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Gene: Acp5 (acid phosphatase 5, tartrate resistant) Ictidomys tridecemlineatus

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Symbol:

Acp5

Name:

acid phosphatase 5, tartrate resistant

RGD ID:

12557961

Description:

ENCODES a protein that exhibits acid phosphatase activity (ortholog); hydrolase activity (ortholog); INVOLVED IN bone resorption (ortholog); cellular response to zinc ion starvation (ortholog); dephosphorylation (ortholog); ASSOCIATED WITH alpha-mannosidosis (ortholog); Alveolar Bone Loss (ortholog); Charcot-Marie-Tooth disease dominant intermediate B (ortholog); FOUND IN extracellular space (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

acid phosphatase 5, tartrate resistant, transcript variant X1; acid phosphatase 5, tartrate resistant, transcript variant X2; acid phosphatase 5, tartrate resistant, transcript variant X3; acid phosphatase 5, tartrate resistant, transcript variant X4; tartrate-resistant acid phosphatase type 5

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	208,712,098 - 208,756,454 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936659	1,598,177 - 1,600,262 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936659	1,598,252 - 1,642,615 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Acp5	Squirrel	Alveolar Bone Loss	treatment	ISO	RGD:2022	9068941	associated with hypertension, periodontal disease	RGD	PMID:33364953\|REF_RGD_ID:329956421
Acp5	Squirrel	Experimental Diabetes Mellitus		ISO	RGD:2022	9068941	protein:increased activity:femoral bone (rat)	RGD	PMID:19699734\|REF_RGD_ID:2315882
Acp5	Squirrel	Postmenopausal Osteoporosis		ISO	RGD:2022	9068941	protein:increased expression:femur (rat)	RGD	PMID:19736603\|REF_RGD_ID:2315910
Acp5	Squirrel	Stress Fractures		ISO	RGD:2022	9068941	protein:increased expression:tibia (rat)	RGD	PMID:19821772\|REF_RGD_ID:2315909

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Acp5	Squirrel	alpha-mannosidosis		ISO	RGD:10073	8554872	ClinVar Annotator: match by term: Deficiency of alpha-mannosidase	ClinVar	PMID:28492532
Acp5	Squirrel	Charcot-Marie-Tooth disease dominant intermediate B		ISO	RGD:10073	8554872	ClinVar Annotator: match by term: Charcot-Marie-Tooth disease dominant intermediate B	ClinVar	PMID:28492532
Acp5	Squirrel	Combined Immunodeficiency with Autoimmunity and Spondylometaphyseal Dysplasia		ISO	RGD:10073	8554872	ClinVar Annotator: match by term: Spondyloenchondrodysplasia with immune dysregulation	ClinVar	PMID:12786759\|PMID:13524805\|PMID:16470600\|PMID:17576681\|PMID:18924170\|PMID:21217752\|PMID:21217755\|PMID:2363422\|PMID:24033266\|PMID:25741868\|PMID:26346816\|PMID:26789720\|PMID:26951490\|PMID:27125509\|PMID:27390188\|PMID:27718324\|PMID:27943079\|PMID:28492532\|PMID:28740483\|PMID:31286717\|PMID:32214327\|PMID:37382551\|PMID:38347954\|PMID:9536098
Acp5	Squirrel	episodic ataxia type 2		ISO	RGD:10073	8554872	ClinVar Annotator: match by term: Episodic ataxia type 2	ClinVar	PMID:28492532
Acp5	Squirrel	genetic disease		ISO	RGD:10073	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:13524805\|PMID:21217752\|PMID:21217755\|PMID:2363422\|PMID:25741868\|PMID:26951490\|PMID:27125509\|PMID:27390188\|PMID:28492532\|PMID:28740483\|PMID:38347954
Acp5	Squirrel	glutaric acidemia I		ISO	RGD:10073	8554872	ClinVar Annotator: match by term: Glutaric aciduria, type 1	ClinVar	PMID:28492532

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Acp5	Squirrel	Experimental Liver Cirrhosis		ISO	RGD:10073	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:25380136
Acp5	Squirrel	obesity		ISO	RGD:10073	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:20882379
Acp5	Squirrel	secondary hyperparathyroidism		ISO	RGD:10073	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:21985997\|PMID:22373954
Acp5	Squirrel	Spondyloenchondrodysplasia		ISO	RGD:10073	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:21217752\|PMID:21217755

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Acp5	Squirrel	Combined Immunodeficiency with Autoimmunity and Spondylometaphyseal Dysplasia		ISO	RGD:10073	7240710		OMIM

