Chka (choline kinase alpha) - Rat Genome Database

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Gene: Chka (choline kinase alpha) Ictidomys tridecemlineatus
Analyze
Symbol: Chka
Name: choline kinase alpha
RGD ID: 12651262
Description: ENCODES a protein that exhibits ATP binding (ortholog); choline binding (ortholog); choline kinase activity (ortholog); INVOLVED IN cellular response to glucose starvation (ortholog); choline metabolic process (ortholog); ethanolamine metabolic process (ortholog); PARTICIPATES IN glycerophospholipid metabolic pathway; ASSOCIATED WITH Aicardi-Goutieres Syndrome 3 (ortholog); colon adenoma (ortholog); colon cancer (ortholog); FOUND IN cytosol (ortholog); lipid droplet (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049475,589,711 - 5,626,074 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365992,001,673 - 2,067,399 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365992,031,953 - 2,068,423 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Chka
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049475,589,711 - 5,626,074 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365992,001,673 - 2,067,399 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365992,031,953 - 2,068,423 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHKA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381168,052,859 - 68,121,388 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1168,052,859 - 68,121,444 (-)EnsemblGRCh38hg38GRCh38
GRCh371167,820,326 - 67,888,855 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361167,576,902 - 67,645,434 (-)NCBINCBI36Build 36hg18NCBI36
Celera1165,154,000 - 65,222,386 (-)NCBICelera
Cytogenetic Map11q13.2NCBI
HuRef1164,155,675 - 64,231,363 (-)NCBIHuRef
CHM1_11167,704,080 - 67,773,223 (-)NCBICHM1_1
T2T-CHM13v2.01168,056,500 - 68,125,033 (-)NCBIT2T-CHM13v2.0
Chka
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39193,901,585 - 3,944,368 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl193,901,773 - 3,944,369 (+)EnsemblGRCm39 Ensembl
GRCm38193,851,585 - 3,894,369 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl193,851,773 - 3,894,369 (+)EnsemblGRCm38mm10GRCm38
MGSCv37193,851,773 - 3,894,367 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36193,851,773 - 3,894,369 (+)NCBIMGSCv36mm8
Celera193,732,122 - 3,774,742 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map193.57NCBI
Chka
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81210,506,069 - 210,554,753 (+)NCBIGRCr8
mRatBN7.21201,076,804 - 201,125,517 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1201,076,860 - 201,125,516 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1209,450,243 - 209,498,722 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01216,538,854 - 216,587,504 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01209,213,056 - 209,261,706 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01219,076,618 - 219,126,221 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,077,771 - 219,126,220 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01225,950,340 - 225,998,826 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41206,368,963 - 206,418,526 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11206,522,415 - 206,571,978 (+)NCBI
Celera1198,630,045 - 198,678,068 (+)NCBICelera
Cytogenetic Map1q43NCBI
Chka
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542217,710,434 - 17,766,256 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542217,710,981 - 17,766,256 (+)NCBIChiLan1.0ChiLan1.0
CHKA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2969,003,455 - 69,071,569 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11170,046,717 - 70,114,782 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01163,134,776 - 63,202,516 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11166,443,275 - 66,486,517 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1166,444,406 - 66,510,221 (-)Ensemblpanpan1.1panPan2
CHKA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11849,717,512 - 49,784,653 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1849,745,437 - 49,781,882 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1848,326,328 - 48,395,961 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01850,633,890 - 50,707,854 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1850,633,254 - 50,704,171 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11849,851,764 - 49,917,733 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01849,426,624 - 49,492,553 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01850,219,763 - 50,289,786 (+)NCBIUU_Cfam_GSD_1.0
CHKA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl24,788,213 - 4,846,665 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.124,788,508 - 4,846,667 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.223,416,315 - 3,474,471 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CHKA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.116,411,606 - 6,482,508 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666038103,689,653 - 103,760,737 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chka
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476718,744,547 - 18,807,352 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476718,744,647 - 18,807,352 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000011507   ⟹   ENSSTOP00000010328
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365992,001,673 - 2,067,399 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000025335   ⟹   ENSSTOP00000019469
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365992,031,445 - 2,067,399 (+)Ensembl
RefSeq Acc Id: XM_013362038   ⟹   XP_013217492
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244049475,589,711 - 5,626,074 (+)NCBI
SpeTri2.0NW_0049365992,031,953 - 2,068,423 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040284009   ⟹   XP_040139943
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244049475,589,711 - 5,626,074 (+)NCBI
RefSeq Acc Id: XM_040284010   ⟹   XP_040139944
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244049475,589,711 - 5,626,074 (+)NCBI
RefSeq Acc Id: XM_040284011   ⟹   XP_040139945
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244049475,599,838 - 5,626,074 (+)NCBI
RefSeq Acc Id: XM_040284012   ⟹   XP_040139946
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244049475,589,711 - 5,626,074 (+)NCBI
RefSeq Acc Id: XM_040284014   ⟹   XP_040139948
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244049475,589,711 - 5,626,074 (+)NCBI
RefSeq Acc Id: XP_013217492   ⟸   XM_013362038
- Peptide Label: isoform X1
- UniProtKB: I3N523 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040139948   ⟸   XM_040284014
- Peptide Label: isoform X4
RefSeq Acc Id: XP_040139946   ⟸   XM_040284012
- Peptide Label: isoform X4
RefSeq Acc Id: XP_040139943   ⟸   XM_040284009
- Peptide Label: isoform X2
- UniProtKB: I3N523 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040139944   ⟸   XM_040284010
- Peptide Label: isoform X3
- UniProtKB: I3N523 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040139945   ⟸   XM_040284011
- Peptide Label: isoform X4
Ensembl Acc Id: ENSSTOP00000010328   ⟸   ENSSTOT00000011507
Ensembl Acc Id: ENSSTOP00000019469   ⟸   ENSSTOT00000025335


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000011503 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000011507.3 UniProtKB/TrEMBL
  ENSSTOT00000025335.2 UniProtKB/TrEMBL
Gene3D-CATH 3.90.1200.10 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
NCBI Gene Chka ENTREZGENE
PANTHER CHOLINE KINASE ALPHA UniProtKB/TrEMBL
  CHOLINE/ETHANOALAMINE KINASE UniProtKB/TrEMBL
Pfam Choline_kinase UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt I3MHG9_ICTTR UniProtKB/TrEMBL
  I3N523 ENTREZGENE, UniProtKB/TrEMBL