coding, MODEL [RefSeq] |
| 12667292 | Ppp1r15a | protein phosphatase 1 regulatory subunit 15A | ENCODES a protein that exhibits eukaryotic initiation factor eIF2 binding (ortholog); molecular adaptor activity (ortholog); protein kinase binding (ortholog); INVOLVED IN cellular response to antibiotic (ortholog); cellular response to calcium ion starvation (o rtholog); cellular response to carbohydrate stimulus (ortholog); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH Acute-On-Chronic Liver Failure (ortholog); Amaurosis Fugax (ortholog); amyotrophic lateral sclerosis (ortholog); FOUND IN cytoplasm (ortholog); endoplasmic reticulum (ortholog); Golgi apparatus (ortholog) | NW_004936664 | 2910609 | 2914205 | Squirrel | 76 | description | gene, protein-coding, MODEL [RefSeq] |
| 12731618 | Ppp1r3f | protein phosphatase 1 regulatory subunit 3F | ENCODES a protein that exhibits glycogen binding (inferred); protein phosphatase 1 binding (inferred); protein phosphatase binding (inferred); INVOLVED IN regulation of glycogen (starch) synthase activity (ortholog); regulation of glycogen biosynthetic process ( ortholog); FOUND IN membrane (inferred); protein phosphatase type 1 complex (inferred) | NW_004936721 | 1137998 | 1153243 | Squirrel | 9 | description | gene, protein-coding, MODEL [RefSeq] |
| 12665006 | Ppp1r3g | protein phosphatase 1 regulatory subunit 3G | ENCODES a protein that exhibits glycogen binding (inferred); protein phosphatase 1 binding (inferred); protein phosphatase binding (inferred); INVOLVED IN glucose homeostasis (ortholog); positive regulation of glycogen (starch) synthase activity (ortholog); posi tive regulation of glycogen biosynthetic process (ortholog); FOUND IN cytoplasm (inferred); protein phosphatase type 1 complex (inferred) | NW_004936534 | 7379443 | 7382752 | Squirrel | 13 | description | gene, protein-coding, MODEL [RefSeq] |
| 12565636 | Prkcd | protein kinase C delta | ENCODES a protein that exhibits calcium,diacylglycerol-dependent serine/threonine kinase activity (ortholog); diacylglycerol-dependent, calcium-independent serine/threonine kinase activity (ortholog); protein kinase binding (ortholog); INVOLVED IN B cell proliferation (ortholog); cellular response t o glucose starvation (ortholog); cellular response to insulin stimulus (ortholog); PARTICIPATES IN ceramide signaling pathway; eicosanoid signaling pathway; endothelin signaling pathway; ASSOCIATED WITH autoimmune lymphoproliferative syndrome type 3 (ortholog); brain ischemia (ortholog); Burns (ortholog); FOUND IN postsynaptic cytosol (ortholog) | NW_004936473 | 3892625 | 3923467 | Squirrel | 177 | description | gene, protein-coding, MODEL [RefSeq] |
| 12617708 | Prkch | protein kinase C eta | ENCODES a protein that exhibits diacylglycerol-dependent, calcium-independent serine/threonine kinase activity (ortholog); protein serine/threonine kinase binding (ortholog); protein serine/threonine kinase inhibitor activity (ortholog); INVOLVED IN cellular response to amino acid star weight:700;'>starvation (ortholog); negative regulation of translation (ortholog); phospholipase C/protein kinase C signal transduction (ortholog); PARTICIPATES IN eicosanoid signaling pathway; endothelin signaling pathway; protein kinase C (PKC) signaling pathway; ASSOCIATED WITH cerebral infarction (ortholog); obesity (ortholog); substance-related disorder (ortholog); FOUND IN cell-cell junction (inferred); cytoplasm (inferred); cytosol (inferred) | NW_004936495 | 5426243 | 5638250 | Squirrel | 52 | description | gene, protein-coding, MODEL [RefSeq] |
| 12736801 | Pwwp2a | PWWP domain containing 2A | ENCODES a protein that exhibits histone binding (ortholog); histone H3K36me3 reader activity (ortholog); NuRD complex binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); regulation of transcriptional start site selection at RNA polymerase II promote r (ortholog); FOUND IN nucleoplasm (ortholog) | NW_004936515 | 3399339 | 3436003 | Squirrel | 18 | description | gene, protein-coding, MODEL [RefSeq] |
