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Gene: Eif2b1 (eukaryotic translation initiation factor 2B subunit alpha) Ictidomys tridecemlineatus

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Symbol:

Eif2b1

Name:

eukaryotic translation initiation factor 2B subunit alpha

RGD ID:

12633094

Description:

ENCODES a protein that exhibits GDP binding (ortholog); GTP binding (ortholog); translation initiation factor activity (ortholog); INVOLVED IN negative regulation of guanyl-nucleotide exchange factor activity (ortholog); response to amino acid starvation (ortholog); response to glucose (ortholog); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH Animal Disease Models (ortholog); epilepsy (ortholog); genetic disease (ortholog); FOUND IN eukaryotic translation initiation factor 2 complex (ortholog); eukaryotic translation initiation factor 2B complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

translation initiation factor eIF-2B subunit alpha

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	158,273,558 - 158,283,344 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936558	1,196,068 - 1,205,867 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936558	1,196,111 - 1,205,321 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Eif2b1	Squirrel	epilepsy		ISO	EIF2B1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Epilepsy	ClinVar
Eif2b1	Squirrel	genetic disease		ISO	EIF2B1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:25741868 and PMID:28492532
Eif2b1	Squirrel	Joubert syndrome 1		ISO	EIF2B1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Familial aplasia of the vermis	ClinVar	PMID:28492532
Eif2b1	Squirrel	Leukoencephalopathies		ISO	EIF2B1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: CACH/VWM syndrome	ClinVar	PMID:11835386 more ...
Eif2b1	Squirrel	leukoencephalopathy with vanishing white matter		ISO	EIF2B1 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:11835386 more ...
Eif2b1	Squirrel	leukoencephalopathy with vanishing white matter 1		ISO	EIF2B1 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:11835386 more ...
Eif2b1	Squirrel	leukoencephalopathy with vanishing white matter 5		ISO	EIF2B1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Cree leukoencephalopathy	ClinVar	PMID:11835386 more ...
Eif2b1	Squirrel	microcephaly		ISO	EIF2B1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Microcephaly	ClinVar	PMID:25741868
Eif2b1	Squirrel	short chain acyl-CoA dehydrogenase deficiency		ISO	EIF2B1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Deficiency of butyryl-CoA dehydrogenase	ClinVar	PMID:28492532
Eif2b1	Squirrel	visual epilepsy		ISO	EIF2B1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Focal seizures	ClinVar

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Eif2b1	Squirrel	Animal Disease Models		ISO	EIF2B1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:27602772
Eif2b1	Squirrel	lung adenocarcinoma		ISO	EIF2B1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:27602772

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Eif2b1	Squirrel	leukoencephalopathy with vanishing white matter 1		ISO	EIF2B1 (Homo sapiens)	7240710		OMIM

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Eif2b1	Squirrel	cytoplasmic translational initiation	involved_in	IEA	UniProtKB:Q14232 and ensembl:ENSP00000416250	150520179		Ensembl	GO_REF:0000107
Eif2b1	Squirrel	negative regulation of guanyl-nucleotide exchange factor activity		ISO	Eif2b1 (Rattus norvegicus)	9068941		RGD	PMID:9582312 and REF_RGD_ID:1581075
Eif2b1	Squirrel	oligodendrocyte development	involved_in	IEA	UniProtKB:Q14232 and ensembl:ENSP00000416250	150520179		Ensembl	GO_REF:0000107
Eif2b1	Squirrel	response to amino acid starvation		ISO	Eif2b1 (Rattus norvegicus)	9068941		RGD	PMID:11500297 and REF_RGD_ID:1581065
Eif2b1	Squirrel	response to glucose	involved_in	ISO	Eif2b1 (Rattus norvegicus)	9068941	PMID:8567668	UniProt	PMID:8567668 and REF_RGD_ID:8554699
Eif2b1	Squirrel	response to heat	involved_in	ISO	Eif2b1 (Rattus norvegicus)	9068941	PMID:9341116	UniProt	PMID:9341116 and REF_RGD_ID:8554311
Eif2b1	Squirrel	response to peptide hormone	involved_in	ISO	Eif2b1 (Rattus norvegicus)	9068941	PMID:8430778	UniProt	PMID:8430778 and REF_RGD_ID:8553606
Eif2b1	Squirrel	T cell receptor signaling pathway	involved_in	IEA	UniProtKB:Q14232 and ensembl:ENSP00000416250	150520179		Ensembl	GO_REF:0000107
Eif2b1	Squirrel	translation		ISO	Eif2b1 (Rattus norvegicus)	9068941		RGD	PMID:3818593 and REF_RGD_ID:1581069
Eif2b1	Squirrel	translation	involved_in	IEA	UniProtKB-KW:KW-0648	150520179		UniProt	GO_REF:0000043
Eif2b1	Squirrel	translational initiation		ISO	Eif2b1 (Rattus norvegicus)	9068941		RGD	PMID:3818593 and REF_RGD_ID:1581069
Eif2b1	Squirrel	translational initiation	involved_in	IEA	UniProtKB-KW:KW-0396	150520179		UniProt	GO_REF:0000043
Eif2b1	Squirrel	translational initiation	involved_in	IEA	UniProtKB:Q14232 and ensembl:ENSP00000416250	150520179		Ensembl	GO_REF:0000107
Eif2b1	Squirrel	translational initiation	involved_in	IEA	PANTHER:PTN000028074	150520179		TreeGrafter	GO_REF:0000118

