Gpt2 (glutamic--pyruvic transaminase 2) - Rat Genome Database

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Gene: Gpt2 (glutamic--pyruvic transaminase 2) Ictidomys tridecemlineatus
Analyze
Symbol: Gpt2
Name: glutamic--pyruvic transaminase 2
RGD ID: 12631688
Description: ENCODES a protein that exhibits catalytic activity (inferred); L-alanine:2-oxoglutarate aminotransferase activity (inferred); pyridoxal phosphate binding (inferred); INVOLVED IN cellular response to insulin stimulus (ortholog); positive regulation of gluconeogenesis (ortholog); response to starvation (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Chronic Hepatitis C (ortholog); fatty liver disease (ortholog); FOUND IN extracellular space (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: alanine aminotransferase 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934959,289,309 - 59,326,531 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936475262,920 - 297,459 (+)EnsemblSpeTri2.0
SpeTri2.0NW_004936475262,558 - 299,766 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
Gpt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934959,289,309 - 59,326,531 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936475262,920 - 297,459 (+)EnsemblSpeTri2.0
SpeTri2.0NW_004936475262,558 - 299,766 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381646,884,362 - 46,931,289 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1646,884,362 - 46,931,289 (+)EnsemblGRCh38hg38GRCh38
GRCh371646,918,274 - 46,965,201 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361645,475,809 - 45,522,699 (+)NCBINCBI36Build 36hg18NCBI36
Build 341645,475,808 - 45,522,699NCBI
Celera1631,426,465 - 31,473,333 (+)NCBICelera
Cytogenetic Map16q11.2NCBI
HuRef1632,808,713 - 32,855,581 (+)NCBIHuRef
CHM1_11648,325,402 - 48,372,269 (+)NCBICHM1_1
T2T-CHM13v2.01652,681,247 - 52,728,152 (+)NCBIT2T-CHM13v2.0
Gpt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39886,219,090 - 86,255,531 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl886,219,205 - 86,254,189 (+)EnsemblGRCm39 Ensembl
GRCm38885,492,576 - 85,528,902 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl885,492,576 - 85,527,560 (+)EnsemblGRCm38mm10GRCm38
MGSCv37888,016,516 - 88,051,457 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36888,382,722 - 88,417,663 (+)NCBIMGSCv36mm8
Celera889,788,449 - 89,823,364 (+)NCBICelera
Cytogenetic Map8C3NCBI
Gpt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21921,526,800 - 21,561,314 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1921,517,621 - 21,560,610 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1923,215,489 - 23,248,192 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01928,410,012 - 28,442,715 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01931,372,800 - 31,405,503 (-)NCBIRnor_WKY
Rnor_6.01922,599,003 - 22,633,529 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1922,590,881 - 22,632,071 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01933,605,445 - 33,644,015 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41922,884,586 - 22,915,553 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11922,889,411 - 22,920,379 (-)NCBI
Celera1921,389,431 - 21,420,291 (-)NCBICelera
Cytogenetic Map19p11NCBI
Gpt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554748,250,759 - 8,285,227 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554748,248,622 - 8,285,449 (-)NCBIChiLan1.0ChiLan1.0
GPT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11646,040,439 - 46,086,840 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1646,040,439 - 46,086,840 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01627,150,159 - 27,197,006 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
GPT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1158,238,295 - 8,250,789 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha158,390,680 - 8,414,551 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0158,352,399 - 8,376,276 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1158,180,716 - 8,204,556 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0158,261,783 - 8,285,636 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0158,277,131 - 8,301,012 (-)NCBIUU_Cfam_GSD_1.0
GPT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl637,625,436 - 37,669,663 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1637,625,428 - 37,669,695 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2632,865,392 - 32,909,952 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GPT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1532,743,850 - 32,791,299 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl532,744,065 - 32,791,479 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604743,782,468 - 43,830,157 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gpt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624914459,701 - 501,765 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624914460,240 - 501,087 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000014856   ⟹   ENSSTOP00000013307
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936475262,920 - 297,459 (+)Ensembl
RefSeq Acc Id: XM_021720884   ⟹   XP_021576559
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_004936475262,558 - 299,766 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040279033   ⟹   XP_040134967
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934959,289,309 - 59,326,531 (-)NCBI
Protein Sequences
Protein RefSeqs XP_040134967 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3257354 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_021576559   ⟸   XM_021720884
- Sequence:
RefSeq Acc Id: XP_040134967   ⟸   XM_040279033
RefSeq Acc Id: ENSSTOP00000013307   ⟸   ENSSTOT00000014856
Protein Domains
Aminotran_1_2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000014851 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000013307.3 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000014856.3 UniProtKB/TrEMBL
Gene3D-CATH 3.40.640.10 UniProtKB/TrEMBL
  3.90.1150.10 UniProtKB/TrEMBL
InterPro ALAT1/2-like UniProtKB/TrEMBL
  Aminotransferase_I/II UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_major UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_small UniProtKB/TrEMBL
NCBI Gene Gpt2 ENTREZGENE
PANTHER PTHR11751 UniProtKB/TrEMBL
Pfam Aminotran_1_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF53383 UniProtKB/TrEMBL
UniProt I3MNP3_ICTTR UniProtKB/TrEMBL