| 12625247 | Rnase4 | ribonuclease A family member 4 | ENCODES a protein that exhibits endonuclease activity (inferred); hydrolase activity (inferred); nuclease activity (inferred); INVOLVED IN cellular response to starvation (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Prostatic Neoplasms (o rtholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | NW_004936880 | 41940 | 42988 | Squirrel | 16 | description | gene, protein-coding, MODEL [RefSeq] |
| 12560120 | Rnf152 | ring finger protein 152 | ENCODES a protein that exhibits metal ion binding (inferred); small GTPase binding (inferred); transferase activity (inferred); INVOLVED IN apoptotic process (inferred); cellular response to amino acid starvation (inferred); negative regulation of TORC1 signalin g (inferred); FOUND IN lysosomal membrane (inferred); lysosome (inferred); organelle membrane (inferred) | NW_004936497 | 3357464 | 3421813 | Squirrel | 30 | description | gene, protein-coding, MODEL [RefSeq] |
| 12493615 | Rpl26 | ribosomal protein L26 | ENCODES a protein that exhibits mRNA 5'-UTR binding (inferred); RNA binding (inferred); structural constituent of ribosome (inferred); INVOLVED IN cellular response to ionizing radiation (ortholog); cytoplasmic translation (ortholog); response to amino acid star vation (ortholog); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; ASSOCIATED WITH congenital hypoplastic anemia (ortholog); Diamond-Blackfan anemia (ortholog); Diamond-Blackfan anemia 11 (ortholog); FOUND IN cytosolic large ribosomal subunit (ortholog); cytosolic ribosome (ortholog); synapse (ortholog) | NW_004936595 | 1603913 | 1609125 | Squirrel | 41 | description | gene, protein-coding, MODEL [RefSeq] |
| 12710710 | Rps25 | ribosomal protein S25 | ENCODES a protein that exhibits structural constituent of ribosome (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); ribosomal small subunit assembly (ortholog); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; FOUND IN cytosolic small ribosomal subunit (ortholog) | NW_004936542 | 3974796 | 3977155 | Squirrel | 26 | description | gene, protein-coding, MODEL [RefSeq] |
| 12645292 | Rraga | Ras related GTP binding A | ENCODES a protein that exhibits GTP binding (ortholog); GTPase activity (ortholog); phosphoprotein binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to amino acid stimulus (ortholog); cellular response to nu trient levels (ortholog); PARTICIPATES IN mTOR signaling pathway; FOUND IN cytoplasm (ortholog); FNIP-folliculin RagC/D GAP (ortholog); GATOR1 complex (ortholog) | NW_004936652 | 991832 | 993439 | Squirrel | 50 | description | gene, protein-coding, MODEL [RefSeq] |
| 124917357 | Rragc | Ras related GTP binding C | ENCODES a protein that exhibits enzyme-substrate adaptor activity (inferred); GDP binding (inferred); GTP binding (inferred); INVOLVED IN cellular response to amino acid starvation (inferred); cellular response to amino acid stimulus (inferred); cellular respons e to nutrient levels (inferred); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH follicular lymphoma (ortholog); genetic disease (ortholog); LONG-OLSEN-DISTELMAIER SYNDROME (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); FNIP-folliculin RagC/D GAP (inferred) | | | | Squirrel | 75 | description | gene, protein-coding, MODEL [RefSeq] |
| 12629442 | Rragd | Ras related GTP binding D | ENCODES a protein that exhibits GDP binding (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN cellular response to amino acid starvation (inferred); cellular response to amino acid stimulus (inferred); cellular response to L-leucine (in ferred); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH genetic disease (ortholog); renal hypomagnesemia 7, with or without dilated cardiomyopathy (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); Gtr1-Gtr2 GTPase complex (inferred) | NW_004936510 | 2810028 | 2849792 | Squirrel | 59 | description | gene, protein-coding, MODEL [RefSeq] |
