Rps3 (ribosomal protein S3) - Rat Genome Database

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Gene: Rps3 (ribosomal protein S3) Rattus norvegicus
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Symbol: Rps3 (Ensembl: Rps3l1)
Name: ribosomal protein S3 (Ensembl:ribosomal protein S3 like 1)
RGD ID: 619888
Description: Enables kinase binding activity. Involved in DNA damage response; cellular response to nerve growth factor stimulus; and regulation of apoptotic process. Located in dendrite and nucleus. Part of cytosolic small ribosomal subunit. Orthologous to human RPS3 (ribosomal protein S3); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 40S ribosomal protein S3; small ribosomal subunit protein uS3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81163,190,476 - 163,195,885 (-)NCBIGRCr8
mRatBN7.21153,778,363 - 153,783,663 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1153,777,472 - 153,783,680 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1161,774,286 - 161,779,586 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01168,954,438 - 168,959,738 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01161,827,972 - 161,833,272 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01164,435,868 - 164,441,167 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1164,435,878 - 164,441,167 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01170,637,728 - 170,643,027 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41156,811,470 - 156,816,770 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11156,889,883 - 156,895,183 (-)NCBI
Celera1151,861,094 - 151,866,394 (-)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
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Original Reference(s)
Rps3Rat3-methylglutaconic aciduria type 7b  ISORPS3 (Homo sapiens)8554872ClinVar Annotator: match by term: 3-methylglutaconic aciduria and type VIIBClinVarPMID:28492532
Rps3Ratintellectual disability  ISORPS3 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 
Object Symbol
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Reference
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Original Reference(s)
Rps3RatChromosomal Instability  ISORPS3 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25341047
Rps3Ratmelanoma  ISORPS3 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:22535842

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Original Reference(s)
Rps3Rat1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expressionEXP 6480464o and p'-DDT affects the expression of RPS3 mRNACTDPMID:17984292
Rps3Rat1,2-dimethylhydrazine increases expressionISORps3 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of RPS3 mRNACTDPMID:22206623
Rps3Rat1,2-dimethylhydrazine multiple interactionsISORps3 (Mus musculus)6480464Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of RPS3 mRNA]CTDPMID:22206623
Rps3Rat17alpha-ethynylestradiol affects expressionISORps3 (Mus musculus)6480464Ethinyl Estradiol affects the expression of RPS3 mRNACTDPMID:17555576
Rps3Rat17beta-estradiol multiple interactionsISORPS3 (Homo sapiens)64804643 more ...CTDPMID:11179685
Rps3Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of RPS3 proteinCTDPMID:32145629
Rps3Rat17beta-estradiol increases expressionISORPS3 (Homo sapiens)6480464Estradiol results in increased expression of RPS3 mRNACTDPMID:11179685
Rps3Rat17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactionsISORPS3 (Homo sapiens)6480464Metribolone promotes the reaction [NDRG1 protein binds to RPS3 protein]CTDPMID:17220478
Rps3Rat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISORps3 (Mus musculus)64804642 more ...CTDPMID:30294300
Rps3Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORPS3 (Homo sapiens)6480464Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of RPS3 mRNA]CTDPMID:11179685
Rps3Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of RPS3 mRNACTDPMID:33387578
Rps3Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORps3 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of RPS3 mRNACTDPMID:21570461
Rps3Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORps3 (Mus musculus)6480464Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to RPS3 promoter]CTDPMID:19654925
