Kalrn (kalirin, RhoGEF kinase) - Rat Genome Database

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Gene: Kalrn (kalirin, RhoGEF kinase) Rattus norvegicus
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Symbol: Kalrn
Name: kalirin, RhoGEF kinase
RGD ID: 621865
Description: Enables enzyme binding activity. Involved in several processes, including regulation of dendrite development; regulation of modification of postsynaptic actin cytoskeleton; and regulation of neurotransmitter receptor localization to postsynaptic specialization membrane. Located in neuronal cell body and perinuclear region of cytoplasm. Is active in glutamatergic synapse; postsynaptic density; and presynapse. Human ortholog(s) of this gene implicated in cerebral atherosclerosis; cerebral infarction; and coronary artery disease. Orthologous to human KALRN (kalirin RhoGEF kinase); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cyclin B1; Duo; Hapip; huntingtin-associated protein interacting protein (duo); huntingtin-associated protein-interacting protein; kalirin; P-CIP10; PAM COOH-terminal interactor protein 10; serine/threonine kinase with Dbl- and pleckstrin homology domain; serine/threonine-protein kinase with Dbl- and pleckstrin homology domain
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81179,703,345 - 80,309,210 (+)NCBIGRCr8
mRatBN7.21166,198,155 - 66,803,166 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1166,198,173 - 66,797,610 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1175,087,947 - 75,631,070 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01167,750,338 - 68,292,956 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01166,780,418 - 67,323,530 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01169,484,293 - 70,025,682 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1169,484,293 - 70,025,633 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01172,575,016 - 73,115,328 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41168,124,348 - 68,611,336 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11168,205,034 - 68,668,925 (+)NCBI
Celera1165,708,953 - 66,248,259 (+)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
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Original Reference(s)
KalrnRatcerebral atherosclerosis susceptibilityISOKALRN (Homo sapiens)329956416DNA:SNP:intron: (rs6438833) (human)RGD 
KalrnRatcerebral infarction susceptibilityISOKALRN (Homo sapiens)11085239DNA:SNP:intron: (rs6438833) (human)RGD 
KalrnRatcerebral infarction sexual_dimorphismISOKALRN (Homo sapiens)329956420DNA:SNPs more ...RGD 
KalrnRatcoronary artery disease onsetISOKALRN (Homo sapiens)329970276associated with nicotine dependence and DNA:SNPs:multipleRGD 
KalrnRatcoronary artery disease susceptibilityISOKALRN (Homo sapiens)329956419associated with type 2 diabetes mellitus and DNA:SNP:intron: (rs9289231) T>G (human)RGD 
KalrnRatcoronary artery disease susceptibilityISOKALRN (Homo sapiens)329955537DNA:SNP:intron: (rs9289231) T>G (human)RGD 
KalrnRatcoronary artery disease severityISOKALRN (Homo sapiens)11076452DNA:SNP:intron: (rs9289231) (human) RGD 
Object Symbol
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Original Reference(s)
KalrnRatalkaptonuria  ISOKALRN (Homo sapiens)8554872ClinVar Annotator: match by term: AlkaptonuriaClinVarPMID:12501223 more ...
KalrnRatCoronary Disease  ISOKALRN (Homo sapiens)8554872ClinVar Annotator: match by term: Coronary heart disease more ...ClinVarPMID:17357071 and PMID:25741868
KalrnRatfamilial hypocalciuric hypercalcemia  ISOKALRN (Homo sapiens)8554872ClinVar Annotator: match by term: Familial hypocalciuric hypercalcemiaClinVarPMID:28492532
KalrnRatFamilial Thoracic Aortic Aneurysm 7  ISOKALRN (Homo sapiens)8554872ClinVar Annotator: match by term: Aortic aneurysm and familial thoracic 7ClinVarPMID:28492532
KalrnRatPrimary Lymphedema with Myelodysplasia  ISOKALRN (Homo sapiens)8554872ClinVar more ...ClinVarPMID:19449416 more ...