| 12621221 | Sar1b | secretion associated Ras related GTPase 1B | ENCODES a protein that exhibits amino acid sensor activity (ortholog); G protein activity (ortholog); INVOLVED IN cellular response to leucine starvation (ortholog); COPII vesicle coating (ortholog); COPII-coated vesicle cargo loading (ortholog); ASSOCIATED WITH chylomicron retention disease (ortholog); genetic disease (ortholog); Hereditary Pancreatitis (ortholog); FOUND IN COPII vesicle coat (ortholog); endoplasmic reticulum exit site (ortholog); lysosomal membrane (ortholog) | NW_004936647 | 697930 | 723577 | Squirrel | 39 | description | gene, protein-coding, MODEL [RefSeq] |
| 12631172 | Sirt1 | sirtuin 1 | ENCODES a protein that exhibits caspase binding (ortholog); enzyme binding (ortholog); histone deacetylase activity, NAD-dependent (ortholog); INVOLVED IN behavioral response to starvation (ortholog); cardiac muscle cell apoptotic process (ortholog); cellular re sponse to amyloid-beta (ortholog); PARTICIPATES IN histone modification pathway; hypoxia inducible factor pathway; p53 signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Alzheimer's disease (ortholog); amyotrophic lateral sclerosis (ortholog); FOUND IN axon (ortholog); cytoplasm (ortholog); cytosol (ortholog) | NW_004936521 | 10296097 | 10316673 | Squirrel | 421 | description | gene, protein-coding, MODEL [RefSeq] |
| 12598111 | Slc2a1 | solute carrier family 2 member 1 | ENCODES a protein that exhibits D-glucose transmembrane transporter activity (ortholog); kinase binding (ortholog); xenobiotic transmembrane transporter activity (ortholog); INVOLVED IN cellular hyperosmotic response (ortholog); cellular response to glucose star vation (ortholog); cellular response to mechanical stimulus (ortholog); PARTICIPATES IN facilitative sugar transporter mediated glucose transport pathway; Glut1 deficiency syndrome pathway; hypoxia inducible factor pathway; ASSOCIATED WITH alcohol dependence (ortholog); Alcohol-Related Disorders (ortholog); Alzheimer's disease (ortholog); FOUND IN caveola (ortholog); cell-cell junction (ortholog); intercalated disc (ortholog) | NW_004936474 | 24205878 | 24236611 | Squirrel | 171 | description | gene, protein-coding, MODEL [RefSeq] |
| 12515845 | Slc38a3 | solute carrier family 38 member 3 | ENCODES a protein that exhibits neutral L-amino acid:sodium symporter activity (ortholog); INVOLVED IN asparagine transmembrane transport (ortholog); cellular response to potassium ion starvation (ortholog); female pregnancy (ortholog); ASSOCIATED WITH developme ntal and epileptic encephalopathy 102 (ortholog); Dwarfism (ortholog); Endotoxemia (ortholog); FOUND IN basolateral plasma membrane (ortholog) | NW_004936529 | 1749919 | 1765885 | Squirrel | 51 | description | gene, protein-coding, MODEL [RefSeq] |
| 12527117 | Slc39a4 | solute carrier family 39 member 4 | ENCODES a protein that exhibits identical protein binding (inferred); metal ion binding (inferred); metal ion transmembrane transporter activity (inferred); INVOLVED IN cellular response to zinc ion starvation (ortholog); intracellular zinc ion homeostasis (orth olog); zinc ion transport (ortholog); ASSOCIATED WITH acrodermatitis (ortholog); acrodermatitis enteropathica (ortholog); genetic disease (ortholog); FOUND IN endosome (ortholog) | NW_004936470 | 7836612 | 7842262 | Squirrel | 37 | description | gene, protein-coding, MODEL [RefSeq] |