Rps3Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of RPS3 mRNA and Tetrachlorodibenzodioxin results in decreased expression of RPS3 proteinCTDPMID:16548065 and PMID:34747641
Rps3Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISORps3 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of RPS3 mRNACTDPMID:18796159
Rps3Rat2,6-dimethoxyphenol multiple interactionsISORPS3 (Homo sapiens)6480464[Sodium Chloride co-treated with pyrogallol 1 and 3-dimethyl ether] results in increased expression of and affects the localization of RPS3 proteinCTDPMID:38598786
Rps3Rat2-nitrofluorene increases expressionEXP 64804642-nitrofluorene results in increased expression of RPS3 mRNACTDPMID:15890375
Rps3Rat3,3'-diindolylmethane multiple interactionsISORPS3 (Homo sapiens)64804643 and 3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of RPS3 mRNA]CTDPMID:11179685
Rps3Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISORPS3 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of RPS3 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of RPS3 mRNACTDPMID:28628672
Rps3Rat4,4'-sulfonyldiphenol affects expressionISORps3 (Mus musculus)6480464bisphenol S affects the expression of RPS3 mRNACTDPMID:39298647

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Biological Process
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Original Reference(s)
Rps3Ratapoptotic process involved_inIEAUniProtKB-KW:KW-00531600115GO_REF:0000043UniProtGO_REF:0000043
Rps3Ratbase-excision repair involved_inISORPS3 (Homo sapiens)1624291 PMID:15518571RGDPMID:15518571
Rps3Ratcell division involved_inIEAUniProtKB-KW:KW-01321600115GO_REF:0000043UniProtGO_REF:0000043
Rps3Ratcellular response to hydrogen peroxide involved_inISORPS3 (Homo sapiens)1624291 PMID:23911537RGDPMID:23911537
Rps3Ratcellular response to nerve growth factor stimulus involved_inIDA 10402036PMID:20605787UniProt 
Rps3Ratcellular response to reactive oxygen species involved_inISORPS3 (Homo sapiens)1624291 PMID:23911537RGDPMID:23911537
Rps3Ratcellular response to tumor necrosis factor involved_inISORPS3 (Homo sapiens)1624291 PMID:18045535RGDPMID:18045535
Rps3Ratchromosome segregation involved_inISORPS3 (Homo sapiens)1624291 PMID:23131551RGDPMID:23131551
Rps3RatDNA damage response involved_inIDA 10402036PMID:20605787UniProt 
Rps3RatDNA damage response involved_inIEAUniProtKB-KW:KW-02271600115GO_REF:0000043UniProtGO_REF:0000043
Rps3RatDNA damage response involved_inISORPS3 (Homo sapiens)1624291 PMID:17560175RGDPMID:17560175
Rps3RatDNA repair involved_inISORPS3 (Homo sapiens)1624291 PMID:19059439RGDPMID:19059439
Rps3RatDNA repair involved_inIEAUniProtKB-KW:KW-02341600115GO_REF:0000043UniProtGO_REF:0000043
Rps3Ratnegative regulation of DNA repair involved_inISORPS3 (Homo sapiens)1624291 PMID:17049931RGDPMID:17049931
Rps3Ratnegative regulation of protein ubiquitination involved_inISORPS3 (Homo sapiens)1624291 PMID:19656744RGDPMID:19656744
Rps3Ratnegative regulation of translation involved_inISORPS3 (Homo sapiens)1624291 PMID:20217897RGDPMID:20217897
Rps3Ratpositive regulation of activated T cell proliferation involved_inISORPS3 (Homo sapiens)1624291 PMID:18045535RGDPMID:18045535
Rps3Ratpositive regulation of apoptotic signaling pathway involved_inISORPS3 (Homo sapiens)1624291 PMID:14988002RGDPMID:14988002
Rps3Ratpositive regulation of apoptotic signaling pathway involved_inIBAPANTHER:PTN000924666 and UniProtKB:P233961600115GO_REF:0000033GO_CentralGO_REF:0000033
Rps3Ratpositive regulation of base-excision repair involved_inISORPS3 (Homo sapiens)1624291 PMID:18973764RGDPMID:18973764
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Cellular Component
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Original Reference(s)
Rps3Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Rps3Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Rps3Ratcytoplasm located_inISORPS3 (Homo sapiens)1624291 PMID:14988002 more ...RGDPMID:14988002 more ...
Rps3Ratcytoplasm located_inISORps3 (Mus musculus)1624291 PMID:12388085RGDPMID:12388085
Rps3Ratcytoplasmic side of rough endoplasmic reticulum membrane located_inISORPS3 (Sus scrofa)1624291 PMID:24930395RGDPMID:24930395
Rps3Ratcytoskeleton located_inIEAUniProtKB-KW:KW-02061600115GO_REF:0000043UniProtGO_REF:0000043
Rps3Ratcytosol located_inISORPS3 (Homo sapiens)1624291 PMID:16814409 more ...RGDPMID:16814409 more ...