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Eif2b1	Squirrel	cytoplasm	located_in	IEA	UniProtKB:Q14232 and ensembl:ENSP00000416250	150520179		Ensembl	GO_REF:0000107
Eif2b1	Squirrel	cytosol	located_in	IEA	UniProtKB-SubCell:SL-0091	150520179		UniProt	GO_REF:0000044
Eif2b1	Squirrel	eukaryotic translation initiation factor 2 complex		ISO	Eif2b1 (Rattus norvegicus)	9068941		RGD	PMID:3818593 and REF_RGD_ID:1581069
Eif2b1	Squirrel	eukaryotic translation initiation factor 2B complex		ISO	Eif2b1 (Rattus norvegicus)	9068941		RGD	PMID:9631509 and REF_RGD_ID:11041878
Eif2b1	Squirrel	eukaryotic translation initiation factor 2B complex	part_of	IEA	UniProtKB:Q14232 and ensembl:ENSP00000416250	150520179		Ensembl	GO_REF:0000107
Eif2b1	Squirrel	eukaryotic translation initiation factor 2B complex	part_of	IEA	PANTHER:PTN000028074	150520179		TreeGrafter	GO_REF:0000118
Eif2b1	Squirrel	membrane	located_in	IEA	UniProtKB:Q14232 and ensembl:ENSP00000416250	150520179		Ensembl	GO_REF:0000107
Eif2b1	Squirrel	plasma membrane	located_in	IEA	UniProtKB:Q14232 and ensembl:ENSP00000416250	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Eif2b1	Squirrel	GDP binding		ISO	Eif2b1 (Rattus norvegicus)	9068941		RGD	PMID:3818593 and REF_RGD_ID:1581069
Eif2b1	Squirrel	GTP binding		ISO	Eif2b1 (Rattus norvegicus)	9068941		RGD	PMID:3818593 and REF_RGD_ID:1581069
Eif2b1	Squirrel	guanyl-nucleotide exchange factor activity	enables	IEA	PANTHER:PTN000028074	150520179		TreeGrafter	GO_REF:0000118
Eif2b1	Squirrel	guanyl-nucleotide exchange factor activity	contributes_to	IEA	UniProtKB:Q14232 and ensembl:ENSP00000416250	150520179		Ensembl	GO_REF:0000107
Eif2b1	Squirrel	identical protein binding	enables	IEA	UniProtKB:Q14232 and ensembl:ENSP00000416250	150520179		Ensembl	GO_REF:0000107
Eif2b1	Squirrel	protein binding	enables	ISO	PR:P45481	9068941	PMID:15752756	MGI	PMID:15752756
Eif2b1	Squirrel	protein binding	enables	ISO	UniProtKB:Q7KZS0 more ...	9068941	PMID:32296183	IntAct	PMID:32296183
Eif2b1	Squirrel	protein binding	enables	ISO	UniProtKB:Q7Z3Z2 more ...	9068941	PMID:25416956 and PMID:31515488	IntAct	PMID:25416956 and PMID:31515488
Eif2b1	Squirrel	protein binding	enables	ISO	UniProtKB:Q9H8Y8	9068941	PMID:29892012	IntAct	PMID:29892012
Eif2b1	Squirrel	protein binding	enables	ISO	UniProtKB:P30545 and UniProtKB:Q01338	9068941	PMID:9235896	IntAct	PMID:9235896
Eif2b1	Squirrel	translation initiation factor activity	enables	IEA	PANTHER:PTN000028074	150520179		TreeGrafter	GO_REF:0000118
Eif2b1	Squirrel	translation initiation factor activity	contributes_to	IEA	UniProtKB:Q14232 and ensembl:ENSP00000416250	150520179		Ensembl	GO_REF:0000107
Eif2b1	Squirrel	translation initiation factor activity	enables	IEA	UniProtKB-KW:KW-0396	150520179		UniProt	GO_REF:0000043
Eif2b1	Squirrel	translation initiation factor activity		ISO	Eif2b1 (Rattus norvegicus)	9068941		RGD	PMID:3818593 more ...