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Acp5	Squirrel	bone morphogenesis	acts_upstream_of_or_within	IEA	UniProtKB:Q05117\|ensembl:ENSMUSP00000150903	150520179		Ensembl	GO_REF:0000107
Acp5	Squirrel	bone resorption		ISO	RGD:2022	9068941		RGD	PMID:20069278\|REF_RGD_ID:2315871
Acp5	Squirrel	bone resorption	acts_upstream_of_or_within	IEA	UniProtKB:Q05117\|ensembl:ENSMUSP00000150903	150520179		Ensembl	GO_REF:0000107
Acp5	Squirrel	bone resorption	involved_in	IEA	PANTHER:PTN001300238	150520179		TreeGrafter	GO_REF:0000118
Acp5	Squirrel	cellular response to zinc ion starvation		ISO	RGD:2022	9068941		RGD	PMID:21893222\|REF_RGD_ID:151667428
Acp5	Squirrel	defense response to Gram-positive bacterium	acts_upstream_of_or_within	IEA	UniProtKB:Q05117\|ensembl:ENSMUSP00000150903	150520179		Ensembl	GO_REF:0000107
Acp5	Squirrel	dephosphorylation	acts_upstream_of_or_within	ISO	RGD:10072	9068941	PMID:9308894	MGI	PMID:9308894
Acp5	Squirrel	multicellular organismal response to stress		ISO	RGD:2022	9068941	restraint	RGD	PMID:19113077\|REF_RGD_ID:2315906
Acp5	Squirrel	negative regulation of cell adhesion		ISO	RGD:2022	9068941		RGD	PMID:19854170\|REF_RGD_ID:2315877
Acp5	Squirrel	negative regulation of inflammatory response	acts_upstream_of_or_within	IEA	UniProtKB:Q05117\|ensembl:ENSMUSP00000150903	150520179		Ensembl	GO_REF:0000107
Acp5	Squirrel	negative regulation of interleukin-1 beta production	acts_upstream_of_or_within	IEA	UniProtKB:Q05117\|ensembl:ENSMUSP00000150903	150520179		Ensembl	GO_REF:0000107
Acp5	Squirrel	negative regulation of interleukin-12 production	acts_upstream_of_or_within	IEA	UniProtKB:Q05117\|ensembl:ENSMUSP00000150903	150520179		Ensembl	GO_REF:0000107
Acp5	Squirrel	negative regulation of macrophage cytokine production	acts_upstream_of_or_within	IEA	UniProtKB:Q05117\|ensembl:ENSMUSP00000150903	150520179		Ensembl	GO_REF:0000107
Acp5	Squirrel	negative regulation of nitric oxide biosynthetic process	acts_upstream_of_or_within	IEA	UniProtKB:Q05117\|ensembl:ENSMUSP00000150903	150520179		Ensembl	GO_REF:0000107
Acp5	Squirrel	negative regulation of superoxide anion generation	acts_upstream_of_or_within	IEA	UniProtKB:Q05117\|ensembl:ENSMUSP00000150903	150520179		Ensembl	GO_REF:0000107
Acp5	Squirrel	negative regulation of tumor necrosis factor production	acts_upstream_of_or_within	IEA	UniProtKB:Q05117\|ensembl:ENSMUSP00000150903	150520179		Ensembl	GO_REF:0000107
Acp5	Squirrel	nitric oxide biosynthetic process	acts_upstream_of	IEA	UniProtKB:Q05117\|ensembl:ENSMUSP00000150903	150520179		Ensembl	GO_REF:0000107
Acp5	Squirrel	ossification		ISO	RGD:2022	9068941		RGD	PMID:19403161\|REF_RGD_ID:2315903
Acp5	Squirrel	osteoclast differentiation		ISO	RGD:2022	9068941		RGD	PMID:19361364\|REF_RGD_ID:2315902
Acp5	Squirrel	positive regulation of cell migration		ISO	RGD:2022	9068941		RGD	PMID:19854170\|REF_RGD_ID:2315877
Acp5	Squirrel	response to cholesterol		ISO	RGD:2022	9068941		RGD	PMID:19110235\|REF_RGD_ID:2315908
Acp5	Squirrel	response to cytokine	acts_upstream_of_or_within	IEA	UniProtKB:Q05117\|ensembl:ENSMUSP00000150903	150520179		Ensembl	GO_REF:0000107
Acp5	Squirrel	response to ethanol		ISO	RGD:2022	9068941		RGD	PMID:22576626\|REF_RGD_ID:151667429
Acp5	Squirrel	response to insulin		ISO	RGD:2022	9068941		RGD	PMID:20818503\|REF_RGD_ID:151667419
Acp5	Squirrel	response to L-ascorbic acid		ISO	RGD:2022	9068941		RGD	PMID:19110235\|REF_RGD_ID:2315908
Acp5	Squirrel	response to lipopolysaccharide	acts_upstream_of_or_within	IEA	UniProtKB:Q05117\|ensembl:ENSMUSP00000150903	150520179		Ensembl	GO_REF:0000107
Acp5	Squirrel	response to macrophage colony-stimulating factor		ISO	RGD:2022	9068941		RGD	PMID:7669437\|REF_RGD_ID:151665777
Acp5	Squirrel	response to mechanical stimulus		ISO	RGD:2022	9068941		RGD	PMID:20833686\|REF_RGD_ID:151665823
Acp5	Squirrel	response to zinc ion		ISO	RGD:2022	9068941		RGD	PMID:19369052\|REF_RGD_ID:2315901
Acp5	Squirrel	superoxide anion generation	acts_upstream_of	IEA	UniProtKB:Q05117\|ensembl:ENSMUSP00000150903	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Acp5	Squirrel	extracellular space		ISO	RGD:2022	9068941		RGD	PMID:20003323\|REF_RGD_ID:2315874
Acp5	Squirrel	lysosome	located_in	IEA	UniProtKB:Q05117\|ensembl:ENSMUSP00000150903	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Acp5	Squirrel	acid phosphatase activity		ISO	RGD:2022	9068941		RGD	PMID:19854170\|REF_RGD_ID:2315877
Acp5	Squirrel	acid phosphatase activity	enables	IEA	UniRule:UR000436752	150520179		UniProt	GO_REF:0000104
Acp5	Squirrel	acid phosphatase activity	enables	IEA	InterPro:IPR024927	150520179		InterPro	GO_REF:0000002
Acp5	Squirrel	acid phosphatase activity	enables	IEA	UniProtKB:Q05117\|ensembl:ENSMUSP00000150903	150520179		Ensembl	GO_REF:0000107
Acp5	Squirrel	acid phosphatase activity	enables	IEA	EC:3.1.3.2	150520179		UniProt	GO_REF:0000003
Acp5	Squirrel	ferric iron binding	enables	IEA	UniProtKB:P13686\|ensembl:ENSP00000496973	150520179		Ensembl	GO_REF:0000107
Acp5	Squirrel	ferrous iron binding	enables	IEA	UniProtKB:P13686\|ensembl:ENSP00000496973	150520179		Ensembl	GO_REF:0000107
Acp5	Squirrel	hydrolase activity		ISO	RGD:2022	9068941		RGD	PMID:11890682\|REF_RGD_ID:619585
Acp5	Squirrel	hydrolase activity	enables	IEA	InterPro:IPR004843	150520179		InterPro	GO_REF:0000002
Acp5	Squirrel	hydrolase activity	enables	IEA	UniProtKB-KW:KW-0378	150520179		UniProt	GO_REF:0000043
Acp5	Squirrel	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	150520179		UniProt	GO_REF:0000043