Rps3Ratcytosol located_inISORPS3 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Rps3Ratcytosolic ribosome part_ofISORPS3 (Homo sapiens)1624291 PMID:23636399RGDPMID:23636399
Rps3Ratcytosolic ribosome located_inIEAARBA:ARBA000265771600115GO_REF:0000117UniProtGO_REF:0000117
Rps3Ratcytosolic small ribosomal subunit  IDA 2300010 RGD 
Rps3Ratcytosolic small ribosomal subunit  IDA 2299084 RGD 
Rps3Ratcytosolic small ribosomal subunit part_ofISORps3 (Mus musculus)1624291 PMID:36517592RGDPMID:36517592
Rps3Ratcytosolic small ribosomal subunit part_ofIBAMGI:1350917 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rps3Ratcytosolic small ribosomal subunit part_ofISORPS3 (Homo sapiens)1624291 PMID:8706699RGDPMID:8706699
Rps3Ratcytosolic small ribosomal subunit part_ofISORPS3 (Sus scrofa)1624291 PMID:24930395RGDPMID:24930395
Rps3Ratcytosolic small ribosomal subunit  IDA 1599573 RGD 
Rps3Ratdendrite  IDA 2299084 RGD 
Rps3Ratendoplasmic reticulum located_inISORPS3 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Rps3Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
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Molecular Function
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Original Reference(s)
Rps3Ratclass I DNA-(apurinic or apyrimidinic site) endonuclease activity enablesIEARHEA:665921600115GO_REF:0000116RHEAGO_REF:0000116
Rps3Ratclass I DNA-(apurinic or apyrimidinic site) endonuclease activity enablesIEAEC:4.2.99.181600115GO_REF:0000003UniProtGO_REF:0000003
Rps3Ratdamaged DNA binding enablesISORPS3 (Homo sapiens)1624291 PMID:14706345 more ...RGDPMID:14706345 more ...
Rps3RatDNA binding enablesISORPS3 (Homo sapiens)1624291 PMID:18610840RGDPMID:18610840
Rps3RatDNA binding enablesIEAUniProtKB-KW:KW-02381600115GO_REF:0000043UniProtGO_REF:0000043
Rps3RatDNA endonuclease activity enablesISORPS3 (Homo sapiens)1624291 PMID:15707971 and PMID:20605787RGDPMID:15707971 and PMID:20605787
Rps3RatDNA N-glycosylase activity NOT|enablesISORPS3 (Homo sapiens)1624291 PMID:18610840RGDPMID:18610840
Rps3RatDNA-(apurinic or apyrimidinic site) endonuclease activity enablesISORps3 (Mus musculus)1624291 PMID:15707971RGDPMID:15707971
Rps3RatDNA-(apurinic or apyrimidinic site) endonuclease activity enablesISORPS3 (Homo sapiens)1624291 PMID:15707971 more ...RGDPMID:15707971 more ...
Rps3RatDNA-binding transcription factor binding enablesISORPS3 (Homo sapiens)1624291UniProtKB:O09139 and PMID:20605787RGDPMID:20605787
Rps3Ratenzyme binding enablesISORPS3 (Homo sapiens)1624291UniProtKB:O15527 more ...RGDPMID:15518571 more ...