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Eif2b1	Squirrel	translation initiation pathway		ISO	EIF2B1 (Homo sapiens)	9068941		RGD	PMID:22815232 and REF_RGD_ID:10044017

PMID:30032202

Eif2b1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	158,273,558 - 158,283,344 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936558	1,196,068 - 1,205,867 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936558	1,196,111 - 1,205,321 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EIF2B1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	123,620,406 - 123,633,686 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	123,620,406 - 123,633,766 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	124,104,953 - 124,118,233 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	122,671,523 - 122,684,200 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	122,630,458 - 122,642,993	NCBI
Celera	12	123,702,006 - 123,714,759 (-)	NCBI		Celera
Cytogenetic Map	12	q24.31	NCBI
HuRef	12	121,066,914 - 121,079,569 (-)	NCBI		HuRef
CHM1_1	12	123,926,519 - 123,939,272 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	123,619,272 - 123,632,550 (-)	NCBI		T2T-CHM13v2.0

Eif2b1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	124,708,277 - 124,717,194 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	124,708,276 - 124,717,194 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	124,570,214 - 124,579,131 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	124,570,213 - 124,579,131 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	125,020,223 - 125,029,066 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	124,831,271 - 124,839,665 (-)	NCBI		MGSCv36	mm8
Celera	5	121,646,913 - 121,655,757 (-)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	63.67	NCBI

Eif2b1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	37,686,149 - 37,694,830 (+)	NCBI		GRCr8
mRatBN7.2	12	32,025,593 - 32,033,848 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	32,025,557 - 32,046,601 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	33,203,928 - 33,212,772 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	33,815,249 - 33,824,093 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	32,867,116 - 32,875,960 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	37,444,136 - 37,452,391 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	37,444,072 - 37,465,398 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	39,315,146 - 39,323,401 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	33,138,323 - 33,146,596 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	12	33,715,011 - 33,723,266 (+)	NCBI		Celera
Cytogenetic Map	12	q15	NCBI

Eif2b1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955482	5,380,121 - 5,388,588 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955482	5,380,121 - 5,388,588 (+)	NCBI	ChiLan1.0	ChiLan1.0

EIF2B1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	131,695,932 - 131,708,303 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	131,692,309 - 131,704,680 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	121,206,380 - 121,218,749 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	125,433,227 - 125,445,418 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	125,433,227 - 125,446,665 (-)	Ensembl	panpan1.1		panPan2

EIF2B1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	6,011,280 - 6,022,562 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	6,011,301 - 6,022,518 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	6,174,138 - 6,185,441 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	6,261,358 - 6,272,647 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	6,261,376 - 6,272,698 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	6,194,833 - 6,206,124 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	6,287,198 - 6,298,495 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	6,240,405 - 6,251,707 (+)	NCBI		UU_Cfam_GSD_1.0

EIF2B1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	29,332,233 - 29,367,918 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	29,355,497 - 29,367,918 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	31,047,776 - 31,060,210 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EIF2B1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	118,949,674 - 118,961,913 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	118,950,409 - 118,961,687 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	126,313,981 - 126,326,188 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Eif2b1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	23,414,077 - 23,421,074 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624747	23,413,045 - 23,422,227 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_005329552	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000006159 ⟹ ENSSTOP00000005510

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936558	1,196,068 - 1,205,867 (+)	Ensembl

RefSeq Acc Id:

XM_005329552 ⟹ XP_005329609

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	158,273,558 - 158,283,344 (-)	NCBI
SpeTri2.0	NW_004936558	1,196,111 - 1,205,321 (+)	NCBI