| 12543578 | Slc39a5 | solute carrier family 39 member 5 | ENCODES a protein that exhibits metal ion transmembrane transporter activity (inferred); monoatomic cation:bicarbonate symporter activity (inferred); zinc ion transmembrane transporter activity (inferred); INVOLVED IN cellular response to zinc ion starvation (or tholog); positive regulation of mRNA splicing, via spliceosome (ortholog); ASSOCIATED WITH Myopia 24, Autosomal Dominant (ortholog); retinitis pigmentosa 1 (ortholog); FOUND IN basolateral plasma membrane (inferred); membrane (inferred); plasma membrane (inferred) | NW_004936646 | 638956 | 649501 | Squirrel | 22 | description | gene, protein-coding, MODEL [RefSeq] |
| 12512268 | Slc3a2 | solute carrier family 3 member 2 | ENCODES a protein that exhibits aromatic amino acid transmembrane transporter activity (ortholog); double-stranded RNA binding (ortholog); exogenous protein binding (ortholog); INVOLVED IN amino acid import across plasma membrane (ortholog); cellular response to glucose star '>starvation (ortholog); isoleucine transport (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); autism spectrum disorder (ortholog); Liver Metastasis (ortholog); FOUND IN amino acid transport complex (ortholog); apical plasma membrane (ortholog); apical pole of neuron (ortholog) | NW_004936581 | 424801 | 441592 | Squirrel | 101 | description | gene, protein-coding, MODEL [RefSeq] |
| 12598921 | Slc61a1 | solute carrier family 61 member 1 | ENCODES a protein that exhibits molybdate ion transmembrane transporter activity (inferred); INVOLVED IN response to food (ortholog); response to starvation (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | NW_004936512 | 10545758 | 10548067 | Squirrel | 15 | description | gene, protein-coding, MODEL [RefSeq] |
| 12597467 | Slco2b1 | solute carrier organic anion transporter family member 2B1 | ENCODES a protein that exhibits bile acid transmembrane transporter activity (inferred); prostaglandin transmembrane transporter activity (inferred); secondary active transmembrane transporter activity (inferred); INVOLVED IN cell population proliferation (ortholog); cellular response to iron ion ... (more)pan style='font-weight:700;'>starvation (ortholog); heme import into cell (ortholog); PARTICIPATES IN statin pharmacokinetics pathway; ASSOCIATED WITH liver cancer (ortholog); pancreatic cancer (ortholog); FOUND IN apical plasma membrane (ortholog); plasma membrane (ortholog) | NW_004936498 | 3998537 | 4047436 | Squirrel | 30 | description | gene, protein-coding, MODEL [RefSeq] |
| 12645663 | Smdt1 | single-pass membrane protein with aspartate rich tail 1 | ENCODES a protein that exhibits channel activator activity (inferred); protein-macromolecule adaptor activity (inferred); INVOLVED IN calcium import into the mitochondrion (inferred); calcium ion transport (inferred); cellular response to calcium ion starvation (inferred); FOUND IN mitochondrial inner membrane (ortholog) | NW_004936718 | 55879 | 59547 | Squirrel | 31 | description | gene, protein-coding, MODEL [RefSeq] |
| 12675470 | Sp7 | Sp7 transcription factor | ENCODES a protein that exhibits DEAD/H-box RNA helicase binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN cellular response to parathyroid hormone stimulus (ortholog); cellular response to zinc ion star ='font-weight:700;'>starvation (ortholog); osteoblast differentiation (ortholog); ASSOCIATED WITH aortic valve stenosis (ortholog); BCARD syndrome (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred) | NW_004936512 | 10610542 | 10613335 | Squirrel | 42 | description | gene, protein-coding, MODEL [RefSeq] |
| 12522113 | Srebf2 | sterol regulatory element binding transcription factor 2 | ENCODES a protein that exhibits C-8 sterol isomerase activity (ortholog); chromatin binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN cellular response to low-density lipoprotein particle stimulus (ortholog); cellular response to star rvation (ortholog); cholesterol homeostasis (ortholog); PARTICIPATES IN altered p53 signaling pathway; sterol regulatory element-binding protein signaling pathway; ASSOCIATED WITH alcohol use disorder (ortholog); atherosclerosis (ortholog); Breast Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); dendrite (ortholog); endoplasmic reticulum (ortholog) | NW_004936492 | 115923 | 174614 | Squirrel | 103 | description | gene, protein-coding, MODEL [RefSeq] |