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Original Reference(s)
KalrnRat1,2-dimethylhydrazine multiple interactionsISOKalrn (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of KALRN mRNACTDPMID:22206623
KalrnRat17beta-estradiol decreases expressionISOKALRN (Homo sapiens)6480464Estradiol results in decreased expression of KALRN mRNACTDPMID:31614463
KalrnRat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOKalrn (Mus musculus)6480464[2 more ...CTDPMID:25510870
KalrnRat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISOKalrn (Mus musculus)6480464[2 more ...CTDPMID:25510870
KalrnRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOKalrn (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of KALRN mRNACTDPMID:18796159
KalrnRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of KALRN mRNACTDPMID:32109520
KalrnRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOKalrn (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of KALRN mRNACTDPMID:26377647
KalrnRat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of KALRN mRNACTDPMID:22298810
KalrnRat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642 more ...CTDPMID:32109520
KalrnRat2,4-dinitrobenzenesulfonic acid increases expressionISOKalrn (Mus musculus)64804642 and 4-dinitrobenzenesulfonic acid results in increased expression of KALRN mRNACTDPMID:30116771
KalrnRat2,4-dinitrobenzenesulfonic acid multiple interactionsISOKalrn (Mus musculus)6480464[2 and 4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of KALRN mRNACTDPMID:30116771
KalrnRat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of KALRN mRNACTDPMID:21346803
KalrnRat3,4-methylenedioxymethamphetamine decreases expressionEXP 6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of KALRN mRNACTDPMID:30071829
KalrnRat3H-1,2-dithiole-3-thione affects expressionEXP 64804641 and 2-dithiol-3-thione affects the expression of KALRN mRNACTDPMID:19162173
KalrnRat4,4'-sulfonyldiphenol decreases expressionISOKalrn (Mus musculus)6480464bisphenol S results in decreased expression of KALRN mRNACTDPMID:39298647
KalrnRat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of KALRN mRNACTDPMID:24780913
KalrnRataflatoxin B1 decreases expressionISOKALRN (Homo sapiens)6480464Aflatoxin B1 results in decreased expression of KALRN mRNACTDPMID:22100608
KalrnRataflatoxin B1 increases methylationISOKALRN (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of KALRN intronCTDPMID:30157460
KalrnRatAflatoxin B2 alpha increases methylationISOKALRN (Homo sapiens)6480464aflatoxin B2 results in increased methylation of KALRN intronCTDPMID:30157460
KalrnRatammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of KALRN mRNACTDPMID:16483693

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Biological Process
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Original Reference(s)
KalrnRatadult locomotory behavior acts_upstream_of_or_withinISOKalrn (Mus musculus)1624291MGI:5551305 PMID:23116210RGDPMID:23116210
KalrnRataxon guidance involved_inIBAFB:FBgn0024277 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
KalrnRataxonogenesis  IDA 628431 RGD 
KalrnRathabituation acts_upstream_of_or_withinISOKalrn (Mus musculus)1624291MGI:5551305 PMID:23116210RGDPMID:23116210
KalrnRatintracellular signal transduction involved_inIDA 628431PMID:12177196HGNC-UCL 
KalrnRatintracellular signal transduction  IDA 628431 RGD 
KalrnRatintracellular signal transduction involved_inIBAPANTHER:PTN002737294 and Kalrn (Rattus norvegicus)1600115GO_REF:0000033GO_CentralGO_REF:0000033
KalrnRatlactation acts_upstream_of_or_withinISOKalrn (Mus musculus)1624291MGI:5551305 PMID:23116210RGDPMID:23116210
KalrnRatmaternal behavior acts_upstream_of_or_withinISOKalrn (Mus musculus)1624291MGI:5551305 PMID:23116210RGDPMID:23116210
KalrnRatmaternal process involved in parturition acts_upstream_of_or_withinISOKalrn (Mus musculus)1624291MGI:5551305 PMID:23116210RGDPMID:23116210
KalrnRatmemory acts_upstream_of_or_withinISOKalrn (Mus musculus)1624291MGI:4358076 PMID:19625617RGDPMID:19625617
KalrnRatnegative regulation of growth hormone secretion acts_upstream_of_or_withinISOKalrn (Mus musculus)1624291MGI:5551305 PMID:23116210RGDPMID:23116210
KalrnRatnervous system development involved_inIDA 628431PMID:12177196HGNC-UCL 
KalrnRatnervous system development  IDA 628431 RGD 
KalrnRatneuromuscular junction development acts_upstream_of_or_withinISOKalrn (Mus musculus)1624291MGI:5551305 PMID:23116210RGDPMID:23116210
KalrnRatpositive regulation of dendritic spine morphogenesis acts_upstream_of_or_withinISOKalrn (Mus musculus)1624291MGI:4358076 PMID:19625617RGDPMID:19625617
KalrnRatpositive regulation of GTPase activity acts_upstream_of_or_withinISOKalrn (Mus musculus)1624291MGI:4358076 PMID:19625617RGDPMID:19625617
KalrnRatregulation of dendrite development  IDA 1358370 RGD 
KalrnRatregulation of modification of postsynaptic actin cytoskeleton involved_inIMP 12050112PMID:18031682SynGO 
KalrnRatregulation of modification of postsynaptic actin cytoskeleton involved_inIDA 12050112PMID:18031682SynGO 
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Cellular Component
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Original Reference(s)
KalrnRatcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
KalrnRatcytoplasm is_active_inIBAMGI:1277173 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
KalrnRatcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
KalrnRatcytoskeleton located_inIEAUniProtKB-SubCell:SL-00901600115GO_REF:0000044UniProtGO_REF:0000044
KalrnRatcytoskeleton located_inIEAUniProtKB-KW:KW-02061600115GO_REF:0000043UniProtGO_REF:0000043
KalrnRatcytosol located_inISOKALRN (Homo sapiens) more ...1624291 RGDGO_REF:0000052
KalrnRatextrinsic component of membrane is_active_inIBAFB:FBgn0024277 and PANTHER:PTN0014817811600115GO_REF:0000033GO_CentralGO_REF:0000033
KalrnRatglutamatergic synapse is_active_inIDA 12050112PMID:18031682SynGO 
KalrnRatglutamatergic synapse is_active_inIMP 12050112PMID:18031682SynGO 
KalrnRatneuronal cell body  IDA 727293 RGD 
KalrnRatnucleoplasm located_inISOKALRN (Homo sapiens) more ...1624291 RGDGO_REF:0000052
KalrnRatperinuclear region of cytoplasm  IDA 727293 RGD 
KalrnRatpostsynaptic density is_active_inIDA 12050112PMID:18031682SynGO 
KalrnRatpostsynaptic density is_active_inIBAPANTHER:PTN002737294 and Kalrn (Rattus norvegicus)1600115GO_REF:0000033GO_CentralGO_REF:0000033
KalrnRatpostsynaptic density is_active_inIMP 12050112PMID:18031682SynGO 
KalrnRatpresynapse is_active_inEXP 13702180PMID:23622064SynGO 
KalrnRatpresynapse is_active_inIDA 13702180PMID:23622064SynGO 
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Molecular Function
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Original Reference(s)
KalrnRatATP binding enablesIEAUniRule:UR0015033411600115GO_REF:0000104UniProtGO_REF:0000104
KalrnRatATP binding enablesIEAInterPro:IPR000719 and InterPro:IPR0174411600115GO_REF:0000002InterProGO_REF:0000002
KalrnRatATP binding enablesIEAUniProtKB-KW:KW-00671600115GO_REF:0000043UniProtGO_REF:0000043
KalrnRatenzyme binding  IPIPam (Rattus norvegicus)728662 RGD 
KalrnRatguanyl-nucleotide exchange factor activity enablesTAS 628431PMID:12177196HGNC-UCL 
KalrnRatguanyl-nucleotide exchange factor activity  TAS 628431 RGD 
KalrnRatguanyl-nucleotide exchange factor activity enablesIBAFB:FBgn0024277 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
KalrnRatguanyl-nucleotide exchange factor activity enablesIEAInterPro:IPR0002191600115GO_REF:0000002InterProGO_REF:0000002
KalrnRatguanyl-nucleotide exchange factor activity enablesIEAUniProtKB-KW:KW-03441600115GO_REF:0000043UniProtGO_REF:0000043
KalrnRatguanyl-nucleotide exchange factor activity enablesISOKALRN (Homo sapiens)1624291 PMID:12546821RGDPMID:12546821
KalrnRatkinase activity enablesIEAUniProtKB-KW:KW-04181600115GO_REF:0000043UniProtGO_REF:0000043
KalrnRatmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
KalrnRatnucleotide binding enablesIEAUniProtKB-KW:KW-05471600115GO_REF:0000043UniProtGO_REF:0000043
KalrnRatnucleotide binding enablesIEAUniRule:UR0015033411600115GO_REF:0000104UniProtGO_REF:0000104
KalrnRatprotein binding  IPIHap1 (Rattus norvegicus)728800 RGD 
KalrnRatprotein binding enablesIPIUniProtKB:Q62765150521626PMID:31801062IntAct 
KalrnRatprotein binding enablesIPIUniProtKB:Q99K10150521626PMID:31801062IntAct 
KalrnRatprotein binding enablesISOKALRN (Homo sapiens)1624291UniProtKB:P0DTD1-PRO_0000449631 more ...RGDPMID:36217029
KalrnRatprotein binding enablesISOKALRN (Homo sapiens) and UniProtKB:O60229-21624291UniProtKB:Q9Y6H5-1 and PMID:23284848RGDPMID:23284848
KalrnRatprotein binding enablesIPIUniProtKB:P54256728800PMID:9285789IntAct 
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Imported Annotations - PID (archival)

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Original Reference(s)
KalrnRatephrin - ephrin receptor bidirectional signaling axis  ISOKALRN (Homo sapiens)6484113 PIDPID:200052

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#
Reference Title
Reference Citation
1. Novel proteins that interact with the COOH-terminal cytosolic routing determinants of an integral membrane peptide-processing enzyme. Alam MR, etal., J Biol Chem 1996 Nov 8;271(45):28636-40.
2. Kalirin, a cytosolic protein with spectrin-like and GDP/GTP exchange factor-like domains that interacts with peptidylglycine alpha-amidating monooxygenase, an integral membrane peptide-processing enzyme. Alam MR, etal., J Biol Chem 1997 May 9;272(19):12667-75.
3. The Kalirin Gene rs9289231 Polymorphism as a Novel Predisposing Marker for Coronary Artery Disease. Boroumand M, etal., Lab Med. 2014 Fall;45(4):302-8. doi: 10.1309/LMLS813ZDPHRFLUU.
4. Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses. Boyken J, etal., Neuron. 2013 Apr 24;78(2):285-97. doi: 10.1016/j.neuron.2013.02.027.
5. Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain. Colomer V, etal., Hum Mol Genet 1997 Sep;6(9):1519-25.
6. Genetic Variation of the Kalirin Gene is Associated with ICAS in the Chinese Population. Dang M, etal., J Mol Neurosci. 2018 Oct;66(2):157-162. doi: 10.1007/s12031-018-1130-2. Epub 2018 Sep 19.
7. KALRN Rare and Common Variants and Susceptibility to Ischemic Stroke in Chinese Han Population. Dang M, etal., Neuromolecular Med. 2015 Sep;17(3):241-50. doi: 10.1007/s12017-015-8352-z. Epub 2015 Apr 28.
8. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
9. Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1. Hayashi-Takagi A, etal., Nat Neurosci. 2010 Mar;13(3):327-32. Epub 2010 Feb 7.
10. Validation study of genetic associations with coronary artery disease on chromosome 3q13-21 and potential effect modification by smoking. Horne BD, etal., Ann Hum Genet. 2009 Nov;73(Pt 6):551-8. doi: 10.1111/j.1469-1809.2009.00540.x. Epub 2009 Aug 25.
11. Isoforms of kalirin, a neuronal Dbl family member, generated through use of different 5'- and 3'-ends along with an internal translational initiation site. Johnson RC, etal., J Biol Chem 2000 Jun 23;275(25):19324-33.
12. Genetic Variant of Kalirin Gene Is Associated with Ischemic Stroke in a Chinese Han Population. Li H, etal., Biomed Res Int. 2017;2017:6594271. doi: 10.1155/2017/6594271. Epub 2017 Jun 19.
13. Kalirin, a multifunctional Rho guanine nucleotide exchange factor, is necessary for maintenance of hippocampal pyramidal neuron dendrites and dendritic spines. Ma XM, etal., J Neurosci 2003 Nov 19;23(33):10593-603.
14. Kalirin Dbl-homology guanine nucleotide exchange factor 1 domain initiates new axon outgrowths via RhoG-mediated mechanisms. May V, etal., J Neurosci 2002 Aug 15;22(16):6980-90.
15. Association of KALRN, ADIPOQ, and FTO gene polymorphism in type 2 diabetic patients with coronary artery disease: possible predisposing markers. Mofarrah M, etal., Coron Artery Dis. 2016 Sep;27(6):490-6. doi: 10.1097/MCA.0000000000000386.
16. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
17. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
18. Neurexin-Neuroligin Synaptic Complex Regulates Schizophrenia-Related DISC1/Kal-7/Rac1 "Signalosome". Owczarek S, etal., Neural Plast. 2015;2015:167308. doi: 10.1155/2015/167308. Epub 2015 May 20.
19. Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action. Paskus JD, etal., Cell Rep. 2019 Dec 3;29(10):2944-2952.e5. doi: 10.1016/j.celrep.2019.10.115.
20. The neuronal Rho-GEF Kalirin-7 interacts with PDZ domain-containing proteins and regulates dendritic morphogenesis. Penzes P, etal., Neuron. 2001 Jan;29(1):229-42.
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PMID:9915831   PMID:10692441   PMID:10974569   PMID:12546821   PMID:14742910   PMID:15923627   PMID:16644733   PMID:18585704   PMID:18625710   PMID:18628310   PMID:19020030   PMID:19056867  
PMID:19625617   PMID:19889983   PMID:20333733   PMID:21880917   PMID:22458534   PMID:22738176   PMID:23116210   PMID:23288169   PMID:23516288   PMID:23742124   PMID:23825406   PMID:25146373  
PMID:25378388   PMID:25865668   PMID:26921771   PMID:27989699   PMID:28418645   PMID:30053369   PMID:30565792   PMID:30875016   PMID:32203420   PMID:32375403   PMID:38143048  



Kalrn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81179,703,345 - 80,309,210 (+)NCBIGRCr8
mRatBN7.21166,198,155 - 66,803,166 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1166,198,173 - 66,797,610 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1175,087,947 - 75,631,070 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01167,750,338 - 68,292,956 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01166,780,418 - 67,323,530 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01169,484,293 - 70,025,682 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1169,484,293 - 70,025,633 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01172,575,016 - 73,115,328 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41168,124,348 - 68,611,336 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11168,205,034 - 68,668,925 (+)NCBI
Celera1165,708,953 - 66,248,259 (+)NCBICelera
Cytogenetic Map11q22NCBI
KALRN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383124,033,369 - 124,726,325 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3124,033,369 - 124,726,325 (+)EnsemblGRCh38hg38GRCh38
GRCh373123,752,216 - 124,445,172 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363125,296,275 - 125,922,726 (+)NCBINCBI36Build 36hg18NCBI36
Celera3122,221,230 - 122,847,210 (+)NCBICelera
Cytogenetic Map3q21.1-q21.2NCBI
HuRef3121,187,838 - 121,814,322 (+)NCBIHuRef
CHM1_13123,776,558 - 124,403,021 (+)NCBICHM1_1
T2T-CHM13v2.03126,759,499 - 127,452,146 (+)NCBIT2T-CHM13v2.0
Kalrn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391633,789,443 - 34,393,647 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1633,789,443 - 34,393,902 (-)EnsemblGRCm39 Ensembl
GRCm381633,969,073 - 34,573,277 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1633,969,073 - 34,573,532 (-)EnsemblGRCm38mm10GRCm38
MGSCv371633,969,159 - 34,514,113 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361633,892,682 - 34,433,795 (-)NCBIMGSCv36mm8
Celera1634,453,093 - 34,990,407 (-)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1624.27NCBI
Kalrn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542723,184,739 - 23,816,811 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542723,184,751 - 23,823,128 (+)NCBIChiLan1.0ChiLan1.0