Rps3RatHsp70 protein binding enablesISORPS3 (Homo sapiens)1624291 PMID:23911537RGDPMID:23911537
Rps3RatHsp90 protein binding enablesISORPS3 (Homo sapiens)1624291 PMID:23911537RGDPMID:23911537
Rps3Ratkinase binding enablesIPIUniProtKB:P4719610402036PMID:20605787UniProt 
Rps3Ratkinase binding enablesISORPS3 (Homo sapiens)1624291UniProtKB:P31749 and PMID:20605787RGDPMID:20605787
Rps3Ratlyase activity enablesIEAUniProtKB-KW:KW-04561600115GO_REF:0000043UniProtGO_REF:0000043
Rps3Ratmicrotubule binding enablesISORPS3 (Homo sapiens)1624291 PMID:23131551RGDPMID:23131551
Rps3RatmRNA binding enablesISORPS3 (Homo sapiens)1624291 PMID:18464793RGDPMID:18464793
Rps3Ratoxidized purine DNA binding enablesISORPS3 (Homo sapiens)1624291 PMID:14706345RGDPMID:14706345
Rps3Ratoxidized pyrimidine DNA binding enablesISORPS3 (Homo sapiens)1624291 PMID:19656744RGDPMID:19656744
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RGD Manual Annotations


  
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Original Reference(s)
Rps3Ratribosome biogenesis pathway   ISORPS3 (Homo sapiens)10002762 RGD 
Rps3Ratribosome biogenesis pathway   ISORPS3 (Homo sapiens)10002730 RGD 
Rps3Rattranslation pathway   ISORPS3 (Homo sapiens)10002762 RGD 

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#
Reference Title
Reference Citation
1. Structures of the human and Drosophila 80S ribosome. Anger AM, etal., Nature. 2013 May 2;497(7447):80-5. doi: 10.1038/nature12104.
2. The primary structure of rat ribosomal protein S3. Chan YL, etal., Arch Biochem Biophys 1990 Dec;283(2):546-50.
3. The isolation of eukaryotic ribosomal proteins. The purification and characterization of the 40 S ribosomal subunit proteins S2, S3, S4, S5, S6, S7, S8, S9, S13, S23/S24, S27, and S28. Collatz E, etal., J Biol Chem. 1976 Aug 10;251(15):4666-72.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Ribosomal protein S3, a new substrate of Akt, serves as a signal mediator between neuronal apoptosis and DNA repair. Lee SB, etal., J Biol Chem. 2010 Sep 17;285(38):29457-68. doi: 10.1074/jbc.M110.131367. Epub 2010 Jul 6.
7. Immunoelectron microscopic studies on the location of ribosomal proteins on the surface of the 40S ribosomal subunit from rat liver. Lutsch G, etal., Eur J Cell Biol. 1990 Feb;51(1):140-50.
8. Dendritic ribosomes suggest local protein synthesis during estrous synaptogenesis. McCarthy JB and Milner TA, Neuroreport. 2003 Jul 18;14(10):1357-60.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. Synaptotagmin 11 interacts with components of the RNA-induced silencing complex RISC in clonal pancreatic beta-cells. Milochau A, etal., FEBS Lett. 2014 Jun 27;588(14):2217-22. doi: 10.1016/j.febslet.2014.05.031. Epub 2014 May 29.
11. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
12. Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits. O'Donohue MF, etal., J Cell Biol. 2010 Sep 6;190(5):853-66. doi: 10.1083/jcb.201005117.
13. GOA pipeline RGD automated data pipeline
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. The RNA-binding protein MARTA2 regulates dendritic targeting of MAP2 mRNAs in rat neurons. Zivraj KH, etal., J Neurochem. 2013 Mar;124(5):670-84. doi: 10.1111/jnc.12079. Epub 2013 Jan 20.
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PMID:7775413   PMID:8706699   PMID:12388085   PMID:12477932   PMID:14706345   PMID:14988002   PMID:15489334   PMID:15518571   PMID:15707971   PMID:15883184   PMID:15950189   PMID:16635246  
PMID:16737853   PMID:16814409   PMID:16854843   PMID:17049931   PMID:17289661   PMID:17560175   PMID:18045535   PMID:18464793   PMID:18610840   PMID:18973764   PMID:19059439   PMID:19460357  
PMID:19656744   PMID:19946888   PMID:20041225   PMID:20217897   PMID:20458337   PMID:21170055   PMID:21399639   PMID:21423176   PMID:21700703   PMID:21871177   PMID:21968017   PMID:22082260  
PMID:22510408   PMID:22658674   PMID:22681889   PMID:22871113   PMID:23131551   PMID:23376485   PMID:23911537   PMID:23979707   PMID:24625528   PMID:24930395   PMID:26316108   PMID:29476059  
PMID:31904090   PMID:35352799   PMID:37087770  



Rps3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81163,190,476 - 163,195,885 (-)NCBIGRCr8
mRatBN7.21153,778,363 - 153,783,663 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1153,777,472 - 153,783,680 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1161,774,286 - 161,779,586 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01168,954,438 - 168,959,738 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01161,827,972 - 161,833,272 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01164,435,868 - 164,441,167 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1164,435,878 - 164,441,167 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01170,637,728 - 170,643,027 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41156,811,470 - 156,816,770 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11156,889,883 - 156,895,183 (-)NCBI
Celera1151,861,094 - 151,866,394 (-)NCBICelera
Cytogenetic Map1q32NCBI
RPS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381175,399,518 - 75,422,302 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1175,399,515 - 75,422,280 (+)EnsemblGRCh38hg38GRCh38
GRCh371175,110,562 - 75,133,346 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361174,788,210 - 74,794,381 (+)NCBINCBI36Build 36hg18NCBI36
Build 341174,788,221 - 74,794,380NCBI
Celera1172,418,313 - 72,424,484 (+)NCBICelera
Cytogenetic Map11q13.4NCBI
HuRef1171,407,971 - 71,430,530 (+)NCBIHuRef
CHM1_11174,994,110 - 75,016,921 (+)NCBICHM1_1
T2T-CHM13v2.01175,329,106 - 75,351,811 (+)NCBIT2T-CHM13v2.0
Rps3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39799,127,103 - 99,132,916 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl799,127,103 - 99,132,945 (-)EnsemblGRCm39 Ensembl
GRCm38799,477,896 - 99,483,709 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl799,477,896 - 99,483,738 (-)EnsemblGRCm38mm10GRCm38
MGSCv377106,626,406 - 106,632,219 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36799,346,578 - 99,357,709 (-)NCBIMGSCv36mm8
Celera799,802,893 - 99,808,694 (-)NCBICelera
Cytogenetic Map7E1NCBI
cM Map754.07NCBI
Rps3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541416,436,899 - 16,443,073 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541416,436,899 - 16,442,325 (-)NCBIChiLan1.0ChiLan1.0
RPS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2976,331,396 - 76,337,606 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11177,374,084 - 77,380,294 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01170,460,702 - 70,466,909 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11173,762,794 - 73,768,982 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1173,762,794 - 73,768,982 (+)Ensemblpanpan1.1panPan2
RPS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12123,180,515 - 23,187,034 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2123,180,515 - 23,187,034 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2122,946,186 - 22,952,704 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02123,383,445 - 23,389,963 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2123,383,445 - 23,389,963 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12123,181,778 - 23,188,296 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02123,378,071 - 23,384,591 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02123,295,999 - 23,302,524 (-)NCBIUU_Cfam_GSD_1.0
Rps3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494762,598,517 - 62,604,928 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364984,198,130 - 4,204,528 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364984,198,189 - 4,204,531 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl99,624,990 - 9,630,401 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.199,612,939 - 9,630,404 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2910,814,836 - 10,818,618 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RPS3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1166,629,895 - 66,636,462 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl166,629,954 - 66,635,344 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604359,169,727 - 59,176,327 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rps3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248171,710,768 - 1,716,224 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248171,710,768 - 1,715,923 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Rps3
15 total Variants

Predicted Target Of
Summary Value
Count of predictions:34
Count of miRNA genes:34
Interacting mature miRNAs:34
Transcripts:ENSRNOT00000023935
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 70 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61442Strs1Sensitivity to stroke QTL 17.4cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)1121767634166767634Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
1598866Bp287Blood pressure QTL 2875.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383668Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat

1 to 10 of 70 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000023935   ⟹   ENSRNOP00000023935
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1153,778,366 - 153,783,349 (-)Ensembl
Rnor_6.0 Ensembl1164,435,878 - 164,441,167 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105265   ⟹   ENSRNOP00000087646
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1153,777,799 - 153,783,679 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108507   ⟹   ENSRNOP00000079648
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1153,777,472 - 153,783,680 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114051   ⟹   ENSRNOP00000076445
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1153,777,729 - 153,783,680 (-)Ensembl
RefSeq Acc Id: NM_001009239   ⟹   NP_001009239
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81163,190,476 - 163,195,776 (-)NCBI
mRatBN7.21153,778,363 - 153,783,663 (-)NCBI
Rnor_6.01164,435,868 - 164,441,167 (-)NCBI
Rnor_5.01170,637,728 - 170,643,027 (-)NCBI
RGSC_v3.41156,811,470 - 156,816,770 (-)RGD
Celera1151,861,094 - 151,866,394 (-)RGD
Sequence:
RefSeq Acc Id: XM_063270251   ⟹   XP_063126321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81163,190,478 - 163,195,885 (-)NCBI
Protein RefSeqs NP_001009239 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126321 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH88450 (Get FASTA)   NCBI Sequence Viewer  
  EDM18402 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000079648
  ENSRNOP00000079648.1
GenBank Protein P62909 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001009239   ⟸   NM_001009239
- UniProtKB: P62909 (UniProtKB/Swiss-Prot),   A6I6I3 (UniProtKB/TrEMBL),   A0A8L2QCG7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000023935   ⟸   ENSRNOT00000023935
Ensembl Acc Id: ENSRNOP00000079648   ⟸   ENSRNOT00000108507
Ensembl Acc Id: ENSRNOP00000087646   ⟸   ENSRNOT00000105265
Ensembl Acc Id: ENSRNOP00000076445   ⟸   ENSRNOT00000114051
KH type-2

Name Modeler Protein Id AA Range Protein Structure
AF-P62909-F1-model_v2 AlphaFold P62909 1-243 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13690231
Promoter ID:EPDNEW_R752
Type:multiple initiation site
Name:Rps3_1
Description:ribosomal protein S3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01164,441,185 - 164,441,245EPDNEW


1 to 34 of 34 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-58389 BioCyc
Ensembl Genes ENSRNOG00000017418 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000108507 ENTREZGENE
  ENSRNOT00000108507.1 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.1140.32 UniProtKB/Swiss-Prot
  3.30.300.20 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7126819 IMAGE-MGC_LOAD
InterPro KH_dom-like_a/b UniProtKB/Swiss-Prot
  KH_dom_type_2 UniProtKB/Swiss-Prot
  KH_sf_prok-type UniProtKB/Swiss-Prot
  Ribosomal_S3_C UniProtKB/Swiss-Prot
  Ribosomal_S3_C_sf UniProtKB/Swiss-Prot
  Ribosomal_S3_CS UniProtKB/Swiss-Prot
  Ribosomal_S3_euk/arc UniProtKB/Swiss-Prot
KEGG Report rno:140654 UniProtKB/Swiss-Prot
MGC_CLONE MGC:95096 IMAGE-MGC_LOAD
NCBI Gene 140654 ENTREZGENE
PANTHER 30S/40S RIBOSOMAL PROTEIN S3 UniProtKB/Swiss-Prot
  40S RIBOSOMAL PROTEIN S3 UniProtKB/Swiss-Prot
Pfam KH_2 UniProtKB/Swiss-Prot
  Ribosomal_S3_C UniProtKB/Swiss-Prot
PhenoGen Rps3 PhenoGen
PROSITE KH_TYPE_2 UniProtKB/Swiss-Prot
  RIBOSOMAL_S3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000017418 RatGTEx
Superfamily-SCOP SSF54814 UniProtKB/Swiss-Prot
  SSF54821 UniProtKB/Swiss-Prot
UniProt A0A8I5ZK30_RAT UniProtKB/TrEMBL
  A0A8I6A8D6_RAT UniProtKB/TrEMBL
  A0A8L2QCG7 ENTREZGENE, UniProtKB/TrEMBL
  A6I6I3 ENTREZGENE, UniProtKB/TrEMBL
  P62909 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary P17073 UniProtKB/Swiss-Prot
  P47933 UniProtKB/Swiss-Prot
1 to 34 of 34 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Rps3  ribosomal protein S3      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Rps3  ribosomal protein S3      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_protein 243 amino acids and a molecular weight of 26,643 634046