| 12694349 | Stk24 | serine/threonine kinase 24 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); metal ion binding (inferred); INVOLVED IN cellular response to oxidative stress (ortholog); cellular response to starvation (ortholog); execution phase of apoptosis (ortholog); F OUND IN cytosol (ortholog); FAR/SIN/STRIPAK complex (ortholog); Golgi membrane (ortholog) | NW_004936472 | 11788439 | 11888703 | Squirrel | 36 | description | gene, protein-coding, MODEL [RefSeq] |
| 12590948 | Tbl2 | transducin beta like 2 | ENCODES a protein that exhibits phosphoprotein binding (inferred); protein kinase binding (inferred); translation initiation factor binding (inferred); INVOLVED IN cellular response to glucose starvation (inferred); cellular response to hypoxia (inferred); endop lasmic reticulum unfolded protein response (inferred); ASSOCIATED WITH COVID-19 (ortholog); microcephaly (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cytosol (inferred); endoplasmic reticulum (inferred) | NW_004936543 | 2825990 | 2833908 | Squirrel | 14 | description | gene, protein-coding, MODEL [RefSeq] |
| 12472881 | Tcf7l2 | transcription factor 7 like 2 | ENCODES a protein that exhibits chromatin binding (ortholog); promoter-specific chromatin binding (ortholog); INVOLVED IN bone mineralization (ortholog); cellular response to starvation (ortholog); embryonic digestive tract morphogenesis (ortholog); PARTICIPATES IN altered Wnt signaling, canonical pathway; pancreatic cancer pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Animal Disease Models (ortholog); autistic disorder (ortholog); FOUND IN cytosol (ortholog); transcription regulator complex (ortholog) | NW_004936486 | 3473877 | 3660565 | Squirrel | 158 | description | gene, protein-coding, MODEL [RefSeq] |
| 12511755 | Tnfrsf11a | TNF receptor superfamily member 11a | ENCODES a protein that exhibits cytokine binding (inferred); transmembrane signaling receptor activity (inferred); tumor necrosis factor receptor activity (inferred); INVOLVED IN cellular response to zinc ion starvation (ortholog); lymph node development (orthol og); mammary gland alveolus development (ortholog); ASSOCIATED WITH Alveolar Bone Loss (ortholog); autosomal recessive osteopetrosis 7 (ortholog); B-Cell Chronic Lymphocytic Leukemia (ortholog); FOUND IN cell surface (inferred); external side of plasma membrane (inferred); membrane (inferred) | NW_004936497 | 2944841 | 2986113 | Squirrel | 75 | description | gene, protein-coding, MODEL [RefSeq] |
| 12536985 | Tnrc6a | trinucleotide repeat containing adaptor 6A | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN cellular response to starvation (ortholog); endoderm development (ortholog); PARTICIPATES IN microRNA pathway; ASSOCIATED WITH familial adult myoclonic epilepsy 6 (ortholog); Myoclonic Epilepsies (ortholog); FOUND IN P-body (ortholog) | NW_004936501 | 9016844 | 9192946 | Squirrel | 36 | description | gene, protein-coding, MODEL [RefSeq] |
| 12482121 | Tp53 | tumor protein p53 | ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); MDM2/MDM4 family protein binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to glucose starvation (ortholog); cellular response to heat (ortholog); cellul ar response to hypoxia (ortholog); PARTICIPATES IN altered p53 signaling pathway; endometrial cancer pathway; non-small cell lung carcinoma pathway; ASSOCIATED WITH Acute Erythroleukemia (ortholog); acute kidney failure (ortholog); acute lymphoblastic leukemia (ortholog); FOUND IN chromatin (ortholog); nucleus (ortholog); RNA polymerase II transcription regulator complex (ortholog) | NW_004936595 | 919807 | 935367 | Squirrel | 1148 | description | gene, protein-coding, MODEL [RefSeq] |
| 12737486 | Ucp2 | uncoupling protein 2 | ENCODES a protein that exhibits antiporter activity (inferred); chloride transmembrane transporter activity (inferred); GDP binding (inferred); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to glucose stimulus (ortholog); c ellular response to hormone stimulus (ortholog); PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH Acute Liver Failure (ortholog); Animal Mammary Neoplasms (ortholog); Brain Injuries (ortholog); FOUND IN membrane (inferred); mitochondrial inner membrane (inferred); mitochondrial membrane (inferred) | NW_004936498 | 3059700 | 3066112 | Squirrel | 106 | description | gene, protein-coding, MODEL [RefSeq] |
| 12708711 | Upp1 | uridine phosphorylase 1 | ENCODES a protein that exhibits thymidine phosphorylase activity (ortholog); INVOLVED IN cellular response to glucose starvation (ortholog); dTMP catabolic process (ortholog); pyrimidine nucleotide metabolic process (ortholog); ASSOCIATED WITH allergic contact d ermatitis (ortholog); long QT syndrome (ortholog); middle cerebral artery infarction (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred) | NW_004936478 | 22508602 | 22531604 | Squirrel | 38 | description | gene, protein-coding, MODEL [RefSeq] |
| 12640671 | Vldlr | very low density lipoprotein receptor | ENCODES a protein that exhibits apolipoprotein binding (inferred); calcium ion binding (inferred); calcium-dependent protein binding (inferred); INVOLVED IN cellular response to glucose starvation (ortholog); cellular response to hypoxia (ortholog); cellular res ponse to insulin stimulus (ortholog); PARTICIPATES IN altered Reelin signaling pathway; Reelin signaling pathway; ASSOCIATED WITH age related macular degeneration 1 (ortholog); Alzheimer's disease (ortholog); amenorrhea (ortholog); FOUND IN apical part of cell (ortholog); cell surface (ortholog); perinuclear region of cytoplasm (ortholog) | NW_004936503 | 2407040 | 2440366 | Squirrel | 96 | description | gene, protein-coding, MODEL [RefSeq] |
| 12733798 | Wdr45 | WD repeat domain 45 | ENCODES a protein that exhibits lipid binding (inferred); phosphatidylinositol phosphate binding (inferred); phosphatidylinositol-3-phosphate binding (inferred); INVOLVED IN autophagosome assembly (inferred); autophagy (inferred); cellular response to starvation (inferred); ASSOCIATED WITH autistic disorder (ortholog); CEREBRAL-CEREBELLAR-COLOBOMA SYNDROME, X-LINKED (ortholog); Developmental Disabilities (ortholog); FOUND IN phagophore assembly site (inferred) | NW_004936721 | 975113 | 981149 | Squirrel | 28 | description | gene, protein-coding, MODEL [RefSeq] |
| 12684573 | Wdr45b | WD repeat domain 45B | ENCODES a protein that exhibits lipid binding (inferred); phosphatidylinositol-3,5-bisphosphate binding (inferred); phosphatidylinositol-3-phosphate binding (inferred); INVOLVED IN autophagosome assembly (inferred); autophagy (inferred); cellular response to star >vation (inferred); ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); Neurodevelopmental Disorder with Spastic Quadriplegia and Brain Abnormalities with or without Seizures (ortholog); FOUND IN cytosol (inferred); lysosome (inferred); phagophore assembly site (inferred) | NW_004936923 | 173515 | 192616 | Squirrel | 19 | description | gene, protein-coding, MODEL [RefSeq] |
| 12570764 | Wipi1 | WD repeat domain, phosphoinositide interacting 1 | ENCODES a protein that exhibits lipid binding (inferred); nuclear androgen receptor binding (inferred); nuclear estrogen receptor binding (inferred); INVOLVED IN autophagosome assembly (inferred); autophagy (inferred); cellular response to starvation (inferred); ASSOCIATED WITH cholestasis (ortholog); lipid storage disease (ortholog); FOUND IN autophagosome membrane (inferred); cytoplasm (inferred); cytosol (inferred) | NW_004936541 | 7782836 | 7812142 | Squirrel | 26 | description | gene, protein-coding, MODEL [RefSeq] |
| 12609210 | Wnt2b | Wnt family member 2B | ENCODES a protein that exhibits cytokine activity (inferred); frizzled binding (inferred); signaling receptor binding (inferred); INVOLVED IN canonical Wnt signaling pathway (ortholog); cellular response to starvation (ortholog); lung induction (ortholog); PARTI CIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH Diarrhea 9 (ortholog); endodermal sinus tumor (ortholog); Failure to Thrive (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | NW_004936690 | 1077538 | 1094005 | Squirrel | 33 | description | gene, protein-coding, MODEL [RefSeq] |
| 12721742 | Wrn | WRN RecQ like helicase | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN cellular response to starvation (ortholog); determination of adult lifespan (ortholog); DNA metabolic process (ortholog); ASSOCIATED WITH breast cancer (ortholog); coronary artery disease (ortholog); diffuse scleroderma (ortholog); FOUND IN centrosome (inferred); chromosome (inferred); chromosome, telomeric region (inferred) | NW_004936792 | 862659 | 1005065 | Squirrel | 133 | description | gene, protein-coding, MODEL [RefSeq] |
| 12525311 | Yars1 | tyrosyl-tRNA synthetase 1 | ENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); ATP binding (inferred); ligase activity (inferred); INVOLVED IN response to starvation (inferred); response to stress (inferred); translation (inferred); PARTICIPATES IN phenylketonuria p athway; tyrosinemia type II pathway; tyrosinemia type III pathway; ASSOCIATED WITH Agenesis of Corpus Callosum (ortholog); Charcot-Marie-Tooth disease (ortholog); Charcot-Marie-Tooth disease dominant intermediate C (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nuclear body (inferred) | NW_004936474 | 15691838 | 15721308 | Squirrel | 48 | description | gene, protein-coding, MODEL [RefSeq] |
| 12539535 | Yme1l1 | YME1 like 1 ATPase | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent peptidase activity (inferred); INVOLVED IN cell population proliferation (inferred); cellular response to starvation (inferred); mitochondrial protein catab olic process (inferred); ASSOCIATED WITH 3-methylglutaconic aciduria (ortholog); dilated cardiomyopathy (ortholog); fundus dystrophy (ortholog); FOUND IN membrane (inferred); mitochondrial inner membrane (inferred); mitochondrial membrane (inferred) | NW_004936484 | 2306937 | 2352671 | Squirrel | 44 | description | gene, protein-coding, MODEL [RefSeq] |
| 12526180 | Ywhaz | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); identical protein binding (ortholog); phosphoserine residue binding (ortholog); INVOLVED IN angiogenesis (ortholog); cellular response to glucose starvation (ortholog); ERK1 and ERK2 cascade (ortholog); PARTICIPATES IN granulocyte-macrophage colony-stimulating factor signaling pathway; histone modification pathway; insulin responsive facilitative sugar transporter mediated glucose transport pathway; ASSOCIATED WITH absence epilepsy (ortholog); Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); FOUND IN cell leading edge (ortholog); cytoplasm (ortholog); cytosol (ortholog) | NW_004936470 | 42444671 | 42470548 | Squirrel | 182 | description | gene, protein-coding, MODEL [RefSeq] |
| 12576483 | Zfyve1 | zinc finger FYVE-type containing 1 | ENCODES a protein that exhibits 1-phosphatidylinositol binding (inferred); metal ion binding (inferred); phosphatidylinositol-3,4,5-trisphosphate binding (inferred); INVOLVED IN cellular response to starvation (inferred); host-mediated activation of viral genome replication (inferred); lipid droplet formation (inferred); FOUND IN autophagosome (inferred); endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred) | NW_004936488 | 2304521 | 2364472 | Squirrel | 45 | description | gene, protein-coding, MODEL [RefSeq] |