KALRN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22121,994,732 - 122,687,369 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13121,999,508 - 122,692,146 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03121,138,136 - 121,828,723 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13128,098,363 - 128,722,156 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3128,225,413 - 128,720,441 (+)Ensemblpanpan1.1panPan2
KALRN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13327,161,403 - 27,752,891 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3327,161,504 - 27,746,497 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3327,117,706 - 27,776,818 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03327,329,328 - 27,797,773 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3327,328,803 - 27,985,259 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13327,125,464 - 27,784,937 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03327,169,910 - 27,829,241 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03327,786,940 - 28,447,934 (+)NCBIUU_Cfam_GSD_1.0
Kalrn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602126,658,106 - 127,230,908 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936725572,868 - 1,139,142 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936725749,382 - 1,020,702 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KALRN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.113135,653,795 - 136,277,072 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213145,158,050 - 145,609,817 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KALRN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12256,106,677 - 56,820,004 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2256,151,819 - 56,754,538 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041109,573,807 - 110,217,834 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kalrn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624731121,122 - 752,942 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473154,934 - 756,707 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Kalrn
5285 total Variants

Predicted Target Of
Summary Value
Count of predictions:202
Count of miRNA genes:136
Interacting mature miRNAs:149
Transcripts:ENSRNOT00000002324, ENSRNOT00000016340, ENSRNOT00000049292
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 26 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)114545932375190161Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)111945620576331918Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat

1 to 10 of 26 rows
D11Mgh3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,422,148 - 66,422,316 (+)MAPPERmRatBN7.2
Rnor_6.01169,649,708 - 69,649,875NCBIRnor6.0
Rnor_5.01172,739,687 - 72,739,854UniSTSRnor5.0
RGSC_v3.41168,234,781 - 68,234,949RGDRGSC3.4
RGSC_v3.41168,234,782 - 68,234,949UniSTSRGSC3.4
RGSC_v3.11168,292,371 - 68,292,538RGD
Celera1165,874,140 - 65,874,287UniSTS
RH 3.4 Map11411.0UniSTS
RH 3.4 Map11411.0RGD
Cytogenetic Map11q22UniSTS
D11Arb4  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,422,141 - 66,422,377 (+)MAPPERmRatBN7.2
Rnor_6.01169,649,701 - 69,649,936NCBIRnor6.0
Rnor_5.01172,739,680 - 72,739,915UniSTSRnor5.0
RGSC_v3.41168,234,774 - 68,235,010RGDRGSC3.4
RGSC_v3.41168,234,775 - 68,235,010UniSTSRGSC3.4
RGSC_v3.11168,292,364 - 68,292,599RGD
Celera1165,874,133 - 65,874,348UniSTS
RH 3.4 Map11416.8UniSTS
RH 3.4 Map11416.8RGD
RH 2.0 Map11147.1RGD
SHRSP x BN Map1129.8399RGD
Cytogenetic Map11q22UniSTS
D11Got53  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81179,919,577 - 79,919,686 (+)Marker Load Pipeline
mRatBN7.21166,414,395 - 66,414,504 (+)MAPPERmRatBN7.2
Rnor_6.01169,641,939 - 69,642,047NCBIRnor6.0
Rnor_5.01172,731,918 - 72,732,026UniSTSRnor5.0
RGSC_v3.41168,227,012 - 68,227,121RGDRGSC3.4
RGSC_v3.41168,227,013 - 68,227,121UniSTSRGSC3.4
RGSC_v3.11168,284,602 - 68,284,710RGD
Celera1165,866,395 - 65,866,495UniSTS
RH 3.4 Map11416.9RGD
RH 3.4 Map11416.9UniSTS
RH 2.0 Map11147.0RGD
Cytogenetic Map11q22UniSTS
BE102756  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map11423.8UniSTS
Cytogenetic Map11q22UniSTS
RH137364  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,762,510 - 66,762,678 (+)MAPPERmRatBN7.2
Rnor_6.01169,990,587 - 69,990,754NCBIRnor6.0
Rnor_5.01173,080,299 - 73,080,466UniSTSRnor5.0
RGSC_v3.41168,575,790 - 68,575,957UniSTSRGSC3.4
Celera1166,213,376 - 66,213,543UniSTS
RH 3.4 Map11410.0UniSTS
Cytogenetic Map11q22UniSTS
BE110052  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,550,775 - 66,550,986 (+)MAPPERmRatBN7.2
Rnor_6.01169,778,868 - 69,779,078NCBIRnor6.0
Rnor_5.01172,868,257 - 72,868,467UniSTSRnor5.0
RGSC_v3.41168,363,209 - 68,363,419UniSTSRGSC3.4
Celera1166,001,487 - 66,001,697UniSTS
RH 3.4 Map11413.6UniSTS
Cytogenetic Map11q22UniSTS
BF396995  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,584,216 - 66,584,428 (+)MAPPERmRatBN7.2
Rnor_6.01169,812,304 - 69,812,515NCBIRnor6.0
Rnor_5.01172,901,599 - 72,901,810UniSTSRnor5.0