Sequence:

show sequence

TGGGGTGCGCCGCGCGCTGTCAGCTTGTGACTCGGCCGGCTCAGTCGCGGGACTCGCTAGCAGCGAGCGACTCTGGGGCCCCAGCTCTCCGCGGTCCAGAGGCACCATGGACGACAGGGAATTAATTG
AATACTTCAAATCTCAGATGAAAGAAGATCCTGACATGGCCTCAGCAGTGGCTGCCATCCGGACTTTGCTGGAGTTCCTGAAGAGAGATAAAGGGGAGACAATCCAGGGCCTGAGAGCAAATCTCACC
AGCGCCATAGAAACCCTGTGTGGCGTGGACTCCTCTGTGGCAGTGTCCTCTGGTGGGGAGCTCTTCCTTCGTTTCATCAGCCTTACCTCCCTGGAGTACTCGGATTACTCTAAATGTAAAAAGATCAT
GATTGAGCGAGGAGAGCTTTTTCTCAGGAGAATATCCCTGTCGAGAAATAAAATTGCTGATCTATGCCATACTTTCATCAAAGATGGGGCGAGAATATTGACTCACGCCTACTCCAGAGTGGTCCTGA
GAGTACTTGAAGCAGCTGTGGCAGCCAAGAAGCGCTTTAGTGTGTACATTACAGAGTCGCAGCCTGATCTGGCGGGTAAGAAAATGGCCAAAGCGCTCTCTCACCTCAACGTCCCAGTCACCGTGGTG
CTGGATGCTGCTGTTGGCTACATCATGGAGAAAGTAGACCTCGTCATAGTCGGCGCTGAAGGAGTCGTTGAAAACGGAGGGATTATTAACAAGATTGGGAGCCACCAGATGGCCGTGTGTGCCAAGGC
ACAGAACAAGCCCTTCTATGTGGTTGCAGAAAGCTTCAAGTTTGTGCGGCTATTCCCACTAAACCAGCAAGACGTCCCAGATAAATTTAAGTACAAGGCAGATACTCTGAAGTCTGCACAGACTGGAC
AGGACCTGAGAGAGGAGCACCCATGGGTGGACTACACCTCCCCTTCGTTAATCACCCTGCTATTCACAGACCTGGGTGTGCTCACACCCTCAGCAGTCAGTGACGAACTCATCAAGCTTTATCTATAA
CCATCGGTCTTCCCGGTGTCCAGTGTACCTGCCTGGGGCAAGGTGGGCAGCCTCTCAACCCCTGTGAGCCAAGCCAAAAGGAATCATTCTATGGAAGACCCGTGGACTGTGGATATAAATTACATGTC
TTGGAGGATC

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Protein RefSeqs	XP_005329609	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000005510.2
GenBank Protein	KAG3279163	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005329609 ⟸ XM_005329552

- UniProtKB:

I3M7D1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDDRELIEYFKSQMKEDPDMASAVAAIRTLLEFLKRDKGETIQGLRANLTSAIETLCGVDSSVAVSSGGELFLRFISLTSLEYSDYSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGARILTH
AYSRVVLRVLEAAVAAKKRFSVYITESQPDLAGKKMAKALSHLNVPVTVVLDAAVGYIMEKVDLVIVGAEGVVENGGIINKIGSHQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADT
LKSAQTGQDLREEHPWVDYTSPSLITLLFTDLGVLTPSAVSDELIKLYL

hide sequence

Ensembl Acc Id:

ENSSTOP00000005510 ⟸ ENSSTOT00000006159

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000006157	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000006159.3	UniProtKB/TrEMBL
Gene3D-CATH	1.20.120.1070	UniProtKB/TrEMBL
	Translation initiation factor eif-2b, domain 2	UniProtKB/TrEMBL
InterPro	eIF2B_alpha/beta/delta	UniProtKB/TrEMBL
	elF-2B_alpha_N	UniProtKB/TrEMBL
	IF-2B-related	UniProtKB/TrEMBL
	IF_2B-like_C	UniProtKB/TrEMBL
	NagB/RpiA_transferase-like	UniProtKB/TrEMBL
NCBI Gene	Eif2b1	ENTREZGENE
PANTHER	TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA	UniProtKB/TrEMBL
	TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA	UniProtKB/TrEMBL
Pfam	IF-2B	UniProtKB/TrEMBL
Superfamily-SCOP	SSF100950	UniProtKB/TrEMBL
UniProt	I3M7D1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations