Ehmt2 (euchromatic histone lysine methyltransferase 2) - Rat Genome Database

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Gene: Ehmt2 (euchromatic histone lysine methyltransferase 2) Ictidomys tridecemlineatus
Analyze
Symbol: Ehmt2
Name: euchromatic histone lysine methyltransferase 2
RGD ID: 12503130
Description: ENCODES a protein that exhibits C2H2 zinc finger domain binding (inferred); histone H3 methyltransferase activity (inferred); histone H3K27 methyltransferase activity (inferred); INVOLVED IN behavioral response to cocaine (ortholog); cellular response to cocaine (ortholog); cellular response to starvation (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); acute myeloid leukemia (ortholog); alopecia areata (ortholog); FOUND IN nucleolus (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: histone-lysine N-methyltransferase EHMT2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494635,898,050 - 35,912,895 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367271,648,448 - 1,663,455 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367271,648,451 - 1,663,294 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IEA)
chromosome  (IEA)
nuclear speck  (IEA)
nucleolus  (ISO)
nucleoplasm  (IEA)
nucleus  (IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ehmt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494635,898,050 - 35,912,895 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367271,648,448 - 1,663,455 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367271,648,451 - 1,663,294 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EHMT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38631,879,759 - 31,897,698 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl631,879,759 - 31,897,698 (-)EnsemblGRCh38hg38GRCh38
GRCh37631,847,536 - 31,865,475 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36631,955,515 - 31,973,443 (-)NCBINCBI36Build 36hg18NCBI36
Celera633,446,117 - 33,464,048 (-)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef631,633,340 - 31,651,520 (-)NCBIHuRef
CHM1_1631,849,677 - 31,867,605 (-)NCBICHM1_1
T2T-CHM13v2.0631,732,994 - 31,750,940 (-)NCBIT2T-CHM13v2.0
Ehmt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391735,117,427 - 35,133,049 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1735,117,445 - 35,133,028 (+)EnsemblGRCm39 Ensembl
GRCm381734,898,463 - 34,914,073 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,898,469 - 34,914,052 (+)EnsemblGRCm38mm10GRCm38
MGSCv371735,035,444 - 35,050,992 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361734,506,555 - 34,522,103 (+)NCBIMGSCv36mm8
Celera1737,993,807 - 38,010,279 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.45NCBI
Ehmt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8203,924,263 - 3,941,238 (-)NCBIGRCr8
mRatBN7.2203,919,623 - 3,936,751 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl203,919,624 - 3,941,547 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,619,529 - 4,635,983 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0203,981,271 - 3,997,725 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,518,475 - 4,534,917 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0204,576,033 - 4,592,980 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,576,057 - 4,592,980 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,656,049 - 6,672,967 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,021,679 - 4,033,709 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1204,021,905 - 4,033,936 (-)NCBI
Celera204,093,733 - 4,109,892 (+)NCBICelera
Cytogenetic Map20p12NCBI
Ehmt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955437396,742 - 411,144 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955437396,736 - 411,144 (-)NCBIChiLan1.0ChiLan1.0
EHMT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2546,358,802 - 46,376,755 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1642,320,293 - 42,338,260 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0631,542,946 - 31,560,894 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,429,265 - 32,446,860 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,429,271 - 32,451,844 (-)Ensemblpanpan1.1panPan2
EHMT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,341,202 - 1,354,602 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,341,191 - 1,354,584 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,476,470 - 1,489,841 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,483,381 - 1,496,739 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,483,381 - 1,497,535 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1121,341,088 - 1,354,451 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,409,030 - 1,422,401 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,474,485 - 1,487,852 (-)NCBIUU_Cfam_GSD_1.0
EHMT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl723,977,683 - 23,993,478 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1723,977,683 - 23,992,673 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2727,818,555 - 27,834,344 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EHMT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11740,123,935 - 40,141,942 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1740,124,640 - 40,141,616 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604431,794,809 - 31,812,826 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ehmt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475424,354,284 - 24,368,638 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475424,354,271 - 24,368,319 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000028473   ⟹   ENSSTOP00000016647
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049367271,648,448 - 1,663,455 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000036881   ⟹   ENSSTOP00000030529
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049367271,648,448 - 1,663,455 (+)Ensembl
RefSeq Acc Id: XM_013364615   ⟹   XP_013220069
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494635,898,050 - 35,912,895 (-)NCBI
SpeTri2.0NW_0049367271,648,451 - 1,663,294 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040282395   ⟹   XP_040138329
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494635,898,417 - 35,912,890 (-)NCBI
RefSeq Acc Id: XR_005732708
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494635,898,050 - 35,912,890 (-)NCBI
RefSeq Acc Id: XR_005732709
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494635,898,050 - 35,912,890 (-)NCBI
RefSeq Acc Id: XR_005732710
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494635,898,050 - 35,912,890 (-)NCBI
RefSeq Acc Id: XR_005732711
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494635,899,168 - 35,912,890 (-)NCBI
Protein Sequences
Protein RefSeqs XP_013220069 (Get FASTA)   NCBI Sequence Viewer  
  XP_040138329 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000016647.2
  ENSSTOP00000030529.1
GenBank Protein KAG3289133 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_013220069   ⟸   XM_013364615
- Peptide Label: isoform X1
- UniProtKB: I3MX02 (UniProtKB/TrEMBL),   A0A287DAG9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040138329   ⟸   XM_040282395
- Peptide Label: isoform X2
- UniProtKB: A0A287DAG9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSSTOP00000030529   ⟸   ENSSTOT00000036881
Ensembl Acc Id: ENSSTOP00000016647   ⟸   ENSSTOT00000028473
Protein Domains
Pre-SET   SET


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000020917 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000028473.2 UniProtKB/TrEMBL
  ENSSTOT00000036881.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
  2.170.270.10 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  EHMT1/EHMT2 UniProtKB/TrEMBL
  EHMT2 UniProtKB/TrEMBL
  EHMT_ZBD UniProtKB/TrEMBL
  Pre-SET_dom UniProtKB/TrEMBL
  SET_dom UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/TrEMBL
NCBI Gene Ehmt2 ENTREZGENE
PANTHER PTHR46307 UniProtKB/TrEMBL
  PTHR46307:SF1 UniProtKB/TrEMBL
Pfam Ank UniProtKB/TrEMBL
  Ank_2 UniProtKB/TrEMBL
  EHMT1-2_CRR UniProtKB/TrEMBL
  Pre-SET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
PRINTS ANKYRIN UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
  PRE_SET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
  PreSET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
  SSF82199 UniProtKB/TrEMBL
UniProt A0A287DAG9 ENTREZGENE, UniProtKB/TrEMBL
  I3MX02 ENTREZGENE, UniProtKB/TrEMBL