RGSC_v3.41168,396,645 - 68,396,856UniSTSRGSC3.4
Celera1166,034,975 - 66,035,186UniSTS
RH 3.4 Map11415.4UniSTS
Cytogenetic Map11q22UniSTS
AU046621  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01172,583,938 - 72,584,303NCBIRnor5.0
RGSC_v3.41168,082,751 - 68,083,111UniSTSRGSC3.4
Celera1165,717,382 - 65,717,746UniSTS
Cytogenetic Map11q22UniSTS
RH137626  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,797,618 - 66,797,774 (+)MAPPERmRatBN7.2
Rnor_6.01170,025,691 - 70,025,846NCBIRnor6.0
Rnor_5.01173,115,337 - 73,115,492UniSTSRnor5.0
RGSC_v3.41168,611,345 - 68,611,500UniSTSRGSC3.4
Celera1166,248,268 - 66,248,423UniSTS
Cytogenetic Map11q22UniSTS
RH138291  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,698,064 - 66,698,218 (+)MAPPERmRatBN7.2
Rnor_6.01169,926,149 - 69,926,302NCBIRnor6.0
Rnor_5.01173,015,452 - 73,015,605UniSTSRnor5.0
RGSC_v3.41168,511,288 - 68,511,441UniSTSRGSC3.4
Celera1166,148,872 - 66,149,025UniSTS
RH 3.4 Map11420.8UniSTS
Cytogenetic Map11q22UniSTS
AU049016  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,739,774 - 66,740,015 (+)MAPPERmRatBN7.2
mRatBN7.21166,739,924 - 66,740,015 (+)MAPPERmRatBN7.2
Rnor_6.01169,968,003 - 69,968,093NCBIRnor6.0
Rnor_6.01169,967,853 - 69,968,093NCBIRnor6.0
Rnor_5.01173,057,717 - 73,057,807UniSTSRnor5.0
Rnor_5.01173,057,567 - 73,057,807UniSTSRnor5.0
RGSC_v3.41168,552,992 - 68,553,232UniSTSRGSC3.4
RGSC_v3.41168,553,142 - 68,553,232UniSTSRGSC3.4
Celera1166,190,796 - 66,190,886UniSTS
Celera1166,190,646 - 66,190,886UniSTS
Cytogenetic Map11q22UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31


1 to 30 of 56 rows
RefSeq Transcripts NM_032062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 30 of 56 rows

Ensembl Acc Id: ENSRNOT00000016340   ⟹   ENSRNOP00000016340
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,198,173 - 66,628,157 (+)Ensembl
Rnor_6.0 Ensembl1169,739,384 - 69,856,241 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000049292   ⟹   ENSRNOP00000039072
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,254,969 - 66,797,610 (+)Ensembl
Rnor_6.0 Ensembl1169,484,293 - 70,025,633 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098731   ⟹   ENSRNOP00000078050
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,254,969 - 66,797,610 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101686   ⟹   ENSRNOP00000097769
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,688,941 - 66,797,589 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112350   ⟹   ENSRNOP00000084630
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,616,200 - 66,760,639 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114138   ⟹   ENSRNOP00000089775
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,198,173 - 66,797,610 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117056   ⟹   ENSRNOP00000094025
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,254,810 - 66,797,610 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118953   ⟹   ENSRNOP00000084297
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,254,682 - 66,797,610 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119829   ⟹   ENSRNOP00000083298
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,688,941 - 66,765,434 (+)Ensembl
RefSeq Acc Id: NM_032062   ⟹   NP_114451
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,760,161 - 80,302,770 (+)NCBI
mRatBN7.21166,254,969 - 66,797,610 (+)NCBI
Rnor_6.01169,484,293 - 70,025,682 (+)NCBI
Rnor_5.01172,575,016 - 73,115,328 (+)NCBI
RGSC_v3.41168,124,348 - 68,611,336 (+)RGD
Celera1165,708,953 - 66,248,259 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039088638   ⟹   XP_038944566
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,749 - 80,309,210 (+)NCBI
mRatBN7.21166,251,541 - 66,803,166 (+)NCBI
RefSeq Acc Id: XM_039088639   ⟹   XP_038944567
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,749 - 80,309,210 (+)NCBI
mRatBN7.21166,251,541 - 66,803,166 (+)NCBI
RefSeq Acc Id: XM_039088640   ⟹   XP_038944568
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,748 - 80,309,210 (+)NCBI
mRatBN7.21166,251,541 - 66,803,166 (+)NCBI
RefSeq Acc Id: XM_039088641   ⟹   XP_038944569
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,749 - 80,309,210 (+)NCBI
mRatBN7.21166,254,969 - 66,797,564 (+)NCBI
RefSeq Acc Id: XM_039088642   ⟹   XP_038944570
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,703,345 - 80,309,210 (+)NCBI
mRatBN7.21166,198,520 - 66,797,564 (+)NCBI
RefSeq Acc Id: XM_039088643   ⟹   XP_038944571
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,749 - 80,309,210 (+)NCBI
mRatBN7.21166,254,969 - 66,797,564 (+)NCBI
RefSeq Acc Id: XM_039088644   ⟹   XP_038944572
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,749 - 80,309,210 (+)NCBI
mRatBN7.21166,251,541 - 66,797,564 (+)NCBI
RefSeq Acc Id: XM_039088645   ⟹   XP_038944573
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,748 - 80,309,210 (+)NCBI
mRatBN7.21166,251,541 - 66,803,166 (+)NCBI
RefSeq Acc Id: XM_039088646   ⟹   XP_038944574
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,749 - 80,309,210 (+)NCBI
mRatBN7.21166,251,541 - 66,803,166 (+)NCBI
RefSeq Acc Id: XM_039088647   ⟹   XP_038944575
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,748 - 80,309,210 (+)NCBI
mRatBN7.21166,251,541 - 66,803,166 (+)NCBI
RefSeq Acc Id: XM_039088648   ⟹   XP_038944576
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,814,904 - 80,309,210 (+)NCBI
mRatBN7.21166,311,425 - 66,797,602 (+)NCBI
RefSeq Acc Id: XM_039088649   ⟹   XP_038944577
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,750 - 80,309,210 (+)NCBI
mRatBN7.21166,251,542 - 66,803,166 (+)NCBI
RefSeq Acc Id: XM_039088650   ⟹   XP_038944578
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,749 - 80,309,210 (+)NCBI
mRatBN7.21166,251,541 - 66,803,166 (+)NCBI
RefSeq Acc Id: XM_039088651   ⟹   XP_038944579
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,755 - 80,274,361 (+)NCBI
mRatBN7.21166,251,544 - 66,770,216 (+)NCBI
RefSeq Acc Id: XM_039088652   ⟹   XP_038944580
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,757 - 80,266,650 (+)NCBI
mRatBN7.21166,251,545 - 66,761,497 (+)NCBI
RefSeq Acc Id: XM_039088653   ⟹   XP_038944581
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,757 - 80,266,650 (+)NCBI
mRatBN7.21166,251,545 - 66,761,497 (+)NCBI
RefSeq Acc Id: XM_039088654   ⟹   XP_038944582
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,756 - 80,265,803 (+)NCBI
mRatBN7.21166,251,545 - 66,760,639 (+)NCBI
RefSeq Acc Id: XM_039088655   ⟹   XP_038944583
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,757 - 80,266,650 (+)NCBI
mRatBN7.21166,251,545 - 66,760,966 (+)NCBI
RefSeq Acc Id: XM_039088656   ⟹   XP_038944584
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,816,614 - 80,266,650 (+)NCBI
mRatBN7.21166,311,425 - 66,761,474 (+)NCBI
RefSeq Acc Id: XM_039088657   ⟹   XP_038944585
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81180,016,509 - 80,309,210 (+)NCBI
mRatBN7.21166,511,317 - 66,803,166 (+)NCBI
RefSeq Acc Id: XM_039088658   ⟹   XP_038944586
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,703,346 - 80,239,355 (+)NCBI
mRatBN7.21166,198,155 - 66,736,072 (+)NCBI
RefSeq Acc Id: XM_039088660   ⟹   XP_038944588
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,752 - 80,134,722 (+)NCBI
mRatBN7.21166,251,543 - 66,629,551 (+)NCBI
RefSeq Acc Id: XM_039088661   ⟹   XP_038944589
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,703,347 - 80,134,722 (+)NCBI
mRatBN7.21166,198,156 - 66,629,551 (+)NCBI
RefSeq Acc Id: XM_039088662   ⟹   XP_038944590
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,752 - 80,134,722 (+)NCBI
mRatBN7.21166,251,543 - 66,629,551 (+)NCBI
RefSeq Acc Id: XM_039088663   ⟹   XP_038944591
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,752 - 80,134,722 (+)NCBI
mRatBN7.21166,251,543 - 66,629,551 (+)NCBI
RefSeq Acc Id: XM_039088664   ⟹   XP_038944592
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,703,347 - 80,134,722 (+)NCBI
mRatBN7.21166,198,156 - 66,629,551 (+)NCBI
RefSeq Acc Id: XM_039088665   ⟹   XP_038944593
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,752 - 80,134,722 (+)NCBI
mRatBN7.21166,251,543 - 66,629,551 (+)NCBI
RefSeq Acc Id: XM_039088666   ⟹   XP_038944594
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,751 - 80,134,722 (+)NCBI
mRatBN7.21166,251,543 - 66,629,551 (+)NCBI
RefSeq Acc Id: XM_039088667   ⟹   XP_038944595
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,751 - 80,134,722 (+)NCBI
mRatBN7.21166,251,543 - 66,629,551 (+)NCBI
RefSeq Acc Id: XM_063270778   ⟹   XP_063126848
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,751 - 80,309,210 (+)NCBI
RefSeq Acc Id: XM_063270779   ⟹   XP_063126849
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,757 - 80,266,650 (+)NCBI
RefSeq Acc Id: XM_063270780   ⟹   XP_063126850
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,758 - 80,266,650 (+)NCBI
RefSeq Acc Id: XM_063270781   ⟹   XP_063126851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,757 - 80,265,803 (+)NCBI
RefSeq Acc Id: XM_063270782   ⟹   XP_063126852
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,759 - 80,266,650 (+)NCBI
RefSeq Acc Id: XM_063270783   ⟹   XP_063126853
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,760 - 80,266,650 (+)NCBI
RefSeq Acc Id: XM_063270784   ⟹   XP_063126854
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81180,193,785 - 80,309,210 (+)NCBI
RefSeq Acc Id: XM_063270785   ⟹   XP_063126855
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81180,193,790 - 80,309,210 (+)NCBI
RefSeq Acc Id: XM_063270786   ⟹   XP_063126856
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81180,194,073 - 80,265,803 (+)NCBI
RefSeq Acc Id: XM_063270787   ⟹   XP_063126857
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81180,194,077 - 80,265,803 (+)NCBI
RefSeq Acc Id: XM_063270788   ⟹   XP_063126858
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81180,194,078 - 80,265,803 (+)NCBI
RefSeq Acc Id: XM_063270789   ⟹   XP_063126859