PMID:22301074	PMID:30032202

Acp5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	208,712,098 - 208,756,454 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936659	1,598,177 - 1,600,262 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936659	1,598,252 - 1,642,615 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ACP5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	11,574,660 - 11,578,975 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	11,574,653 - 11,579,993 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	11,685,475 - 11,689,790 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	11,546,477 - 11,549,496 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	11,546,476 - 11,549,496	NCBI
Celera	19	11,580,213 - 11,584,539 (-)	NCBI		Celera
Cytogenetic Map	19	p13.2	NCBI
HuRef	19	11,259,840 - 11,264,071 (-)	NCBI		HuRef
CHM1_1	19	11,685,335 - 11,689,664 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	11,702,190 - 11,706,505 (-)	NCBI		T2T-CHM13v2.0

Acp5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	22,038,023 - 22,047,042 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	22,038,023 - 22,047,007 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	22,126,727 - 22,135,746 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	22,126,727 - 22,135,711 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	21,931,171 - 21,940,190 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	21,877,148 - 21,881,056 (-)	NCBI		MGSCv36	mm8
Celera	9	19,395,697 - 19,404,716 (-)	NCBI		Celera
Cytogenetic Map	9	A3	NCBI
cM Map	9	8.38	NCBI

Acp5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	28,939,984 - 28,946,639 (-)	NCBI		GRCr8
mRatBN7.2	8	20,663,984 - 20,670,604 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	20,663,985 - 20,667,929 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	24,693,289 - 24,698,588 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	22,990,432 - 22,995,731 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	20,893,525 - 20,899,471 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	23,142,733 - 23,149,067 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	23,142,734 - 23,148,396 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	23,197,095 - 23,202,903 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	8	22,052,728 - 22,058,674 (-)	NCBI		Celera
Cytogenetic Map	8	q13	NCBI

Acp5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	2,418,364 - 2,421,538 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955495	2,418,113 - 2,421,181 (+)	NCBI	ChiLan1.0	ChiLan1.0

ACP5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	16,486,997 - 16,495,640 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	15,482,421 - 15,489,613 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	11,120,451 - 11,125,167 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	11,832,575 - 11,836,881 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	11,832,575 - 11,835,203 (-)	Ensembl	panpan1.1		panPan2

ACP5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	49,812,444 - 49,816,262 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	49,814,032 - 49,816,260 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	49,684,989 - 49,687,385 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	50,330,836 - 50,334,545 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	50,332,449 - 50,334,544 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	49,542,471 - 49,544,878 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	49,968,636 - 49,971,025 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	50,211,593 - 50,213,981 (+)	NCBI		UU_Cfam_GSD_1.0

ACP5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	70,206,162 - 70,208,229 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	70,206,159 - 70,209,855 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	70,615,520 - 70,616,019 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Pig Cytomap	2	q12-q21	NCBI

ACP5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	10,488,572 - 10,493,508 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	10,488,460 - 10,491,519 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666074	9,350,068 - 9,354,653 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Acp5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	3,307,635 - 3,310,547 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624828	3,305,913 - 3,309,983 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_005336184	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013363321	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021733888	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021733889	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040290420	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040290421	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000003691 ⟹ ENSSTOP00000003304

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936659	1,598,177 - 1,600,262 (-)	Ensembl

RefSeq Acc Id:

XM_005336184 ⟹ XP_005336241

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	208,712,098 - 208,756,454 (+)	NCBI
SpeTri2.0	NW_004936659	1,598,252 - 1,642,615 (-)	NCBI

Sequence:

show sequence

GGTCAAGGCCAGTCCCTCCCAACCCTGAGGAAGGGGCGAGGAAGGAATCCTGAGCTTCAGCGCGTTAAGCAGGCGCTCCACCACTGAGCCACACCTCAGCCCTAACATACTGGCATTTTAAGAATTTG
TTCCTATCCCAGAAAGAAGACTGGCACCGCGTGGGCAAGTAGTTCCAGGCTGTTTTCACTTGGAGCGACCCACTTGTGCAAAGCAAGAGGGGAGCAAGGCCAGAACTGAAAGGAGAGCCAGCTTTTCT
CCACCGGGTCAGGGGCTTGGCATTAAGGCATGAAGGCCATTCATGGAACTGTGATGCTCTTTTAGGATCACCTAGAATCACAGACACTTAAAAGTGACGTCAGCGTATATAATACAGTCAGCCTCGAG
TTTGATCTTGACCGTTGCCAGCGTTGAGGCCTAAACCATCCCTTCCTCACCCTGCACATCTGGCTCTTTGATTCTGGCAGGAAGTGTGAACTTTGCTGGCCAAGTCTGAGATCAGAAACTCTTCTCAA
CCAACTGCCACCTATAAGAATCCGTCCAGGACCCCACACTTCATCCAGTCCTCATGCCTCCTTGGTCCCCTCCAGTCGACAACAACTCTGGACGTGTTTGTAGAGCACTGGTCAGTGATCCGCTTCCA
CCCCAGGGAATAAAGGCTCCGTGACCTCCACTTCTGCCCTGGAGCCCACCTGCCTCTCGTAGCCCCCACAGCCTGACTTGTGTCTCCCCCAGGATGGACACATGGATGGTGCTGCTGGTCCTGCAAGC
CTCGCTGCTGCTCCCTCTGGCTGACTGTACTGCCCCCACCCCCACCCTGCGCTTTGTGGCTGTGGGTGACTGGGGAGGAGTCCCCAATGCCCCGTTCCACACAGCCCGGGAGATGGCCAACGCTAAGG
AGATTGCCAGAACTGTGCAGACCATGGGTGCAGACTTGATCTTGTCCCTGGGGGACAACTTCTACTTCAATGGCGTGCATGATGTCAATGACAAGAGGTTCCAGGAGACCTTTGAGGATGTGTTCTCT
GACCGCTCCCTGCGTAATGTGCCCTGGTATGTGCTGGCGGGGAACCATGACCACCTGGGCAACGTCTCGGCACAGATTGCCTACTCCAAGGTCTCCAAGCGCTGGAACTTCCCCAGCCCCTTCTACCG
CCTGCACTTCAAGATCCCACGGACCAACACGTCTGTGGCCATCTTCATGCTGGACACTGTGACGCTGTGTGGCAACTCGAATGATTTCCTCAGCCAGCAGCCCGAGAGGCCCAAAGACCTGACGCTGG
CCCGAGCCCAGATGTCCTGGCTCAAGAAGCAGCTGGCGGCAGCCAAAGAGGACTACGTGCTGGTGGCCGGCCACTATCCTGTGTGGTCGATTGCTGAGCATGGACCCACCCGCTGCCTGGTCAAGCAC
CTGCAGCCACTGCTGGTCAAATATGGGGTCACTGCCTACCTGTGCGGCCATGACCACAACCTGCAGTACCTTCAAGATGAGAACGGAGTGGGCTACGTGCTGAGTGGGGCAGGCAACTTCATGGACCC
TTCGGTGCGGCACCAGCGCAAAGTCCCCAACGGCTACCTGCGCTTCCACTATGGGTCCGAGGACTCATTGGGTGGCTTTGCCTATGTGGAGATAAGCCCTAAGGAGATGACCATCACATACATCGAAG
CCTCGGGAAAATCCCTCTTCAAGACCAGCCTGCCCAAGCGAGCCAAACCCTGAACACCCAGGAGGACCCTGCCTGCCCACTTGGAGGCCGGAGGCAGTGGGGCTTCTGCAAGGGTGGTGCGTGGCCCT
GTGGAGACCCCAGCCACAGGTAGGTTGTCTCTCAGGCCCCTGGTGCACTGGCAGAGCAGGAAAGAGAGCCACAGCACCACATGGCCGTGGTGGCACAGATGCCCACACATGTGAAAGAAGCATGGACA
TGTGTTCCGGCCGGCATGTCACTCCCCACGGCCAGACTCACCTAGGCTGAGTTTTGGGGAGCCGGGAGGAAGAGAGGGAAAAACTTGTTCCTGAAGCAATCATGTTTCTGTTACTGCCATTTAATAAA
AGCATAACTGTCAAGGCTTCA

hide sequence

RefSeq Acc Id:

XM_013363321 ⟹ XP_013218775

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	208,712,098 - 208,756,454 (+)	NCBI
SpeTri2.0	NW_004936659	1,598,252 - 1,642,615 (-)	NCBI

Sequence:

show sequence

GGTCAAGGCCAGTCCCTCCCAACCCTGAGGAAGGGGCGAGGAAGGAATCCTGAGCTTCAGCGCG
TTAAGCAGGCGCTCCACCACTGAGCCACACCTCAGCCCTAACATACTGGCATTTTAAGAATTTGTTCCTATCCCAGAAAGAAGACTGGCACCGCGTGGGCAAGTAGTTCCAGGCTGTTTTCACTTGGA
GCGACCCACTTGTGCAAAGCAAGAGGGGAGCAAGGCCAGAACTGAAAGGAGAGCCAGCTTTTCTCCACCGGGTCAGGGGCTTGGCATTAAGGCATGAAGGCCATTCATGGAACTGTGATGCTCTTTTA
GGATCACCTAGAATCACAGACACTTAAAAGTGACGTCAGCGTATATAATACAGTCAGCCTCGAGTTTGATCTTGACCGTTGCCAGCGTTGAGGCCTAAACCATCCCTTCCTCACCCTGCACATCTGGC
TCTTTGATTCTGGCAGGAAGTGTGAACTTTGCTGGCCAAGTCTGAGATCAGAAACTCTTCTCAACCAACTGCCACCTATAAGAATCCGTCCAGGACCCCACACTTCATCCAGTCCTCATGCCTCCTTG
GTCCCCTCCAGTCGACAACAACTCTGGACGTGTTTGTAGAGCACTGGTCAGGGAATAAAGGCTCCGTGACCTCCACTTCTGCCCTGGAGCCCACCTGCCTCTCGTAGCCCCCACAGCCTGACTTGTGT
CTCCCCCAGGATGGACACATGGATGGTGCTGCTGGTCCTGCAAGCCTCGCTGCTGCTCCCTCTGGCTGACTGTACTGCCCCCACCCCCACCCTGCGCTTTGTGGCTGTGGGTGACTGGGGAGGAGTCC
CCAATGCCCCGTTCCACACAGCCCGGGAGATGGCCAACGCTAAGGAGATTGCCAGAACTGTGCAGACCATGGGTGCAGACTTGATCTTGTCCCTGGGGGACAACTTCTACTTCAATGGCGTGCATGAT
GTCAATGACAAGAGGTTCCAGGAGACCTTTGAGGATGTGTTCTCTGACCGCTCCCTGCGTAATGTGCCCTGGTATGTGCTGGCGGGGAACCATGACCACCTGGGCAACGTCTCGGCACAGATTGCCTA
CTCCAAGGTCTCCAAGCGCTGGAACTTCCCCAGCCCCTTCTACCGCCTGCACTTCAAGATCCCACGGACCAACACGTCTGTGGCCATCTTCATGCTGGACACTGTGACGCTGTGTGGCAACTCGAATG
ATTTCCTCAGCCAGCAGCCCGAGAGGCCCAAAGACCTGACGCTGGCCCGAGCCCAGATGTCCTGGCTCAAGAAGCAGCTGGCGGCAGCCAAAGAGGACTACGTGCTGGTGGCCGGCCACTATCCTGTG
TGGTCGATTGCTGAGCATGGACCCACCCGCTGCCTGGTCAAGCACCTGCAGCCACTGCTGGTCAAATATGGGGTCACTGCCTACCTGTGCGGCCATGACCACAACCTGCAGTACCTTCAAGATGAGAA
CGGAGTGGGCTACGTGCTGAGTGGGGCAGGCAACTTCATGGACCCTTCGGTGCGGCACCAGCGCAAAGTCCCCAACGGCTACCTGCGCTTCCACTATGGGTCCGAGGACTCATTGGGTGGCTTTGCCT
ATGTGGAGATAAGCCCTAAGGAGATGACCATCACATACATCGAAGCCTCGGGAAAATCCCTCTTCAAGACCAGCCTGCCCAAGCGAGCCAAACCCTGAACACCCAGGAGGACCCTGCCTGCCCACTTG
GAGGCCGGAGGCAGTGGGGCTTCTGCAAGGGTGGTGCGTGGCCCTGTGGAGACCCCAGCCACAGGTAGGTTGTCTCTCAGGCCCCTGGTGCACTGGCAGAGCAGGAAAGAGAGCCACAGCACCACATG
GCCGTGGTGGCACAGATGCCCACACATGTGAAAGAAGCATGGACATGTGTTCCGGCCGGCATGTCACTCCCCACGGCCAGACTCACCTAGGCTGAGTTTTGGGGAGCCGGGAGGAAGAGAGGGAAAAA
CTTGTTCCTGAAGCAATCATGTTTCTGTTACTGCCATTTAATAAAAGCATAACTGTCAAGGCTTCA

hide sequence

RefSeq Acc Id:

XM_021733888 ⟹ XP_021589563

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	208,753,249 - 208,756,454 (+)	NCBI
SpeTri2.0	NW_004936659	1,598,252 - 1,600,621 (-)	NCBI

Sequence:

show sequence

TCTCTAGTGATCCGCTTCCACCCCAGGGAATAAAGGCTCCGTGACCTCCACTTCTGCCCTGGAGCCCACCTGCCTCTCGTAGCCCCCACAGCCTGACTTGTGTCTCCCCCAGGATGGACACATGGATG
GTGCTGCTGGTCCTGCAAGCCTCGCTGCTGCTCCCTCTGGCTGACTGTACTGCCCCCACCCCCACCCTGCGCTTTGTGGCTGTGGGTGACTGGGGAGGAGTCCCCAATGCCCCGTTCCACACAGCCCG
GGAGATGGCCAACGCTAAGGAGATTGCCAGAACTGTGCAGACCATGGGTGCAGACTTGATCTTGTCCCTGGGGGACAACTTCTACTTCAATGGCGTGCATGATGTCAATGACAAGAGGTTCCAGGAGA
CCTTTGAGGATGTGTTCTCTGACCGCTCCCTGCGTAATGTGCCCTGGTATGTGCTGGCGGGGAACCATGACCACCTGGGCAACGTCTCGGCACAGATTGCCTACTCCAAGGTCTCCAAGCGCTGGAAC
TTCCCCAGCCCCTTCTACCGCCTGCACTTCAAGATCCCACGGACCAACACGTCTGTGGCCATCTTCATGCTGGACACTGTGACGCTGTGTGGCAACTCGAATGATTTCCTCAGCCAGCAGCCCGAGAG
GCCCAAAGACCTGACGCTGGCCCGAGCCCAGATGTCCTGGCTCAAGAAGCAGCTGGCGGCAGCCAAAGAGGACTACGTGCTGGTGGCCGGCCACTATCCTGTGTGGTCGATTGCTGAGCATGGACCCA
CCCGCTGCCTGGTCAAGCACCTGCAGCCACTGCTGGTCAAATATGGGGTCACTGCCTACCTGTGCGGCCATGACCACAACCTGCAGTACCTTCAAGATGAGAACGGAGTGGGCTACGTGCTGAGTGGG
GCAGGCAACTTCATGGACCCTTCGGTGCGGCACCAGCGCAAAGTCCCCAACGGCTACCTGCGCTTCCACTATGGGTCCGAGGACTCATTGGGTGGCTTTGCCTATGTGGAGATAAGCCCTAAGGAGAT
GACCATCACATACATCGAAGCCTCGGGAAAATCCCTCTTCAAGACCAGCCTGCCCAAGCGAGCCAAACCCTGAACACCCAGGAGGACCCTGCCTGCCCACTTGGAGGCCGGAGGCAGTGGGGCTTCTG
CAAGGGTGGTGCGTGGCCCTGTGGAGACCCCAGCCACAGGTAGGTTGTCTCTCAGGCCCCTGGTGCACTGGCAGAGCAGGAAAGAGAGCCACAGCACCACATGGCCGTGGTGGCACAGATGCCCACAC
ATGTGAAAGAAGCATGGACATGTGTTCCGGCCGGCATGTCACTCCCCACGGCCAGACTCACCTAGGCTGAGTTTTGGGGAGCCGGGAGGAAGAGAGGGAAAAACTTGTTCCTGAAGCAATCATGTTTC
TGTTACTGCCATTTAATAAAAGCATAACTGTCAAGGCTTCA

hide sequence

RefSeq Acc Id:

XM_021733889 ⟹ XP_021589564

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	208,752,017 - 208,756,454 (+)	NCBI
SpeTri2.0	NW_004936659	1,598,252 - 1,601,881 (-)	NCBI

Sequence:

show sequence

GGGCCCGCGGGCAGGGCCGGCCGGCTGCCACCTTCTTAAAACCCGGGCAGCCCCAGAGCGAGCA
CCCTGTGGATCTGCAGCTCAGCTCGGGTGGCAGCGCTCGGGCTCGACCCTGAACCCACGACCGCAGATGGACACATGGATGGTGCTGCTGGTCCTGCAAGCCTCGCTGCTGCTCCCTCTGGCTGACTG
TACTGCCCCCACCCCCACCCTGCGCTTTGTGGCTGTGGGTGACTGGGGAGGAGTCCCCAATGCCCCGTTCCACACAGCCCGGGAGATGGCCAACGCTAAGGAGATTGCCAGAACTGTGCAGACCATGG
GTGCAGACTTGATCTTGTCCCTGGGGGACAACTTCTACTTCAATGGCGTGCATGATGTCAATGACAAGAGGTTCCAGGAGACCTTTGAGGATGTGTTCTCTGACCGCTCCCTGCGTAATGTGCCCTGG
TATGTGCTGGCGGGGAACCATGACCACCTGGGCAACGTCTCGGCACAGATTGCCTACTCCAAGGTCTCCAAGCGCTGGAACTTCCCCAGCCCCTTCTACCGCCTGCACTTCAAGATCCCACGGACCAA
CACGTCTGTGGCCATCTTCATGCTGGACACTGTGACGCTGTGTGGCAACTCGAATGATTTCCTCAGCCAGCAGCCCGAGAGGCCCAAAGACCTGACGCTGGCCCGAGCCCAGATGTCCTGGCTCAAGA
AGCAGCTGGCGGCAGCCAAAGAGGACTACGTGCTGGTGGCCGGCCACTATCCTGTGTGGTCGATTGCTGAGCATGGACCCACCCGCTGCCTGGTCAAGCACCTGCAGCCACTGCTGGTCAAATATGGG
GTCACTGCCTACCTGTGCGGCCATGACCACAACCTGCAGTACCTTCAAGATGAGAACGGAGTGGGCTACGTGCTGAGTGGGGCAGGCAACTTCATGGACCCTTCGGTGCGGCACCAGCGCAAAGTCCC
CAACGGCTACCTGCGCTTCCACTATGGGTCCGAGGACTCATTGGGTGGCTTTGCCTATGTGGAGATAAGCCCTAAGGAGATGACCATCACATACATCGAAGCCTCGGGAAAATCCCTCTTCAAGACCA
GCCTGCCCAAGCGAGCCAAACCCTGAACACCCAGGAGGACCCTGCCTGCCCACTTGGAGGCCGGAGGCAGTGGGGCTTCTGCAAGGGTGGTGCGTGGCCCTGTGGAGACCCCAGCCACAGGTAGGTTG
TCTCTCAGGCCCCTGGTGCACTGGCAGAGCAGGAAAGAGAGCCACAGCACCACATGGCCGTGGTGGCACAGATGCCCACACATGTGAAAGAAGCATGGACATGTGTTCCGGCCGGCATGTCACTCCCC
ACGGCCAGACTCACCTAGGCTGAGTTTTGGGGAGCCGGGAGGAAGAGAGGGAAAAACTTGTTCCTGAAGCAATCATGTTTCTGTTACTGCCATTTAATAAAAGCATAACTGTCAAGGCTTCA

hide sequence

RefSeq Acc Id:

XM_040290420 ⟹ XP_040146354

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	208,752,018 - 208,756,454 (+)	NCBI

RefSeq Acc Id:

XM_040290421 ⟹ XP_040146355

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	208,712,098 - 208,756,454 (+)	NCBI


Protein RefSeqs	XP_005336241	(Get FASTA)	NCBI Sequence Viewer
	XP_013218775	(Get FASTA)	NCBI Sequence Viewer
	XP_021589563	(Get FASTA)	NCBI Sequence Viewer
	XP_021589564	(Get FASTA)	NCBI Sequence Viewer
	XP_040146354	(Get FASTA)	NCBI Sequence Viewer
	XP_040146355	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000003304.2
GenBank Protein	KAG3280239	(Get FASTA)	NCBI Sequence Viewer
	KAG3280240	(Get FASTA)	NCBI Sequence Viewer
	KAG3280241	(Get FASTA)	NCBI Sequence Viewer
	KAG3280242	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_013218775 ⟸ XM_013363321

