RPS3 (ribosomal protein S3) - Rat Genome Database

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Gene: RPS3 (ribosomal protein S3) Canis lupus familiaris
Analyze
Symbol: RPS3
Name: ribosomal protein S3
RGD ID: 12109135
Description: ENCODES a protein that exhibits damaged DNA binding (ortholog); DNA endonuclease activity (ortholog); DNA N-glycosylase activity (ortholog); INVOLVED IN base-excision repair (ortholog); cellular response to hydrogen peroxide (ortholog); cellular response to nerve growth factor stimulus (ortholog); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; ASSOCIATED WITH 3-methylglutaconic aciduria type 7b (ortholog); Chromosomal Instability (ortholog); genetic disease (ortholog); FOUND IN cytoplasmic side of rough endoplasmic reticulum membrane (ortholog); cytosol (ortholog); cytosolic ribosome (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 40S ribosomal protein S3; small ribosomal subunit protein uS3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12123,180,515 - 23,187,034 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2123,180,515 - 23,187,034 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2122,946,186 - 22,952,704 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02123,383,445 - 23,389,963 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2123,383,445 - 23,389,963 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12123,181,778 - 23,188,296 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02123,378,071 - 23,384,591 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02123,295,999 - 23,302,524 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:16341006   PMID:18400176   PMID:22301074   PMID:30032202   PMID:37756605  


Genomics

Comparative Map Data
RPS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12123,180,515 - 23,187,034 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2123,180,515 - 23,187,034 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2122,946,186 - 22,952,704 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02123,383,445 - 23,389,963 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2123,383,445 - 23,389,963 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12123,181,778 - 23,188,296 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02123,378,071 - 23,384,591 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02123,295,999 - 23,302,524 (-)NCBIUU_Cfam_GSD_1.0
RPS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381175,399,518 - 75,422,302 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1175,399,515 - 75,422,280 (+)EnsemblGRCh38hg38GRCh38
GRCh371175,110,562 - 75,133,346 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361174,788,210 - 74,794,381 (+)NCBINCBI36Build 36hg18NCBI36
Build 341174,788,221 - 74,794,380NCBI
Celera1172,418,313 - 72,424,484 (+)NCBICelera
Cytogenetic Map11q13.4NCBI
HuRef1171,407,971 - 71,430,530 (+)NCBIHuRef
CHM1_11174,994,110 - 75,016,921 (+)NCBICHM1_1
T2T-CHM13v2.01175,329,106 - 75,351,811 (+)NCBIT2T-CHM13v2.0
Rps3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39799,127,103 - 99,132,916 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl799,127,103 - 99,132,945 (-)EnsemblGRCm39 Ensembl
GRCm38799,477,896 - 99,483,709 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl799,477,896 - 99,483,738 (-)EnsemblGRCm38mm10GRCm38
MGSCv377106,626,406 - 106,632,219 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36799,346,578 - 99,357,709 (-)NCBIMGSCv36mm8
Celera799,802,893 - 99,808,694 (-)NCBICelera
Cytogenetic Map7E1NCBI
cM Map754.07NCBI
Rps3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81163,190,476 - 163,195,885 (-)NCBIGRCr8
mRatBN7.21153,778,363 - 153,783,663 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1153,777,472 - 153,783,680 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1161,774,286 - 161,779,586 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01168,954,438 - 168,959,738 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01161,827,972 - 161,833,272 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01164,435,868 - 164,441,167 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1164,435,878 - 164,441,167 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01170,637,728 - 170,643,027 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41156,811,470 - 156,816,770 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11156,889,883 - 156,895,183 (-)NCBI
Celera1151,861,094 - 151,866,394 (-)NCBICelera
Cytogenetic Map1q32NCBI
Rps3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541416,436,899 - 16,443,073 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541416,436,899 - 16,442,325 (-)NCBIChiLan1.0ChiLan1.0
RPS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2976,331,396 - 76,337,606 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11177,374,084 - 77,380,294 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01170,460,702 - 70,466,909 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11173,762,794 - 73,768,982 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1173,762,794 - 73,768,982 (+)Ensemblpanpan1.1panPan2
Rps3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494762,598,517 - 62,604,928 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364984,198,130 - 4,204,528 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364984,198,189 - 4,204,531 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl99,624,990 - 9,630,401 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.199,612,939 - 9,630,404 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2910,814,836 - 10,818,618 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RPS3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1166,629,895 - 66,636,462 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl166,629,954 - 66,635,344 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604359,169,727 - 59,176,327 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rps3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248171,710,768 - 1,716,224 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248171,710,768 - 1,715,923 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RPS3
113 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High 4 12 5 6 2 10 4
Medium 1 5 10 6 1 6 6 10 8 2
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSCAFT00000008686   ⟹   ENSCAFP00000008052
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2123,180,515 - 23,187,034 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845021062   ⟹   ENSCAFP00845016559
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2123,383,445 - 23,389,963 (-)Ensembl
RefSeq Acc Id: NM_001313777   ⟹   NP_001300706
RefSeq Status: VALIDATED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12123,180,515 - 23,187,034 (-)NCBI
Dog10K_Boxer_Tasha2122,946,186 - 22,952,704 (-)NCBI
ROS_Cfam_1.02123,383,445 - 23,389,963 (-)NCBI
UMICH_Zoey_3.12123,181,778 - 23,188,296 (-)NCBI
UNSW_CanFamBas_1.02123,378,071 - 23,384,591 (-)NCBI
UU_Cfam_GSD_1.02123,295,999 - 23,302,524 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001300706 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein E2RH47 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000008052.3
  ENSCAFP00030029066.1
  ENSCAFP00030029127.1
  ENSCAFP00040027712.1
  ENSCAFP00805040264
  ENSCAFP00845016559
  ENSCAFP00845016559.1
RefSeq Acc Id: NP_001300706   ⟸   NM_001313777
- UniProtKB: E2RH47 (UniProtKB/Swiss-Prot),   A0A8C0JLD4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000008052   ⟸   ENSCAFT00000008686
RefSeq Acc Id: ENSCAFP00845016559   ⟸   ENSCAFT00845021062
Protein Domains
KH type-2

Promoters
RGD ID:13687188
Promoter ID:EPDNEW_C5257
Type:multiple initiation site
Name:RPS3_1
Description:ribosomal protein S3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12123,187,029 - 23,187,089EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000005402 Ensembl, UniProtKB/Swiss-Prot
  ENSCAFG00030018057 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSCAFG00040017211 UniProtKB/Swiss-Prot
  ENSCAFG00805028364 UniProtKB/Swiss-Prot
  ENSCAFG00845011844 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSCAFT00000008686.5 UniProtKB/Swiss-Prot
  ENSCAFT00030033312.1 UniProtKB/TrEMBL
  ENSCAFT00030033380.1 UniProtKB/Swiss-Prot
  ENSCAFT00040031863.1 UniProtKB/Swiss-Prot
  ENSCAFT00805051405 UniProtKB/Swiss-Prot
  ENSCAFT00845021062 ENTREZGENE
  ENSCAFT00845021062.1 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.1140.32 UniProtKB/Swiss-Prot
  3.30.300.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro KH_dom-like_a/b UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KH_dom_type_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KH_sf_prok-type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S3_C UniProtKB/Swiss-Prot
  Ribosomal_S3_C_sf UniProtKB/Swiss-Prot
  Ribosomal_S3_CS UniProtKB/Swiss-Prot
  Ribosomal_S3_euk/arc UniProtKB/Swiss-Prot
KEGG Report cfa:476804 UniProtKB/Swiss-Prot
NCBI Gene RPS3 ENTREZGENE
PANTHER 30S/40S RIBOSOMAL PROTEIN S3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  40S RIBOSOMAL PROTEIN S3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam KH_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S3_C UniProtKB/Swiss-Prot
PROSITE KH_TYPE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIBOSOMAL_S3 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54814 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54821 UniProtKB/Swiss-Prot
UniProt A0A8C0JLD4 ENTREZGENE
  A0A8C0NLM2_CANLF UniProtKB/TrEMBL
  E2RH47 ENTREZGENE, UniProtKB/Swiss-Prot
VGNC ID VGNC:45736 ENTREZGENE