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81180,194,075 - 80,265,803 (+)NCBI
RefSeq Acc Id: XM_063270790   ⟹   XP_063126860
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81180,194,076 - 80,265,803 (+)NCBI
1 to 30 of 64 rows
Protein RefSeqs NP_114451 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944566 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944567 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944568 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944569 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944570 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944571 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944572 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944573 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944574 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944575 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944576 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944577 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944578 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944579 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944580 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944581 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944582 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944583 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944584 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944585 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944586 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944588 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944589 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944590 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944591 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944592 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944593 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944594 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944595 (Get FASTA)   NCBI Sequence Viewer  
1 to 30 of 64 rows
1 to 5 of 52 rows
1 to 5 of 52 rows
RefSeq Acc Id: NP_114451   ⟸   NM_032062
- UniProtKB: A0A8I6GKY9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000016340   ⟸   ENSRNOT00000016340
Ensembl Acc Id: ENSRNOP00000039072   ⟸   ENSRNOT00000049292
RefSeq Acc Id: XP_038944586   ⟸   XM_039088658
- Peptide Label: isoform X27
- UniProtKB: A6IRJ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944589   ⟸   XM_039088661
- Peptide Label: isoform X29
- UniProtKB: A0A8L2Q7U3 (UniProtKB/TrEMBL),   A6IRJ4 (UniProtKB/TrEMBL)

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 40 of 112 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-21148 BioCyc
Ensembl Genes ENSRNOG00000001706 Ensembl, ENTREZGENE
  ENSRNOG00000072161 ENTREZGENE
Ensembl Transcript ENSRNOT00000016340 ENTREZGENE
  ENSRNOT00000101686 ENTREZGENE
Gene3D-CATH 1.20.58.60 UniProtKB/Swiss-Prot
  1.20.900.10 UniProtKB/Swiss-Prot
  2.30.29.30 UniProtKB/Swiss-Prot
  2.60.40.10 UniProtKB/Swiss-Prot
  3.40.525.10 UniProtKB/Swiss-Prot
  Phosphorylase Kinase, domain 1 UniProtKB/Swiss-Prot
  SH3 Domains UniProtKB/Swiss-Prot
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot
InterPro CRAL-TRIO_dom UniProtKB/Swiss-Prot
  CRAL-TRIO_dom_sf UniProtKB/Swiss-Prot
  DBL_dom_sf UniProtKB/Swiss-Prot
  DH-domain UniProtKB/Swiss-Prot
  FN3_dom UniProtKB/Swiss-Prot
  FN3_sf UniProtKB/Swiss-Prot
  Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_I-set UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
  Kalirin/TRIO UniProtKB/Swiss-Prot
  Kalirin_TRIO_PH_1 UniProtKB/Swiss-Prot
  Kalirin_TRIO_SH3_2 UniProtKB/Swiss-Prot
  Kinase-like_dom_sf UniProtKB/Swiss-Prot
  PH-like_dom_sf UniProtKB/Swiss-Prot
  PH_domain UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  RhoGEF_Guanine_NuclExch_SF UniProtKB/Swiss-Prot
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot
  SH3-like_dom_sf UniProtKB/Swiss-Prot
  SH3_domain UniProtKB/Swiss-Prot
  SOS1_NGEF_PH UniProtKB/Swiss-Prot
  Spectrin/alpha-actinin UniProtKB/Swiss-Prot
  Spectrin_repeat UniProtKB/Swiss-Prot
1 to 40 of 112 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-03-14 Kalrn  kalirin, RhoGEF kinase  Hapip  huntingtin-associated protein interacting protein (duo)  Symbol and Name updated to reflect Human and Mouse nomenclature 1299863 APPROVED
2002-08-07 Hapip  huntingtin-associated protein interacting protein (duo)      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_domains contains dual Rho GTPase guanine nucleotide exchange factor (GEF) domains that interact with Rac1 and RhoA 628431
gene_expression expressed mainly in the nervous system 628431
gene_physical_interaction binds to the cytoplasmic domain of peptidylglycine alpha-amidating monooxygenase (PAM), a membrane protein mediating neuropeptide biosynthesis 628431
gene_process participates in regulation of neuronal fiber extension and pathfinding during development 628431
gene_process initiates new axons and axonal outgrowth via RhoG-mediated mechanisms 628431