- UniProtKB:

I3M2S1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDTWMVLLVLQASLLLPLADCTAPTPTLRFVAVGDWGGVPNAPFHTAREMANAKEIARTVQTMGADLILSLGDNFYFNGVHDVNDKRFQETFEDVFSDRSLRNVPWYVLAGNHDHLGNVSAQIAYSKV
SKRWNFPSPFYRLHFKIPRTNTSVAIFMLDTVTLCGNSNDFLSQQPERPKDLTLARAQMSWLKKQLAAAKEDYVLVAGHYPVWSIAEHGPTRCLVKHLQPLLVKYGVTAYLCGHDHNLQYLQDENGVG
YVLSGAGNFMDPSVRHQRKVPNGYLRFHYGSEDSLGGFAYVEISPKEMTITYIEASGKSLFKTSLPKRAKP

hide sequence

RefSeq Acc Id:

XP_005336241 ⟸ XM_005336184

- UniProtKB:

I3M2S1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDTWMVLLVLQASLLLPLADCTAPTPTLRFVAVGDWGGVPNAPFHTAREMANAKEIARTVQTMGADLILSLGDNFYFNGVHDVNDKRFQETFEDVFSDRSLRNVPWYVLAGNHDHLGNVSAQIAYSKV
SKRWNFPSPFYRLHFKIPRTNTSVAIFMLDTVTLCGNSNDFLSQQPERPKDLTLARAQMSWLKKQLAAAKEDYVLVAGHYPVWSIAEHGPTRCLVKHLQPLLVKYGVTAYLCGHDHNLQYLQDENGVG
YVLSGAGNFMDPSVRHQRKVPNGYLRFHYGSEDSLGGFAYVEISPKEMTITYIEASGKSLFKTSLPKRAKP

hide sequence

RefSeq Acc Id:

XP_021589564 ⟸ XM_021733889

- UniProtKB:

I3M2S1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDTWMVLLVLQASLLLPLADCTAPTPTLRFVAVGDWGGVPNAPFHTAREMANAKEIARTVQTMGADLILSLGDNFYFNGVHDVNDKRFQETFEDVFSDRSLRNVPWYVLAGNHDHLGNVSAQIAYSKV
SKRWNFPSPFYRLHFKIPRTNTSVAIFMLDTVTLCGNSNDFLSQQPERPKDLTLARAQMSWLKKQLAAAKEDYVLVAGHYPVWSIAEHGPTRCLVKHLQPLLVKYGVTAYLCGHDHNLQYLQDENGVG
YVLSGAGNFMDPSVRHQRKVPNGYLRFHYGSEDSLGGFAYVEISPKEMTITYIEASGKSLFKTSLPKRAKP

hide sequence

RefSeq Acc Id:

XP_021589563 ⟸ XM_021733888

- UniProtKB:

I3M2S1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDTWMVLLVLQASLLLPLADCTAPTPTLRFVAVGDWGGVPNAPFHTAREMANAKEIARTVQTMGADLILSLGDNFYFNGVHDVNDKRFQETFEDVFSDRSLRNVPWYVLAGNHDHLGNVSAQIAYSKV
SKRWNFPSPFYRLHFKIPRTNTSVAIFMLDTVTLCGNSNDFLSQQPERPKDLTLARAQMSWLKKQLAAAKEDYVLVAGHYPVWSIAEHGPTRCLVKHLQPLLVKYGVTAYLCGHDHNLQYLQDENGVG
YVLSGAGNFMDPSVRHQRKVPNGYLRFHYGSEDSLGGFAYVEISPKEMTITYIEASGKSLFKTSLPKRAKP

hide sequence

RefSeq Acc Id:	XP_040146355 ⟸ XM_040290421
- UniProtKB:	I3M2S1 (UniProtKB/TrEMBL)

Protein Domains

Calcineurin-like phosphoesterase

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000003699	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000003691.3	UniProtKB/TrEMBL
Gene3D-CATH	3.60.21.10	UniProtKB/TrEMBL
InterPro	Acid_PPase	UniProtKB/TrEMBL
	Calcineurin-like_PHP_ApaH	UniProtKB/TrEMBL
	Metallo-depent_PP-like	UniProtKB/TrEMBL
	Metallophosphoesterase_PAP	UniProtKB/TrEMBL
NCBI Gene	Acp5	ENTREZGENE
PANTHER	TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5	UniProtKB/TrEMBL
	TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5	UniProtKB/TrEMBL
Pfam	Metallophos	UniProtKB/TrEMBL
PIRSF	Acid_Ptase_5	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56300	UniProtKB/TrEMBL
UniProt	I3M2S1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM